Sid Gilman

Summary

Affiliation: University of Michigan
Country: USA

Publications

  1. ncbi request reprint Hereditary neuronal intranuclear inclusion disease with autonomic failure and cerebellar degeneration
    Raffaella Zannolli
    Department of Pediatrics, Obstetrics, and Reproductive Medicine, Section of Pediatrics, Policlinico Le Scotte, University of Siena, Siena, Italy
    Arch Neurol 59:1319-26. 2002
  2. ncbi request reprint Consensus statement on the diagnosis of multiple system atrophy
    S Gilman
    Department of Neurology, University of Michigan Medical Center, Ann Arbor 48109 0316, USA
    J Neurol Sci 163:94-8. 1999
  3. ncbi request reprint Pharmacologic management of ischemic stroke: relevance to stem cell therapy
    Sid Gilman
    Department of Neurology, The University of Michigan, 300 North Ingalls Street 3D15, Ann Arbor, MI 48105 0495, USA
    Exp Neurol 199:28-36. 2006
  4. ncbi request reprint REM sleep behavior disorder is related to striatal monoaminergic deficit in MSA
    S Gilman
    Department of Neurology, University of Michigan, Ann Arbor, USA
    Neurology 61:29-34. 2003
  5. ncbi request reprint Obstructive sleep apnea is related to a thalamic cholinergic deficit in MSA
    S Gilman
    Department of Neurology University of Michigan, Ann Arbor, USA
    Neurology 61:35-9. 2003
  6. ncbi request reprint Striatal monoamine terminals in Lewy body dementia and Alzheimer's disease
    Sid Gilman
    Department of Neurology, University of Michigan, Ann Arbor, MI 48109 0316, USA
    Ann Neurol 55:774-80. 2004
  7. ncbi request reprint Time course and outcome of recovery from stroke: relevance to stem cell treatment
    Sid Gilman
    Department of Neurology, University of Michigan, 300 North Ingalls St, Ann Arbor, MI 48109, USA
    Exp Neurol 199:37-41. 2006
  8. ncbi request reprint Differentiation of Alzheimer's disease from dementia with Lewy bodies utilizing positron emission tomography with [18F]fluorodeoxyglucose and neuropsychological testing
    Sid Gilman
    Department of Neurology, University of Michigan, Ann Arbor, MI 48109 0489, USA
    Exp Neurol 191:S95-S103. 2005
  9. ncbi request reprint The North American Multiple System Atrophy Study Group
    S Gilman
    Department of Neurology, University of Michigan, Ann Arbor, MI 48109 0489, USA
    J Neural Transm 112:1687-94. 2005
  10. ncbi request reprint Clinical effects of Abeta immunization (AN1792) in patients with AD in an interrupted trial
    S Gilman
    Department of Neurology, University of Michigan, 300 N Ingalls 3D15, Ann Arbor, MI 48109 0489, USA
    Neurology 64:1553-62. 2005

Research Grants

Detail Information

Publications42

  1. ncbi request reprint Hereditary neuronal intranuclear inclusion disease with autonomic failure and cerebellar degeneration
    Raffaella Zannolli
    Department of Pediatrics, Obstetrics, and Reproductive Medicine, Section of Pediatrics, Policlinico Le Scotte, University of Siena, Siena, Italy
    Arch Neurol 59:1319-26. 2002
    ..The disease has been found in monozygotic twins and in siblings. In 2 previously described families, the disorder has affected 2 generations...
  2. ncbi request reprint Consensus statement on the diagnosis of multiple system atrophy
    S Gilman
    Department of Neurology, University of Michigan Medical Center, Ann Arbor 48109 0316, USA
    J Neurol Sci 163:94-8. 1999
    ..The diagnosis of probable MSA requires the criterion for autonomic failure/urinary dysfunction plus poorly levodopa responsive parkinsonism or cerebellar ataxia. The diagnosis of definite MSA requires pathological confirmation...
  3. ncbi request reprint Pharmacologic management of ischemic stroke: relevance to stem cell therapy
    Sid Gilman
    Department of Neurology, The University of Michigan, 300 North Ingalls Street 3D15, Ann Arbor, MI 48105 0495, USA
    Exp Neurol 199:28-36. 2006
    ....
  4. ncbi request reprint REM sleep behavior disorder is related to striatal monoaminergic deficit in MSA
    S Gilman
    Department of Neurology, University of Michigan, Ann Arbor, USA
    Neurology 61:29-34. 2003
    ..To explore the neurochemical basis of REM sleep behavior disorder (RBD) in multiple-system atrophy (MSA)...
  5. ncbi request reprint Obstructive sleep apnea is related to a thalamic cholinergic deficit in MSA
    S Gilman
    Department of Neurology University of Michigan, Ann Arbor, USA
    Neurology 61:35-9. 2003
    ..To explore the neurochemical basis of obstructive sleep apnea (OSA) in multiple-system atrophy (MSA)...
  6. ncbi request reprint Striatal monoamine terminals in Lewy body dementia and Alzheimer's disease
    Sid Gilman
    Department of Neurology, University of Michigan, Ann Arbor, MI 48109 0316, USA
    Ann Neurol 55:774-80. 2004
    ..We conclude that PET with (+)-[(11)C]DTBZ differentiates DLB from AD, and decreased binding in AD may indicate subclinical DLB pathology in addition to AD pathology...
  7. ncbi request reprint Time course and outcome of recovery from stroke: relevance to stem cell treatment
    Sid Gilman
    Department of Neurology, University of Michigan, 300 North Ingalls St, Ann Arbor, MI 48109, USA
    Exp Neurol 199:37-41. 2006
    ....
  8. ncbi request reprint Differentiation of Alzheimer's disease from dementia with Lewy bodies utilizing positron emission tomography with [18F]fluorodeoxyglucose and neuropsychological testing
    Sid Gilman
    Department of Neurology, University of Michigan, Ann Arbor, MI 48109 0489, USA
    Exp Neurol 191:S95-S103. 2005
    ..Neuropsychological testing also differentiates the groups, and family ratings of motor functioning are as robust as PET in these later stages of the disorders...
  9. ncbi request reprint The North American Multiple System Atrophy Study Group
    S Gilman
    Department of Neurology, University of Michigan, Ann Arbor, MI 48109 0489, USA
    J Neural Transm 112:1687-94. 2005
    ....
  10. ncbi request reprint Clinical effects of Abeta immunization (AN1792) in patients with AD in an interrupted trial
    S Gilman
    Department of Neurology, University of Michigan, 300 N Ingalls 3D15, Ann Arbor, MI 48109 0489, USA
    Neurology 64:1553-62. 2005
    ..The authors report the results of a phase IIa immunotherapy trial of AN1792(QS-21) in patients with mild to moderate Alzheimer disease (AD) that was interrupted because of meningoencephalitis in 6% of immunized patients...
  11. ncbi request reprint Parkinsonian syndromes
    Sid Gilman
    Department of Neurology, University of Michigan, 300 North Ingalls, 3D15, Ann Arbor, MI 48109 0489, USA
    Clin Geriatr Med 22:827-42, vi. 2006
    ..This article reviews the epidemiology, pathology, clinical features, diagnosis, and management of these disorders...
  12. ncbi request reprint Functional imaging with positron emission tomography in multiple system atrophy
    S Gilman
    Department of Neurology, University of Michigan, Ann Arbor, MI 48109 0489, USA
    J Neural Transm 112:1647-55. 2005
    ....
  13. ncbi request reprint Consensus statement on the diagnosis of multiple system atrophy. American Autonomic Society and American Academy of Neurology
    S Gilman
    Department of Neurology, University of Michigan Medical Center, Ann Arbor 48109 0316, USA
    Clin Auton Res 8:359-62. 1998
    ..The diagnosis of probable MSA requires the criterion for autonomic failure/urinary dysfunction plus poor levodopa responsive parkinsonism or cerebellar ataxia. The diagnosis of definite MSA requires pathological confirmation...
  14. ncbi request reprint Consensus statement on the diagnosis of multiple system atrophy
    S Gilman
    Department of Neurology, University of Michigan Medical Center, Ann Arbor 48109 0316, USA
    J Auton Nerv Syst 74:189-92. 1998
    ..The diagnosis of probable MSA requires the criterion for autonomic failure/urinary dysfunction plus poorly levodopa responsive parkinsonism or cerebellar ataxia. The diagnosis of definite MSA requires pathological confirmation...
  15. pmc Second consensus statement on the diagnosis of multiple system atrophy
    S Gilman
    Department of Neurology, University of Michigan, 300 N Ingalls St, 3D15, Ann Arbor, MI 48109 5489, USA
    Neurology 71:670-6. 2008
    ..Since then, clinical, laboratory, neuropathologic, and imaging studies have advanced the field, requiring a fresh evaluation of diagnostic criteria. We held a second consensus conference in 2007 and present the results here...
  16. pmc Joint position sense and vibration sense: anatomical organisation and assessment
    S Gilman
    Department of Neurology, University of Michigan Medical Center, 1500 E Medical Center Drive, 1914 Taubman Center, Ann Arbor 48109 0316, USA
    J Neurol Neurosurg Psychiatry 73:473-7. 2002
    ..Clinical testing of these modalities requires simultaneous stimulation of tactile receptors; hence this review will include information about the receptors and pathways responsible for tactile sensation...
  17. pmc Comparing fludeoxyglucose F18-PET assessment of regional cerebral glucose metabolism and [11C]dihydrotetrabenazine-PET in evaluation of early dementia and mild cognitive impairment
    Roger L Albin
    VA Ann Arbor Health System Geriatrics Research, Education, and Clinical Center, and Department of Neurology, University of Michigan, Ann Arbor, MI 48109 2200, USA
    Arch Neurol 67:440-6. 2010
    ....
  18. doi request reprint Differentiating Alzheimer's disease from dementia with Lewy bodies and Parkinson's disease with (+)-[11C]dihydrotetrabenazine positron emission tomography
    Robert A Koeppe
    Division of Nuclear Medicine, Department of Radiology, The University of Michigan, Ann Arbor, MI, USA
    Alzheimers Dement 4:S67-76. 2008
    ..We used positron emission tomography (PET) in attempts to differentiate these disorders...
  19. ncbi request reprint 11C-DTBZ and 18F-FDG PET measures in differentiating dementias
    Robert A Koeppe
    Division of Nuclear Medicine, Department of Radiology, University of Michigan School of Medicine, 3480 Kresge III, Box 0552, Ann Arbor, MI 48109, USA
    J Nucl Med 46:936-44. 2005
    ....
  20. pmc Assessment of mild dementia with amyloid and dopamine terminal positron emission tomography
    James F Burke
    Department of Neurology, University of Michigan, and University of Michigan Hospitals, Room B1 G505 UH, 1500 East Medical Center Drive, Ann Arbor, MI 48109 0028, USA
    Brain 134:1647-57. 2011
    ....
  21. pmc Heterogeneity of cholinergic denervation in Parkinson's disease without dementia
    Nicolaas I Bohnen
    Department of Radiology, Division of Nuclear Medicine, University of Michigan, Ann Arbor, Michigan 48105 9755, USA
    J Cereb Blood Flow Metab 32:1609-17. 2012
    ..Results also show independent cognitive effects for both cholinergic and dopaminergic system changes in nondemented PD subjects...
  22. pmc Assessing mild cognitive impairment with amyloid and dopamine terminal molecular imaging
    Roger L Albin
    Department of Neurology, University of Michigan, Ann Arbor, Michigan 48109 2200, USA
    J Nucl Med 54:887-93. 2013
    ..We evaluated PET-based classification of neurodegenerative pathology in mild cognitive impairment (MCI)...
  23. ncbi request reprint Validation of a polysomnographic score for REM sleep behavior disorder
    Flavia B Consens
    University of Michigan, Ann Arbor, MI, USA
    Sleep 28:993-7. 2005
    ..We sought to validate this method in a larger sample of patients and control subjects...
  24. pmc Pattern of cardiac sympathetic denervation in idiopathic Parkinson disease studied with 11C hydroxyephedrine PET
    Ka Kit Wong
    Division of Nuclear Medicine, Department of Radiology, University of Michigan Medical Center, University of Michigan, 1500 E Medical Center Dr, B1G505G, Ann Arbor, MI 48105, USA
    Radiology 265:240-7. 2012
    ....
  25. ncbi request reprint PET measurement of cardiac and nigrostriatal denervation in Parkinsonian syndromes
    David M Raffel
    Division of Nuclear Medicine, Department of Radiology, University of Michigan, Ann Arbor, Michigan, USA
    J Nucl Med 47:1769-77. 2006
    ..Also, the relationship between cardiac denervation and nigrostriatal denervation was investigated by measuring striatal presynaptic monoaminergic nerve density with PET and (11)C-dihydrotetrabenazine ((11)C-DTBZ)...
  26. pmc EMG variance during polysomnography as an assessment for REM sleep behavior disorder
    Joseph W Burns
    Michigan Tech Research Institute, Michigan Technological University, Ann Arbor, MI 48105, USA
    Sleep 30:1771-8. 2007
    ..We therefore developed a computerized metric to assess EMG variance and compared the results to those previously published for visual scoring, bed partner-rated RBD symptom scores, and clinical assessments by sleep medicine specialists...
  27. ncbi request reprint PET measures of benzodiazepine receptors in progressive supranuclear palsy
    N L Foster
    Department of Neurology, University of Michigan at Ann Arbor, 48109 0316, USA
    Neurology 54:1768-73. 2000
    ..To evaluate the integrity of neurons containing benzodiazepine receptors in metabolically affected regions of the brain in patients with clinically diagnosed progressive supranuclear palsy (PSP)...
  28. ncbi request reprint Unilateral striatal lesions in the cat disrupt well-learned motor plans in a GO/NO-GO reaching task
    J W Aldridge
    Department of Neurology, University of Michigan, Ann Arbor 48104 1687, USA
    Exp Brain Res 113:379-93. 1997
    ..Our findings suggest that the basal ganglia facilitate the fluent and rapid execution of sequences of well-learned sensorimotor behavior, but the representations of motor plans are not stored in the basal ganglia...
  29. pmc Cerebral cortical and subcortical cholinergic deficits in parkinsonian syndromes
    S Gilman
    Department of Neurology, University of Michigan Health System, Ann Arbor, USA
    Neurology 74:1416-23. 2010
    ..We studied cholinergic innervation in these disorders as compared to age-appropriate normal control subjects...
  30. ncbi request reprint Patterns of neuropsychological performance in multiple system atrophy compared to sporadic and hereditary olivopontocerebellar atrophy
    S Berent
    Division of Neuropsychology, Department of Psychiatry, University of Michigan Medical Center, Ann Arbor, MI 48109 0840, USA
    Brain Cogn 50:194-206. 2002
    ..Patients with MSA had greater neuropsychological dysfunction, particularly in memory and other "higher order" cognitive processes, than patients with either sOPCA or dOPCA...
  31. pmc Prospective differentiation of multiple system atrophy from Parkinson disease, with and without autonomic failure
    Axel Lipp
    Department of Neurology, Mayo Clinic, Rochester, MN 55905, USA
    Arch Neurol 66:742-50. 2009
    ....
  32. ncbi request reprint Autoradiographic localization of inhibitory and excitatory amino acid neurotransmitter receptors in human normal and olivopontocerebellar atrophy cerebellar cortex
    R L Albin
    Department of Neurology, University of Michigan, Ann Arbor 48104
    Brain Res 522:37-45. 1990
    ..Our normal human and OPCA data are largely consistent with animal data about the cellular localization of cerebellar cortical amino acid neurotransmitter receptors...
  33. ncbi request reprint Altered excitatory and inhibitory amino acid receptor binding in hippocampus of patients with temporal lobe epilepsy
    J W McDonald
    Department of Neurology, University of Michigan, Ann Arbor
    Ann Neurol 29:529-41. 1991
    ..The data indicate that excitatory and inhibitory amino acid receptors are altered in the hippocampus of patients with temporal lobe epilepsy...
  34. ncbi request reprint G2019S mutation in the leucine-rich repeat kinase 2 gene is not associated with multiple system atrophy
    Laurie J Ozelius
    Department of Molecular Genetics, Albert Einstein College of Medicine, Bronx, New York, USA
    Mov Disord 22:546-9. 2007
    ..We conclude that the G2019S mutation in the LRRK2 gene is unlikely to be associated with MSA...
  35. ncbi request reprint Development and validation of the Unified Multiple System Atrophy Rating Scale (UMSARS)
    Gregor K Wenning
    Department of Neurology, University of Innsbruck, Austria
    Mov Disord 19:1391-402. 2004
    ..Based on our findings, the UMSARS appears to be a multidimensional, reliable, and valid scale for semiquantitative clinical assessments of MSA patients...
  36. pmc A roadmap for the prevention of dementia: the inaugural Leon Thal Symposium
    Zaven S Khachaturian
    Alzheimers Dement 4:156-63. 2008
  37. ncbi request reprint Potential outcome measures and trial design issues for multiple system atrophy
    Susanne May
    Department of Family and Preventive Medicine, University of California, San Diego, La Jolla, California 92093 0717, USA
    Mov Disord 22:2371-7. 2007
    ..The UMSARS Motor Examination score exhibited the most favorable characteristics as an outcome measure for a therapeutic trial in MSA with 1 year of follow-up...
  38. ncbi request reprint Horsley was the first to use electrical stimulation of the human cerebral cortex intraoperatively
    Joel A Vilensky
    Department of Anatomy, Indiana University School of Medicine, Fort Wayne, Indiana, USA
    Surg Neurol 58:425-6. 2002
    ..Sir Victor Horsley apparently first used electrical stimulation diagnostically in 1884 and slightly later (1886) to define epileptic foci...
  39. ncbi request reprint Unexpected abundance of pathological tau in progressive supranuclear palsy white matter
    Victoria Zhukareva
    Department of Pathology and Laboratory Medicine, Center for Neurodegenerative Disease Research, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 4283, USA
    Ann Neurol 60:335-45. 2006
    ..To investigate whether biochemical insoluble tau with 4 (4R) and/or 3 (3R) microtubule-binding repeats accumulate in white as well as gray matter in progressive supranuclear palsy (PSP), a neurodegenerative tauopathy...
  40. ncbi request reprint What do people at risk for Alzheimer disease think about surrogate consent for research?
    Dale B Schenk
    Neurology 66:1785-6. 2006
  41. ncbi request reprint Relationship between neuropsychological and emotional functioning in severe chronic alcoholism
    Doug Johnson-Greene
    Department of Physical Medicine and Rehabilitation, Johns Hopkins University School of Medicine, Baltimore, MD 21239, USA
    Clin Neuropsychol 16:300-9. 2002
    ....
  42. ncbi request reprint Sir Victor Horsley, Mr John Marshall, the nervi nervorum, and pain: more than a century ahead of their time
    Joel A Vilensky
    Department of Anatomy and Cell Biology, Indiana University School of Medicine, Fort Wayne 46805, USA
    Arch Neurol 62:499-501. 2005

Research Grants2

  1. Conference on the Diagnosis of Multiple System Atrophy
    Sid Gilman; Fiscal Year: 2006
    ..This conference will assist with early diagnosis by developing new guidelines for diagnosis using newly available imaging and neuropathological criteria. ..