F D Gilliland

Summary

Affiliation: University of Southern California
Country: USA

Publications

  1. pmc Glutathione S-transferase P1, maternal smoking, and asthma in children: a haplotype-based analysis
    Yu Fen Li
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA
    Environ Health Perspect 116:409-15. 2008
  2. pmc Prostate-specific antigen testing accuracy in community practice
    Richard M Hoffman
    Department of Medicine, New Mexico VA Health Care System, Albuquerque, New Mexico, USA
    BMC Fam Pract 3:19. 2002
  3. ncbi request reprint Effects of glutathione S-transferase M1, maternal smoking during pregnancy, and environmental tobacco smoke on asthma and wheezing in children
    Frank D Gilliland
    Department of Preventive Medicine, University of Southern California Keck School of Medicine, 1540 Alcazar Street, CHP 236, Los Angeles, CA 90033, USA
    Am J Respir Crit Care Med 166:457-63. 2002
  4. ncbi request reprint Effects of glutathione S-transferase P1, M1, and T1 on acute respiratory illness in school children
    Frank D Gilliland
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, 1540 Alcazar Street, Los Angeles, CA 90053, USA
    Am J Respir Crit Care Med 166:346-51. 2002
  5. pmc Outdoor air pollution, genetic susceptibility, and asthma management: opportunities for intervention to reduce the burden of asthma
    Frank D Gilliland
    University of Southern California, Keck School of Medicine, Department of Preventive Medicine, 1540 Alcazar St, CHP 236, Los Angeles, CA 90033, USA
    Pediatrics 123:S168-73. 2009
  6. ncbi request reprint Uranium mining and lung cancer among Navajo men in New Mexico and Arizona, 1969 to 1993
    F D Gilliland
    Department of Preventive Medicine, Southern California Environmental Health Sciences Center, USA
    J Occup Environ Med 42:278-83. 2000
  7. pmc Maternal smoking during pregnancy, environmental tobacco smoke exposure and childhood lung function
    F D Gilliland
    Department of Preventive Medicine, University of Southern California School of Medicine, Los Angeles, California 90033, USA
    Thorax 55:271-6. 2000
  8. pmc Effect of spirometer temperature on FEV1 in a longitudinal epidemiological study
    F D Gilliland
    University of Southern California, School of Medicine, Department of Preventive Medicine, Los Angeles 90033, USA
    Occup Environ Med 56:718-20. 1999
  9. pmc Glutathione-S-transferase (GST) P1, GSTM1, exercise, ozone and asthma incidence in school children
    T Islam
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California Los Angeles, Los Angeles, CA 90033, USA
    Thorax 64:197-202. 2009
  10. doi request reprint The effect of ambient air pollution on exhaled nitric oxide in the Children's Health Study
    K Berhane
    Dept of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90089 9011, USA
    Eur Respir J 37:1029-36. 2011

Detail Information

Publications87

  1. pmc Glutathione S-transferase P1, maternal smoking, and asthma in children: a haplotype-based analysis
    Yu Fen Li
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA
    Environ Health Perspect 116:409-15. 2008
    ..Glutathione S-transferase P1 (GSTP1) plays a role in a spectrum of respiratory diseases; however, the effects of sequence variation across the entire locus in asthma pathogenesis have yet to be determined...
  2. pmc Prostate-specific antigen testing accuracy in community practice
    Richard M Hoffman
    Department of Medicine, New Mexico VA Health Care System, Albuquerque, New Mexico, USA
    BMC Fam Pract 3:19. 2002
    ..Most data on prostate-specific antigen (PSA) testing come from urologic cohorts comprised of volunteers for screening programs. We evaluated the diagnostic accuracy of PSA testing for detecting prostate cancer in community practice...
  3. ncbi request reprint Effects of glutathione S-transferase M1, maternal smoking during pregnancy, and environmental tobacco smoke on asthma and wheezing in children
    Frank D Gilliland
    Department of Preventive Medicine, University of Southern California Keck School of Medicine, 1540 Alcazar Street, CHP 236, Los Angeles, CA 90033, USA
    Am J Respir Crit Care Med 166:457-63. 2002
    ..Among children with GSTM1 (+) genotype, in utero exposure was not associated with asthma or wheezing. Our findings indicate that there are important long-term effects of in utero exposure in a genetically susceptible group of children...
  4. ncbi request reprint Effects of glutathione S-transferase P1, M1, and T1 on acute respiratory illness in school children
    Frank D Gilliland
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, 1540 Alcazar Street, Los Angeles, CA 90053, USA
    Am J Respir Crit Care Med 166:346-51. 2002
    ..80; 95% confidence interval, 0.65-0.99). GSTM1 and T1 genotypes were not associated with respiratory illness. We conclude that GSTP1 genotype influences the risk or severity of respiratory infections in school-aged children...
  5. pmc Outdoor air pollution, genetic susceptibility, and asthma management: opportunities for intervention to reduce the burden of asthma
    Frank D Gilliland
    University of Southern California, Keck School of Medicine, Department of Preventive Medicine, 1540 Alcazar St, CHP 236, Los Angeles, CA 90033, USA
    Pediatrics 123:S168-73. 2009
    ..A second approach involves induction of enzymatic antioxidant defenses, especially for individuals with at-risk genetic variants of key antioxidant enzymes...
  6. ncbi request reprint Uranium mining and lung cancer among Navajo men in New Mexico and Arizona, 1969 to 1993
    F D Gilliland
    Department of Preventive Medicine, Southern California Environmental Health Sciences Center, USA
    J Occup Environ Med 42:278-83. 2000
    ..The Navajo experience with uranium mining is a unique example of exposure in a single occupation accounting for the majority of lung cancers in an entire population...
  7. pmc Maternal smoking during pregnancy, environmental tobacco smoke exposure and childhood lung function
    F D Gilliland
    Department of Preventive Medicine, University of Southern California School of Medicine, Los Angeles, California 90033, USA
    Thorax 55:271-6. 2000
    ..Exposure to environmental tobacco smoke (ETS) during childhood and in utero exposure to maternal smoking are associated with adverse effects on lung growth and development...
  8. pmc Effect of spirometer temperature on FEV1 in a longitudinal epidemiological study
    F D Gilliland
    University of Southern California, School of Medicine, Department of Preventive Medicine, Los Angeles 90033, USA
    Occup Environ Med 56:718-20. 1999
    ....
  9. pmc Glutathione-S-transferase (GST) P1, GSTM1, exercise, ozone and asthma incidence in school children
    T Islam
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California Los Angeles, Los Angeles, CA 90033, USA
    Thorax 64:197-202. 2009
    ....
  10. doi request reprint The effect of ambient air pollution on exhaled nitric oxide in the Children's Health Study
    K Berhane
    Dept of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90089 9011, USA
    Eur Respir J 37:1029-36. 2011
    ..In summary, short-term increases in PM₂.₅, PM₁₀ and O₃ were associated with airway inflammation independent of asthma and allergy status, with PM₁₀ effects significantly higher in the warm season...
  11. ncbi request reprint Environmental tobacco smoke and absenteeism related to respiratory illness in schoolchildren
    F D Gilliland
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA
    Am J Epidemiol 157:861-9. 2003
    ..44, 95% CI: 1.04, 2.00). Therefore, ETS exposure is associated with increased respiratory-related school absenteeism among children, especially those with asthma...
  12. ncbi request reprint The effects of ambient air pollution on school absenteeism due to respiratory illnesses
    F D Gilliland
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles 90033, USA
    Epidemiology 12:43-54. 2001
    ..7)] compared with communities with high average levels [38.1% (95% CI = 8.5-75.8)]. Increased school absenteeism from O3 exposure in children is an important adverse effect of ambient air pollution worthy of public policy consideration...
  13. doi request reprint In utero smoke exposure, glutathione S-transferase P1 haplotypes, and respiratory illness-related absence among schoolchildren
    Made Wenten
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA
    Pediatrics 123:1344-51. 2009
    ....
  14. doi request reprint Exhaled nitric oxide, susceptibility and new-onset asthma in the Children's Health Study
    T M Bastain
    Dept of Preventive Medicine, Keck School of Medicine, 1540 Alcazar Street, CHP 236, Los Angeles, CA 90033, USA
    Eur Respir J 37:523-31. 2011
    ..Our results indicate that children with elevated F(eNO) are at increased risk for new-onset asthma, especially if they have no parental history of asthma...
  15. pmc Transforming growth factor- 1 C-509T polymorphism, oxidant stress, and early-onset childhood asthma
    Muhammad T Salam
    Department of Preventive Medicine, USC Keck School of Medicine, 1540 Alcazar Street, CHP 236, Los Angeles, CA 90033, USA
    Am J Respir Crit Care Med 176:1192-9. 2007
    ..Tobacco smoke and traffic emissions induce airway inflammation and modulate TGF-beta1 gene expression. We hypothesized that the effects of functional TGF-beta1 variants on asthma occurrence vary by these exposures...
  16. pmc Ozone, oxidant defense genes, and risk of asthma during adolescence
    Talat Islam
    M D Department of Preventive Medicine, USC Keck School of Medicine, 1540 Alcazar Street, CHP 236, Los Angeles, CA 90033, USA
    Am J Respir Crit Care Med 177:388-95. 2008
    ....
  17. pmc Associations of tumor necrosis factor G-308A with childhood asthma and wheezing
    Yu Fen Li
    Department of Preventive Medicine, USC Keck School of Medicine, 1540 Alcazar Street, CHP 236, Los Angeles, CA 90033, USA
    Am J Respir Crit Care Med 173:970-6. 2006
    ....
  18. ncbi request reprint Radon progeny exposure and lung cancer risk among non-smoking uranium miners
    F D Gilliland
    Department of Preventive Medicine and Norris Comprehensive Cancer Center, University of Southern California, School of Medicine, Los Angeles 90089 9013, USA
    Health Phys 79:365-72. 2000
    ..As in studies of non-smokers and smokers combined, the exposure response relationship in never-smokers was consistent with a decreased slope at higher WLM, which resulted, in part, from an inverse dose rate effect...
  19. pmc Genetic variations in nitric oxide synthase and arginase influence exhaled nitric oxide levels in children
    M T Salam
    Department of Preventive Medicine, University of Southern California Keck School of Medicine, Los Angeles, CA, USA
    Allergy 66:412-9. 2011
    ..The aims of the study were to evaluate the role of genetic variations in nitric oxide synthases and arginases on FeNO in children and to assess the influence of asthma and respiratory allergy on these genetic associations...
  20. pmc Functional variants in the catalase and myeloperoxidase genes, ambient air pollution, and respiratory-related school absences: an example of epistasis in gene-environment interactions
    Made Wenten
    Department of Preventive Medicine, USC Keck School of Medicine, Los Angeles, CA 90033, USA
    Am J Epidemiol 170:1494-501. 2009
    ..03). The association of respiratory-illness absences with functional variants in CAT and MPO that differ by air pollution levels illustrates the need to consider genetic epistasis in assessing gene-environment interactions...
  21. pmc Roles of arginase variants, atopy, and ozone in childhood asthma
    Muhammad T Salam
    Department of Preventive Medicine, University of Southern California Keck School of Medicine, Los Angeles, Calif 90033, USA
    J Allergy Clin Immunol 123:596-602, 602.e1-8. 2009
    ..Arginases (encoded by ARG1 and ARG2 genes) might play an important role in asthma pathogenesis through effects on nitrosative stress. Arginase expression is upregulated in asthma and varies with T(H)2 cytokine levels and oxidative stress...
  22. ncbi request reprint Physical activity and breast cancer risk in hispanic and non-hispanic white women
    F D Gilliland
    Division of Occupational and Environmental Health, Department of Preventive Medicine, and Norris Comprehensive Cancer Center, University of Southern California Health Sciences Center, Los Angeles, CA, USA
    Am J Epidemiol 154:442-50. 2001
    ..The effects of physical activity were independent from reproductive factors, usual body mass index, body mass index at age 18, adult weight gain, and total energy intake...
  23. pmc A theoretical basis for investigating ambient air pollution and children's respiratory health
    F D Gilliland
    Department of Preventive Medicine, University of Southern California School of Medicine, Los Angeles 90033, USA
    Environ Health Perspect 107:403-7. 1999
    ....
  24. ncbi request reprint Effects of maternal smoking during pregnancy and environmental tobacco smoke on asthma and wheezing in children
    F D Gilliland
    Keck School of Medicine, Department of Preventive Medicine, University of Southern California, Los Angeles, California 90033, USA
    Am J Respir Crit Care Med 163:429-36. 2001
    ..that ETS operates as a cofactor with other insults such as intercurrent infections as a trigger of wheezing attacks, rather than as a factor that induces asthma, whereas in utero exposure acts to increase physician-diagnosed asthma..
  25. ncbi request reprint Intraindividual reproducibility of nasal allergic responses to diesel exhaust particles indicates a susceptible phenotype
    Theresa M Bastain
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, 1540 Alcazar Street, CHP 236, Los Angeles, CA 90033, USA
    Clin Immunol 109:130-6. 2003
    ....
  26. pmc Prenatal tobacco smoke exposure affects global and gene-specific DNA methylation
    Carrie V Breton
    Department of Preventive Medicine, University of Southern California, Keck School of Medicine, Los Angeles, CA 90033, USA
    Am J Respir Crit Care Med 180:462-7. 2009
    ..Prenatal exposure to tobacco smoke increases the risk for diseases later in the child's life that may be mediated through alterations in DNA methylation...
  27. pmc Microsomal epoxide hydrolase, glutathione S-transferase P1, traffic and childhood asthma
    Muhammad T Salam
    Department of Preventive Medicine, University of Southern California Keck School of Medicine, Los Angeles, California 90033, USA
    Thorax 62:1050-7. 2007
    ..A study was undertaken to investigate associations of variants in EPHX1, GSTM1, GSTP1 and GSTT1 with asthma and the relationships between asthma, EPHX1 metabolic phenotypes and exposure to sources of PAHs...
  28. pmc Birth outcomes and prenatal exposure to ozone, carbon monoxide, and particulate matter: results from the Children's Health Study
    Muhammad T Salam
    Department of Preventive Medicine, University of Southern California, Keck School of Medicine, Los Angeles, California 90033, USA
    Environ Health Perspect 113:1638-44. 2005
    ..1-42.2 g), but this association was reduced and not significant after adjusting for O3. In summary, O3 exposure during the second and third trimesters and CO exposure during the first trimester were associated with reduced birth weight...
  29. pmc Variation in the GST mu locus and tobacco smoke exposure as determinants of childhood lung function
    Carrie V Breton
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, 90033 USA
    Am J Respir Crit Care Med 179:601-7. 2009
    ..The glutathione S-transferases (GSTs) are important detoxification enzymes...
  30. pmc TNF-308 modifies the effect of second-hand smoke on respiratory illness-related school absences
    Made Wenten
    Division of Environmental Health, Department of Preventive Medicine, Keck School of Medicine of USC, 1540 Alcazar Street, Los Angeles, CA 90033, USA
    Am J Respir Crit Care Med 172:1563-8. 2005
    ..The role of genetic susceptibility in risk for adverse effects from SHS has not been extensively investigated in children...
  31. ncbi request reprint Intercellular adhesion molecule-1 and childhood asthma
    Yu Fen Li
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, CHP 236, Los Angeles, CA 90033, USA
    Hum Genet 117:476-84. 2005
    ..3, 95% CI 0.1-0.8), as compared with two copies of the AGA haplotype. Consistent with information on variant function, the 241A and 469G variants may indicate haplotypes that are associated with reduced risk for asthma...
  32. ncbi request reprint Associations of weight, weight change, and body mass with breast cancer risk in Hispanic and non-Hispanic white women
    Made Wenten
    Division of Occupational and Environmental Health, Department of Preventive Medicine, and Norris Comprehensive Cancer Center, University of Southern California Health Sciences Center, Los Angeles, CA, USA
    Ann Epidemiol 12:435-4. 2002
    ..A wealth of studies have examined the effects of weight, weight gain, and obesity on breast cancer risk; however, few have examined this relationship in Hispanic white women, a population with the highest rate of obesity in the U.S...
  33. ncbi request reprint Family history and risk of breast cancer in hispanic and non-hispanic women: the New Mexico Women's Health Study
    R Li
    Department of Preventive Medicine, and Norris Comprehensive Cancer Center, University of Southern California Health Sciences Center, USA
    Cancer Causes Control 12:747-53. 2001
    ..CONCLUSIONS: The results indicate that Hispanic women with a family history of breast cancer are at increased risk of breast cancer...
  34. ncbi request reprint Biologic characteristics of interval and screen-detected breast cancers
    F D Gilliland
    Department of Preventive Medicine and the Norris Comprehensive Cancer Center, University of Southern California, Keck School of Medicine, Los Angeles, USA
    J Natl Cancer Inst 92:743-9. 2000
    ..To determine whether markers of tumor growth rate are associated with risk of an interval cancer, we conducted a population-based study with the use of data collected statewide by the New Mexico Mammography Project...
  35. ncbi request reprint Recent evidence for adverse effects of residential proximity to traffic sources on asthma
    Muhammad T Salam
    Department of Preventive Medicine, University of Southern California Keck School of Medicine, Los Angeles, California 90033, USA
    Curr Opin Pulm Med 14:3-8. 2008
    ..In this review we have considered publications from 2006-2007 that examined the impact of residential traffic-related exposures on asthma occurrence and severity...
  36. ncbi request reprint Impact of respiratory illness on expiratory flow rates in normal, asthmatic, and allergic children
    Edward B Rappaport
    Department of Preventive Medicine, University of Southern California, Los Angeles 90089, USA
    Pediatr Pulmonol 34:112-21. 2002
    ..We conclude that RI in children who are well enough to attend school may reduce expiratory flow rates. These effects are greater for children with active asthma or hay fever than in those without, and may be inversely related to age...
  37. pmc Relationship between air pollution, lung function and asthma in adolescents
    Talat Islam
    Department of Preventive Medicine, Keck School of Medicine, Los Angeles, California 90033, USA
    Thorax 62:957-63. 2007
    ..A study was undertaken to determine whether lung function is associated with new onset asthma and whether this relationship varies by exposure to ambient air pollutants...
  38. ncbi request reprint Glutathione S-transferase P1 and NADPH quinone oxidoreductase polymorphisms are associated with aberrant promoter methylation of P16(INK4a) and O(6)-methylguanine-DNA methyltransferase in sputum
    Frank D Gilliland
    Keck School of Medicine, Department of Preventive Medicine and Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA 90089 9021, USA
    Cancer Res 62:2248-52. 2002
    ....
  39. ncbi request reprint Endogenous and exogenous sex steroid hormones and asthma and wheeze in young women
    Muhammad T Salam
    Department of Preventive Medicine, University of Southern California Keck School of Medicine, Los Angeles 90033, USA
    J Allergy Clin Immunol 117:1001-7. 2006
    ..Emerging evidence suggests that both endogenous and exogenous sex steroid hormones may influence the occurrence of asthma and wheeze among women...
  40. pmc Glutathione s-transferases M1 and P1 prevent aggravation of allergic responses by secondhand smoke
    Frank D Gilliland
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, 1540 Alcazar Street, CHP 236, Los Angeles, CA 90033, USA
    Am J Respir Crit Care Med 174:1335-41. 2006
    ..Glutathione S-transferases (GSTs) metabolize reactive oxygen species and detoxify electrophilic xenobiotics present in SHS and DEPs...
  41. ncbi request reprint Dietary magnesium, potassium, sodium, and children's lung function
    Frank D Gilliland
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA
    Am J Epidemiol 155:125-31. 2002
    ..7%, 95% confidence interval: -5.2, -0.1) and forced vital capacity (-2.4%, 95% confidence interval: -4.7, -0.1). In summary, low magnesium and potassium intakes were associated with lower lung volumes and flows...
  42. pmc Regular smoking and asthma incidence in adolescents
    Frank D Gilliland
    Department of Preventive Medicine, Keck School of Medicine of USC, 1540 Alcazar Street, CHP 236, Los Angeles, CA 90033, USA
    Am J Respir Crit Care Med 174:1094-100. 2006
    ....
  43. pmc Health effects of the 2003 Southern California wildfires on children
    Nino Kunzli
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, School of Public Health, University of California, Los Angeles, CA, USA
    Am J Respir Crit Care Med 174:1221-8. 2006
    ..In late October 2003, Southern California wildfires burned more than 3,000 km2. The wildfires produced heavy smoke that affected several communities participating in the University of Southern California Children's Health Study (CHS)...
  44. doi request reprint Relationships of online exhaled, offline exhaled, and ambient nitric oxide in an epidemiologic survey of schoolchildren
    William S Linn
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
    J Expo Sci Environ Epidemiol 19:674-81. 2009
    ..Conclusions: Either online or offline measurement of exhaled NO and concurrent ambient NO can be useful in field epidemiology. Influence of ambient NO on exhaled NO should be examined carefully, particularly for offline measurements...
  45. pmc Genetic variation in the glutathione synthesis pathway, air pollution, and children's lung function growth
    Carrie V Breton
    Department of Preventive Medicine, USC Keck School of Medicine, 1540 Alcazar Street, CHP 236, Los Angeles, CA 90033, USA
    Am J Respir Crit Care Med 183:243-8. 2011
    ..Glutathione plays an important role in antioxidant and inflammatory processes in the lung. Alterations in glutathione metabolism are a central feature of several chronic lung diseases...
  46. ncbi request reprint Effects of early onset asthma and in utero exposure to maternal smoking on childhood lung function
    Frank D Gilliland
    Department of Preventive Medicine, USC Keck School of Medicine, 1540 Alcazar Street, CHP 236, Los Angeles, CA 90033, USA
    Am J Respir Crit Care Med 167:917-24. 2003
    ..We found little evidence for effects from environmental tobacco smoke exposure alone. In summary, deficits in lung function were largest among children with in utero exposure and early onset asthma...
  47. ncbi request reprint Effects of glutathione-S-transferase M1, T1, and P1 on childhood lung function growth
    Frank D Gilliland
    Department of Preventive Medicine, University of Southern California Keck School of Medicine, Los Angeles, California 90033, USA
    Am J Respir Crit Care Med 166:710-6. 2002
    ..We conclude that GSTM1 and GSTP1 genotypes are associated with lung function growth in school children...
  48. pmc Effects of in utero and childhood tobacco smoke exposure and beta2-adrenergic receptor genotype on childhood asthma and wheezing
    Chengwei Wang
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, 1540 Alcazar St, CHP 236, Los Angeles, CA 90033, USA
    Pediatrics 122:e107-14. 2008
    ....
  49. ncbi request reprint Obesity and the risk of newly diagnosed asthma in school-age children
    Frank D Gilliland
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA
    Am J Epidemiol 158:406-15. 2003
    ..77, 95% CI: 1.26, 2.49) than in allergic children (RR = 1.16, 95% CI: 0.63, 2.15). The authors conclude that being overweight is associated with an increased risk of new-onset asthma in boys and in nonallergic children...
  50. doi request reprint Role of inducible nitric oxide synthase in asthma risk and lung function growth during adolescence
    Talat Islam
    Department of Preventive Medicine, USC Keck School of Medicine, University of Southern California, 1540 Alcazar Street, CHP 236, Los Angeles, CA 90033, USA
    Thorax 65:139-45. 2010
    ..Because nitrosative stress affects respiratory health, it was hypothesised that variants in NOS2A are associated with asthma incidence and lung function growth during adolescence...
  51. ncbi request reprint Children's lung function and antioxidant vitamin, fruit, juice, and vegetable intake
    Frank D Gilliland
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA
    Am J Epidemiol 158:576-84. 2003
    ..In summary, lung function levels were lower in children with inadequate dietary antioxidant vitamin intake...
  52. ncbi request reprint Effect of glutathione-S-transferase M1 and P1 genotypes on xenobiotic enhancement of allergic responses: randomised, placebo-controlled crossover study
    Frank D Gilliland
    Department of Preventive Medicine, University of Southern California, Keck School of Medicine, Los Angeles, CA 90033, USA
    Lancet 363:119-25. 2004
    ..We tested the hypothesis that null genotypes for GSTM1 and GSTT1, and GSTP1 codon 105 variants (I105 and V105) are key regulators of the adjuvant effects of diesel exhaust particles on allergic responses...
  53. doi request reprint Extended exhaled nitric oxide analysis in field surveys of schoolchildren: a pilot test
    William S Linn
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
    Pediatr Pulmonol 44:1033-42. 2009
    ..Extended NO analysis holds promise for investigating environmental and genetic determinants of regional airway inflammatory states...
  54. ncbi request reprint Maternal and grandmaternal smoking patterns are associated with early childhood asthma
    Yu Fen Li
    Department of Preventive Medicine, USC Keck School of Medicine, 1540 Alcazar St, CHP 236, Los Angeles, CA 90033, USA
    Chest 127:1232-41. 2005
    ..To investigate the associations of maternal and grandmaternal smoking before, during, and after pregnancy with childhood asthma...
  55. ncbi request reprint 5-year urinary and sexual outcomes after radical prostatectomy: results from the prostate cancer outcomes study
    David F Penson
    Department of Urology, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA
    J Urol 173:1701-5. 2005
    ..In this study we assessed temporal changes in urinary and sexual function up to 5 years following radical prostatectomy in a population based cohort...
  56. ncbi request reprint Racial/Ethnic differences in functional outcomes in the 5 years after diagnosis of localized prostate cancer
    Terri Kang Johnson
    University of Southern California Keck School of Medicine, Dept of Preventive Medicine, 1441 Eastlake Ave, Rm 3427A, MC9175, Los Angeles, CA 90089 9175, USA
    J Clin Oncol 22:4193-201. 2004
    ..We investigated racial/ethnic differences in functional outcomes up to 5 years after diagnosis among men with aggressively treated localized prostate cancer...
  57. pmc Exhaled nitric oxide in a population-based study of southern California schoolchildren
    William S Linn
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
    Respir Res 10:28. 2009
    ..Our aim was to identify significant predictors of FeNO in an initial cross-sectional survey of southern California schoolchildren, part of a larger longitudinal study of asthma incidence...
  58. ncbi request reprint Maternal fish consumption during pregnancy and risk of early childhood asthma
    Muhammad T Salam
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA
    J Asthma 42:513-8. 2005
    ..04; 95% CI = 1.18-3.51). Our results suggest that maternal oily fish intake during pregnancy may protect offspring from asthma; however, eating fish sticks during pregnancy may increase asthma risk in children...
  59. ncbi request reprint Trends in Gleason score for prostate cancer diagnosed between 1983 and 1993
    F D Gilliland
    Department of Preventive Medicine and the Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, California, USA
    J Urol 165:846-50. 2001
    ..There was little change in the proportion of Gleason score 7, 8, 9 and 10 tumors between the 2 periods...
  60. ncbi request reprint Health outcomes after external-beam radiation therapy for clinically localized prostate cancer: results from the Prostate Cancer Outcomes Study
    A S Hamilton
    Keck School of Medicine of the University of Southern California, Department of Preventive Medicine, Los Angeles, CA 90089 9175, USA
    J Clin Oncol 19:2517-26. 2001
    ..Effects of external-beam radiotherapy for prostate cancer among a population-based cohort were assessed...
  61. ncbi request reprint Hormone replacement therapy and breast carcinoma risk in Hispanic and non-Hispanic women
    Rui Li
    Division of Occupational and Environmental Health, Department of Preventive Medicine, University of Southern California Health Sciences Center, Los Angeles 90033, USA
    Cancer 95:960-8. 2002
    ..Epidemiologic studies report inconsistent findings regarding the relationship between HRT and postmenopausal breast carcinoma risk and there is little information on the HRT-associated risk among minority women...
  62. ncbi request reprint Mode of delivery is associated with asthma and allergy occurrences in children
    Muhammad T Salam
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles 90033, USA
    Ann Epidemiol 16:341-6. 2006
    ..In this study, we examined the associations between birth by cesarean section (C-section) and atopic disease occurrence in childhood...
  63. ncbi request reprint Effects of ethnicity, family income, and education on dietary intake among adolescents
    Bin Xie
    University of Southern California, Keck School of Medicine, Department of Preventive Medicine, Los Angeles 90033, USA
    Prev Med 36:30-40. 2003
    ....
  64. pmc Genotypes in matrix metalloproteinase 9 are a risk factor for COPD
    Yohannes Tesfaigzi
    Lovelace Respiratory Research Institute, 2425 Ridgecrest Drive, SE, Albuquerque, NM 87108, USA
    Int J Chron Obstruct Pulmon Dis 1:267-78. 2006
    ..No association of this polymorphism was found with decline in pulmonary function. These studies show that variants of the MMP-9 gene are associated with COPD in this cohort of veterans...
  65. ncbi request reprint Treatment of erectile dysfunction following therapy for clinically localized prostate cancer: patient reported use and outcomes from the Surveillance, Epidemiology, and End Results Prostate Cancer Outcomes Study
    Robert A Stephenson
    From the Division of Urology, University of Utah School of Medicine, Salt Lake City, Utah 8411132, USA
    J Urol 174:646-50; discussion 650. 2005
    ..We report use and treatment outcomes in a 5-year interval in a population based cohort from the Surveillance, Epidemiology, and End Results Prostate Cancer Outcomes Study...
  66. ncbi request reprint Multiplicity of abnormal promoter methylation in lung adenocarcinomas from smokers and never smokers
    Kevin K Divine
    Lung Cancer Program, Lovelace Respiratory Research Institute, Albuquerque, NM 87108, USA
    Int J Cancer 114:400-5. 2005
    ..Adenocarcinomas may develop through 2 distinct processes: multiple gene inactivations through promoter hypermethylation and activation of the K-ras gene...
  67. pmc Relationship of obesity and physical activity with C-peptide, leptin, and insulin-like growth factors in breast cancer survivors
    Melinda L Irwin
    Department of Epidemiology and Public Health, Yale School of Medicine, P O Box 208034, New Haven, CT 06520 8034, USA
    Cancer Epidemiol Biomarkers Prev 14:2881-8. 2005
    ..Few studies have examined the associations between obesity, physical activity, and these hormones/peptides among breast cancer survivors...
  68. pmc A testing framework for identifying susceptibility genes in the presence of epistasis
    Joshua Millstein
    National Oceanic and Atmospheric Administration National Marine Fisheries Service, Alaska Fisheries Science Center, Seattle, WA 98115, USA
    Am J Hum Genet 78:15-27. 2006
    ..In an independent data set consisting primarily of African American and Asian American children, these three genes also showed a significant association with asthma status (P = .0008)...
  69. pmc Racial differences in initial treatment for clinically localized prostate cancer. Results from the prostate cancer outcomes study
    Richard M Hoffman
    Medicine Service, New Mexico VA Health Care System, Albuquerque, NM 87108, USA
    J Gen Intern Med 18:845-53. 2003
    ..We examined whether there were racial differences in initial treatment for clinically localized prostate cancer and investigated whether demographic, socioeconomic, clinical, or tumor characteristics could explain any racial differences...
  70. ncbi request reprint Effects of misattribution in assigning cause of death on prostate cancer mortality rates
    Richard M Hoffman
    Department of Medicine, New Mexico VA Health Care System, Albuquerque, NM 87108, USA
    Ann Epidemiol 13:450-4. 2003
    ..Estimate the magnitude of misattribution in death certification and to determine whether misattribution could explain temporal trends in New Mexico prostate cancer mortality...
  71. ncbi request reprint Family history, Hispanic ethnicity, and prostate cancer risk
    S Noell Stone
    Epidemiology and Cancer Control Unit, The New Mexico Tumor Registry, University of New Mexico, 2325 Camino de Salud NE, Albuquerque, New Mexico 87106 5306, USA
    Ethn Dis 13:233-9. 2003
    ..7, 95% CI 1.5-4.7) and non-Hispanic Whites (NHW) (OR 2.0, 95% CI 1.3-3.1), suggesting that having a family history of CaP is a risk factor for both ethnic groups...
  72. pmc Physical activity, body mass index, and mammographic density in postmenopausal breast cancer survivors
    Melinda L Irwin
    Department of Epidemiology and Public Health, Yale School of Medicine, New Haven, CT 06520 8034, USA
    J Clin Oncol 25:1061-6. 2007
    ....
  73. ncbi request reprint Cross-sectional and longitudinal comparisons of health-related quality of life between patients with prostate carcinoma and matched controls
    Richard M Hoffman
    Medicine Service, New Mexico Veterans Affairs Health Care System, Albuquerque, NM 87108, USA
    Cancer 101:2011-9. 2004
    ..Prostate carcinoma and treatments affect health-related quality of life (HRQOL). The authors prospectively compared prostate and general HRQOL between prostate carcinoma cases and an age-matched and ethnicity-matched control group...
  74. ncbi request reprint Promoter hypermethylation of the O6-methylguanine-DNA methyltransferase gene: more common in lung adenocarcinomas from never-smokers than smokers and associated with tumor progression
    Leah C Pulling
    Lung Cancer Program, Lovelace Respiratory Research Institute, Albuquerque, New Mexico 87108 L C P, K K D, D M K, S A B
    Cancer Res 63:4842-8. 2003
    ..This study also suggests that K-ras activation is independent of MGMT methylation...
  75. pmc Physical activity levels before and after a diagnosis of breast carcinoma: the Health, Eating, Activity, and Lifestyle (HEAL) study
    Melinda L Irwin
    Department of Epidemiology and Public Health, Yale School of Medicine, New Haven, Connecticut 06520, USA
    Cancer 97:1746-57. 2003
    ....
  76. ncbi request reprint Patient satisfaction with treatment decisions for clinically localized prostate carcinoma. Results from the Prostate Cancer Outcomes Study
    Richard M Hoffman
    Medicine Service, New Mexico VA Health Care System, Albuquerque, New Mexico 87108, USA
    Cancer 97:1653-62. 2003
    ....
  77. ncbi request reprint Plutonium targets the p16 gene for inactivation by promoter hypermethylation in human lung adenocarcinoma
    Steven A Belinsky
    Lovelace Respiratory Research Institute, Lung Cancer Program, 2425 Ridgecrest Drive SE, Albuquerque, NM 87108, USA
    Carcinogenesis 25:1063-7. 2004
    ..Here we demonstrate that exposure to plutonium may elevate the risk for adenocarcinoma through specifically targeting the p16 gene for inactivation by promoter methylation...
  78. pmc Physical activity levels among breast cancer survivors
    Melinda L Irwin
    Department of Epidemiology and Public Health, Yale School of Medicine, New Haven, CT 06520 8034, USA
    Med Sci Sports Exerc 36:1484-91. 2004
    ....
  79. ncbi request reprint Gene promoter methylation in plasma and sputum increases with lung cancer risk
    Steven A Belinsky
    Lovelace Respiratory Research Institute, Albuquerque, NM 87108, USA
    Clin Cancer Res 11:6505-11. 2005
    ..The prevalence for methylation of seven and three genes was examined in DNA from sputum and plasma, respectively, from women at different risk for lung cancer...
  80. ncbi request reprint Aberrant promoter methylation in bronchial epithelium and sputum from current and former smokers
    Steven A Belinsky
    Lung Cancer Program, Lovelace Respiratory Research Institute, 2425 Ridgecrest Drive SE, Albuquerque, New Mexico 87108, USA
    Cancer Res 62:2370-7. 2002
    ....
  81. pmc Pre-diagnosis physical activity and mammographic density in breast cancer survivors
    Melinda L Irwin
    Department of Epidemiology and Public Health, Yale School of Medicine, New Haven, CT 06520 8034, USA
    Breast Cancer Res Treat 95:171-8. 2006
    ....
  82. pmc Influence of pre- and postdiagnosis physical activity on mortality in breast cancer survivors: the health, eating, activity, and lifestyle study
    Melinda L Irwin
    Department of Epidemiology and Public Health, Yale School of Medicine, P O Box 208034, New Haven, CT 06520 8034, USA
    J Clin Oncol 26:3958-64. 2008
    ..To investigate the association between pre- and postdiagnosis physical activity (as well as change in prediagnosis to postdiagnosis physical activity) and mortality among women with breast cancer...
  83. pmc Haplotypes of DNMT1 and DNMT3B are associated with mutagen sensitivity induced by benzo[a]pyrene diol epoxide among smokers
    Shuguang Leng
    Lung Cancer Program, Lovelace Respiratory Research Institute, 2425 Ridgecrest Drive Southeast, Albuquerque, NM 87108, USA
    Carcinogenesis 29:1380-5. 2008
    ..004). The association between sequence variants of DNMT1 and 3B and mutagen sensitivity induced by BPDE supports the involvement of these DNMTs in protecting the cell from DNA damage...
  84. pmc Double-strand break damage and associated DNA repair genes predispose smokers to gene methylation
    Shuguang Leng
    Lung Cancer Program, Lovelace Respiratory Research Institute, Albuquerque, NM 87108, USA
    Cancer Res 68:3049-56. 2008
    ....
  85. ncbi request reprint Quality of life following localized prostate cancer treated initially with androgen deprivation therapy or no therapy
    Arnold L Potosky
    Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, MD
    J Natl Cancer Inst 94:430-7. 2002
    ..Treatment patterns and quality-of-life outcomes have not been previously reported for a population-based sample of such men...
  86. pmc Associations between the CYP17, CYPIB1, COMT and SHBG polymorphisms and serum sex hormones in post-menopausal breast cancer survivors
    Page E Abrahamson
    Cancer Prevention Program, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave N, M4 B402, Seattle, WA, 98109 1024, USA
    Breast Cancer Res Treat 105:45-54. 2007
    ..These results provide little evidence that the CYP17, CYP1B1, and COMT polymorphisms are associated with different sex hormone levels in post-menopausal breast cancer survivors...
  87. ncbi request reprint Is alcohol intake associated with breast cancer in Hispanic women? The New Mexico Women's Health Study
    Kathy B Baumgartner
    Department of Internal Medicine, Epidemiology and Cancer Control, New Mexico Tumor Registry, Cancer Research and Treatment Center, University of New Mexico Health Sciences Center, Albuquerque, New Mexico 87131, USA
    Ethn Dis 12:460-9. 2002
    ..The alcohol/breast cancer association was investigated in a New Mexico (NM) statewide bi-ethnic study...