Sean E Gill

Summary

Affiliation: University of Washington
Country: USA

Publications

  1. pmc Metalloproteinases and their inhibitors: regulators of wound healing
    Sean E Gill
    Center for Lung Biology, University of Washington, 815 Mercer Street, Seattle, WA 98109, USA
    Int J Biochem Cell Biol 40:1334-47. 2008
  2. pmc Tissue inhibitor of metalloproteinases 3 regulates resolution of inflammation following acute lung injury
    Sean E Gill
    Center for Lung Biology, University of Washington, 815 Mercer Street, Seattle, WA 98109, USA
    Am J Pathol 176:64-73. 2010
  3. doi request reprint Tissue inhibitor of metalloproteinases-3 moderates the proinflammatory status of macrophages
    Sean E Gill
    1 Center for Lung Biology, University of Washington, Seattle, Washington
    Am J Respir Cell Mol Biol 49:768-77. 2013
  4. pmc The glutathione synthesis gene Gclm modulates amphiphilic polymer-coated CdSe/ZnS quantum dot-induced lung inflammation in mice
    Lisa A McConnachie
    Department of Environmental and Occupational Health Sciences, University of Washington, Seattle, Washington, United States of America
    PLoS ONE 8:e64165. 2013
  5. pmc Lipopolysaccharide-induced lung injury is independent of serum vitamin D concentration
    Lindy S Klaff
    Center for Lung Biology, Department of Medicine, University of Washington, Seattle, WA, USA
    PLoS ONE 7:e49076. 2012
  6. doi request reprint Pulmonary macrophage subpopulations in the induction and resolution of acute lung injury
    Laura K Johnston
    Center for Lung Biology, University of Washington, 815 Mercer Street, Seattle, WA 98109, USA
    Am J Respir Cell Mol Biol 47:417-26. 2012
  7. pmc Heterozygosity in the glutathione synthesis gene Gclm increases sensitivity to diesel exhaust particulate induced lung inflammation in mice
    Chad S Weldy
    Department of Environmental and Occupational Health, University of Washington, Seattle, WA 98195, USA
    Inhal Toxicol 23:724-35. 2011
  8. doi request reprint Mouse models of MMP and TIMP function
    Sean E Gill
    Center for Lung Biology, University of Washington School of Medicine, Seattle, WA, USA
    Methods Mol Biol 622:31-52. 2010
  9. pmc Fas-deficient mice have impaired alveolar neutrophil recruitment and decreased expression of anti-KC autoantibody:KC complexes in a model of acute lung injury
    Sucheol Gil
    The Center for Lung Biology, Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of Washington, 850 Republican Street, Box 351082, Seattle, WA 98109, USA
    Respir Res 13:91. 2012
  10. pmc Pericyte TIMP3 and ADAMTS1 modulate vascular stability after kidney injury
    Claudia Schrimpf
    Renal Division, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    J Am Soc Nephrol 23:868-83. 2012

Collaborators

Detail Information

Publications12

  1. pmc Metalloproteinases and their inhibitors: regulators of wound healing
    Sean E Gill
    Center for Lung Biology, University of Washington, 815 Mercer Street, Seattle, WA 98109, USA
    Int J Biochem Cell Biol 40:1334-47. 2008
    ..In this review, we discuss what is currently known about the function of MMPs in wound healing and will provide suggestions for future research directions...
  2. pmc Tissue inhibitor of metalloproteinases 3 regulates resolution of inflammation following acute lung injury
    Sean E Gill
    Center for Lung Biology, University of Washington, 815 Mercer Street, Seattle, WA 98109, USA
    Am J Pathol 176:64-73. 2010
    ....
  3. doi request reprint Tissue inhibitor of metalloproteinases-3 moderates the proinflammatory status of macrophages
    Sean E Gill
    1 Center for Lung Biology, University of Washington, Seattle, Washington
    Am J Respir Cell Mol Biol 49:768-77. 2013
    ..Collectively, these findings indicate that TIMP-3 functions to moderate the differentiation of macrophages into proinflammatory (M1) cells...
  4. pmc The glutathione synthesis gene Gclm modulates amphiphilic polymer-coated CdSe/ZnS quantum dot-induced lung inflammation in mice
    Lisa A McConnachie
    Department of Environmental and Occupational Health Sciences, University of Washington, Seattle, Washington, United States of America
    PLoS ONE 8:e64165. 2013
    ..Because there is a common polymorphism in humans that influences GCLM expression, these findings imply that humans with reduced GSH synthesis capabilities may be more susceptible to the pro-inflammatory effects of QDs...
  5. pmc Lipopolysaccharide-induced lung injury is independent of serum vitamin D concentration
    Lindy S Klaff
    Center for Lung Biology, Department of Medicine, University of Washington, Seattle, WA, USA
    PLoS ONE 7:e49076. 2012
    ..Vitamin D deficiency modestly impairs neutrophil chemotaxis; however, it does not affect lung injury or its resolution in an LPS model of acute lung injury...
  6. doi request reprint Pulmonary macrophage subpopulations in the induction and resolution of acute lung injury
    Laura K Johnston
    Center for Lung Biology, University of Washington, 815 Mercer Street, Seattle, WA 98109, USA
    Am J Respir Cell Mol Biol 47:417-26. 2012
    ..Alterations in the balance and function of these subpopulations could lead to nonresolving acute lung injury...
  7. pmc Heterozygosity in the glutathione synthesis gene Gclm increases sensitivity to diesel exhaust particulate induced lung inflammation in mice
    Chad S Weldy
    Department of Environmental and Occupational Health, University of Washington, Seattle, WA 98195, USA
    Inhal Toxicol 23:724-35. 2011
    ..In humans, relatively common genetic polymorphisms in both the catalytic (Gclc) and modifier (Gclm) subunits of GCL have been associated with increased risk for lung and cardiovascular diseases...
  8. doi request reprint Mouse models of MMP and TIMP function
    Sean E Gill
    Center for Lung Biology, University of Washington School of Medicine, Seattle, WA, USA
    Methods Mol Biol 622:31-52. 2010
    ..In this chapter, we discuss the phenotypes of some MMP-deficient and TIMP-null mice and strategies and pitfalls in targeted mutagenesis...
  9. pmc Fas-deficient mice have impaired alveolar neutrophil recruitment and decreased expression of anti-KC autoantibody:KC complexes in a model of acute lung injury
    Sucheol Gil
    The Center for Lung Biology, Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of Washington, 850 Republican Street, Box 351082, Seattle, WA 98109, USA
    Respir Res 13:91. 2012
    ..In this study we test the hypothesis that a functioning Fas/FasL system is required for the development of lung injury in mechanically ventilated mice...
  10. pmc Pericyte TIMP3 and ADAMTS1 modulate vascular stability after kidney injury
    Claudia Schrimpf
    Renal Division, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    J Am Soc Nephrol 23:868-83. 2012
    ....
  11. doi request reprint Kinetics of chemokine-glycosaminoglycan interactions control neutrophil migration into the airspaces of the lungs
    Yoshi Tanino
    Veterans Affairs Puget Sound Medical Center, Seattle, WA 98108, USA
    J Immunol 184:2677-85. 2010
    ..Thus, different types of chemokine gradients may form during an inflammatory response. This suggests a new model, whereby GAGs control the spatiotemporal formation of chemokine gradients and neutrophil migration in tissue...
  12. ncbi request reprint Expression analysis of the entire MMP and TIMP gene families during mouse tissue development
    Robert K Nuttall
    School of Biological Sciences, University of East Anglia, Norwich NR4 7TJ, UK
    FEBS Lett 563:129-34. 2004
    ....