S Giguere

Summary

Affiliation: University of Florida
Country: USA

Publications

  1. ncbi request reprint Equine immunity to bacteria
    S Giguere
    Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, USA
    Vet Clin North Am Equine Pract 16:29-47, v-iv. 2000
  2. ncbi request reprint Cardiac output measurement by partial carbon dioxide rebreathing, 2-dimensional echocardiography, and lithium-dilution method in anesthetized neonatal foals
    Steeve Giguere
    Departments of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL, USA
    J Vet Intern Med 19:737-43. 2005
  3. ncbi request reprint Accuracy of indirect measurement of blood pressure in neonatal foals
    Steeve Giguere
    Department of Large Animal Clinical Sciences, College of Veterinary Medicine University of Florida, Gainesville, FL 32610, USA
    J Vet Intern Med 19:571-6. 2005
  4. ncbi request reprint Immunologic disorders in neonatal foals
    Steeve Giguere
    Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, PO Box 100136, Southwest 16th Avenue, Gainesville, FL 32610, USA
    Vet Clin North Am Equine Pract 21:241-72, v. 2005
  5. ncbi request reprint Retrospective comparison of azithromycin, clarithromycin, and erythromycin for the treatment of foals with Rhodococcus equi pneumonia
    Steeve Giguere
    Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL 32610, USA
    J Vet Intern Med 18:568-73. 2004
  6. pmc Performance of five serological assays for diagnosis of Rhodococcus equi pneumonia in foals
    Steeve Giguere
    Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, Florida 32610, USA
    Clin Diagn Lab Immunol 10:241-5. 2003
  7. ncbi request reprint Cytokine induction in pulmonary airways of horses with heaves and effect of therapy with inhaled fluticasone propionate
    Steeve Giguere
    Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, P O Box 100136, Gainesville, FL 32610, USA
    Vet Immunol Immunopathol 85:147-58. 2002
  8. doi request reprint Retrospective comparison of caffeine and doxapram for the treatment of hypercapnia in foals with hypoxic-ischemic encephalopathy
    S Giguere
    Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL 32610, USA
    J Vet Intern Med 22:401-5. 2008
  9. ncbi request reprint Disposition of oral clarithromycin in foals
    S Jacks
    Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL 32610, USA
    J Vet Pharmacol Ther 25:359-62. 2002
  10. ncbi request reprint Pulmonary disposition of tilmicosin in foals and in vitro activity against Rhodococcus equi and other common equine bacterial pathogens
    A Womble
    Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL 32610, USA
    J Vet Pharmacol Ther 29:561-8. 2006

Collaborators

Detail Information

Publications29

  1. ncbi request reprint Equine immunity to bacteria
    S Giguere
    Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, USA
    Vet Clin North Am Equine Pract 16:29-47, v-iv. 2000
    ..This article summarizes the current state of knowledge on innate and adaptive immunity to bacterial pathogens and reviews various ways in which some bacteria have evolved in order to evade components of the host response...
  2. ncbi request reprint Cardiac output measurement by partial carbon dioxide rebreathing, 2-dimensional echocardiography, and lithium-dilution method in anesthetized neonatal foals
    Steeve Giguere
    Departments of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL, USA
    J Vet Intern Med 19:737-43. 2005
    ..Volumetric echocardiography using the Bullet method provides an accurate and noninvasive estimate of CO in anesthetized neonatal foals and warrants investigation in critically ill conscious foals...
  3. ncbi request reprint Accuracy of indirect measurement of blood pressure in neonatal foals
    Steeve Giguere
    Department of Large Animal Clinical Sciences, College of Veterinary Medicine University of Florida, Gainesville, FL 32610, USA
    J Vet Intern Med 19:571-6. 2005
    ..47. Indirect oscillometry with a cuff placed over the coccygeal artery or dorsal metatarsal artery is an acceptable method for measuring MAP in foals. Blood pressure does not correlate well with cardiac output in anesthetized foals...
  4. ncbi request reprint Immunologic disorders in neonatal foals
    Steeve Giguere
    Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, PO Box 100136, Southwest 16th Avenue, Gainesville, FL 32610, USA
    Vet Clin North Am Equine Pract 21:241-72, v. 2005
    ..This article summarizes the current understanding of the equine fetal and neonatal immune system and reviews common immunodeficiency disorders as well as disorders resulting from allogenic incompatibilities...
  5. ncbi request reprint Retrospective comparison of azithromycin, clarithromycin, and erythromycin for the treatment of foals with Rhodococcus equi pneumonia
    Steeve Giguere
    Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL 32610, USA
    J Vet Intern Med 18:568-73. 2004
    ..The combination clarithromycin-rifampin is superior to azithromycin-rifampin or erythromycin-rifampin for the treatment of pneumonia caused by R. equi in foals in a referral population...
  6. pmc Performance of five serological assays for diagnosis of Rhodococcus equi pneumonia in foals
    Steeve Giguere
    Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, Florida 32610, USA
    Clin Diagn Lab Immunol 10:241-5. 2003
    ..We conclude that current serological assays do not differentiate between diseased and clinically healthy foals...
  7. ncbi request reprint Cytokine induction in pulmonary airways of horses with heaves and effect of therapy with inhaled fluticasone propionate
    Steeve Giguere
    Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, P O Box 100136, Gainesville, FL 32610, USA
    Vet Immunol Immunopathol 85:147-58. 2002
    ..These results demonstrate the clinical efficacy of inhaled fluticasone propionate for the treatment of heaves and suggest a role for cytokines in the development of lower airway inflammation in heaves-susceptible horses...
  8. doi request reprint Retrospective comparison of caffeine and doxapram for the treatment of hypercapnia in foals with hypoxic-ischemic encephalopathy
    S Giguere
    Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL 32610, USA
    J Vet Intern Med 22:401-5. 2008
    ..Despite a lack of data regarding their efficacy, both caffeine and doxapram have been recommended for treatment of hypercapnia in equine neonates with central nervous system damage...
  9. ncbi request reprint Disposition of oral clarithromycin in foals
    S Jacks
    Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL 32610, USA
    J Vet Pharmacol Ther 25:359-62. 2002
    ..Based on the pharmacokinetic parameters, the MIC90 of R. equi isolates, and predicted steady state concentrations, an oral dose of 7.5 mg/kg given every 12 hours would appear appropriate for the treatment of R. equi infections in foals...
  10. ncbi request reprint Pulmonary disposition of tilmicosin in foals and in vitro activity against Rhodococcus equi and other common equine bacterial pathogens
    A Womble
    Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL 32610, USA
    J Vet Pharmacol Ther 29:561-8. 2006
    ..Tilmicosin was active in vitro against most streptococci, Staphylococcus spp., Actinobacillus spp., and Pasteurella spp. The drug was not active against Enterococcus spp., Pseudomonas spp., and Enterobacteriaceae...
  11. doi request reprint Disposition of oral telithromycin in foals and in vitro activity of the drug against macrolide-susceptible and macrolide-resistant Rhodococcus equi isolates
    L H Javsicas
    Department of Large Animal Medicine, College of Veterinary Medicine, University of Georgia, Athens, GA 30602, USA
    J Vet Pharmacol Ther 33:383-8. 2010
    ..The MIC of telithromycin for macrolide-resistant isolates (MIC(50)=4.0 microg/mL) was significantly lower than that of clarithromycin (MIC(50)=24.0 microg/mL), azithromycin (MIC(50)=256 microg/mL) and erythromycin (MIC(50)=24 microg/mL)...
  12. doi request reprint Disposition of desfuroylceftiofur acetamide in serum, placental tissue, fetal fluids, and fetal tissues after administration of ceftiofur crystalline free acid (CCFA) to pony mares with placentitis
    M L Macpherson
    Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL 32610, USA
    J Vet Pharmacol Ther 36:59-67. 2013
    ..Treatment did not appear to improve foal survival (CEFT: 0/3; COMBO: 2/6; UNTREAT: 2/3). Bacteria were recovered from the uterus of most mares postpartum and from blood cultures of most foals regardless of treatment...
  13. ncbi request reprint Relationship between infection, inflammation and premature parturition in mares with experimentally induced placentitis
    M M LeBlanc
    Department of Large Animal Clinical Sciences, University of Florida, Gainesville, Florida, USA
    Equine Vet J Suppl 44:8-14. 2012
    ..By understanding how placentitis induces premature delivery, it may be possible to develop diagnostic markers and to delay premature delivery pharmacologically, thereby decreasing perinatal foal mortality...
  14. ncbi request reprint Pharmacokinetics and pharmacodynamics of pantoprazole in clinically normal neonatal foals
    C A Ryan
    Island Whirl Equine Colic Research Laboratory, Department of Large Animal Clinical Sciences, College of Veterinary Medicine, PO Box 100136, University of Florida, Gainesville, Florida 32610 0136, USA
    Equine Vet J 37:336-41. 2005
    ..Currently, only an oral preparation of omeprazole is approved for use in horses in the USA. Intravenous administration of a PPI would provide a useful therapeutic alternative for those foals in which oral medication is not feasible...
  15. ncbi request reprint Pharmacokinetics of oral doxycycline and concentrations in body fluids and bronchoalveolar cells of foals
    A Womble
    Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL, USA
    J Vet Pharmacol Ther 30:187-93. 2007
    ....
  16. ncbi request reprint Pulmonary disposition of erythromycin, azithromycin, and clarithromycin in foals
    G Suarez-Mier
    Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL 32610, USA
    J Vet Pharmacol Ther 30:109-15. 2007
    ..Peak azithromycin and clarithromycin activity was significantly higher in BAL cells, followed by PELF, and serum. In contrast, peak erythromycin activity in BAL cells was not significantly different from that of serum...
  17. doi request reprint Plasma and pulmonary disposition of ceftiofur and its metabolites after intramuscular administration of ceftiofur crystalline free acid in weanling foals
    B C Credille
    Department of Large Animal Medicine, College of Veterinary Medicine, University of Georgia, Athens, GA 30602, USA
    J Vet Pharmacol Ther 35:259-64. 2012
    ..2 μg/mL for at least 4 days and would be expected to be an effective treatment for pneumonia caused by Streptococcus equi subsp. zooepidemicus at doses similar to the adult label...
  18. doi request reprint The effects of deferoxamine mesylate on iron elimination after blood transfusion in neonatal foals
    J R Elfenbein
    Department of Large Animal Medicine, College of Veterinary Medicine, University of Georgia, Athens, GA 32602, USA
    J Vet Intern Med 24:1475-82. 2010
    ..Hepatic failure is one of the more common complications in foals requiring blood transfusion to treat neonatal isoerythrolysis. Iron intoxication is likely the cause of hepatic injury...
  19. ncbi request reprint Lamellar pro-inflammatory cytokine expression patterns in laminitis at the developmental stage and at the onset of lameness: innate vs. adaptive immune response
    J K Belknap
    Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Ohio State University, Columbus, Ohio 43210, USA
    Equine Vet J 39:42-7. 2007
    ..Characterisation of the type of immune response (i.e. innate vs. adaptive) is essential in order to develop therapeutic strategies to counteract these deleterious events...
  20. doi request reprint Effect of age on the pharmacokinetics of a single daily dose of gentamicin sulfate in healthy foals
    A J Burton
    Department of Large Animal Medicine, College of Veterinary Medicine, University of Georgia, Athens, Georgia, USA
    Equine Vet J 45:507-11. 2013
    ..6 mg/kg bwt q. 24 h for gentamicin is too low and a dose of 12 mg/kg bwt has been proposed. The pharmacokinetics of this dosage in foals and the ages at which this higher dose should be used have not previously been investigated...
  21. doi request reprint Treatment efficacy of trimethoprim sulfamethoxazole, pentoxifylline and altrenogest in experimentally induced equine placentitis
    C S Bailey
    University of Florida, Dept of LACS, College of Veterinary Medicine, PO Box 100136, Gainesville, FL 32610, USA
    Theriogenology 74:402-12. 2010
    ..The authors inferred that administration of trimethoprim sulfamethoxazole, pentoxifylline and altrenogest may improve the viability of foals from mares with experimentally induced placentitis...
  22. ncbi request reprint Increased pulmonary activation of nuclear factor-kappaB (NF-kappaB) in foals inoculated with Rhodococcus equi is associated with increased expression of inflammatory cytokines
    E W Uhl
    Department of Pathobiology, College of Veterinary Medicine, University of Florida, Gainesville 32610 0145, USA
    Vet Pathol 39:132-6. 2002
    ..Southwestern histochemistry revealed activated NF-kappaB in multinucleated giant cells that often contained bacteria. These results indicate that the cytokine response to R. equi is at least partially mediated by NF-kappaB activation...
  23. doi request reprint Doppler and volumetric echocardiographic methods for cardiac output measurement in standing adult horses
    E McConachie
    Department of Large Animal Medicine, College of Veterinary Medicine, University of Georgia, Athens, GA 30602, USA
    J Vet Intern Med 27:324-30. 2013
    ..Cardiac output (CO) is not routinely measured in critically ill adult horses because of invasiveness of currently validated methods. Noninvasive CO monitoring would complement clinical assessment of hemodynamic status in adult horses...
  24. doi request reprint Infectious agents detected in the feces of diarrheic foals: a retrospective study of 233 cases (2003-2008)
    J Frederick
    Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL, USA
    J Vet Intern Med 23:1254-60. 2009
    ..Diarrhea is common in foals but there are no studies investigating the relative prevalence of common infectious agents in a population of hospitalized diarrheic foals...
  25. doi request reprint Effect of age, feeding, and omeprazole administration on gastric tonometry in healthy neonatal foals
    L C Sanchez
    Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL 32610 0136, USA
    J Vet Intern Med 22:406-10. 2008
    ..Gastric tonometry is commonly used in humans as an assessment of intestinal mucosal perfusion. Values in healthy foals are currently unknown...
  26. doi request reprint Factors associated with outcome in foals with neonatal isoerythrolysis (72 cases, 1988-2003)
    A C Polkes
    Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL 32610, USA
    J Vet Intern Med 22:1216-22. 2008
    ..Neonatal foals with isoerythrolysis (NI) often die, but the risk factors for death have not been identified...
  27. doi request reprint Pharmacokinetics of intravenous ceftiofur sodium and concentration in body fluids of foals
    S Meyer
    Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL 32610, USA
    J Vet Pharmacol Ther 32:309-16. 2009
    ..5 microg/mL. Intravenous administration of ceftiofur sodium at the rate of 5 mg/kg every 12 h would provide sufficient coverage for the treatment of susceptible bacterial isolates...
  28. ncbi request reprint Effect of a constant rate infusion of lidocaine on the quality of recovery from sevoflurane or isoflurane general anaesthesia in horses
    A Valverde
    Department of Large Animal Clinical Sciences, University of Florida, Gainesville, Florida, USA
    Equine Vet J 37:559-64. 2005
    ..Lidocaine constant rate infusions (CRIs) are common as an intraoperative adjunct to general anaesthesia, but their influence on quality of recovery has not been thoroughly determined...
  29. ncbi request reprint Relationship between infection, inflammation and premature parturition in mares with experimentally induced placentitis
    M M LeBlanc
    Department of Large Animal Clinical Sciences, University of Florida, Gainesville, Florida, USA
    Equine Vet J 44:8-14. 2012
    ..By understanding how placentitis induces premature delivery, it may be possible to develop diagnostic markers and to delay premature delivery pharmacologically, thereby decreasing perinatal foal mortality...