W Brian Gibler

Summary

Affiliation: University of Cincinnati
Country: USA

Publications

  1. ncbi A randomized trial of the effects of early cardiac serum marker availability on reperfusion therapy in patients with acute myocardial infarction: the serial markers, acute myocardial infarction and rapid treatment trial (SMARTT)
    W B Gibler
    University of Cincinnati College of Medicine, Ohio 45267 0769, USA
    J Am Coll Cardiol 36:1500-6. 2000
  2. ncbi Persistence of delays in presentation and treatment for patients with acute myocardial infarction: The GUSTO-I and GUSTO-III experience
    W Brian Gibler
    Department of Emergency Medicine, University of Cincinnati, Cincinnati OH, USA
    Ann Emerg Med 39:123-30. 2002
  3. ncbi The obesity paradox in non-ST-segment elevation acute coronary syndromes: results from the Can Rapid risk stratification of Unstable angina patients Suppress ADverse outcomes with Early implementation of the American College of Cardiology/American Heart A
    Deborah B Diercks
    Department of Emergency Medicine, University of California, Davis, School of Medicine, Sacramento, CA, USA
    Am Heart J 152:140-8. 2006
  4. ncbi The elder patient with suspected acute coronary syndromes in the emergency department
    Jin H Han
    Department of Emergency Medicine, Vanderbilt University Medical Center, Nashville, TN, USA
    Acad Emerg Med 14:732-9. 2007
  5. ncbi The role of cardiac risk factor burden in diagnosing acute coronary syndromes in the emergency department setting
    Jin H Han
    Vanderbilt University Medical Center, Department of Emergency Medicine, Nashville, TN 37232 4700, USA
    Ann Emerg Med 49:145-52, 152.e1. 2007
  6. ncbi Performance of a population-based cardiac risk stratification tool in Asian patients with chest pain
    Chadwick D Miller
    Department of Emergency Medicine, Wake Forest University Health Sciences, Medical Center Boulevard, Winston Salem, NC 27157 1089, USA
    Acad Emerg Med 12:423-30. 2005
  7. ncbi The Internet Tracking Registry of Acute Coronary Syndromes (i*trACS): a multicenter registry of patients with suspicion of acute coronary syndromes reported using the standardized reporting guidelines for emergency department chest pain studies
    Christopher J Lindsell
    Department of Emergency Medicine, University of Cincinnati Medical Center, Cincinnati, OH 45267 0769, USA
    Ann Emerg Med 48:666-77, 677.e1-9. 2006
  8. ncbi Chronic kidney disease in patients with non-ST-segment elevation acute coronary syndromes
    Jin H Han
    Department of Emergency Medicine, University of Cincinnati School of Medicine, Cincinnati, Ohio, USA
    Am J Med 119:248-54. 2006
  9. ncbi Discordant cardiac biomarkers: frequency and outcomes in emergency department patients with chest pain
    Alan B Storrow
    Department of Emergency Medicine, Vanderbilt University Medical Center, Nashville, TN 37232 4700, USA
    Ann Emerg Med 48:660-5. 2006
  10. ncbi Predictors of 30-day cardiovascular events in patients with prior percutaneous coronary intervention or coronary artery bypass grafting
    Emily C Esposito
    Department of Emergency Medicine, University of Pennsylvania, Philadelphia, USA
    Acad Emerg Med 18:613-8. 2011

Detail Information

Publications76

  1. ncbi A randomized trial of the effects of early cardiac serum marker availability on reperfusion therapy in patients with acute myocardial infarction: the serial markers, acute myocardial infarction and rapid treatment trial (SMARTT)
    W B Gibler
    University of Cincinnati College of Medicine, Ohio 45267 0769, USA
    J Am Coll Cardiol 36:1500-6. 2000
    ..The purpose of this study was to assess whether the immediate availability of serum markers would increase the appropriate use of thrombolytic therapy...
  2. ncbi Persistence of delays in presentation and treatment for patients with acute myocardial infarction: The GUSTO-I and GUSTO-III experience
    W Brian Gibler
    Department of Emergency Medicine, University of Cincinnati, Cincinnati OH, USA
    Ann Emerg Med 39:123-30. 2002
    ....
  3. ncbi The obesity paradox in non-ST-segment elevation acute coronary syndromes: results from the Can Rapid risk stratification of Unstable angina patients Suppress ADverse outcomes with Early implementation of the American College of Cardiology/American Heart A
    Deborah B Diercks
    Department of Emergency Medicine, University of California, Davis, School of Medicine, Sacramento, CA, USA
    Am Heart J 152:140-8. 2006
    ..Although obesity is a known risk factor for coronary artery disease, its impact on the presentation, treatment, and outcome of patients with acute coronary syndromes (ACS) has not been well studied...
  4. ncbi The elder patient with suspected acute coronary syndromes in the emergency department
    Jin H Han
    Department of Emergency Medicine, Vanderbilt University Medical Center, Nashville, TN, USA
    Acad Emerg Med 14:732-9. 2007
    ..To describe the evaluation and outcomes of elder patients with suspected acute coronary syndromes (ACS) presenting to the emergency department (ED)...
  5. ncbi The role of cardiac risk factor burden in diagnosing acute coronary syndromes in the emergency department setting
    Jin H Han
    Vanderbilt University Medical Center, Department of Emergency Medicine, Nashville, TN 37232 4700, USA
    Ann Emerg Med 49:145-52, 152.e1. 2007
    ..We seek to determine whether cardiac risk factor burden (defined as the number of conventional cardiac risk factors present) is useful for the diagnosis of acute coronary syndromes in the emergency department (ED) setting...
  6. ncbi Performance of a population-based cardiac risk stratification tool in Asian patients with chest pain
    Chadwick D Miller
    Department of Emergency Medicine, Wake Forest University Health Sciences, Medical Center Boulevard, Winston Salem, NC 27157 1089, USA
    Acad Emerg Med 12:423-30. 2005
    ..Their validity in single-race populations has not been tested. The authors sought to compare the performance of a risk stratification tool between a mixed-race U.S. patient population and an Asian patient population...
  7. ncbi The Internet Tracking Registry of Acute Coronary Syndromes (i*trACS): a multicenter registry of patients with suspicion of acute coronary syndromes reported using the standardized reporting guidelines for emergency department chest pain studies
    Christopher J Lindsell
    Department of Emergency Medicine, University of Cincinnati Medical Center, Cincinnati, OH 45267 0769, USA
    Ann Emerg Med 48:666-77, 677.e1-9. 2006
    ..We describe the methods for data collection and the ED population enrolled in a multicenter registry of patients with chest pain...
  8. ncbi Chronic kidney disease in patients with non-ST-segment elevation acute coronary syndromes
    Jin H Han
    Department of Emergency Medicine, University of Cincinnati School of Medicine, Cincinnati, Ohio, USA
    Am J Med 119:248-54. 2006
    ..We examined the treatment and outcomes of patients with both non-ST-segment elevation acute coronary syndromes and moderate to severe chronic kidney disease...
  9. ncbi Discordant cardiac biomarkers: frequency and outcomes in emergency department patients with chest pain
    Alan B Storrow
    Department of Emergency Medicine, Vanderbilt University Medical Center, Nashville, TN 37232 4700, USA
    Ann Emerg Med 48:660-5. 2006
    ....
  10. ncbi Predictors of 30-day cardiovascular events in patients with prior percutaneous coronary intervention or coronary artery bypass grafting
    Emily C Esposito
    Department of Emergency Medicine, University of Pennsylvania, Philadelphia, USA
    Acad Emerg Med 18:613-8. 2011
    ....
  11. ncbi Early treatment for non-ST-segment elevation acute coronary syndrome is associated with appropriate discharge care
    Gregory J Fermann
    Department of Emergency Medicine, University of Cincinnati, Cincinnati, Ohio 45267 0769, USA
    Clin Cardiol 32:519-25. 2009
    ..Acute treatment is associated with improved in-hospital outcomes for patients with non-ST-segment elevation acute coronary syndrome (NSTE ACS)...
  12. ncbi Early glycoprotein IIb/IIIa inhibitor use for non-ST-segment elevation acute coronary syndrome: patient selection and associated treatment patterns
    James W Hoekstra
    Department of Emergency Medicine, Wake Forest University Health Sciences, Medical Center Boulevard, Winston Salem, NC 27157, USA
    Acad Emerg Med 12:431-8. 2005
    ....
  13. ncbi Ground emergency medical services requests for helicopter transfer of ST-segment elevation myocardial infarction patients decrease medical contact to balloon times in rural and suburban settings
    Jason T McMullan
    Department of Emergency Medicine, University of Cincinnati, Cincinnati, OH, USA
    Acad Emerg Med 19:153-60. 2012
    ..This investigation models potential time savings of ground EMS requests for helicopter EMS (HEMS) transport of a STEMI patient directly to a PCI center, rather than usual transport to a local hospital with subsequent transfer...
  14. ncbi Is the initial diagnostic impression of "noncardiac chest pain" adequate to exclude cardiac disease?
    Chadwick D Miller
    Department of Emergency Medicine, Wake Forest University, Winston Salem, NC 27157 1089, USA
    Ann Emerg Med 44:565-74. 2004
    ..In patients presenting to the emergency department (ED) with an initial diagnostic impression of noncardiac chest pain, we determine the 30-day incidence of adverse cardiac events and characteristics associated with those events...
  15. ncbi Treatment disparities in the care of patients with and without diabetes presenting with non-ST-segment elevation acute coronary syndromes
    Gerard X Brogan
    Department of Emergency Medicine, New York University School of Medicine North Shore Long Island Jewish Health System, Plainview, New York 11803, USA
    Diabetes Care 29:9-14. 2006
    ..The objective of this study was to characterize treatment patterns among patients with diabetes presenting with non-ST-segment elevation (NSTE) acute coronary syndromes (ACSs)...
  16. ncbi Utilization and impact of pre-hospital electrocardiograms for patients with acute ST-segment elevation myocardial infarction: data from the NCDR (National Cardiovascular Data Registry) ACTION (Acute Coronary Treatment and Intervention Outcomes Network) Re
    Deborah B Diercks
    Department of Emergency Medicine, University of California, Davis Medical Center, Sacramento, CA 95661, USA
    J Am Coll Cardiol 53:161-6. 2009
    ..This study sought to determine the association of pre-hospital electrocardiograms (ECGs) and the timing of reperfusion therapy for patients with ST-segment elevation myocardial infarction (STEMI)...
  17. ncbi Gender disparities in the diagnosis and treatment of non-ST-segment elevation acute coronary syndromes: large-scale observations from the CRUSADE (Can Rapid Risk Stratification of Unstable Angina Patients Suppress Adverse Outcomes With Early Implementatio
    Andra L Blomkalns
    Department of Emergency Medicine, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0769, USA
    J Am Coll Cardiol 45:832-7. 2005
    ..We hypothesized that significant disparities in gender exist in the management of patients with non-ST-segment elevation (NSTE) acute coronary syndromes (ACS)...
  18. ncbi Practical implementation of the Guidelines for Unstable Angina/Non-ST-Segment Elevation Myocardial Infarction in the emergency department
    W Brian Gibler
    University of Cincinnati College of Medicine, USA
    Ann Emerg Med 46:185-97. 2005
    ..Despite publication of the guidelines several years ago, many patients with UA/NSTEMI still do not receive guidelines-indicated therapy...
  19. ncbi Insurance status and the treatment of myocardial infarction at academic centers
    Brian C Hiestand
    Department of Emergency Medicine, The Ohio State University, 149 Means Hall, 1654 Upham Drive, Columbus, OH 43210 1270, USA
    Acad Emerg Med 11:343-8. 2004
    ..Numerous studies have documented treatment disparities in patients with acute coronary syndromes based on race and gender. Other causes for treatment disparities may exist...
  20. ncbi Guideline implementation research: exploring the gap between evidence and practice in the CRUSADE Quality Improvement Initiative
    Andra L Blomkalns
    Department of Emergency Medicine, University of Cincinnati College of Medicine, Cincinnati, OH, USA
    Acad Emerg Med 14:949-54. 2007
    ....
  21. ncbi Standardized reporting guidelines for studies evaluating risk stratification of ED patients with potential acute coronary syndromes
    Judd E Hollander
    Department of Emergency Medicine, Ground Floor, Ravdin Building, Hospital of the University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19104-4293, USA
    Acad Emerg Med 11:1331-40. 2004
  22. ncbi Chest pain unit concept: rationale and diagnostic strategies
    Andra L Blomkalns
    Department of Emergency Medicine, University of Cincinnati College of Medicine, OH 45267 0769, USA
    Cardiol Clin 23:411-21, v. 2005
    ..This evaluation is required to appropriately determine if a patient is safe to be discharged home with outpatient follow-up versus requiring admission to the hospital for monitoring and further testing...
  23. ncbi Evaluation of dyslipidemia in the emergency department: impact of cholesterol testing on subsequent therapy
    Andra L Blomkalns
    Department of Emergency Medicine, University of Cincinnati College of Medicine, Cincinnati, OH, USA
    Am Heart J 152:1182-6. 2006
    ..Dyslipidemia is not routinely evaluated in emergency department (ED) patients. We hypothesized that many ED patients would qualify for lipid therapy and that methods of follow-up for patients would not achieve adequate treatment goals...
  24. ncbi Emergency department observation of heart failure: preliminary analysis of safety and cost
    Alan B Storrow
    Department of Emergency Medicine, University of Cincinnati, Cincinnati, OH 45267 0769, USA
    Congest Heart Fail 11:68-72. 2005
    ..These findings need to be further evaluated in a randomized clinical trial...
  25. ncbi Evidence-based emergency medicine. Creating a system to facilitate translation of evidence into standardized clinical practice: a preliminary report
    Stewart W Wright
    Department of Emergency Medicine, University of Cincinnati, Cincinnati, OH 45267 0769, USA
    Ann Emerg Med 51:80-6, 86.e1-8. 2008
    ..This article reviews the construction, ongoing development, and initial impact of such a system at a large, urban, university teaching hospital and at 2 affiliated community hospitals...
  26. ncbi Reperfusion is delayed beyond guideline recommendations in patients requiring interhospital helicopter transfer for treatment of ST-segment elevation myocardial infarction
    Jason T McMullan
    Department of Emergency Medicine, University of Cincinnati, Cincinnati, OH, USA
    Ann Emerg Med 57:213-220.e1. 2011
    ....
  27. ncbi A multicenter randomized controlled trial comparing central laboratory and point-of-care cardiac marker testing strategies: the Disposition Impacted by Serial Point of Care Markers in Acute Coronary Syndromes (DISPO-ACS) trial
    Richard J Ryan
    Department of Emergency Medicine, University of Cincinnati, Cincinnati, OH 45267, USA
    Ann Emerg Med 53:321-8. 2009
    ..We hypothesized that point-of-care testing decreases length of stay in patients being evaluated for acute coronary syndromes in the emergency department (ED)...
  28. ncbi Resting radionuclide myocardial perfusion imaging in a chest pain center including an overnight delayed image acquisition protocol
    Michael W Schaeffer
    Division of Cardiovascular Medicine, University of Cincinnati College of Medicine, 231 Albert Sabin Way, Cincinnati, OH 45267, USA
    J Nucl Med Technol 35:242-5. 2007
    ....
  29. ncbi The impact of race on the acute management of chest pain
    Arvind Venkat
    Department of Emergency Medicine, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA
    Acad Emerg Med 10:1199-208. 2003
    ..40 to 0.68 and OR, 0.68; 95% CI = 0.47 to 0.99). CONCLUSIONS: Racial disparities in acute chest pain management extend beyond cardiac catheterization. Poor compliance with recommended treatments for ACS may be an explanation...
  30. ncbi Evaluation of chest pain and heart failure in the emergency department: impact of multimarker strategies and B-type natriuretic peptide
    W Brian Gibler
    Department of Emergency Medicine, University of Cincinnati, Cincinnati, Ohio, USA
    Rev Cardiovasc Med 4:S47-55. 2003
    ..This article reviews the use of cardiac biomarkers in the emergency department to evaluate acute coronary syndrome and congestive heart failure...
  31. ncbi Performance of a body surface mapping system using emergency physician real-time interpretation
    Gregory J Fermann
    Department of Emergency Medicine, University of Cincinnati, PO Box 670769, Cincinnati, OH 45267 0769, USA
    Am J Emerg Med 27:816-22. 2009
    ..We compared the performance characteristics of the 12-lead electrocardiography (ECG) with body surface mapping (BSM) in patients presenting for evaluation of symptoms suggestive of acute coronary syndromes...
  32. ncbi Can electrocardiographic criteria predict adverse cardiac events and positive cardiac markers?
    Andra L Blomkalns
    University of Cincinnati, Cincinnati, OH45267 0769, USA
    Acad Emerg Med 10:205-10. 2003
    ..The authors hypothesized that specific ECG findings, other than those previously identified in higher-risk populations, would be predictive of cardiac outcomes and positive cardiac markers...
  33. ncbi Changes in cardiac troponin T measurements are associated with adverse cardiac events in patients with chronic kidney disease
    Jin H Han
    Department of Emergency Medicine, University of Cincinnati Medical Center, Cincinnati, OH 45267 0769, USA
    Am J Emerg Med 23:468-73. 2005
    ..10 ng/mL. For in-hospital and 30-day ACE, a short-term increase in cTnT of 0.11 ng/mL had a positive likelihood ratio of 13.3 and 11.9, respectively. Long-term and short-term increases in cTnT are associated with an ACE...
  34. ncbi Development of the chest pain center: rationale, implementation, efficacy, and cost-effectiveness
    Andra L Blomkalns
    University of Cincinnati College of Medicine, Department of Emergency Medicine, Ohio 45267-0769, USA
    Prog Cardiovasc Dis 46:393-403. 2004
  35. ncbi Prospective evaluation of emergency department patients with potential coronary syndromes using initial absolute CK-MB vs. CK-MB relative index
    Otilia Capellan
    Department of Emergency Medicine, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania 19104-4283, USA
    J Emerg Med 24:361-7. 2003
    ..The optimal test depends upon the relative importance of the sensitivity or specificity for clinical decision-making in an individual patient...
  36. ncbi Residency training in emergency medicine: the challenges of the 21st century
    Annette L Williams
    Department of Emergency Medicine, University of Cincinnati, Cincinnati, OH, USA
    Keio J Med 53:203-9. 2004
    ..According to manpower studies, a great need still exists for Emergency Physicians in many United States hospitals, particularly in rural communities...
  37. ncbi Images in emergency medicine. Gonococcal conjunctivitis
    Benjamin P Donham
    University of Cincinnati, Department of Emergency Medicine, Cincinnati, OH, USA
    Ann Emerg Med 52:11, 16. 2008
  38. ncbi Acute coronary care in the elderly, part II: ST-segment-elevation myocardial infarction: a scientific statement for healthcare professionals from the American Heart Association Council on Clinical Cardiology: in collaboration with the Society of Geriatric
    Karen P Alexander
    Duke University Medical Center, USA
    Circulation 115:2570-89. 2007
    ....
  39. ncbi Pay for performance, quality of care, and outcomes in acute myocardial infarction
    Seth W Glickman
    Center for Clinical and Genetic Economics, Duke University Medical Center, Durham, NC, USA
    JAMA 297:2373-80. 2007
    ..In 2003, the Centers for Medicare & Medicaid Services (CMS) launched the largest pay-for-performance pilot project to date in the United States, including indicators for acute myocardial infarction...
  40. ncbi Acute coronary care in the elderly, part I: Non-ST-segment-elevation acute coronary syndromes: a scientific statement for healthcare professionals from the American Heart Association Council on Clinical Cardiology: in collaboration with the Society of Ger
    Karen P Alexander
    Duke University Medical Center, USA
    Circulation 115:2549-69. 2007
    ..Reasons include limited trial data to guide the care of older adults and uncertainty about benefits and risks, particularly with newer medications or invasive treatments and in the setting of advanced age or complex health status...
  41. ncbi Heart failure with preserved left ventricular systolic function among patients with non-ST-segment elevation acute coronary syndromes
    Kyla M Bennett
    Duke Clinical Research Institute, Duke University Medical Center, Durham, North Carolina
    Am J Cardiol 99:1351-6. 2007
    ..Guideline-recommended therapies and interventions are under-utilized in patients with NSTE ACS and HF, with and without preserved systolic function, compared with those without HF...
  42. ncbi Prolonged emergency department stays of non-ST-segment-elevation myocardial infarction patients are associated with worse adherence to the American College of Cardiology/American Heart Association guidelines for management and increased adverse events
    Deborah B Diercks
    University of California, Davis, School of Medicine, Sacramento, CA, USA
    Ann Emerg Med 50:489-96. 2007
    ..We hypothesized that patients with non-ST-segment-elevation myocardial infarction who have ED stays of greater than 8 hours may have lower quality of care and worse outcomes...
  43. ncbi Impact of acute beta-blocker therapy for patients with non-ST-segment elevation myocardial infarction
    Chadwick D Miller
    Wake Forest University Health Sciences, Winston Salem, NC, USA
    Am J Med 120:685-92. 2007
    ..We sought to determine the impact of acute beta-blocker therapy on outcomes in patients with NSTEMI...
  44. ncbi Changing the model of care for patients with acute coronary syndromes
    Matthew T Roe
    Duke Clinical Research Institute, Durham, NC 27715, USA
    Am Heart J 146:605-12. 2003
    ..The shifting model of care for ACS therefore suggests that quality improvement and monitoring of adherence to practice guidelines should be considered components of optimal clinical practice...
  45. ncbi The impact of for-profit hospital status on the care and outcomes of patients with non-ST-segment elevation myocardial infarction: results from the CRUSADE Initiative
    Bimal R Shah
    Duke Clinical Research Institute, Duke University Medical Center, Durham, North Carolina 27710, USA
    J Am Coll Cardiol 50:1462-8. 2007
    ..We sought to determine whether for-profit status influenced hospitals' care or outcomes among non-ST-segment elevation myocardial infarction (NSTEMI) patients...
  46. ncbi Critical pathways for management of patients with acute coronary syndromes: an assessment by the National Heart Attack Alert Program
    Christopher P Cannon
    Cardiovascular Division, Brigham and Women's Hospital, Boston, MA, USA
    Am Heart J 143:777-89. 2002
    ..Their use should improve the process and cost-effectiveness of care, but further research in this field is needed to determine whether these changes in the process of care will translate into improved clinical outcomes...
  47. ncbi Improving the care of patients with non-ST-elevation acute coronary syndromes in the emergency department: the CRUSADE initiative
    James W Hoekstra
    Ohio State University, Columbus, OH 43210, USA
    Acad Emerg Med 9:1146-55. 2002
    ..It is the intent of CRUSADE to improve patient care in the ED by tracking and encouraging compliance with evidence-based guidelines for the evaluation and management of NSTE ACS...
  48. ncbi Does chronic Chlamydia pneumoniae infection increase the risk of myocardial injury? Insights from patients with non-ST-elevation acute coronary syndromes
    Brian Y L Wong
    University of Alberta, Edmonton, Alberta, Canada
    Am Heart J 144:987-94. 2002
    ..Accordingly, we evaluated plasma samples acquired at presentation in 178 patients with ACS for a possible association between Cpn IgA titer and biochemical evidence of myocardial injury...
  49. ncbi 2-D echocardiography prediction of adverse events in ED patients with chest pain
    Swee Han Lim
    Department of Emergency Medicine, Singapore General Hospital, Republic of Singapore
    Am J Emerg Med 21:106-10. 2003
    ..Resting 2-D echo did not predict cardiac adverse events in patients with possible ACS and non-diagnostic serial 12-lead ECG and normal serial CK-MB at the end of a 9-hour evaluation...
  50. ncbi Patterns of transfer for patients with non-ST-segment elevation acute coronary syndrome from community to tertiary care hospitals
    Matthew T Roe
    Duke Clinical Research Institute, Durham, NC 27705, USA
    Am Heart J 156:185-92. 2008
    ....
  51. ncbi Comparison of 30-day outcome, resource use, and coronary artery disease severity in patients with suspected coronary artery disease with and without diabetes mellitus assigned to chest pain units
    Carlos D Sánchez
    Duke University School of Medicine and Duke Clinical Research Institute, Durham, North Carolina 27715 7969, USA
    Am J Cardiol 91:1228-30. 2003
  52. ncbi Paradoxical use of invasive cardiac procedures for patients with non-ST segment elevation myocardial infarction: an international perspective from the CRUSADE Initiative and the Canadian ACS Registries I and II
    Mohammad I Zia
    Canadian Heart Research Centre, Toronto, Canada
    Can J Cardiol 23:1073-9. 2007
    ..Practice guidelines support an early invasive strategy in patients with non-ST segment elevation acute coronary syndromes, particularly in those at higher risk...
  53. ncbi Prognostic value of isolated troponin elevation across the spectrum of chest pain syndromes
    Sunil V Rao
    Duke Clinical Research Institute, PO Box 17969, Durham, NC 27715, USA
    Am J Cardiol 91:936-40. 2003
    ..This suggests that these patients should be admitted to the hospital and monitored in either an intensive care or step-down unit...
  54. ncbi Patterns of aspirin dosing in non-ST-elevation acute coronary syndromes in the CRUSADE Quality Improvement Initiative
    Sumit Tickoo
    Bridgeport Hospital, Bridgeport, Connecticut, USA
    Am J Cardiol 99:1496-9. 2007
    ....
  55. ncbi A randomized, placebo-controlled trial of early eptifibatide for non-ST-segment elevation acute coronary syndromes
    Matthew T Roe
    Duke Clinical Research Institute, Durham, NC 27715, USA
    Am Heart J 146:993-8. 2003
    ..The acute benefits of platelet glycoprotein IIb/IIIa inhibitors for non-ST-segment elevation acute coronary syndromes (NSTE ACS) remain unclear...
  56. ncbi Impact of congestive heart failure in patients with non-ST-segment elevation acute coronary syndromes
    Matthew T Roe
    Division of Cardiology and Duke Clinical Research Institute, Duke University Medical Center, Durham, North Carolina, USA
    Am J Cardiol 97:1707-12. 2006
    ..Further study is needed to determine the causes of these treatment differences and the optimal therapeutic approach for patients with NSTE ACS and concomitant CHF...
  57. ncbi Care of non-ST-segment elevation patients: insights from the CRUSADE national quality improvement initiative
    E Magnus Ohman
    Division of Cardiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
    Am Heart J 148:S34-9. 2004
    ..These ACC/AHA guidelines are intended to help physicians make appropriate decisions when diagnosing and treating patients with NSTE ACS...
  58. ncbi Overcoming the challenges facing quality-improvement strategies for non-ST-segment elevation acute coronary syndromes
    Matthew T Roe
    Am Fam Physician 70:1868, 1874, 1876. 2004
  59. ncbi Door-to-ECG time in patients with chest pain presenting to the ED
    Deborah B Diercks
    Division of Emergency Medicine, University of California, Davis Medical Center, Sacramento, 95817, USA
    Am J Emerg Med 24:1-7. 2006
    ..To describe time to electrocardiogram (ECG) acquisition, identify factors associated with timely acquisition, and evaluate the influence of time to ECG on adverse clinical outcomes...
  60. ncbi Evolution in cardiovascular care for elderly patients with non-ST-segment elevation acute coronary syndromes: results from the CRUSADE National Quality Improvement Initiative
    Karen P Alexander
    Duke Clinical Research Institute and Division of Cardiology, Duke University Medical Center, Durham, North Carolina 27715, USA
    J Am Coll Cardiol 46:1479-87. 2005
    ..This study evaluated the impact of age on care and outcomes for non-ST-segment elevation acute coronary syndromes (NSTE ACS)...
  61. ncbi Relationship between risk stratification by cardiac troponin level and adherence to guidelines for non-ST-segment elevation acute coronary syndromes
    Matthew T Roe
    Division of Cardiology and Duke Clinical Research Institute, Duke University Medical Center, Durham, NC 27705, USA
    Arch Intern Med 165:1870-6. 2005
    ..The threshold of troponin elevation that stimulates changes in clinical decision making for patients with non-ST-segment elevation acute coronary syndromes (NSTE ACSs) has not been previously evaluated...
  62. ncbi Lipid management in patients with unstable angina pectoris and non-ST-segment elevation acute myocardial infarction (from CRUSADE)
    JoAnne M Foody
    Section of Cardiovascular Medicine, Department of Medicine, Yale School of Medicine, New Haven, Connecticut, USA
    Am J Cardiol 95:483-5. 2005
    ....
  63. ncbi Influence of clinical trial enrollment on the quality of care and outcomes for patients with non-ST-segment elevation acute coronary syndromes
    David E Kandzari
    Duke Clinical Research Institute, Duke University Medical Center, Durham, NC 27705, USA
    Am Heart J 149:474-81. 2005
    ....
  64. ncbi Racial variations in treatment and outcomes of black and white patients with high-risk non-ST-elevation acute coronary syndromes: insights from CRUSADE (Can Rapid Risk Stratification of Unstable Angina Patients Suppress Adverse Outcomes With Early Impleme
    Ali F Sonel
    Center for Health Equity Research and Promotion, Pittsburgh, PA, USA
    Circulation 111:1225-32. 2005
    ..It is unknown whether racial disparities exist for other treatments for non-ST-segment elevation acute coronary syndromes (NSTE ACS) and how different treatments affect outcomes...
  65. ncbi Clinical characteristics, process of care, and outcomes of Hispanic patients presenting with non-ST-segment elevation acute coronary syndromes: results from Can Rapid risk stratification of Unstable angina patients Suppress ADverse outcomes with Early imp
    Mauricio G Cohen
    Division of Cardiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 7075, USA
    Am Heart J 152:110-7. 2006
    ..Data regarding the management of non-ST-segment elevation acute coronary syndromes (NSTE ACS) in Hispanic patients, the largest and fastest-growing minority in the United States, are scarce...
  66. ncbi Achieving standardization in clinical research: changing cacophony into harmony
    W Brian Gibler
    Ann Emerg Med 44:213-4. 2004
  67. ncbi Insurance coverage and care of patients with non-ST-segment elevation acute coronary syndromes
    James E Calvin
    Section of Cardiology, Rush University Medical Center, Chicago, Illinois 60612, USA
    Ann Intern Med 145:739-48. 2006
    ..The impact of insurance coverage on the care of patients with non-ST-segment elevation acute coronary syndromes (NSTE ACS) is unclear...
  68. ncbi Emergency department crowding: emergency physicians and cardiac risk stratification as part of the solution
    Andra L Blomkalns
    Ann Emerg Med 43:77-8. 2004
  69. ncbi Temporal trends in the use of early cardiac catheterization in patients with non-ST-segment elevation acute coronary syndromes (results from CRUSADE)
    Pierluigi Tricoci
    Division of Cardiology and the Duke Clinical Research Institute, Duke University Medical Center, Durham, North Carolina USA
    Am J Cardiol 98:1172-6. 2006
    ..In conclusion, despite the overall increase in the use of early catheterization, the gap between the use of an early invasive strategy in the highest and lowest risk patients remains large and tends to increase over time...
  70. ncbi Recent trends in the care of patients with non-ST-segment elevation acute coronary syndromes: insights from the CRUSADE initiative
    Rajendra H Mehta
    Duke Clinical Research Institute, Duke University Medical Center, Durham, NC 27715, USA
    Arch Intern Med 166:2027-34. 2006
    ..We sought to determine recent trends in adherence to guideline-based therapies for NSTE ACS...
  71. ncbi The impact of emergency department structure and care processes in delivering care for non-ST-segment elevation acute coronary syndromes
    Rajendra H Mehta
    Duke Clinical Research Institute, Duke University Medical Center, Durham, NC, USA
    Am Heart J 152:648-60. 2006
    ..We sought to assess the influence of emergency department (ED) structure and care processes on adherence to practice guidelines for the treatment of patients with non-ST-segment elevation acute coronary syndromes...
  72. ncbi Prevalence, predictors, and outcomes of patients with non-ST-segment elevation myocardial infarction and insignificant coronary artery disease: results from the Can Rapid risk stratification of Unstable angina patients Suppress ADverse outcomes with Early
    Manesh R Patel
    Division of Cardiology and Duke Clinical Research Institute, Duke University Medical Center, Durham, NC 27705, USA
    Am Heart J 152:641-7. 2006
    ..We sought to determine the prevalence, predictors, and outcomes of patients with NSTEMI and insignificant CAD...
  73. ncbi Sex differences in major bleeding with glycoprotein IIb/IIIa inhibitors: results from the CRUSADE (Can Rapid risk stratification of Unstable angina patients Suppress ADverse outcomes with Early implementation of the ACC/AHA guidelines) initiative
    Karen P Alexander
    Duke Clinical Research Institute, Duke University Medical Center, Durham, NC 27715, USA
    Circulation 114:1380-7. 2006
    ..The contribution of dosing to the observed sex-related differences in bleeding is unknown...
  74. ncbi Challenges in predicting the need for coronary artery bypass grafting at presentation in patients with non-ST-segment elevation acute coronary syndromes
    Rajendra H Mehta
    Duke Clinical Research Institute, Duke University Medical Center, Durham, North Carolina, USA
    Am J Cardiol 98:624-7. 2006
    ....
  75. ncbi Acute clopidogrel use and outcomes in patients with non-ST-segment elevation acute coronary syndromes undergoing coronary artery bypass surgery
    Rajendra H Mehta
    Division of Cardiology and the Duke Clinical Research Institute, Durham, North Carolina 27715, USA
    J Am Coll Cardiol 48:281-6. 2006
    ....
  76. ncbi Influence of timing of troponin elevation on clinical outcomes and use of evidence-based therapies for patients with non-ST-segment elevation acute coronary syndromes
    Matthew T Roe
    Duke Clinical Research Institute, Durham, NC 27705, USA
    Ann Emerg Med 45:355-62. 2005
    ....