Nathan C Gianneschi

Summary

Affiliation: University of California
Country: USA

Publications

  1. doi request reprint Enzyme-regulated topology of a cyclic peptide brush polymer for tuning assembly
    Zhao Wang
    Department of Chemistry and Biochemistry, University of California, San Diego, 9500 Gilman Dr, La Jolla, CA 92093, USA
    Chem Commun (Camb) 51:17108-11. 2015
  2. pmc Polymerization of a peptide-based enzyme substrate
    Michael E Hahn
    Department of Chemistry and Biochemistry, University of California San Diego, La Jolla, CA 92093, USA
    Chem Commun (Camb) 49:2873-5. 2013
  3. doi request reprint DNA-nanoparticle micelles as supramolecular fluorogenic substrates enabling catalytic signal amplification and detection by DNAzyme probes
    Miao Ping Chien
    Department of Chemistry and Biochemistry, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA
    Chem Commun (Camb) 47:167-9. 2011
  4. pmc Enzyme-directed assembly and manipulation of organic nanomaterials
    Michael E Hahn
    Department of Chemistry and Biochemistry, University of California, 9500 Gilman Drive, San Diego, La Jolla CA, USA
    Chem Commun (Camb) 47:11814-21. 2011
  5. doi request reprint Polycatechol Nanoparticle MRI Contrast Agents
    Yiwen Li
    Department of Chemistry and Biochemistry, University of California, San Diego, 9500 Gilman Dr, La Jolla, CA, 92093, USA
    Small 12:668-77. 2016
  6. pmc Controlling and switching the morphology of micellar nanoparticles with enzymes
    Ti Hsuan Ku
    Department of Chemistry and Biochemistry, University of California, San Diego, 9500 Gilman Drive, La Jolla, California 92093, USA
    J Am Chem Soc 133:8392-5. 2011
  7. pmc Smart lipids for programmable nanomaterials
    Matthew P Thompson
    Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, California 92093, USA
    Nano Lett 10:2690-3. 2010

Collaborators

  • Matthew P Thompson
  • Michael E Hahn
  • Miao Ping Chien
  • Yiwen Li
  • Zhao Wang
  • Ti Hsuan Ku
  • Yuran Huang
  • Fabio Carniato
  • Mauro Botta
  • Joseph P Patterson
  • Christopher M Andolina
  • Jill E Millstone
  • Miriam Scadeng
  • Jeffrey D Rinehart
  • Treffly B Ditri
  • Yijun Xie
  • Joshua S Figueroa
  • Swagat Sahu
  • Clare L M Leguyader
  • Lyndsay M Randolph
  • Lisa Adamiak
  • Norman H Olson
  • Timothy S Baker
  • Robert S Sinkovits
  • Anthony M Rush

Detail Information

Publications7

  1. doi request reprint Enzyme-regulated topology of a cyclic peptide brush polymer for tuning assembly
    Zhao Wang
    Department of Chemistry and Biochemistry, University of California, San Diego, 9500 Gilman Dr, La Jolla, CA 92093, USA
    Chem Commun (Camb) 51:17108-11. 2015
    ..The thermally-responsive nature of the materials could be attenuated by the addition of a proteolytic enzyme that causes the cyclic peptide side chains to be linearized. ..
  2. pmc Polymerization of a peptide-based enzyme substrate
    Michael E Hahn
    Department of Chemistry and Biochemistry, University of California San Diego, La Jolla, CA 92093, USA
    Chem Commun (Camb) 49:2873-5. 2013
    ..In contrast, when the peptides are densely arrayed on a nanoparticle derived from a self-assembled amphiphilic block-copolymer, they function with reduced activity as enzymatic substrates...
  3. doi request reprint DNA-nanoparticle micelles as supramolecular fluorogenic substrates enabling catalytic signal amplification and detection by DNAzyme probes
    Miao Ping Chien
    Department of Chemistry and Biochemistry, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA
    Chem Commun (Camb) 47:167-9. 2011
    ..However, they suffer from product inhibition limiting their widespread utility. Herein, this limitation is overcome utilizing a novel fluorogenic substrate design consisting of cooperatively assembled DNA-nanoparticle micelles...
  4. pmc Enzyme-directed assembly and manipulation of organic nanomaterials
    Michael E Hahn
    Department of Chemistry and Biochemistry, University of California, 9500 Gilman Drive, San Diego, La Jolla CA, USA
    Chem Commun (Camb) 47:11814-21. 2011
    ....
  5. doi request reprint Polycatechol Nanoparticle MRI Contrast Agents
    Yiwen Li
    Department of Chemistry and Biochemistry, University of California, San Diego, 9500 Gilman Dr, La Jolla, CA, 92093, USA
    Small 12:668-77. 2016
    ..The polycatechol nanoparticles are proposed as suitable for preclinical investigations into their viability as gadolinium-free, safe, and effective imaging agents for MRI contrast enhancement. ..
  6. pmc Controlling and switching the morphology of micellar nanoparticles with enzymes
    Ti Hsuan Ku
    Department of Chemistry and Biochemistry, University of California, San Diego, 9500 Gilman Drive, La Jolla, California 92093, USA
    J Am Chem Soc 133:8392-5. 2011
    ..Furthermore, the exceptional uniformity of these polymer-peptide particles makes them amenable to cryo-TEM reconstruction techniques lending insight into their internal structure...
  7. pmc Smart lipids for programmable nanomaterials
    Matthew P Thompson
    Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, California 92093, USA
    Nano Lett 10:2690-3. 2010
    ..The programmability, specificity, and reversibility of the switchable system are demonstrated via dynamic light scattering, transmission electron microscopy, and fluorescence microscopy...