Peter Gianaros

Summary

Affiliation: University of Pittsburgh
Country: USA

Publications

  1. pmc A review of neuroimaging studies of stressor-evoked blood pressure reactivity: emerging evidence for a brain-body pathway to coronary heart disease risk
    Peter J Gianaros
    Department of Psychiatry, University of Pittsburgh, 3811 O Hara Street, Pittsburgh, PA 15213, USA
    Neuroimage 47:922-36. 2009
  2. doi request reprint Brain systems for baroreflex suppression during stress in humans
    Peter J Gianaros
    Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    Hum Brain Mapp 33:1700-16. 2012
  3. pmc Potential neural embedding of parental social standing
    Peter J Gianaros
    Department of Psychiatry, University of Pittsburgh, 3811 O Hara Street, Pittsburgh, PA 15213, USA
    Soc Cogn Affect Neurosci 3:91-6. 2008
  4. pmc Preclinical atherosclerosis covaries with individual differences in reactivity and functional connectivity of the amygdala
    Peter J Gianaros
    Department of Psychiatry and Psychology, University of Pittsburgh, 3811 O Hara Street, Pittsburgh, Pennsylvania 15213, USA
    Biol Psychiatry 65:943-50. 2009
  5. pmc Heightened resting neural activity predicts exaggerated stressor-evoked blood pressure reactivity
    Peter J Gianaros
    Department of Psychiatry, University of Pittsburgh, 3811 O Hara St, Pittsburgh, PA 15213, USA
    Hypertension 53:819-25. 2009
  6. pmc Perigenual anterior cingulate morphology covaries with perceived social standing
    Peter J Gianaros
    Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Soc Cogn Affect Neurosci 2:161-73. 2007
  7. pmc Individual differences in stressor-evoked blood pressure reactivity vary with activation, volume, and functional connectivity of the amygdala
    Peter J Gianaros
    Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    J Neurosci 28:990-9. 2008
  8. pmc Prospective reports of chronic life stress predict decreased grey matter volume in the hippocampus
    Peter J Gianaros
    Department of Psychiatry, University of Pittsburgh, 3811 O Hara Street, Pittsburgh, PA 15213, USA
    Neuroimage 35:795-803. 2007
  9. ncbi request reprint Heightened functional neural activation to psychological stress covaries with exaggerated blood pressure reactivity
    Peter J Gianaros
    Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Hypertension 49:134-40. 2007
  10. pmc Higher blood pressure predicts lower regional grey matter volume: Consequences on short-term information processing
    Peter J Gianaros
    Department of Psychiatry, University of Pittsburgh, 3811 O Hara Street, Pittsburgh, PA 15213, USA
    Neuroimage 31:754-65. 2006

Research Grants

  1. Functional Organization of Cardiovascular Reactivity
    Peter Gianaros; Fiscal Year: 2007
  2. Neural Reactivity to Stress
    Peter Gianaros; Fiscal Year: 2009
  3. Neural Reactivity to Stress
    Peter J Gianaros; Fiscal Year: 2010
  4. Central Mechanisms for Cardioprotective Behavioral Effects of W-3 Fatty Acids
    Peter J Gianaros; Fiscal Year: 2010
  5. Neural Reactivity to Stress
    Peter Gianaros; Fiscal Year: 2009

Detail Information

Publications32

  1. pmc A review of neuroimaging studies of stressor-evoked blood pressure reactivity: emerging evidence for a brain-body pathway to coronary heart disease risk
    Peter J Gianaros
    Department of Psychiatry, University of Pittsburgh, 3811 O Hara Street, Pittsburgh, PA 15213, USA
    Neuroimage 47:922-36. 2009
    ..Contextually, the research reviewed here illustrates how behavioral medicine and health neuroscience methods can be integrated to help characterize the 'brain-body' pathways that mechanistically link stressful experiences with CHD risk...
  2. doi request reprint Brain systems for baroreflex suppression during stress in humans
    Peter J Gianaros
    Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    Hum Brain Mapp 33:1700-16. 2012
    ....
  3. pmc Potential neural embedding of parental social standing
    Peter J Gianaros
    Department of Psychiatry, University of Pittsburgh, 3811 O Hara Street, Pittsburgh, PA 15213, USA
    Soc Cogn Affect Neurosci 3:91-6. 2008
    ..Thus, these findings may provide insight into the neurodevelopmental pathways impacting socioeconomic disparities in health...
  4. pmc Preclinical atherosclerosis covaries with individual differences in reactivity and functional connectivity of the amygdala
    Peter J Gianaros
    Department of Psychiatry and Psychology, University of Pittsburgh, 3811 O Hara Street, Pittsburgh, Pennsylvania 15213, USA
    Biol Psychiatry 65:943-50. 2009
    ....
  5. pmc Heightened resting neural activity predicts exaggerated stressor-evoked blood pressure reactivity
    Peter J Gianaros
    Department of Psychiatry, University of Pittsburgh, 3811 O Hara St, Pittsburgh, PA 15213, USA
    Hypertension 53:819-25. 2009
    ..Heightened resting corticolimbic activity may represent a neurobiological correlate of an individual's predisposition for exaggerated stressor-evoked BP reactivity and possibly related cardiovascular risk...
  6. pmc Perigenual anterior cingulate morphology covaries with perceived social standing
    Peter J Gianaros
    Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Soc Cogn Affect Neurosci 2:161-73. 2007
    ..The pACC may represent a neuroanatomical substrate by which perceived social standing relates to mental and physical health...
  7. pmc Individual differences in stressor-evoked blood pressure reactivity vary with activation, volume, and functional connectivity of the amygdala
    Peter J Gianaros
    Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    J Neurosci 28:990-9. 2008
    ....
  8. pmc Prospective reports of chronic life stress predict decreased grey matter volume in the hippocampus
    Peter J Gianaros
    Department of Psychiatry, University of Pittsburgh, 3811 O Hara Street, Pittsburgh, PA 15213, USA
    Neuroimage 35:795-803. 2007
    ....
  9. ncbi request reprint Heightened functional neural activation to psychological stress covaries with exaggerated blood pressure reactivity
    Peter J Gianaros
    Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Hypertension 49:134-40. 2007
    ..Heightened stressor-induced activation of cingulate, prefrontal, insular, and cerebellar brain areas may represent a functional neural phenotype that characterizes individuals who are prone to show exaggerated cardiovascular reactivity...
  10. pmc Higher blood pressure predicts lower regional grey matter volume: Consequences on short-term information processing
    Peter J Gianaros
    Department of Psychiatry, University of Pittsburgh, 3811 O Hara Street, Pittsburgh, PA 15213, USA
    Neuroimage 31:754-65. 2006
    ..These findings suggest a functional relationship among men between higher blood pressure, lower regional grey matter volume, and poorer cognitive function that is independent of other risk factors and confounding medical conditions...
  11. pmc Parental education predicts corticostriatal functionality in adulthood
    Peter J Gianaros
    Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Cereb Cortex 21:896-910. 2011
    ..In speculation, adult alterations in corticostriatal functionality may represent facets of a neurobiological endophenotype linked to socioeconomic conditions of early development...
  12. pmc Neurobiological pathways linking socioeconomic position and health
    Peter J Gianaros
    Department of Psychiatry, Thomas Detre Hall, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Psychosom Med 72:450-61. 2010
    ....
  13. ncbi request reprint Is there a functional neural correlate of individual differences in cardiovascular reactivity?
    Peter J Gianaros
    Cardiovascular Behavioral Medicine Program, Department of Psychiatry, University of Pittsburgh School of Medicine, PA 15213, USA
    Psychosom Med 67:31-9. 2005
    ..The present study tested whether individuals who differ in the magnitude of their blood pressure reactions to a behavioral stressor also differ in their stressor-induced patterns of functional neural activation...
  14. pmc A greater reduction in high-frequency heart rate variability to a psychological stressor is associated with subclinical coronary and aortic calcification in postmenopausal women
    Peter J Gianaros
    Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    Psychosom Med 67:553-60. 2005
    ..We tested whether the reduction in HF-HRV to a psychological stressor relative to a baseline level is also associated with subclinical coronary or aortic atherosclerosis, as assessed by calcification in these vascular regions...
  15. pmc Anterior cingulate activity correlates with blood pressure during stress
    Peter J Gianaros
    Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    Psychophysiology 42:627-35. 2005
    ..These results support the hypothesis that the anterior cingulate cortex regulates blood pressure reactions to behavioral stressors in humans...
  16. pmc Cardiac vagal activity during psychological stress varies with social functioning in older women
    Victoria B Egizio
    Department of Psychology, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    Psychophysiology 45:1046-54. 2008
    ..These findings are at apparent odds with the polyvagal theory; however, they complement prior work suggesting that emotional self-regulation could plausibly modulate cardiac vagal control in association with social functioning...
  17. pmc Three-dimensional surface mapping of the caudate nucleus in late-life depression
    Meryl A Butters
    Department of Psychiatry, University of Pittsburgh, and Western Psychiatric Institute and Clinic, 3811 O Hara St, Pittsburgh, PA 15213, USA
    Am J Geriatr Psychiatry 17:4-12. 2009
    ....
  18. pmc Gain in adiposity across 15 years is associated with reduced gray matter volume in healthy women
    Isabella Soreca
    Department of Psychiatry, University of Pittsburgh, 3811 O Hara Street, Pittsburgh, PA 15213, USA
    Psychosom Med 71:485-90. 2009
    ..Cross-sectional results indicate that reduced GMV may be associated with excess body weight...
  19. pmc Subjective socioeconomic status and presence of the metabolic syndrome in midlife community volunteers
    Stephen B Manuck
    Department of Psychology, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Psychosom Med 72:35-45. 2010
    ....
  20. pmc Resting state functional connectivity within the cingulate cortex jointly predicts agreeableness and stressor-evoked cardiovascular reactivity
    John P Ryan
    Department of Psychiatry, University of Pittsburgh, USA
    Neuroimage 55:363-70. 2011
    ..Functional connectivity within the cingulate appears to link Agreeableness and a risk factor for cardiovascular disease, stressor-evoked BP reactivity...
  21. pmc Cardiac vagal control in nonmedicated depressed women and nondepressed controls: impact of depression status, lifetime trauma history, and respiratory factors
    Jill M Cyranowski
    Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, 3811 O Hara Street, Pittsburgh, PA 15213, USA
    Psychosom Med 73:336-43. 2011
    ..Impairment in cardiac parasympathetic (vagal) control may confer risk for cardiac mortality in depressed populations...
  22. ncbi request reprint Long-chain omega-3 fatty acid intake is associated positively with corticolimbic gray matter volume in healthy adults
    Sarah M Conklin
    Department of Psychiatry, University of Pittsburgh, School of Medicine, Pittsburgh, PA 15260, United States
    Neurosci Lett 421:209-12. 2007
    ..Here, we test whether omega-3 fatty acid intake in humans varies with individual differences in gray matter volume, an in vivo, systems-level index of neuronal integrity...
  23. ncbi request reprint Is cardiovascular reactivity associated with atherosclerosis among hypertensives?
    Peter J Gianaros
    Cardiovascular Behavioral Medicine Research Program, University of Pittsburgh, Pennsylvania, USA
    Hypertension 40:742-7. 2002
    ..Among hypertensives, exaggerated behaviorally evoked cardiovascular reactivity appears to be uniquely associated with greater carotid intima-media thickness but not with carotid plaque occurrence...
  24. pmc Greater intima-media thickness in the carotid bulb is associated with reduced baroreflex sensitivity
    Peter J Gianaros
    Cardiovascular Behavioral Medicine Research Program, University of Pittsburgh, Pennsylvania, USA
    Am J Hypertens 15:486-91. 2002
    ..These results suggest that subclinical atherosclerosis, specifically in a region with high baroreceptor density, is associated with a reduced sensitivity of the baroreflex...
  25. doi request reprint Trait negative affect: toward an integrated model of understanding psychological risk for impairment in cardiac autonomic function
    Maria E Bleil
    Department of Psychiatry, University of California San Francisco, 3333 California Street, Suite 465, San Francisco, CA 94143 0848, USA
    Psychosom Med 70:328-37. 2008
    ..g., autonomic nervous system [ANS] dysfunction), the degree to which a general tendency to experience negative emotions may account for these relations is not known...
  26. ncbi request reprint Vagal function in health and disease: studies in Pittsburgh
    J Richard Jennings
    Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, 15213, Pittsburgh, PA, USA
    Physiol Behav 77:693-8. 2002
    ..Overall, the specificity and sensitivity of vagal responses to higher level cortical function is supported by our research...
  27. pmc Relationship between temporal changes in cardiac parasympathetic activity and motion sickness severity
    Peter J Gianaros
    Cardiovascular Behavioral Medicine Research Program, Western Psychiatric Institute and Clinic, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    Psychophysiology 40:39-44. 2003
    ..These results suggest that a time-related decrease in cardiac parasympathetic activity may be an important correlate of nausea and motion sickness across different evocative contexts...
  28. ncbi request reprint Regional cerebral blood flow correlates with heart period and high-frequency heart period variability during working-memory tasks: Implications for the cortical and subcortical regulation of cardiac autonomic activity
    Peter J Gianaros
    Cardiovascular Behavioral Medicine Research Program, The University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Psychophysiology 41:521-30. 2004
    ..These findings replicate and extend a small number of functional neuroimaging studies that suggest an important role for both cortical and subcortical brain systems in human cardiac autonomic regulation...
  29. pmc Altered functioning of the executive control circuit in late-life depression: episodic and persistent phenomena
    Howard J Aizenstein
    Department of Psychiatry, University of Pittsburgh, and Western Psychiatric Institute and Clinic, 3811 O Hara Street, Pittsburgh, PA 15213, USA
    Am J Geriatr Psychiatry 17:30-42. 2009
    ..To characterize the functional neuroanatomy of late-life depression (LLD) by probing for both episodic and persistent alterations in the executive-control circuit of elderly adults...
  30. pmc Interleukin-6 covaries inversely with hippocampal grey matter volume in middle-aged adults
    Anna L Marsland
    Behavioral Immunology Laboratory, University of Pittsburgh, PA 15260, USA
    Biol Psychiatry 64:484-90. 2008
    ..In the current study, we extend this work to test whether systemic inflammation is associated with reduced grey matter volume of the hippocampus...
  31. ncbi request reprint Stimulated production of proinflammatory cytokines covaries inversely with heart rate variability
    Anna L Marsland
    Behavioral Immunology Laboratory, Department of Psychology, University of Pittsburgh, Pittsburgh, PA 15260, USA
    Psychosom Med 69:709-16. 2007
    ..As yet, no direct human evidence links parasympathetic activity to inflammatory competence...
  32. pmc Susceptibility to nausea and motion sickness as a function of the menstrual cycle
    Robert L Matchock
    Department of Psychology, The Pennsylvania State University, Altoona Campus, Altoona, Pennsylvania 16601, USA
    Womens Health Issues 18:328-35. 2008
    ..The present study examined whether susceptibility to nausea and other symptoms of vection-induced motion sickness vary as a function of phase of the menstrual cycle, as research findings in this area are sparse and contradictory...

Research Grants9

  1. Functional Organization of Cardiovascular Reactivity
    Peter Gianaros; Fiscal Year: 2007
    ....
  2. Neural Reactivity to Stress
    Peter Gianaros; Fiscal Year: 2009
    ....
  3. Neural Reactivity to Stress
    Peter J Gianaros; Fiscal Year: 2010
    ....
  4. Central Mechanisms for Cardioprotective Behavioral Effects of W-3 Fatty Acids
    Peter J Gianaros; Fiscal Year: 2010
    ....
  5. Neural Reactivity to Stress
    Peter Gianaros; Fiscal Year: 2009
    ....