R Mark Ghobrial

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi request reprint Donor and recipient outcomes in right lobe adult living donor liver transplantation
    Rafik M Ghobrial
    Department of Surgery, The David Geffen School of Medicine at UCLA, Los Angeles, CA, USA
    Liver Transpl 8:901-9. 2002
  2. pmc Analysis of long-term outcomes of 3200 liver transplantations over two decades: a single-center experience
    Ronald W Busuttil
    Dumont UCLA Liver Transplant Center, Department of Surgery, David Geffen School of Medicine at UCLA, Los Angeles, California 90095, USA
    Ann Surg 241:905-16; discussion 916-8. 2005
  3. ncbi request reprint Retransplantation for recurrent hepatitis C
    Rafik M Ghobrial
    Department of Surgery, Division of Liver and Pancreas Transplantation, David Geffen School of Medicine at University of California Los Angeles, Los Angeles, CA 90095, USA
    Liver Transpl 8:S38-43. 2002
  4. doi request reprint Recurrence of hepatocellular carcinoma following liver transplantation: a review of preoperative and postoperative prognostic indicators
    Michael A Zimmerman
    Dumont University of California, Los Angeles, Transplant Center, 77 120 CHS, Box 957054, 10833 Le Conte Ave, Los Angeles, CA 90095 7054, USA
    Arch Surg 143:182-8; discussion 188. 2008
  5. doi request reprint Longterm outcomes for whole and segmental liver grafts in adult and pediatric liver transplant recipients: a 10-year comparative analysis of 2,988 cases
    Johnny C Hong
    Department of Surgery, Dumont UCLA Transplant Center, Pfleger Liver Institute, David Geffen School of Medicine at the University of California, Los Angeles, Los Angeles, CA 90095 7054, USA
    J Am Coll Surg 208:682-9; discusion 689-91. 2009
  6. ncbi request reprint Anemia in liver transplant recipients undergoing antiviral treatment for recurrent hepatitis C
    Sammy Saab
    Department of Medicine, University of California at Los Angeles, Los Angeles, CA 90095, USA
    Liver Transpl 13:1032-8. 2007
  7. ncbi request reprint Mortality predictors in liver transplant recipients with recurrent hepatitis C cirrhosis
    Sammy Saab
    Division of Digestive Diseases, Department of Medicine, UCLA Medical Center, University of California Los Angeles, 200 Medical Plaza, Los Angeles, CA 90095, USA
    Liver Int 25:940-5. 2005
  8. doi request reprint Pretransplant variables associated with quality of life in liver transplant recipients
    Sammy Saab
    Department of Medicine, University of California, Los Angeles, CA 90095, USA
    Liver Int 28:1087-94. 2008
  9. ncbi request reprint MELD score predicts 1-year patient survival post-orthotopic liver transplantation
    Sammy Saab
    Division of Digestive Diseases, University of California Los Angeles, Los Angeles, CA, USA
    Liver Transpl 9:473-6. 2003
  10. ncbi request reprint Outcomes of hepatitis C- and hepatitis B core antibody-positive grafts in orthotopic liver transplantation
    Sammy Saab
    Department of Medicine, Division of Digestive Diseases, Dumont UCLA Liver Transplant Center, University of California Los Angeles, 90095, USA
    Liver Transpl 9:1053-61. 2003

Research Grants

Collaborators

Detail Information

Publications60

  1. ncbi request reprint Donor and recipient outcomes in right lobe adult living donor liver transplantation
    Rafik M Ghobrial
    Department of Surgery, The David Geffen School of Medicine at UCLA, Los Angeles, CA, USA
    Liver Transpl 8:901-9. 2002
    ..Continuous standardized reporting of ALDLT outcomes is required to allow successful and safe implementation of the procedure...
  2. pmc Analysis of long-term outcomes of 3200 liver transplantations over two decades: a single-center experience
    Ronald W Busuttil
    Dumont UCLA Liver Transplant Center, Department of Surgery, David Geffen School of Medicine at UCLA, Los Angeles, California 90095, USA
    Ann Surg 241:905-16; discussion 916-8. 2005
    ..This work analyzes the experience of nearly 2 decades by the same team in a single center. Outcomes of OLT and factors affecting survival were analyzed...
  3. ncbi request reprint Retransplantation for recurrent hepatitis C
    Rafik M Ghobrial
    Department of Surgery, Division of Liver and Pancreas Transplantation, David Geffen School of Medicine at University of California Los Angeles, Los Angeles, CA 90095, USA
    Liver Transpl 8:S38-43. 2002
    ..5. Good outcomes are obtained in selected patients when re-OLT is performed early in the course of recurrent disease before transplant recipients become critically ill...
  4. doi request reprint Recurrence of hepatocellular carcinoma following liver transplantation: a review of preoperative and postoperative prognostic indicators
    Michael A Zimmerman
    Dumont University of California, Los Angeles, Transplant Center, 77 120 CHS, Box 957054, 10833 Le Conte Ave, Los Angeles, CA 90095 7054, USA
    Arch Surg 143:182-8; discussion 188. 2008
    ..To review the preoperative and postoperative variables that predict hepatocellular carcinoma (HCC) recurrence following orthotopic liver transplantation (OLT)...
  5. doi request reprint Longterm outcomes for whole and segmental liver grafts in adult and pediatric liver transplant recipients: a 10-year comparative analysis of 2,988 cases
    Johnny C Hong
    Department of Surgery, Dumont UCLA Transplant Center, Pfleger Liver Institute, David Geffen School of Medicine at the University of California, Los Angeles, Los Angeles, CA 90095 7054, USA
    J Am Coll Surg 208:682-9; discusion 689-91. 2009
    ..We compared 10-year outcomes for liver transplant patients who received whole grafts (WLT), split grafts from deceased donors (SLT), and partial grafts from living donors (LDLT)...
  6. ncbi request reprint Anemia in liver transplant recipients undergoing antiviral treatment for recurrent hepatitis C
    Sammy Saab
    Department of Medicine, University of California at Los Angeles, Los Angeles, CA 90095, USA
    Liver Transpl 13:1032-8. 2007
    ..01) and age (P = 0.02) were found to be independent predictors of anemia. Anemia is common in liver transplant recipients treated for recurrent HCV. Special vigilance is required for older patients and patients with a low BMI...
  7. ncbi request reprint Mortality predictors in liver transplant recipients with recurrent hepatitis C cirrhosis
    Sammy Saab
    Division of Digestive Diseases, Department of Medicine, UCLA Medical Center, University of California Los Angeles, 200 Medical Plaza, Los Angeles, CA 90095, USA
    Liver Int 25:940-5. 2005
    ..The aim of this study was to identify predictors of survival in liver transplant recipients who develop cirrhosis from recurrent HCV...
  8. doi request reprint Pretransplant variables associated with quality of life in liver transplant recipients
    Sammy Saab
    Department of Medicine, University of California, Los Angeles, CA 90095, USA
    Liver Int 28:1087-94. 2008
    ..Our goal is to identify pretransplant variables associated with post-transplant quality of life in liver transplant recipients...
  9. ncbi request reprint MELD score predicts 1-year patient survival post-orthotopic liver transplantation
    Sammy Saab
    Division of Digestive Diseases, University of California Los Angeles, Los Angeles, CA, USA
    Liver Transpl 9:473-6. 2003
    ..99; 95% CI 1.07, 3.7). The MELD stratum is better associated with 1-year patient survival in liver transplant recipients than UNOS statuses. Patient survival was worse with higher MELD scores...
  10. ncbi request reprint Outcomes of hepatitis C- and hepatitis B core antibody-positive grafts in orthotopic liver transplantation
    Sammy Saab
    Department of Medicine, Division of Digestive Diseases, Dumont UCLA Liver Transplant Center, University of California Los Angeles, 90095, USA
    Liver Transpl 9:1053-61. 2003
    ..Furthermore, the use of combined HBcAb+/HCV+ grafts did not impact patient or graft survival. This provides a potential new pool of donor livers that can be used for transplantation in select patients...
  11. ncbi request reprint Outcome of liver transplantation in septuagenarians: a single-center experience
    Gerald S Lipshutz
    Center for Surgical Outcomes and Quality, Department of Surgery, David Geffen School of Medicine at UCLA, Room 77 120 CHS, Los Angeles, CA 90095, USA
    Arch Surg 142:775-81; discussion 781-4. 2007
    ..This work compares post-liver transplant survival in septuagenarians with that of patients aged 50 to 59 years...
  12. ncbi request reprint Outcomes of acute rejection after interferon therapy in liver transplant recipients
    Sammy Saab
    Department of Medicine, Dumont UCLA Liver Transplant Center, Los Angeles, CA, USA
    Liver Transpl 10:859-67. 2004
    ..Interferon-based therapy may lead to acute rejection and subsequent graft loss and should therefore be used with caution. Treated recipients may also develop progressive cirrhosis despite achieving a sustained virological response...
  13. ncbi request reprint Preoperative imaging in adult-to-adult living related liver transplant donors: what surgeons want to know
    Piyaporn Limanond
    Department of Radiology, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, CA 90095 1721, USA
    J Comput Assist Tomogr 28:149-57. 2004
    ..The roles of high-field magnetic resonance (MR) imaging, MR angiography, MR cholangiopancreatography, multidetector-row computed tomography (CT) angiography, and CT cholangiography in the workup are discussed...
  14. ncbi request reprint Efficacy of CT angiography for preoperative vascular mapping in adult to adult living related liver transplant donors
    Piyaporn Apisarnthanarak
    Department of Radiology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA
    J Med Assoc Thai 94:98-105. 2011
    ..To assess the utility of CT angiography (CTA) in preoperative mapping of hepatic vascular anatomy in adult-to-adult living related liver transplant (LRLT) donors...
  15. ncbi request reprint Portocaval hemitransposition in pediatric liver transplant recipients: a single-center experience
    Gerald S Lipshutz
    Dumont UCLA Liver Transplant Center, Department of Surgery, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA
    Liver Transpl 12:1097-103. 2006
    ..Appropriate selection of recipient and type of donor graft are essential for good outcomes. Portocaval hemitransposition should be used cautiously and as a last resort to establish portovenous inflow...
  16. pmc Optimal utilization of donor grafts with extended criteria: a single-center experience in over 1000 liver transplants
    Andrew M Cameron
    Dumont UCLA Liver Transplant Center, and Department of Surgery, David Geffen School of Medicine at UCLA, 10833 LeConte Avenue, Los Angeles, CA 90095, USA
    Ann Surg 243:748-53; discussion 753-5. 2006
    ..This work aimed to identify factors that impact survival outcomes for extended criteria donors (ECD) and developed an ECD scoring system to facilitate graft-recipient matching and optimize utilization of ECDs...
  17. ncbi request reprint Employment and quality of life in liver transplant recipients
    Sammy Saab
    Department of Medicine, University of California, Los Angeles, Los Angeles, CA, USA
    Liver Transpl 13:1330-8. 2007
    ....
  18. doi request reprint Analysis of liver transplant outcomes for United Network for Organ Sharing recipients 60 years old or older identifies multiple model for end-stage liver disease-independent prognostic factors
    Thomas A Aloia
    Division of Transplantation, Department of Surgery, Weill Cornell Medical College, Methodist Hospital, Houston, TX 77030, USA
    Liver Transpl 16:950-9. 2010
    ..By optimization of donor selection for recipients over the age of 60 years, clinical utilization of the ORPS model may enhance organ utilization for all patients awaiting OLT...
  19. ncbi request reprint Changing faces of liver transplantation: partial-liver grafts for adults
    John F Renz
    Dumont UCLA Transplantation Center, Room 77 120 CHS, 10833 Le Conte Ave, Los Angeles, CA 90095, USA
    J Hepatobiliary Pancreat Surg 10:31-44. 2003
    ..This manuscript details current technical considerations for the performance of adult-to-adult living-donor and split-liver transplantation, summarizes current outcomes, and explores the ethical dilemma of living-donation...
  20. ncbi request reprint MELD fails to measure quality of life in liver transplant candidates
    Sammy Saab
    Department of Medicine, David Geffen School of Medicine, University of California Los Angeles, CA 90095, USA
    Liver Transpl 11:218-23. 2005
    ..The presence of ascites and/or encephalopathy was significantly associated with poor quality of life. CTP correlates better to QOL, probably because it contains ascites and encephalopathy...
  21. doi request reprint Does race influence outcomes after primary liver transplantation? A 23-year experience with 2,700 patients
    Johnny C Hong
    Dumont UCLA Transplant Center, Pfleger Liver Institute, Department of Surgery, David Geffen School of Medicine at University of California, Los Angeles, CA 90095 7054, USA
    J Am Coll Surg 206:1009-16; discussion 1016-8. 2008
    ..This study was undertaken to evaluate longterm outcomes for LT in African-American (AA) recipients compared with recipients of other races and to determine factors responsible for any observed differences...
  22. ncbi request reprint A model to predict the development of mental status changes of unclear cause after liver transplantation
    Fasiha Kanwal
    Division of Digestive Diseases, David Geffen School of Medicine at University of California at Los Angeles, CA, USA
    Liver Transpl 9:1312-9. 2003
    ..A simple model can be used to calculate the risk for developing altered mental status post-LT...
  23. ncbi request reprint Acquired hemophilia A after liver transplantation: a case report
    Garrett M Hisatake
    The Dumont UCLA Transplant Center, Los Angeles, CA 90095 7054, USA
    Liver Transpl 9:523-6. 2003
    ..High levels of factor VIII inhibitor represents an absolute contraindication to liver donation...
  24. ncbi request reprint The utility of MRCP in preoperative mapping of biliary anatomy in adult-to-adult living related liver transplant donors
    Piyaporn Limanond
    Department of Radiology, David Geffen School of Medicine at UCLA, Los Angeles, California 90005 1721, USA
    J Magn Reson Imaging 19:209-15. 2004
    ..To assess the utility of magnetic resonance cholangiopancreatography (MRCP) in preoperative mapping of biliary anatomy in adult-to-adult living related liver transplant (LRLT) donors...
  25. ncbi request reprint Gastric radiation enteritis after intra-arterial yttrium-90 microsphere therapy for early stage hepatocellular carcinoma
    Thomas A Aloia
    Department of Surgery, Division of Transplantation, The Methodist Hospital, Houston, Texas 77030, USA
    Exp Clin Transplant 7:141-4. 2009
    ..To demonstrate the potential risks associated with this treatment, in the following case report, we describe a patient with early stage hepatocellular carcinoma who experienced severe toxicity from intra-arterial radiotherapy...
  26. ncbi request reprint Macrovesicular hepatic steatosis in living related liver donors: correlation between CT and histologic findings
    Piyaporn Limanond
    Department of Radiology, David Geffen School of Medicine at UCLA, 10833 Le Conte Ave, Los Angeles, CA 90095 1721, USA
    Radiology 230:276-80. 2004
    ..To assess degree of macrovesicular steatosis with unenhanced computed tomography (CT) and correlate it with histologic findings in potential donors for living related liver transplantation...
  27. pmc Liver transplantation for fulminant hepatic failure: experience with more than 200 patients over a 17-year period
    Douglas G Farmer
    Department of Surgery, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA 90095, USA
    Ann Surg 237:666-75; discussion 675-6. 2003
    ..To analyze outcomes after liver transplantation (LT) in patients with fulminant hepatic failure (FHF) with emphasis on pretransplant variables that can potentially help predict posttransplant outcome...
  28. pmc New era of liver transplantation for hepatitis B: a 17-year single-center experience
    Dean M Anselmo
    Department of Surgery, Dumont UCLA Liver Transplant Center, UCLA School of Medicine, Los Angeles, California 90095 7054, USA
    Ann Surg 235:611-9; discussion 619-20. 2002
    ..To evaluate the variables affecting orthotopic liver transplantation (OLT) outcome for hepatitis B virus (HBV) in a large patient cohort over a 17-year period...
  29. ncbi request reprint Liver transplantation for HELLP syndrome
    Ali Zarrinpar
    Dumont UCLA Transplant Center, Department of Surgery, David Geffen School of Medicine at UCLA, Los Angeles, California, USA
    Am Surg 73:1013-6. 2007
    ..This is the largest single-center report of LT for HELLP. Early recognition and transfer to a transplant center will yield best results with this challenging complication of pregnancy...
  30. ncbi request reprint Operative parameters that predict the outcomes of hepatic transplantation
    James F Markmann
    Department of Surgery, School of Medicine, Hospital of the University of Pennsylvania, 4th Floor Silverstein, 3400 Spruce Street, Philadelphia, PA 19104, USA
    J Am Coll Surg 196:566-72. 2003
    ..A comprehensive analysis of operative parameters on the outcomes of liver transplantation has not been reported...
  31. pmc Outcomes of 385 adult-to-adult living donor liver transplant recipients: a report from the A2ALL Consortium
    Kim M Olthoff
    Department of Surgery, University of Pennsylvania, Philadelphia, PA 19104, USA
    Ann Surg 242:314-23, discussion 323-5. 2005
    ....
  32. pmc Liver transplantation criteria for hepatocellular carcinoma should be expanded: a 22-year experience with 467 patients at UCLA
    John P Duffy
    Dumont UCLA Transplant Center, Department of Surgery, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA
    Ann Surg 246:502-9; discussion 509-11. 2007
    ..To assess the efficacy of orthotopic liver transplantation (OLT) for hepatocellular carcinoma (HCC) and the impact of current staging criteria on long term survival...
  33. ncbi request reprint Preoperative characteristics and intraoperative transfusion and vasopressor requirements in patients with low vs. high MELD scores
    Victor W Xia
    Department of Anesthesiology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095 1778, USA
    Liver Transpl 12:614-20. 2006
    ..In conclusion, these data suggest that pretransplant MELD scores provide important information for perioperative management of patients undergoing liver transplantation...
  34. ncbi request reprint When shouldn't we retransplant?
    Michael A Zimmerman
    Department of Surgery, Division of Liver and Pancreas Transplantation, The Pfleger Liver Institute, The Dumont UCLA Transplant Center, David Geffen School of Medicine at the University of California Los Angeles, Los Angeles, CA 90095 7054, USA
    Liver Transpl . 2005
    ..5. Accurate definitions of acceptable outcomes after retransplantation and "futile re-OLT" are desperately needed...
  35. ncbi request reprint Is it cost-effective to treat recurrent hepatitis C infection in orthotopic liver transplantation patients?
    Sammy Saab
    Department of Medicine, University of California Los Angeles, USA
    Liver Transpl 8:449-57. 2002
    ..Our model was sensitive to antiviral drug costs, cirrhosis rate, and sustained viral response. Patients with a progressive course of recurrent HCV are likely to have the greatest gain from antiviral therapy...
  36. ncbi request reprint The MELD score in advanced liver disease: association with clinical portal hypertension and mortality
    Sammy Saab
    Department of Medicine, University of California at Los Angeles 90095, and Department of Medicine at Olive View Medical Center, Pasadena, USA
    Exp Clin Transplant 4:395-9. 2006
    ..However, clinical factors that affect the MELD score are unknown. We sought to identify predictors of mortality for potential transplant patients and examine factors that might predict changes in MELD score...
  37. ncbi request reprint Conversion from intravenous to intramuscular hepatitis B immune globulin in combination with lamivudine is safe and cost-effective in patients receiving long-term prophylaxis to prevent hepatitis B recurrence after liver transplantation
    Steven Huy Han
    Division of Digestive Diseases, UCLA School of Medicine, Los Angeles, CA, USA
    Liver Transpl 9:182-7. 2003
    ....
  38. pmc Donor morbidity after living donation for liver transplantation
    Rafik M Ghobrial
    Department of Surgery, University of California Los Angeles, Los Angeles, California, USA
    Gastroenterology 135:468-76. 2008
    ..The rate and severity of complications in living donors were investigated in the 9-center Adult-to-Adult Living Donor Liver Transplantation Cohort Study (A2ALL)...
  39. ncbi request reprint Discordance between ALT values and fibrosis in liver transplant recipients treated with ribavirin for recurrent hepatitis C
    Sammy Saab
    Department of Medicine, Dumont UCLA Liver Transplant Center, University of California Los Angeles, USA
    Am J Transplant 3:328-33. 2003
    ..Our results suggest that HCV disease can progress despite a significant decrease in ALT values. ALT values are inadequate markers of the ribavirin monotherapy and can lead to erroneous conclusions of efficacy...
  40. ncbi request reprint Hepatocellular carcinoma screening in patients waiting for liver transplantation: a decision analytic model
    Sammy Saab
    Department of Medicine, Dumont UCLA Liver Transplant Center, University of California Los Angeles, USA
    Liver Transpl 9:672-81. 2003
    ..U/S screening strategy is the preferred screening strategy based on the lowest ICER. Ultimately, costs of the screening modalities determine the most cost-effective strategy...
  41. ncbi request reprint Hepatitis C positive grafts may be used in orthotopic liver transplantation: a matched analysis
    Sammy Saab
    Division of Digestive Diseases, Dumont UCLA Liver Transplant Center, University of California, Los Angeles, CA 90095, USA
    Am J Transplant 3:1167-72. 2003
    ..Our results suggest that HCV-positive grafts can be used in a HCV liver transplant recipient...
  42. ncbi request reprint Predictors of hyperkalemia in the prereperfusion, early postreperfusion, and late postreperfusion periods during adult liver transplantation
    Victor W Xia
    Department of Anesthesiology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095 1778, USA
    Anesth Analg 105:780-5. 2007
    ..Hyperkalemia poses serious hazards to patients undergoing orthotopic liver transplantation (OLT), and its predictors have not been thoroughly examined...
  43. ncbi request reprint Predictors of survival after liver transplantation for hepatocellular carcinoma associated with Hepatitis C
    Mitsugi Shimoda
    Dumont UCLA Liver Transplant Center, Department of Surgery, UCLA School of Medicine, 90095, USA
    Liver Transpl 10:1478-86. 2004
    ..Early pTNM stage, adjuvant chemotherapy, and preoperative chemoembolization were associated with positive outcomes for patients who underwent OLT for concomitant HCV and HCC...
  44. ncbi request reprint Budd-Chiari syndrome
    Michael A Zimmerman
    Division of Liver and Pancreas Transplantation, Department of Surgery, The Pfleger Liver Institute, The Dumont UCLA Transplant Center, The David Geffen School of Medicine at the University of California Los Angeles, Los Angeles, CA 90095, USA
    Clin Liver Dis 10:259-73, viii. 2006
    ....
  45. ncbi request reprint Technical and logistical considerations of in situ split-liver transplantation for two adults: Part II. Creation of left segment I-IV and right segment V-VIII grafts
    Hasan Yersiz
    Dumont UCLA Transplant Center, Department of Surgery, University of California, Los Angeles, CA, USA
    Liver Transpl 8:78-81. 2002
  46. ncbi request reprint Future of adult living donor liver transplantation
    R Mark Ghobrial
    Department of Surgery, Division of Liver and Pancreas Transplantation, The Dumont UCLA Transplant Center, David Geffen School of Medicine at University of California Los Angeles, Los Angeles, CA 90095 7054, USA
    Liver Transpl 9:S73-9. 2003
  47. ncbi request reprint Predictors of outcomes after pediatric liver transplantation: an analysis of more than 800 cases performed at a single institution
    Douglas G Farmer
    Department of Surgery, David Geffen School of Medicine at UCLA, University of California, Los Angeles, CA 90095 7054, USA
    J Am Coll Surg 204:904-14; discussion 914-6. 2007
    ..Unfortunately, there are few studies with substantial numbers of patients that identify outcomes predictors. The goal of this study was to determine factors that influence outcomes in a large, single-center cohort of PLTx...
  48. pmc Pretransplant model to predict posttransplant survival in liver transplant patients
    Rafik M Ghobrial
    Dumont UCLA Transplant Center, Department of Surgery, The David Geffen School of Medicine at UCLA, Los Angeles, California 90095, USA
    Ann Surg 236:315-22; discussion 322-3. 2002
    ..To develop a prognostic model that determines patient survival outcomes after orthotopic liver transplantation (OLT) using readily available pretransplant variables...
  49. pmc Genes involved in viral carcinogenesis and tumor initiation in hepatitis C virus-induced hepatocellular carcinoma
    Valeria R Mas
    Division of Transplantation, Department of Surgery, Virginia Commonwealth University, Richmond, Virginia, USA
    Mol Med 15:85-94. 2009
    ..Characteristic gene signatures were identified at different stages of HCV-HCC progression. A set of genes were identified to predict whether the cirrhotic tissue was associated with HCC...
  50. ncbi request reprint Long-term analysis of combined liver and kidney transplantation at a single center
    Richard Ruiz
    Department of Surgery, Dumont UCLA Transplant Center, University of California, Los Angeles, USA
    Arch Surg 141:735-41; discussion 741-2. 2006
    ..To analyze use of combined liver and kidney transplantation (CLKT) for patients with chronic primary diseases of both organs and for patients with hepatorenal syndrome...
  51. doi request reprint Vascular complications of orthotopic liver transplantation: experience in more than 4,200 patients
    John P Duffy
    Department of Surgery, Dumont UCLA Transplant Center, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA
    J Am Coll Surg 208:896-903; discussion 903-5. 2009
    ..This study was undertaken to evaluate the incidence of major vascular complications after OLT, determine efficacy of therapies, and identify factors influencing longterm outcomes...
  52. pmc Effect of nonviral factors on hepatitis C recurrence after liver transplantation
    Andrew M Cameron
    Department of Surgery, Dumont UCLA Liver Transplant Center, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA
    Ann Surg 244:563-71. 2006
    ..This study examined donor, recipient, and operative variables to identify factors that affect recurrence of HCV post-OLT to facilitate graft-recipient matching...
  53. pmc Class I MHC allochimeric presentation of composite immunogenic and self epitopes induces tolerance to genetically diverse rat strains
    Natalya V Semiletova
    The Dumont UCLA Transplant Center, Division of Liver and Pancreas Transplantation, Department of Surgery, David Geffen School of Medicine at UCLA, 10833 Le Conte Avenue, 77 120 CHS, Los Angeles, CA 90095 7054, USA
    Cell Immunol 248:48-58. 2007
    ....
  54. pmc Timing of referral impacts surgical outcomes in patients undergoing repair of bile duct injuries
    Craig P Fischer
    Department of Surgery, Weill Cornell Medical College, The Methodist Hospital Department of Surgery Houston, TX, USA
    HPB (Oxford) 11:32-7. 2009
    ..Additionally, we examined the impact of delayed referral to our centre on short- and long-term outcomes after surgical repair of BDI...
  55. ncbi request reprint Posttransplant administration of allochimeric major histocompatibility complex class-I-molecules induces true transplantation tolerance
    Natalya Semiltova
    The Dumont UCLA Transplant Center, Division of Liver and Pancreas Transplantation, Department of Surgery, David Geffen School of Medicine at UCLA, Los Angeles, California 90095 7054, USA
    Transplantation 75:550-3. 2003
    ..Here, we investigated the ability of posttransplant allochimeric administration to induce tolerance and concomitantly inhibit chronic rejection...
  56. ncbi request reprint Retrospective analysis of the results of liver transplantation for adults with severe hepatopulmonary syndrome
    Eric A Collisson
    David Geffen School of Medicine, University of California at Los Angeles School of Medicine, Los Angeles, CA 90095, USA
    Liver Transpl 8:925-31. 2002
    ..This supports the newly implemented United Network for Organ Sharing (UNOS) criteria, that LT for HPS may be extended to include patients with Pa(O2) < 60 mm Hg...
  57. ncbi request reprint Giant cavernous liver hemangiomas: effect of operative approach on outcome
    Susan M Lerner
    Department of Surgery, Pennsylvania State Milton S Hershey Medical Center, Hershey, USA
    Arch Surg 139:818-21; discussion 821-3. 2004
    ..The choice of operative technique for resection of giant cavernous hepatic hemangiomas has an effect on outcome...
  58. ncbi request reprint Incisional hernia after liver transplantation
    Andrew J Vardanian
    Division of Liver and Pancreas Transplantation, Department of Surgery, Dumont UCLA Transplant Center, David Geffen School of Medicine at UCLA, 650 C E Young Drive South, Los Angeles, CA 90095, USA
    J Am Coll Surg 203:421-5. 2006
    ..Incisional hernia is a potential complication of orthotopic liver transplantation (OLT), with various options for repair...
  59. ncbi request reprint Inhibition of chronic rejection by antibody induced vascular accommodation in fully allogeneic heart allografts
    Natalya V Semiletova
    The Dumont UCLA Transplant Center, Division of Liver and Pancreas Transplantation, Department of Surgery, David Geffen School of Medicine at UCLA, 10833 Le Conte Avenue, Los Angeles, CA 90095 7054, USA
    Transplantation 80:1535-40. 2005
    ..Here we investigate the protective effects of antibody binding to vascular endothelium in a fully mismatched allogeneic model of heart transplantation...
  60. ncbi request reprint Postresection hepatic failure: successful treatment with liver transplantation
    Yuichiro Otsuka
    Department of Surgery, Toho University School of Medicine, Tokyo, Japan
    Liver Transpl 13:672-9. 2007
    ..In conclusion, patients with low platelets, biopsy-proven cirrhosis, or those undergoing extended resection are at increased risk for PLF. OLT for PLF has significant morbidity but allows salvage of an otherwise fatal condition...

Research Grants2

  1. ADLDT: An Opportunity to Expand the National Donor Pool
    Ronald Busuttil; Fiscal Year: 2007
    ..Additionally, health utility index assessments and evaluation of health care resource utilization will be conducted. ..