R Ghadially

Summary

Affiliation: University of California
Country: USA

Publications

  1. doi request reprint CD133 is a marker for long-term repopulating murine epidermal stem cells
    Alexandra Charruyer
    Department of Dermatology, University of California, San Francisco, San Francisco, California, USA
    J Invest Dermatol 132:2522-33. 2012
  2. doi request reprint 25 years of epidermal stem cell research
    Ruby Ghadially
    Department of Dermatology and Epithelial Section, UCSF Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California, San Francisco, California 94121, USA
    J Invest Dermatol 132:797-810. 2012
  3. doi request reprint The role of stem and circulating cells in cancer metastasis
    Ruby Ghadially
    Department of Dermatology, Epithelial Pipeline of the Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California, San Francisco, California, USA
    J Surg Oncol 103:555-7. 2011
  4. ncbi request reprint The aged epidermal permeability barrier: basis for functional abnormalities
    Peter M Elias
    Department of Dermatology, University of California, San Francisco, USA
    Clin Geriatr Med 18:103-20, vii. 2002
  5. ncbi request reprint Imiquimod-induced interleukin-1 alpha stimulation improves barrier homeostasis in aged murine epidermis
    Chantel O Barland
    Department of Dermatology, University of California at San Francisco, and Veterans Affairs Medical Center, San Francisco, California 94121, USA
    J Invest Dermatol 122:330-6. 2004
  6. ncbi request reprint What's new in dermatology: epidermal stem cells
    A Charruyer
    Department of Dermatology and the Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California, San Francisco, CA 94121, USA
    G Ital Dermatol Venereol 146:57-67. 2011
  7. doi request reprint Transit-amplifying cell frequency and cell cycle kinetics are altered in aged epidermis
    Alexandra Charruyer
    Department of Dermatology, University of California, San Francisco, California 94121, USA
    J Invest Dermatol 129:2574-83. 2009
  8. doi request reprint Tiers of clonal organization in the epidermis: the epidermal proliferation unit revisited
    Lauren R Strachan
    Department of Dermatology, University of California San Francisco, San Francisco, CA 94143, USA
    Stem Cell Rev 4:149-57. 2008
  9. ncbi request reprint Epidermal stem cells
    Ruby Ghadially
    Associate Professor of Dermatology, University of California, San Francisco, California, USA
    Adv Dermatol 21:335-55. 2005
  10. pmc Limiting dilution analysis of murine epidermal stem cells using an in vivo regeneration assay
    Lauren R Strachan
    San Francisco VA Medical Center, University of California, San Francisco, CA, USA
    Methods Mol Biol 585:421-32. 2010

Research Grants

  1. Characterization of Epidermal Stem Cells
    Ruby Ghadially; Fiscal Year: 2009

Collaborators

  • Peter M Elias
  • Lauren R Strachan
  • Alexandra Charruyer
  • A Charruyer
  • Maria L Mancianti
  • Lili Yue
  • Chantel O Barland
  • Alexandra S Toth
  • Gary Cecchini
  • Chantal O Barland
  • Heike B Wessendorf
  • H Jeffrey Lawrence
  • Ying Lu
  • Barbara S Brown
  • Elizabeth Zettersten
  • Jianqin Ye

Detail Information

Publications10

  1. doi request reprint CD133 is a marker for long-term repopulating murine epidermal stem cells
    Alexandra Charruyer
    Department of Dermatology, University of California, San Francisco, San Francisco, California, USA
    J Invest Dermatol 132:2522-33. 2012
    ..6% were label-retaining cells. Thus, murine keratinocytes within the CD133(+) and CD133(+)ΔΨm(hi) populations contain EpiSCs that regenerate the epidermis for the long term, are self-renewing, multipotent, and label-retaining cells...
  2. doi request reprint 25 years of epidermal stem cell research
    Ruby Ghadially
    Department of Dermatology and Epithelial Section, UCSF Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California, San Francisco, California 94121, USA
    J Invest Dermatol 132:797-810. 2012
    ..However, our rapidly evolving understanding of epidermal stem cells has many potential uses that promise to translate into improved patient therapy...
  3. doi request reprint The role of stem and circulating cells in cancer metastasis
    Ruby Ghadially
    Department of Dermatology, Epithelial Pipeline of the Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California, San Francisco, California, USA
    J Surg Oncol 103:555-7. 2011
    ..Herein, we summarize current knowledge of melanoma-initiating cells and provide an update on recently gained knowledge regarding cancer stem cells and melanoma...
  4. ncbi request reprint The aged epidermal permeability barrier: basis for functional abnormalities
    Peter M Elias
    Department of Dermatology, University of California, San Francisco, USA
    Clin Geriatr Med 18:103-20, vii. 2002
    ..Barrier repair therapy can be effective in restoring normal function if a cholesterol-dominant mixture of the three key physiologic lipids, including ceramides and free fatty acids, is emphasized...
  5. ncbi request reprint Imiquimod-induced interleukin-1 alpha stimulation improves barrier homeostasis in aged murine epidermis
    Chantel O Barland
    Department of Dermatology, University of California at San Francisco, and Veterans Affairs Medical Center, San Francisco, California 94121, USA
    J Invest Dermatol 122:330-6. 2004
    ....
  6. ncbi request reprint What's new in dermatology: epidermal stem cells
    A Charruyer
    Department of Dermatology and the Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California, San Francisco, CA 94121, USA
    G Ital Dermatol Venereol 146:57-67. 2011
    ..This article discusses these recent advances in cutaneous stem cell biology...
  7. doi request reprint Transit-amplifying cell frequency and cell cycle kinetics are altered in aged epidermis
    Alexandra Charruyer
    Department of Dermatology, University of California, San Francisco, California 94121, USA
    J Invest Dermatol 129:2574-83. 2009
    ..Although longer cell cycle duration contributes to the decreased proliferative output from aged progenitors, the greater number of TA cells may be a compensatory mechanism tending to offset this deficit...
  8. doi request reprint Tiers of clonal organization in the epidermis: the epidermal proliferation unit revisited
    Lauren R Strachan
    Department of Dermatology, University of California San Francisco, San Francisco, CA 94143, USA
    Stem Cell Rev 4:149-57. 2008
    ....
  9. ncbi request reprint Epidermal stem cells
    Ruby Ghadially
    Associate Professor of Dermatology, University of California, San Francisco, California, USA
    Adv Dermatol 21:335-55. 2005
  10. pmc Limiting dilution analysis of murine epidermal stem cells using an in vivo regeneration assay
    Lauren R Strachan
    San Francisco VA Medical Center, University of California, San Francisco, CA, USA
    Methods Mol Biol 585:421-32. 2010
    ....

Research Grants5

  1. Characterization of Epidermal Stem Cells
    Ruby Ghadially; Fiscal Year: 2009
    ..Enriched populations of epidermal stem cells will aid stem cell-directed gene therapy, and when expanded will serve as a potential wound/burn healing therapy. ..