Genomes and Genes
Amin S Ghabrial
Affiliation: University of Pennsylvania
- A sweet spot in the FGFR signal transduction pathwayAmin S Ghabrial
Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
Sci Signal 5:pe1. 2012..Embryos lacking maternal and zygotic nst gene products show defective O-GlcNAcylation of a fibroblast growth factor receptor (FGFR)-specific adaptor protein, which impairs FGFR-dependent migration of mesodermal and tracheal cells...
- A systematic screen for tube morphogenesis and branching genes in the Drosophila tracheal systemAmin S Ghabrial
Department of Biochemistry, Stanford University School of Medicine, Stanford, CA, USA
PLoS Genet 7:e1002087. 2011....
- Social interactions among epithelial cells during tracheal branching morphogenesisAmin S Ghabrial
Howard Hughes Medical Institute, Department of Biochemistry, Stanford University School of Medicine, Stanford, California 94305 5307, USA
Nature 441:746-9. 2006..There may also be cooperation between budding cells, because in a mosaic epithelium, cells that cannot respond to the chemoattractant, or respond only poorly, allow other cells in the epithelium to move ahead of them...
- Drosophila talin and integrin genes are required for maintenance of tracheal terminal branches and luminal organizationBoaz P Levi
Department of Biochemistry and Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, CA 94305 5307, USA
Development 133:2383-93. 2006..Similar complexes may stabilize other tubular networks and may be targeted for inactivation during network remodeling events...
- Whacked and Rab35 polarize dynein-motor-complex-dependent seamless tube growthJodi Schottenfeld-Roames
Department of Cell and Developmental Biology, University of Pennsylvania School of Medicine, 421 Curie Boulevard, 1214 BRB II III, Philadelphia, Pennsylvania 19104, USA
Nat Cell Biol 14:386-93. 2012..Thus, vesicle trafficking has key roles in making and shaping seamless tubes...
- Tube continued: morphogenesis of the Drosophila tracheal systemJodi Schottenfeld
Department of Cell and Developmental Biology, 1214 BRBII III, 421 Curie Blvd, Philadelphia, PA 19104, USA
Curr Opin Cell Biol 22:633-9. 2010....
- Osmotic regulation of seamless tube growthJodi Schottenfeld-Roames
Department of Cell and Developmental Biology, University of Pennsylvania School of Medicine, Philadelphia, 19104, USA
Nat Cell Biol 15:137-9. 2013....
- Competition and morphogenesis in tip cell-mediated branching of tubular networksAmin S Ghabrial; Fiscal Year: 2010..This proposal aims to use Drosophila tracheal branching as a model to uncover the genetic and molecular mechanisms by which tip cells are selected and by which they lead outgrowth of new tubes. ..