Research Topics
Species | Jonathan C GewirtzSummaryAffiliation: University of Minnesota Country: USA Publications
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Detail Information
Publications
Effects of gestational iron deficiency on fear conditioning in juvenile and adult ratsJonathan C Gewirtz
Department of Psychology, University of Minnesota, 75 East River Road, Minneapolis, MN 55455, USA
Brain Res 1237:195-203. 2008....- Distinct profiles of anxiety and dysphoria during spontaneous withdrawal from acute morphine exposurePatrick E Rothwell
Department of Neuroscience, University of Minnesota, Minneapolis, MN 55455, USA
Neuropsychopharmacology 34:2285-95. 2009.... - Increased dopamine receptor activity in the nucleus accumbens shell ameliorates anxiety during drug withdrawalAnna K Radke
Graduate Program in Neuroscience, Minneapolis, MN, USA
Neuropsychopharmacology 37:2405-15. 2012..These results suggest that transient activation of the ventral tegmental area mesolimbic dopamine system triggers the expression of anxiety and aversion during withdrawal from multiple classes of abused drugs... 
Protracted manifestations of acute dependence after a single morphine exposurePatrick E Rothwell
Department of Neuroscience, University of Minnesota, 321 Church St SE, Minneapolis, MN 55455, USA
Psychopharmacology (Berl) 219:991-8. 2012..The physiological changes that underlie this state of acute dependence develop rapidly and can persist long after the end of chronic opiate exposure...
Effects of the NMDA receptor antagonist memantine on the expression and development of acute opiate dependence as assessed by withdrawal-potentiated startle and hyperalgesiaAndrew C Harris
Department of Psychology, University of Minnesota, 75 East River Road, Minneapolis, MN 55455, USA
Psychopharmacology (Berl) 196:649-60. 2008..While the N-methyl-D: -aspartate (NMDA) glutamate receptor has been strongly implicated in chronic opiate dependence, relatively few studies have examined the effects of NMDA receptor antagonists on withdrawal from acute opiate exposure...- Episodic withdrawal promotes psychomotor sensitization to morphinePatrick E Rothwell
Graduate Program in Neuroscience and Departments of Neuroscience and Psychology, University of Minnesota, Minneapolis, MN, USA
Neuropsychopharmacology 35:2579-89. 2010..Episodic withdrawal may have a pervasive role in many effects of intermittent drug exposure and contribute to the development of addiction... - Effects of chronic hypoxia in developing rats on dendritic morphology of the CA1 subarea of the hippocampus and on fear-potentiated startleLakshmi Raman
Department of Pediatrics, Hennepin County Medical Center, University of Minnesota, Minneapolis, MN 55415, USA
Brain Res 1190:167-74. 2008..These structural and functional alterations may contribute to the cognitive deficits seen in infants at risk for CH... - Role of corticosterone in trace and delay conditioned fear-potentiated startle in ratsMichael A Burman
Department of Psychology, University of New England, Biddeford, ME 04005, USA
Behav Neurosci 124:294-9. 2010..As hypothesized, only trace fear conditioning was impaired. This suggests that only fear conditioning tasks that are dependent on the dorsal hippocampus require HPA-axis activation in order to be learned... - Dissociable effects of hippocampus lesions on expression of fear and trace fear conditioning memories in ratsMichael A Burman
Department of Psychology, University of Minnesota, Minneapolis, Minnesota, USA
Hippocampus 16:103-13. 2006..These findings are consistent with evidence suggesting the neuroanatomical and functional segregation of the hippocampus into three zones along its septal-temporal axis... - Elevated startle during withdrawal from acute morphine: a model of opiate withdrawal and anxietyAndrew C Harris
Department of Psychology, University of Minnesota, 75 East River Road, Minneapolis, MN 55455, USA
Psychopharmacology (Berl) 171:140-7. 2004..This paradigm may be useful in the study of anxiety and the early mechanisms of drug dependence... - An anatomical basis for opponent process mechanisms of opiate withdrawalAnna K Radke
Graduate Program in Neuroscience, University of Minnesota, Minneapolis, Minnesota 55455, USA
J Neurosci 31:7533-9. 2011..Together, our results suggest that the emergence of anxiety during withdrawal from acute opiate exposure begins with activation of VTA mesolimbic dopamine circuitry, providing a mechanism for the opponent process view of withdrawal... - Potentiated startle as a measure of the negative affective consequences of repeated exposure to nicotine in ratsJeffrey M Engelmann
Department of Psychology, University of Minnesota, 75 East River Rd, Minneapolis, MN 55455, USA
Psychopharmacology (Berl) 207:13-25. 2009..Although anxiety is a clinical symptom of nicotine dependence, it is currently unknown whether anxiety-like behavior is elicited during the early stages of nicotine dependence in rodents... - HPA axis dysregulation following prenatal opiate exposure and postnatal withdrawalKathryn L Hamilton
Department of Psychology, University of Minnesota, Minneapolis, MN 55455, United States
Neurotoxicol Teratol 27:95-103. 2005..These results suggest that prenatal opiate exposure followed by postnatal withdrawal dysregulated the HPA axis response to stressors in the neonate and adult and differentially affected adult anxiety-like behavior in males and females... - Hippocampal activity, but not plasticity, is required for early consolidation of fear conditioning with a short trace intervalMichael A Burman
Department of Psychology, University of Minnesota, N218 Elliott Hall, 75 East River Rd, Minneapolis, MN 55455, USA
Eur J Neurosci 25:2483-90. 2007.... - Canonical TGF-beta signaling is required for the balance of excitatory/inhibitory transmission within the hippocampus and prepulse inhibition of acoustic startleMu Sun
Department of Genetics, Cell Biology and Development, Howard Hughes Medical Institute, University of Minnesota, Minnesota 55455, USA
J Neurosci 30:6025-35. 2010.... - Potentiated startle and hyperalgesia during withdrawal from acute morphine: effects of multiple opiate exposuresAndrew C Harris
Department of Psychology, University of Minnesota, 75 East River Road, Minneapolis, MN 55455, USA
Psychopharmacology (Berl) 176:266-73. 2004..These paradigms may be useful in examining the neural plasticity underlying the development of opiate dependence... - Acute opioid dependence: characterizing the early adaptations underlying drug withdrawalAndrew C Harris
Department of Psychology, University of Minnesota, 75 East River Road, Minneapolis, MN 55455, USA
Psychopharmacology (Berl) 178:353-66. 2005..Further study of acute dependence promises to lead to more effective treatments for opioid withdrawal and addiction... - Timing of fear expression in trace and delay conditioning measured by fear-potentiated startle in ratsMichael A Burman
University of Minnesota, Minneapolis, Minnesota 55455, USA
Learn Mem 11:205-12. 2004..These results are informative as to the possible role of neural structures, such as the hippocampus, in memory processes related to temporal information...