Jason R Gerstner

Summary

Affiliation: University of Pennsylvania
Country: USA

Publications

  1. pmc On the evolution of memory: a time for clocks
    Jason R Gerstner
    Center for Sleep and Circadian Neurobiology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA
    Front Mol Neurosci 5:23. 2012
  2. ncbi The nexus of Aβ, aging, and sleep
    Jason R Gerstner
    Center for Sleep and Circadian Neurobiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
    Sci Transl Med 4:150fs34. 2012
  3. pmc Time of day regulates subcellular trafficking, tripartite synaptic localization, and polyadenylation of the astrocytic Fabp7 mRNA
    Jason R Gerstner
    Center for Sleep and Circadian Neurobiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
    J Neurosci 32:1383-94. 2012
  4. pmc Fatty-acid binding proteins modulate sleep and enhance long-term memory consolidation in Drosophila
    Jason R Gerstner
    Department of Genetics, University of Wisconsin Madison, Madison, Wisconsin, United States of America
    PLoS ONE 6:e15890. 2011
  5. pmc Brain fatty acid binding protein (Fabp7) is diurnally regulated in astrocytes and hippocampal granule cell precursors in adult rodent brain
    Jason R Gerstner
    Neuroscience Training Program, University of Wisconsin Madison, Madison, Wisconsin, USA
    PLoS ONE 3:e1631. 2008
  6. pmc Sleep symptoms associated with intake of specific dietary nutrients
    Michael A Grandner
    Center for Sleep and Circadian Neurobiology, University of Pennsylvania, Philadelphia, PA, USA Division of Sleep Medicine, Department of Medicine, University of Pennsylvania, Philadelphia, PA, USA
    J Sleep Res 23:22-34. 2014
  7. pmc Regulation of neural specification from human embryonic stem cells by BMP and FGF
    Timothy M LaVaute
    Neuroscience Training Program, School of Medicine, University of Wisconsin Madison, Madison, Wisconsin 53705, USA
    Stem Cells 27:1741-9. 2009
  8. ncbi Circadian rhythms and memory formation
    Jason R Gerstner
    Department of Genetics, University of Wisconsin Madison, 3476 Genetics and Biotechnology, 425 Henry Mall, Madison, Wisconsin 53706, USA
    Nat Rev Neurosci 11:577-88. 2010
  9. ncbi The zinc-binding protein chordc1 undergoes complex diurnal changes in mRNA expression during mouse brain development
    Jason R Gerstner
    Neuroscience Training Program and Department of Psychiatry, University of Wisconsin Madison, Madison, WI 53719, USA
    Neurochem Res 32:241-50. 2007
  10. doi Cycling behavior and memory formation
    Jason R Gerstner
    Department of Genetics, University of Wisconsin Madison, Madison, Wisconsin 53706, USA
    J Neurosci 29:12824-30. 2009

Collaborators

Detail Information

Publications12

  1. pmc On the evolution of memory: a time for clocks
    Jason R Gerstner
    Center for Sleep and Circadian Neurobiology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA
    Front Mol Neurosci 5:23. 2012
    ..Therefore, this notion predicts a model that LTP and metaplasticity may exist in neural circuits of other species, through phylogenetically conserved pathways, leading to several testable hypotheses...
  2. ncbi The nexus of Aβ, aging, and sleep
    Jason R Gerstner
    Center for Sleep and Circadian Neurobiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
    Sci Transl Med 4:150fs34. 2012
    ..Roh et al. report a positive feedback loop between sleep-wake irregularities and aggregation of β-amyloid peptide, suggesting that sleep alterations could be an early event in Alzheimer's disease...
  3. pmc Time of day regulates subcellular trafficking, tripartite synaptic localization, and polyadenylation of the astrocytic Fabp7 mRNA
    Jason R Gerstner
    Center for Sleep and Circadian Neurobiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
    J Neurosci 32:1383-94. 2012
    ..These results implicate circadian, sleep, and/or metabolic control of CPEB-mediated subcellular trafficking and localized translation of Fabp7 mRNA in the tripartite synapse of mammalian brain...
  4. pmc Fatty-acid binding proteins modulate sleep and enhance long-term memory consolidation in Drosophila
    Jason R Gerstner
    Department of Genetics, University of Wisconsin Madison, Madison, Wisconsin, United States of America
    PLoS ONE 6:e15890. 2011
    ....
  5. pmc Brain fatty acid binding protein (Fabp7) is diurnally regulated in astrocytes and hippocampal granule cell precursors in adult rodent brain
    Jason R Gerstner
    Neuroscience Training Program, University of Wisconsin Madison, Madison, Wisconsin, USA
    PLoS ONE 3:e1631. 2008
    ..Of clock or clock-regulated genes, the synchronized, global cycling pattern of Fabp7 expression is unique and implicates glial cells in the response or modulation of activity and/or circadian rhythms...
  6. pmc Sleep symptoms associated with intake of specific dietary nutrients
    Michael A Grandner
    Center for Sleep and Circadian Neurobiology, University of Pennsylvania, Philadelphia, PA, USA Division of Sleep Medicine, Department of Medicine, University of Pennsylvania, Philadelphia, PA, USA
    J Sleep Res 23:22-34. 2014
    ..04), potassium (OR = 0.70) and water (OR = 0.97). These results suggest novel associations between sleep symptoms and diet/metabolism, potentially explaining associations between sleep and cardiometabolic diseases. ..
  7. pmc Regulation of neural specification from human embryonic stem cells by BMP and FGF
    Timothy M LaVaute
    Neuroscience Training Program, School of Medicine, University of Wisconsin Madison, Madison, Wisconsin 53705, USA
    Stem Cells 27:1741-9. 2009
    ..Blocking FGF signaling inhibited neural induction, but did not alter the phosphorylation of the linker region of Smad1, suggesting that FGF enhances human neural specification independently of BMP signaling...
  8. ncbi Circadian rhythms and memory formation
    Jason R Gerstner
    Department of Genetics, University of Wisconsin Madison, 3476 Genetics and Biotechnology, 425 Henry Mall, Madison, Wisconsin 53706, USA
    Nat Rev Neurosci 11:577-88. 2010
    ..Together, these studies suggest that common mechanisms underlie circadian rhythmicity and long-term memory formation...
  9. ncbi The zinc-binding protein chordc1 undergoes complex diurnal changes in mRNA expression during mouse brain development
    Jason R Gerstner
    Neuroscience Training Program and Department of Psychiatry, University of Wisconsin Madison, Madison, WI 53719, USA
    Neurochem Res 32:241-50. 2007
    ..These results suggest that Chordc1 mRNA is under complex and widespread transcriptional regulation during development and implicate Chordc1 in circadian and/or homeostatic mechanisms in mammalian brain...
  10. doi Cycling behavior and memory formation
    Jason R Gerstner
    Department of Genetics, University of Wisconsin Madison, Madison, Wisconsin 53706, USA
    J Neurosci 29:12824-30. 2009
    ..Conservation of a functional relationship between circadian rhythms with learning and memory formation across species provides a critical framework for future analysis of molecular mechanisms underlying complex behavior...
  11. pmc Dietary nutrients associated with short and long sleep duration. Data from a nationally representative sample
    Michael A Grandner
    Center for Sleep and Circadian Neurobiology, University of Pennsylvania, 3624 Market Street, Suite 205, Philadelphia, PA 19104, USA
    Appetite 64:71-80. 2013
    ..In addition, these data may help us better understand the complex relationship between diet and sleep and the potential role of diet in the relationship between sleep and obesity and other cardiometabolic risks...
  12. pmc dCREB2-mediated enhancement of memory formation
    Thomas C Tubon
    Department of Genetics and Neurology, Institute on Aging, Neuroscience Training Program, Wisconsin Institute of Medical Research, University of Wisconsin Madison, Madison, Wisconsin 53706, USA
    J Neurosci 33:7475-87. 2013
    ..Our results reaffirm that overexpression of a dCREB2 activator can enhance memory formation and illustrate the complexity of this behavioral enhancement...