J B German

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi Personal metabolomics as a next generation nutritional assessment
    J Bruce German
    Nestle Research Center, Lausanne 26, Switzerland University of California, Davis, CA 95616, USA
    J Nutr 133:4260-6. 2003
  2. ncbi Understanding milk's bioactive components: a goal for the genomics toolbox
    Robert E Ward
    Department of Food Science and Technology, University of California Davis, Davis, CA 95616, USA
    J Nutr 134:962S-7S. 2004
  3. ncbi Saturated fats: what dietary intake?
    J Bruce German
    Department of Food Science and Technology, University of California, 1 Shields Avenue, Davis, CA 95616, USA
    Am J Clin Nutr 80:550-9. 2004
  4. ncbi Metabolomics in practice: emerging knowledge to guide future dietetic advice toward individualized health
    J Bruce German
    Department of Food Science and Technology, University of California, Davis, 95616, USA
    J Am Diet Assoc 105:1425-32. 2005
  5. ncbi Composition, structure and absorption of milk lipids: a source of energy, fat-soluble nutrients and bioactive molecules
    J Bruce German
    Department of Food Science and Technology, University of California, Davis, CA, 95616, USA
    Crit Rev Food Sci Nutr 46:57-92. 2006
  6. ncbi Dietary fat and not calcium supplementation or dairy product consumption is associated with changes in anthropometrics during a randomized, placebo-controlled energy-restriction trial
    Jennifer T Smilowitz
    USDA, ARS, Western Human Nutrition Research Center, Davis, CA 95616, USA
    Nutr Metab (Lond) 8:67. 2011
  7. ncbi The bovine lactation genome: insights into the evolution of mammalian milk
    Danielle G Lemay
    Department of Food Science and Technology, University of California Davis, One Shields Avenue, Davis, CA 95616, USA
    Genome Biol 10:R43. 2009
  8. ncbi Gene regulatory networks in lactation: identification of global principles using bioinformatics
    Danielle G Lemay
    Department of Food Science and Technology, University of California, One Shields Ave, Davis, CA 95616, USA
    BMC Syst Biol 1:56. 2007
  9. ncbi Metabolomics and individual metabolic assessment: the next great challenge for nutrition
    J B German
    Department of Food Science, University of California, Davis, CA 95616, USA
    J Nutr 132:2486-7. 2002
  10. ncbi Saturated fats: a perspective from lactation and milk composition
    J Bruce German
    Department of Food Science and Technology, University of California, Davis, CA 95616, USA
    Lipids 45:915-23. 2010

Detail Information

Publications72

  1. ncbi Personal metabolomics as a next generation nutritional assessment
    J Bruce German
    Nestle Research Center, Lausanne 26, Switzerland University of California, Davis, CA 95616, USA
    J Nutr 133:4260-6. 2003
    ..It is time for these two fields to address a common problem, metabolic health, with coordinated solutions...
  2. ncbi Understanding milk's bioactive components: a goal for the genomics toolbox
    Robert E Ward
    Department of Food Science and Technology, University of California Davis, Davis, CA 95616, USA
    J Nutr 134:962S-7S. 2004
    ..Understanding structures and regulation will guide scientists to new benefits and ultimately to the knowledge to build a new generation of delicious foods that genuinely deliver on the promise of safety and maintenance of optimal health...
  3. ncbi Saturated fats: what dietary intake?
    J Bruce German
    Department of Food Science and Technology, University of California, 1 Shields Avenue, Davis, CA 95616, USA
    Am J Clin Nutr 80:550-9. 2004
    ..more individualized dietary recommendations, should the steps to decrease saturated fatty acids to as low as agriculturally possible not wait until evidence clearly indicates which amounts and types of saturated fatty acids are optimal?..
  4. ncbi Metabolomics in practice: emerging knowledge to guide future dietetic advice toward individualized health
    J Bruce German
    Department of Food Science and Technology, University of California, Davis, 95616, USA
    J Am Diet Assoc 105:1425-32. 2005
    ....
  5. ncbi Composition, structure and absorption of milk lipids: a source of energy, fat-soluble nutrients and bioactive molecules
    J Bruce German
    Department of Food Science and Technology, University of California, Davis, CA, 95616, USA
    Crit Rev Food Sci Nutr 46:57-92. 2006
    ....
  6. ncbi Dietary fat and not calcium supplementation or dairy product consumption is associated with changes in anthropometrics during a randomized, placebo-controlled energy-restriction trial
    Jennifer T Smilowitz
    USDA, ARS, Western Human Nutrition Research Center, Davis, CA 95616, USA
    Nutr Metab (Lond) 8:67. 2011
    ..However, weight loss interventions including dietary calcium or dairy product consumption have not reported changes in lipid metabolism measured by the plasma lipidome...
  7. ncbi The bovine lactation genome: insights into the evolution of mammalian milk
    Danielle G Lemay
    Department of Food Science and Technology, University of California Davis, One Shields Avenue, Davis, CA 95616, USA
    Genome Biol 10:R43. 2009
    ..The newly assembled Bos taurus genome sequence enables the linkage of bovine milk and lactation data with other mammalian genomes...
  8. ncbi Gene regulatory networks in lactation: identification of global principles using bioinformatics
    Danielle G Lemay
    Department of Food Science and Technology, University of California, One Shields Ave, Davis, CA 95616, USA
    BMC Syst Biol 1:56. 2007
    ..The molecular events underlying mammary development during pregnancy, lactation, and involution are incompletely understood...
  9. ncbi Metabolomics and individual metabolic assessment: the next great challenge for nutrition
    J B German
    Department of Food Science, University of California, Davis, CA 95616, USA
    J Nutr 132:2486-7. 2002
  10. ncbi Saturated fats: a perspective from lactation and milk composition
    J Bruce German
    Department of Food Science and Technology, University of California, Davis, CA 95616, USA
    Lipids 45:915-23. 2010
    ..Is it possible that evolution of the mammary gland reveals benefits to saturated fatty acids that current recommendations do not consider?..
  11. ncbi Genomics and metabolomics as markers for the interaction of diet and health: lessons from lipids
    J Bruce German
    Department of Food Science and Technology, University of California, Davis, CA 95616, USA
    J Nutr 133:2078S-2083S. 2003
    ..The need to document the lack of an adverse effect of a food or drug on physiology necessitates a global, i.e. metabolomic approach...
  12. ncbi Dietary lipids from an evolutionary perspective: sources, structures and functions
    J Bruce German
    Department of Food Science and Technology, University of California Davis, CA 95616, USA
    Matern Child Nutr 7:2-16. 2011
    ..The complex composition of human milk lipids implies that diets with a diversity of fatty acids in complex lipid forms and structures is more beneficial than a narrow range of any particular group of fatty acids...
  13. ncbi Lipidomics and lipid profiling in metabolomics
    J Bruce German
    Department of Food Science and Technology, University of California, Davis, CA 95616, USA
    Curr Opin Lipidol 18:66-71. 2007
    ..Lipids studied using metabolomic approaches - lipidomics - are an ideal subject for metabolomic measurements...
  14. ncbi A reappraisal of the impact of dairy foods and milk fat on cardiovascular disease risk
    J Bruce German
    Department of Food Science and Technology, University of California, Davis, CA, 95616, USA
    Eur J Nutr 48:191-203. 2009
    ..A conference of scientists from different perspectives of dietary fat and health was convened in order to consider the scientific basis for these recommendations...
  15. ncbi The health benefits of wine
    J B German
    Department of Food Science, University of California at Davis, Davis, California 95616, USA
    Annu Rev Nutr 20:561-93. 2000
    ..Future research must address specific mechanisms both of alcohol and of polyphenolic action and develop biomarkers of their role in disease prevention in individuals...
  16. ncbi Bioactive components in milk
    J Bruce German
    Department of Food Science and Technology, University of California, Davis 95616, USA
    Curr Opin Clin Nutr Metab Care 5:653-8. 2002
    ....
  17. ncbi Unique phospholipid metabolism in mouse heart in response to dietary docosahexaenoic or alpha-linolenic acids
    S M Watkins
    Department of Food Science and Technology, 1 Shields Ave, University of California at Davis, Davis, CA 95616, USA
    Lipids 36:247-54. 2001
    ..The increased mass of PC was coincident with a decrease in the mass of phosphatidylethanolamine, suggesting that 22:6n-3 induced PC synthesis by increasing phosphatidylethanolamine-N-methyltransferase activity in the heart...
  18. ncbi Bovine milk glycome
    N Tao
    Department of Chemistry and Biochemistry, School of Medicine, University of California, Davis 95616, USA
    J Dairy Sci 91:3768-78. 2008
    ..Sialic acid residues include both N-acetyl and N-glycolylneuraminic acid, although the former is significantly more abundant...
  19. ncbi Neutral and acidic oligosaccharides in Holstein-Friesian colostrum during the first 3 days of lactation measured by high performance liquid chromatography on a microfluidic chip and time-of-flight mass spectrometry
    D Barile
    Department of Food Science and Technology, University of California, Davis 95616, USA
    J Dairy Sci 93:3940-9. 2010
    ..This investigation revealed that colostrum milk from Holstein-Friesian cows is a rich source of neutral and acidic OS for the food and pharmaceutical industries...
  20. ncbi Individual metabolism should guide agriculture toward foods for improved health and nutrition
    S M Watkins
    Department of Food Science and Technology, University of California, Davis, USA
    Am J Clin Nutr 74:283-6. 2001
    ....
  21. ncbi Fatty acid and triglyceride composition of milk fat from lactating Holstein cows in response to supplemental canola oil
    E J DePeters
    Department of Animal Science, University of California, Davis 95616 8521, USA
    J Dairy Sci 84:929-36. 2001
    ..Triglyceride composition reported as carbon number was altered by canola oil. Triglycerides in carbon number C50, C52, and C54 were increased while C32, C34, and C36 were decreased...
  22. ncbi Metabolomics for assessment of nutritional status
    Angela M Zivkovic
    Department of Food Science and Technology, University of California, Davis, CA 95616, USA
    Curr Opin Clin Nutr Metab Care 12:501-7. 2009
    ..The basic toolset, targets and knowledge are all being developed in the emerging field of metabolomics, yet important knowledge and technology gaps will need to be addressed in order to bring such assessment to practice...
  23. ncbi Body composition of inactivated growth hormone (oMt1a-oGH) transgenic mice: generation of an obese phenotype
    A M Oberbauer
    Department of Animal Science, University of California, Davis, USA
    Growth Dev Aging 61:169-79. 1997
    ..The oMt1a-oGH mouse provides a novel model of induced obesity in response to inactivation of a GH-transgene by the withdrawal of the transgene stimulus...
  24. ncbi Growth hormone enhances arachidonic acid metabolites in a growth hormone transgenic mouse
    A M Oberbauer
    Department of Animal Science, University of California, Davis, CA 95616, USA
    Lipids 46:495-504. 2011
    ....
  25. ncbi Sodium butyrate upregulates Kupffer cell PGE2 production and modulates immune function
    R Perez
    Department of Surgery, University of California, Davis, Sacramento, California 95817, USA
    J Surg Res 78:1-6. 1998
    ..Thus, butyrate may be a useful immunoregulatory agent in organ transplantation protocols which seek to enhance transcription of immunosuppressive molecules...
  26. ncbi Kupffer cell-mediated lymphocyte apoptosis: a PGE2-dependent mechanism of portal venous transfusion-induced immunosuppression?
    R Perez
    Department of Surgery, University of California, Davis, Sacramento, California 95817, USA
    J Surg Res 78:37-41. 1998
    ..Additionally, enhanced lymphocyte apoptosis, a process known to be macrophage dependent and facilitated by PGE2, is postulated as a possible mechanism of PVT-induced, Kupffer cell-mediated immunosuppression...
  27. ncbi Oxidative stability of fish and algae oils containing long-chain polyunsaturated fatty acids in bulk and in oil-in-water emulsions
    Edwin N Frankel
    Department of Food Science and Technology, University of California, Davis, California 95616, USA
    J Agric Food Chem 50:2094-9. 2002
    ..Therefore, to be effective as a metal chelator, EDTA must be added at molar concentrations higher than that of iron to inhibit oxidation of foods containing long-chain PUFA from either fish or algae and fortified with iron...
  28. ncbi Comparative review of diets for the metabolic syndrome: implications for nonalcoholic fatty liver disease
    Angela M Zivkovic
    Department of Food Science and Technology, University of California, Davis, CA 95616, USA
    Am J Clin Nutr 86:285-300. 2007
    ..The premises, effects, barriers, and issues related to current dietary guidelines and specific diets are discussed, and the question, "Will it work for the pathogenesis of NAFLD and NASH? ", is addressed...
  29. ncbi Lipid metabolism predicts changes in body composition during energy restriction in overweight humans
    Jennifer T Smilowitz
    Department of Food Science and Technology, University of California, Davis, CA 95616, USA
    J Nutr 139:222-9. 2009
    ..Thus, circulating lipids reflect lipid metabolism in relation to changes in body composition...
  30. ncbi Amelioration of tacrolimus-induced nephrotoxicity in rats using juniper oil
    Lavjay Butani
    Section of Pediatric Nephrology, University of California, Davis Medical Center, Sacramento, CA 95817, USA
    Transplantation 76:306-11. 2003
    ..The purpose of our study was to evaluate whether altering the prostanoid profile using juniper oil (JO) would afford renoprotection in rats treated with tacrolimus...
  31. ncbi Effect of estrogen and 2,3,7,8-tetrachlorodibenzo-rho-dioxin (TCDD) on plasma fatty acids of immature male chickens (Gallus domesticus)
    Beckye J Stanton
    Lasley Laboratory, Center for Health and the Environment, University of California, One Shields Ave, Davis, CA 95616, USA
    Comp Biochem Physiol C Toxicol Pharmacol 132:129-42. 2002
    ..Overall, TCDD treatment alone increased plasma lipids, possibly as a result of decreased clearance or utilization; whereas estrogen plus TCDD treatment antagonized estrogen-induced increases in 22:6n3 but did not cause hyperlipidemia...
  32. ncbi Size-dependent lipid content in human milk fat globules
    Nurit Argov
    Department of Food Science and Technology, University of California Davis, 1 Shields Avenue, Davis, California 95616, USA
    J Agric Food Chem 56:7446-50. 2008
    ..In addition, large portions of the HMFGs are secreted into milk conspicuously not for fat delivery. Thus, small HMFGs may offer novel metabolic and nutritional functions...
  33. ncbi Pretransplant free fatty acids (FFA) and allograft survival in renal transplantation
    Aaron C Baker
    Department of Surgery, University of California Davis Medical Center, Sacramento, California 95817, USA
    J Surg Res 164:182-7. 2010
    ..We hypothesize that elevated pretransplant free fatty acids (FFA) levels may be associated with prolonged survival of kidney transplants...
  34. ncbi Dietary intake of polyunsaturated fatty acids among breast-feeding and non-breast-feeding 24- to 48-month-old children in Bangladesh
    Elizabeth A Yakes
    Graduate Group in Epidemiology
    J Pediatr Gastroenterol Nutr 52:351-9. 2011
    ..The aim of the study was to assess the adequacy of polyunsaturated fatty acid intake by rural Bangladeshi children 24 to 48 months old in relation to their breast-feeding status...
  35. ncbi Effect of dietary omega-3 fatty acids on red blood cell lipid composition and plasma metabolites in the cockatiel, Nymphicus hollandicus
    C R Heinze
    Department of Animal Science, University of California, Davis, Davis 95616, USA
    J Anim Sci 90:3068-79. 2012
    ..Thus, dietary modification of psittacine diets with long chain n-3 PUFA from fish oil appears safe and may be beneficial to these long-lived companion birds...
  36. ncbi Variations in bovine milk oligosaccharides during early and middle lactation stages analyzed by high-performance liquid chromatography-chip/mass spectrometry
    N Tao
    Department of Chemistry and Biochemistry School of Medicine, University of California, Davis 95616, USA
    J Dairy Sci 92:2991-3001. 2009
    ..The total concentrations dropped rapidly in the first several days of lactation. Moreover, the anionic oligosaccharides (including N-glycolylneuraminic acid) decreased more rapidly compared with the neutral oligosaccharides...
  37. ncbi The genome sequence of Bifidobacterium longum subsp. infantis reveals adaptations for milk utilization within the infant microbiome
    D A Sela
    Microbiology Graduate Group, Robert Mondavi Institute for Wine and Food Sciences, University of California, Davis, CA 95616, USA
    Proc Natl Acad Sci U S A 105:18964-9. 2008
    ..Finally, conservation of gene clusters in multiple isolates corroborates the genomic mechanism underlying milk utilization for this infant-associated phylotype...
  38. ncbi Plasma omega 3 polyunsaturated fatty acid status and monounsaturated fatty acids are altered by chronic social stress and predict endocrine responses to acute stress in titi monkeys
    K D Laugero
    Western Human Nutrition Research Center ARS USDA, Davis, CA 95616, USA
    Prostaglandins Leukot Essent Fatty Acids 84:71-8. 2011
    ..Our results are consistent with previously reported FA profiles in stress-related psychopathology and suggest that compositional changes of specific lipid FAs may form new functional markers of chronic psychological stress...
  39. ncbi Glycoprotein expression in human milk during lactation
    John W Froehlich
    Department of Chemistry, University of California, Davis, California 95616, USA
    J Agric Food Chem 58:6440-8. 2010
    ..Variations in expression or glycosylation levels are also demonstrated for several other abundant whey proteins, including tenascin, bile salt-stimulated lipase, xanthine dehydrogenase, and mannose receptor...
  40. ncbi Plasma fatty acid profiles in autism: a case-control study
    M M Wiest
    Division of Epidemiology, Department of Public Health, University of California, Davis, CA 95616, USA
    Prostaglandins Leukot Essent Fatty Acids 80:221-7. 2009
    ....
  41. ncbi Alteration of the fatty acid substrate specificity of lysophosphatidate acyltransferase by site-directed mutagenesis
    L Z Morand
    Department of Food Science and Technology, University of California, Davis 95616, USA
    Biochem Biophys Res Commun 244:79-84. 1998
    ..A change from threonine-122 to alanine increased the substrate specificity in vitro for oleoyl-CoA and linoleoyl-CoA; whereas a change to leucine increased the substrate specificity for lignoceroyl-CoA...
  42. ncbi Method for the identification of lipid classes based on referenced Kendrick mass analysis
    Larry A Lerno
    Department of Chemistry, University of California, One Shields Avenue, Davis, California 95616, USA
    Anal Chem 82:4236-45. 2010
    ..As a real world example the lipid extract from bovine milk was analyzed using both accurate mass measurements and the RKMD method...
  43. ncbi A strategy for annotating the human milk glycome
    Milady R Ninonuevo
    Department of Chemistry and Biochemistry (School of Medicine, University of California, Davis, California 95616, USA
    J Agric Food Chem 54:7471-80. 2006
    ..HPLC-Chip/MS profiling provides a method for routinely identifying milk oligosaccharides. Tandem MS in combination with exoglycosidase digestion provides unambiguous differentiation of structural isomers...
  44. ncbi Chocolate procyanidins decrease the leukotriene-prostacyclin ratio in humans and human aortic endothelial cells
    D D Schramm
    Department of Nutrition, University of California, Davis 95616 8669, USA
    Am J Clin Nutr 73:36-40. 2001
    ..Polyphenolic phytochemicals inhibit vascular and inflammatory processes that contribute to disease. These effects are hypothesized to result from polyphenol-mediated alterations in cellular eicosanoid synthesis...
  45. ncbi Interaction of estrogen and 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) with hepatic fatty acid synthesis and metabolism of male chickens (Gallus domesticus)
    B Stanton
    Institute of Toxicology and Environmental Health ITEH, University of California Davis, One Shields Ave, 95616, Davis, CA, USA
    Comp Biochem Physiol C Toxicol Pharmacol 129:137-50. 2001
    ..In cholesterol esters, all three treatments decreased concentrations of total fatty acids, saturated fatty acids, and Delta9 desaturase products compared to the control group...
  46. ncbi Glycoprofiling of bifidobacterial consumption of human milk oligosaccharides demonstrates strain specific, preferential consumption of small chain glycans secreted in early human lactation
    Riccardo G LoCascio
    Department of Viticulture and Enology, University of California Davis, Davis, California 95616, USA
    J Agric Food Chem 55:8914-9. 2007
    ....
  47. ncbi Quantitative lipid analysis and life span of the fat-3 mutant of Caenorhabditis elegans
    S Luke Hillyard
    Department of Food Science and Technology, University of California, Davis, California 95616, USA
    J Agric Food Chem 57:3389-96. 2009
    ..The results show a beneficial effect of these molecules on the life span of C. elegans and will aid in the elucidation of the underlying causes of PUFA deficiency in the simple animal C. elegans as well as in humans...
  48. ncbi Daily variations in oligosaccharides of human milk determined by microfluidic chips and mass spectrometry
    Milady R Ninonuevo
    Department of Chemistry, University of California, Davis, CA 95616, USA
    J Agric Food Chem 56:618-26. 2008
    ..Comparison of HPLC-Chip/TOF-MS oligosaccharides profiles revealed heterogeneity among multiple individuals with no significant variations at different stages of lactation within individual donors...
  49. ncbi Dairy proteins and the response to pneumovax in senior citizens: a randomized, double-blind, placebo-controlled pilot study
    Samara L Freeman
    Department of Food Science and Technology, University of California, Davis, California 95616, USA
    Ann N Y Acad Sci 1190:97-103. 2010
    ..Whey protein supplementation is a promising supplement to stimulate the immune response to vaccine in senior citizens and possibly to counteract immunosenescence while larger studies are warranted...
  50. ncbi Alteration in plasma testosterone levels in male mice lacking soluble epoxide hydrolase
    Ayala Luria
    Departmentsof Entomology, University of California, Davis, CA 95616, USA
    Am J Physiol Endocrinol Metab 297:E375-83. 2009
    ....
  51. ncbi Consumption of human milk oligosaccharides by gut-related microbes
    Angela Marcobal
    Department of Viticulture and Enology, University of California, Davis, California 95616, USA
    J Agric Food Chem 58:5334-40. 2010
    ..These results provide insight on how human milk oligosaccharides shape the infant intestinal microbiota...
  52. ncbi Structural determination and daily variations of porcine milk oligosaccharides
    Nannan Tao
    Department of Chemistry and Biochemistry School of Medicine, University of California, Davis, California 95616, USA
    J Agric Food Chem 58:4653-9. 2010
    ..In summary, porcine milk contains both acidic (sialylated) and neutral OS, but sialic acid containing OS predominate throughout lactation...
  53. ncbi In vitro fermentation of breast milk oligosaccharides by Bifidobacterium infantis and Lactobacillus gasseri
    Robert E Ward
    Department of Food Science and Technology, University of California, Davis, CA 95616, USA
    Appl Environ Microbiol 72:4497-9. 2006
    ..Our results support the hypothesis that HMO selectively amplify bacterial populations in the infant intestine...
  54. ncbi Methods for the quantitation of human milk oligosaccharides in bacterial fermentation by mass spectrometry
    Milady R Ninonuevo
    Department of Chemistry and Biochemistry, School of Medicine, University of California, Davis, CA 95616, USA
    Anal Biochem 361:15-23. 2007
    ....
  55. ncbi In vitro fermentability of human milk oligosaccharides by several strains of bifidobacteria
    Robert E Ward
    Department of Food Science and Technology, University of California, Davis, CA 95616, USA
    Mol Nutr Food Res 51:1398-405. 2007
    ..These results suggest that as a potential prebiotic, HMO may selectively promote the growth of certain bifidobacteria strains, and their catabolism may result in free monosaccharides in the colonic lumen...
  56. ncbi Building the bridges to bioinformatics in nutrition research
    Danielle G Lemay
    Department of Food Science and Technology, University of California, Davis, CA 95616, USA
    Am J Clin Nutr 86:1261-9. 2007
    ....
  57. ncbi Development of an annotated library of neutral human milk oligosaccharides
    Shuai Wu
    Department of Chemistry, University of California, Davis, California 95616, USA
    J Proteome Res 9:4138-51. 2010
    ..A library with 45 neutral OS structures has been constructed. The structures include information regarding the epitopes such as Lewis type, as well as information regarding the secretor status...
  58. ncbi Human milk oligosaccharides: evolution, structures and bioselectivity as substrates for intestinal bacteria
    J Bruce German
    Department of Nutrition, University of California, Davis, CA, USA
    Nestle Nutr Workshop Ser Pediatr Program 62:205-18; discussion 218-22. 2008
    ..The goal of ongoing research is to assign specific functions to the combined oligosaccharide-bacteria-host interactions that emerged from this evolutionary pressure...
  59. ncbi Analytical performance of immobilized pronase for glycopeptide footprinting and implications for surpassing reductionist glycoproteomics
    Eric D Dodds
    Department of Chemistry, University of California, Davis, California 95616, USA
    J Proteome Res 8:502-12. 2009
    ....
  60. ncbi Lipid metabolome-wide effects of the PPARgamma agonist rosiglitazone
    Steven M Watkins
    Lipomics Technologies, Inc, 2545 Boatman Ave, West Sacramento, CA 95691, USA
    J Lipid Res 43:1809-17. 2002
    ..Because many of the effects of rosiglitazone on tissue metabolism were reflected in the plasma lipid metabolome, metabolomics has excellent potential for developing clinical assessments of metabolic response to drug therapy...
  61. ncbi Effects of natural phenolic compounds on the antioxidant activity of lactoferrin in liposomes and oil-in-water emulsions
    Isabel Medina
    Instituto de Investigaciones Marinas del CSIC, Eduardo Cabello 6, E 36208 Vigo, Spain
    J Agric Food Chem 50:2392-9. 2002
    ..The highest synergistic effects were observed for the phenolic extracts rich in polyphenols of extra-virgin olive oils and lactoferrin. This synergistic effect was higher in liposomes than in emulsions...
  62. ncbi Unraveling lipid metabolism with microarrays: effects of arachidonate and docosahexaenoate acid on murine hepatic and hippocampal gene expression
    Alvin Berger
    Metabolic and Genomic Regulation, Nestle Research Center, Vers-chez-les-Blanc, CH-1000 Lausanne 26, Switzerland
    Genome Biol 3:PREPRINT0004. 2002
    ..Novel hippocampal PUFA-molecular targets suggest that PUFA transcriptionally regulated genes with roles in appetite and learning...
  63. ncbi Metabolomics and biochemical profiling in drug discovery and development
    Steven M Watkins
    Lipomics Technologies Inc, West Sacramento, CA 95691, USA
    Curr Opin Mol Ther 4:224-8. 2002
    ..Metabolomics is useful in virtually all aspects of biomedical research, and it is likely to evolve into an essential component of the drug discovery and development process...
  64. ncbi Toward the implementation of metabolomic assessments of human health and nutrition
    Steven M Watkins
    Lipomics Technologies, 2545 Boatman Avenue, West Sacramento, CA 95691, USA
    Curr Opin Biotechnol 13:512-6. 2002
    ....
  65. ncbi PASSCLAIM - Diet-related cardiovascular disease
    Ronald P Mensink
    Maastricht University, Department of Human Biology, P. O. Box 616, 6200 MD Maastricht, The Netherlands
    Eur J Nutr 42:I6-27. 2003
    ..Therefore, studies to further validate generic predictors for the CVD risk should be initiated...
  66. ncbi An integrative metabolism approach identifies stearoyl-CoA desaturase as a target for an arachidonate-enriched diet
    David M Mutch
    , Vers-chez-les-Blanc, Lausanne, Switzerland
    FASEB J 19:599-601. 2005
    ....
  67. ncbi Genetic dietetics: nutrigenomics and the future of dietetics practice
    J Bruce German
    J Am Diet Assoc 105:530-1. 2005
  68. ncbi Characterization of proteomic and metabolomic responses to dietary factors and supplements
    John Astle
    University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390, USA
    J Nutr 137:2787-93. 2007
    ..Likewise, an overview of the methodologies used in metabolomic profiling of natural products was presented, and an illustration of an integrated metabolomics approach in nutrition research was highlighted...
  69. ncbi Personalizing foods: is genotype necessary?
    Laurent B Fay
    Nestle Research Centre, PO Box 44, Vers chez les Blanc, CH 1000, Lausanne 26, Switzerland
    Curr Opin Biotechnol 19:121-8. 2008
    ....
  70. ncbi Do trans fatty acids from industrially produced sources and from natural sources have the same effect on cardiovascular disease risk factors in healthy subjects? Results of the trans Fatty Acids Collaboration (TRANSFACT) study
    Jean Michel Chardigny
    Institut National de Recherche Agronomique and Food Science, UMR1019, Clermont Ferrand, France
    Am J Clin Nutr 87:558-66. 2008
    ..Putative differences between the effects of TFAs from industrially produced and natural sources on CVD risk markers were not previously investigated in healthy subjects...
  71. ncbi Applications of metabolomics in agriculture
    Richard A Dixon
    Plant Biology Division, Samuel Roberts Noble Foundation, 2510 Sam Noble Parkway, Ardmore, OK 73401, USA
    J Agric Food Chem 54:8984-94. 2006
    ..Selected presentations from an American Chemical Society symposium held in March 2005 have been assembled to highlight the emerging application of metabolomics in agriculture...
  72. ncbi Individual variation in the metabolic syndrome: a new perspective on the debate
    Angela M Zivkovic
    Am J Clin Nutr 85:240-1; author reply 241-2. 2007