Keith Georgeson

Summary

Affiliation: University of Alabama at Birmingham
Country: USA

Publications

  1. ncbi request reprint Laparoscopic-assisted anorectal pull-through
    Keith Georgeson
    Department of Pediatric Surgery, Children s Hospital of Alabama, Birmingham, AL 35233, USA
    Semin Pediatr Surg 16:266-9. 2007
  2. ncbi request reprint Laparoscopic-assisted approaches for the definitive surgery for Hirschsprung's disease
    Keith E Georgeson
    Division of Pediatric Surgery, University of Alabama at Birmingham, Birmingham, AL, USA
    Semin Pediatr Surg 13:256-62. 2004
  3. ncbi request reprint Molecular basis of melanocortin-4 receptor for AGRP inverse agonism
    Min Chen
    Department of Surgery, University of Alabama at Birmingham, 35205, USA
    Regul Pept 136:40-9. 2006
  4. ncbi request reprint Molecular characterization of human melanocortin-3 receptor ligand-receptor interaction
    Min Chen
    Department of Surgery, University of Alabama at Birmingham, Birmingham, Alabama 35233, USA
    Biochemistry 45:1128-37. 2006
  5. ncbi request reprint Ectopic brain tissue in a neonate
    R Shane Tubbs
    Department of Cell Biology, University of Alabama at Birmingham, Birmingham, Ala, USA
    Pediatr Neurosurg 39:136-8. 2003
  6. doi request reprint Appendectomy using single-incision pediatric endosurgery for acute and perforated appendicitis
    Oliver J Muensterer
    Division of Pediatric Surgery, Department of Surgery, Children s Hospital of Alabama, University of Alabama at Birmingham, 1600 7th Avenue South, ACC 300, Birmingham, AL 35233, USA
    Surg Endosc 24:3201-4. 2010
  7. ncbi request reprint Molecular mechanism of the intracellular segments of the melanocortin-4 receptor for NDP-MSH signaling
    Yingkui Yang
    Department of Surgery, University of Alabama at Birmingham, Birmingham, Alabama 35205, USA
    Biochemistry 44:6971-9. 2005
  8. doi request reprint Single-incision laparoscopic pyloromyotomy: initial experience
    Oliver J Muensterer
    Department of Pediatric Surgery, Children s Hospital of Alabama, University of Alabama at Birmingham, 1600 7th Avenue South ACC 300, Birmingham, AL 35233, USA
    Surg Endosc 24:1589-93. 2010
  9. pmc Contribution of the conserved amino acids of the melanocortin-4 receptor in [corrected] [Nle4,D-Phe7]-alpha-melanocyte-stimulating [corrected] hormone binding and signaling
    Min Chen
    Department of Surgery and Nutrition, University of Alabama, Birmingham, AL 35205, USA
    J Biol Chem 282:21712-9. 2007
  10. ncbi request reprint Molecular determination of agouti-related protein binding to human melanocortin-4 receptor
    Yingkui Yang
    Division of Pediatric Surgery, University of Alabama at Birmingham, 300 ACC, 1600 7th Avenue South, Birmingham, AL 35233, USA
    Mol Pharmacol 64:94-103. 2003

Collaborators

  • Y K Yang
  • Min Chen
  • O J Muensterer
  • Ira Gantz
  • Namasivayam Ambalavanan
  • R Shane Tubbs
  • Victor Hruby
  • Ramanath N Haricharan
  • Douglas C Barnhart
  • Charles J Aprahamian
  • Carroll M Harmon
  • Traci L Morgan
  • Ahmet Celik
  • David J Askenazi
  • Ahmed Marwan
  • Jacqueline M Saito
  • Gary Cutter
  • Kiya Hamilton
  • Debbie Laney
  • Richard Kaslow
  • Reed A Dimmitt
  • Carrol M Harmon
  • Geni F Smith
  • Lee M Hilliard
  • Jeong Meen Seo
  • Jared M Roberts
  • Elizabeth C Mroczek-Musulman
  • William D Hardin
  • David R Kelly
  • Tara J Loux

Detail Information

Publications26

  1. ncbi request reprint Laparoscopic-assisted anorectal pull-through
    Keith Georgeson
    Department of Pediatric Surgery, Children s Hospital of Alabama, Birmingham, AL 35233, USA
    Semin Pediatr Surg 16:266-9. 2007
    ..Some physiologic measurements after LAARP indicate that outcomes are at least equivalent to PSARP. Long-term outcomes have not been reported after LAARP...
  2. ncbi request reprint Laparoscopic-assisted approaches for the definitive surgery for Hirschsprung's disease
    Keith E Georgeson
    Division of Pediatric Surgery, University of Alabama at Birmingham, Birmingham, AL, USA
    Semin Pediatr Surg 13:256-62. 2004
    ..Total colon aganglionosis or aganglionosis of the ascending colon is managed by a laparoscopic-assisted Duhamel procedure which provides a better reservoir in patients with a short or absent colon...
  3. ncbi request reprint Molecular basis of melanocortin-4 receptor for AGRP inverse agonism
    Min Chen
    Department of Surgery, University of Alabama at Birmingham, 35205, USA
    Regul Pept 136:40-9. 2006
    ..Our results also indicate that the residues D90 in TM2 and D298 in TM7 of hMC4R are involved in not only NDP-MSH mediated receptor activation but also AGRP mediated inverse agonism...
  4. ncbi request reprint Molecular characterization of human melanocortin-3 receptor ligand-receptor interaction
    Min Chen
    Department of Surgery, University of Alabama at Birmingham, Birmingham, Alabama 35233, USA
    Biochemistry 45:1128-37. 2006
    ..Importantly, L165 in TM3 is critical for agonist or antagonist selectivity. These results provide important information about the molecular determinants of hMC3R responsible for ligand binding and receptor signaling...
  5. ncbi request reprint Ectopic brain tissue in a neonate
    R Shane Tubbs
    Department of Cell Biology, University of Alabama at Birmingham, Birmingham, Ala, USA
    Pediatr Neurosurg 39:136-8. 2003
    ..This case represents the rare ectopic 'brain'. We review this case as well as the literature concerning these unusual masses...
  6. doi request reprint Appendectomy using single-incision pediatric endosurgery for acute and perforated appendicitis
    Oliver J Muensterer
    Division of Pediatric Surgery, Department of Surgery, Children s Hospital of Alabama, University of Alabama at Birmingham, 1600 7th Avenue South, ACC 300, Birmingham, AL 35233, USA
    Surg Endosc 24:3201-4. 2010
    ....
  7. ncbi request reprint Molecular mechanism of the intracellular segments of the melanocortin-4 receptor for NDP-MSH signaling
    Yingkui Yang
    Department of Surgery, University of Alabama at Birmingham, Birmingham, Alabama 35205, USA
    Biochemistry 44:6971-9. 2005
    ....
  8. doi request reprint Single-incision laparoscopic pyloromyotomy: initial experience
    Oliver J Muensterer
    Department of Pediatric Surgery, Children s Hospital of Alabama, University of Alabama at Birmingham, 1600 7th Avenue South ACC 300, Birmingham, AL 35233, USA
    Surg Endosc 24:1589-93. 2010
    ..Laparoscopic pyloromyotomy has become the standard treatment for hypertrophic pyloric stenosis. Single-incision laparoscopic surgery is an emerging operative approach that utilizes the umbilical scar to hide the surgical incision...
  9. pmc Contribution of the conserved amino acids of the melanocortin-4 receptor in [corrected] [Nle4,D-Phe7]-alpha-melanocyte-stimulating [corrected] hormone binding and signaling
    Min Chen
    Department of Surgery and Nutrition, University of Alabama, Birmingham, AL 35205, USA
    J Biol Chem 282:21712-9. 2007
    ..In conclusion, our results suggest that the conserved residues in the TM2, TM3, and TM6 of the hMC4R are responsible for alpha-MSH binding and signaling...
  10. ncbi request reprint Molecular determination of agouti-related protein binding to human melanocortin-4 receptor
    Yingkui Yang
    Division of Pediatric Surgery, University of Alabama at Birmingham, 300 ACC, 1600 7th Avenue South, Birmingham, AL 35233, USA
    Mol Pharmacol 64:94-103. 2003
    ..The second and third extracellular loops of MC4R are important for AGRP 87-132 N-terminal binding, whereas the third and fourth transmembrane domains of hMC4R are crucial for AGRP 110-117 binding...
  11. doi request reprint Splenectomy reduces packed red cell transfusion requirement in children with sickle cell disease
    Ramanath N Haricharan
    Division of Pediatric Surgery, University of Alabama at Birmingham, Birmingham, AL 35233, USA
    J Pediatr Surg 43:1052-6. 2008
    ..The purpose of the study was to measure the effect of splenectomy on packed-cell transfusion requirement in children with sickle cell disease...
  12. ncbi request reprint Molecular determinants of human melanocortin-4 receptor responsible for antagonist SHU9119 selective activity
    Yingkui Yang
    Department of Surgery, University of Alabama at Birmingham, Alabama 35233, USA
    J Biol Chem 277:20328-35. 2002
    ..This report provides the details of the molecular recognition of SHU9119 antagonism at hMC4R and shows that amino acid Leu(133) of hMC4R plays a key role in melanocortin receptor subtype specificity...
  13. doi request reprint Laparoscopic pyloromyotomy: effect of resident training on complications
    Ramanath N Haricharan
    Division of Pediatric Surgery, University of Alabama at Birmingham, Birmingham, AL 35233, USA
    J Pediatr Surg 43:97-101. 2008
    ..The purpose of this study was to characterize the safety of laparoscopic pyloromyotomy and examine the effect of resident training on the occurrence of complications...
  14. ncbi request reprint Laparoscopic-assisted pull-through for Hirschsprung's disease
    Keith E Georgeson
    Department of Surgery, Children s Hospital of Alabama, Birmingham, USA
    Semin Pediatr Surg 11:205-10. 2002
    ..Advantages of this approach include reduced discomfort, the early initiation of defecation through a normally positioned ganglionic colon and rectum, and reduced postoperative hospitalization...
  15. doi request reprint Acute kidney injury and renal replacement therapy independently predict mortality in neonatal and pediatric noncardiac patients on extracorporeal membrane oxygenation
    David J Askenazi
    Department of Pediatrics, University of Alabama at Birmingham, School of Public Health, Birmingham, AL, USA
    Pediatr Crit Care Med 12:e1-6. 2011
    ..AKI and RRT portend poor outcomes independent of comorbidities and illness severity in several critically ill populations...
  16. ncbi request reprint Minimally invasive surgery in neonates
    Keith Georgeson
    Department of Surgery, University of Alabama, 300 Ambulatory Care Center, 1600 7th Avenue South, Birmingham, AL 35233, USA
    Semin Neonatol 8:243-8. 2003
    ..MIS is now being performed in both the neonatal chest and abdomen. This article reviews these new developments and discusses the potential for even further improvements in neonatal surgery in the future...
  17. ncbi request reprint Functional characterization of the modified melanocortin peptides responsible for ligand selectivity at the human melanocortin receptors
    Min Chen
    Department of Surgery, University of Alabama at Birmingham, Birmingham, AL 35233, USA
    Peptides 27:2836-45. 2006
    ..These findings indicate that DPhe in tetrapeptide plays an important role in ligand selectivity and specific residue TM3 of the melanocortin receptors is crucial for ligand selectivity...
  18. ncbi request reprint Minimally invasive surgery in the neonate: review of current evidence
    Keith E Georgeson
    Division of Pediatric Surgery, Children s Hospital of Alabama, University of Alabama, Birmingham, AL, USA
    Semin Perinatol 28:212-20. 2004
    ..This article summarizes the status of these techniques in neonates...
  19. doi request reprint Older age at diagnosis of Hirschsprung disease decreases risk of postoperative enterocolitis, but resection of additional ganglionated bowel does not
    Ramanath N Haricharan
    Division of Pediatric Surgery, University of Alabama at Birmingham, Birmingham, AL 35233, USA
    J Pediatr Surg 43:1115-23. 2008
    ..This study was conducted to determine the effect of age at diagnosis and length of ganglionated bowel resected on postoperative Hirschsprung-associated enterocolitis (HAEC)...
  20. doi request reprint Hirschsprung disease
    Ramanath N Haricharan
    Division of Pediatric Surgery, Department of General Surgery, University of Alabama at Birmingham, Birmingham, Alabama 35233, USA
    Semin Pediatr Surg 17:266-75. 2008
    ..In neonates, the advancement of treatment strategies for Hirschsprung disease continues with reduced patient morbidity and improved outcomes...
  21. ncbi request reprint Results of laparoscopic antireflux procedures in neurologically normal infants and children
    Keith Georgeson
    University of Birmingham, Birmingham, AL, USA
    Semin Laparosc Surg 9:172-6. 2002
    ..The fundoplication should be loose and no longer than 2 cm in length. Long-term follow-up has shown recurrence to be low in children who are neurologically normal as long as they do not gag and retch recurrently...
  22. doi request reprint Use of laparoscopy in the management of pediatric abdominal trauma
    Ahmed Marwan
    Division of Pediatric Surgery, Children s Hospital of Alabama and the University of Alabama at Birmingham, Birmingham, Alabama, USA
    J Trauma 69:761-4. 2010
    ..We performed a systematic analysis of our experience concerning indications, procedures, and outcomes using laparoscopy in pediatric abdominal trauma patients...
  23. ncbi request reprint Laparoscopic-assisted total colectomy with pouch reconstruction
    Keith E Georgeson
    Department of Surgery, Children s Hospital of Alabama, Birmingham, USA
    Semin Pediatr Surg 11:233-6. 2002
    ..An early experience with this technique at the Children's Hospital in Alabama is described for children with ulcerative colitis...
  24. doi request reprint Smaller scars--what is the big deal: a survey of the perceived value of laparoscopic pyloromyotomy
    Ramanath N Haricharan
    Division of Pediatric Surgery, University of Alabama at Birmingham, Birmingham, AL 35233, USA
    J Pediatr Surg 43:92-6; discussion 96. 2008
    ..Laparoscopic and open pyloromyotomies are equally safe and effective, with the principal benefit of laparoscopy being better cosmesis. The goal of this study was to measure the perceived value of laparoscopic pyloromyotomy...
  25. ncbi request reprint U-stitch laparoscopic gastrostomy technique has a low rate of complications and allows primary button placement: experience with 461 pediatric procedures
    Charles J Aprahamian
    Division of Pediatric Surgery, University of Alabama Birmingham, Birmingham, Alabama, USA
    J Laparoendosc Adv Surg Tech A 16:643-9. 2006
    ..The purpose of this study was to quantify the completion rate and the occurrence of complications in a large single-institution experience...
  26. ncbi request reprint Revision Nissen fundoplication can be completed laparoscopically with a low rate of complications: a single-institution experience with 72 children
    Ahmet Celik
    Division of Pediatric Surgery, University of Alabama at Birmingham, Birmingham, AL 35233, USA
    J Pediatr Surg 41:2081-5. 2006
    ..Recurrent gastroesophageal reflux is a common complication after fundoplication and is often treated with revision fundoplication. We report our experience with laparoscopic redo fundoplication...