Jonathan R Genzen

Summary

Affiliation: University of Utah
Country: USA

Publications

  1. Needham L, Smy L, Lee M, Kunzler T, Genzen J. Phlebotomy tube interference with nuclear magnetic resonance (NMR) lipoprotein subclass analysis. Clin Chim Acta. 2019;488:235-241 pubmed publisher
    ..NMR lipoprotein subclass analysis should be standardized by both tube type and tube size to prevent risk of analytical interference. ..
  2. Genzen J, La ulu S, Wyness S, Scholes K, Signorelli H, Greer R. Identifying and Eliminating Laboratory Contamination by Topical Testosterone Therapeutics. Clin Chem. 2019;65:67-73 pubmed publisher
    ..Laboratory policies and procedures were also revised to minimize future risk. ..
  3. Owen W, Caron J, Genzen J. Liver function testing on the Abaxis Piccolo Xpress: Use in Ebola virus disease protocols. Clin Chim Acta. 2015;446:119-27 pubmed publisher
  4. Scholes K, La ulu S, Ence A, Logan H, Parker R, Strathmann F, et al. Evaluation of test strips for the rapid identification of ethylenediaminetetraacetic acid (EDTA) specimens. Lab Med. 2015;46:97-108 pubmed publisher
    ..Indeterminate reactions required further investigation. Dip mode can produce analytical problems for assays that measure (or are interfered by) the contents of test strips. ..
  5. Owen W, Thatcher M, Crabtree K, Greer R, Strathmann F, Straseski J, et al. Body fluid matrix evaluation on a Roche cobas 8000 system. Clin Biochem. 2015;48:911-4 pubmed publisher
    ..Such findings support the utility of ongoing body fluid validation initiatives conducted to maintain compliance with regulatory requirements. ..
  6. Owen W, Hunsaker J, Genzen J. Alpha-fetoprotein in pericardial, peritoneal, and pleural fluids: A body fluid matrix evaluation. Clin Biochem. 2018;56:109-112 pubmed publisher
    ..6%. Imprecision was ?6.0% CV for all three body fluids at both high and low AFP concentrations. Matrix interference with AFP testing was not observed for pericardial, peritoneal, or pleural fluids on the Beckman UniCel DxI 800 system. ..
  7. Genzen J, Hunsaker J, Nelson L, Faine B, Krasowski M. N-acetylcysteine interference of Trinder-based assays. Clin Biochem. 2016;49:100-4 pubmed publisher
    ..Evidence for relatively minor inhibition of Cr was observed in patients after NAC administration. NAC inhibition of the assays investigated typically occurs at concentrations higher than expected during IV and oral NAC therapy. ..
  8. Hunsaker J, La ulu S, Wyness S, Genzen J. Lipemic interference of ceruloplasmin assays - An evaluation of lipid removal methods. Clin Chim Acta. 2018;480:71-78 pubmed publisher
    ..CERU assays on different platforms have varying susceptibility to lipemic interference. L-index thresholds derived using Intralipid may not accurately represent interference caused by endogenous lipemia. ..
  9. Genzen J, Gosselin J, Wilson T, Racila E, Krasowski M. Analysis of vitamin D status at two academic medical centers and a national reference laboratory: result patterns vary by age, gender, season, and patient location. BMC Endocr Disord. 2013;13:52 pubmed publisher
    ..Severe vitamin D deficiency is much more common than vitamin D toxicity. ..

More Information

Publications11

  1. Genzen J, Mohlman J, Lynch J, Squires M, Weiss R. Laboratory-Developed Tests: A Legislative and Regulatory Review. Clin Chem. 2017;63:1575-1584 pubmed publisher
    ..Future regulatory and/or legislative efforts may be required to resolve this uncertainty. ..
  2. Lin D, Genzen J. Concordance analysis of paired cancer antigen (CA) 15-3 and 27.29 testing. Breast Cancer Res Treat. 2018;167:269-276 pubmed publisher
    ..While generally concordant, CA 15-3 and CA 27.29 results should not be used interchangeably. The present report provides no evidence for added value in performing both tests routinely for individual patients. ..