Research Topics
| Larry M GentilelloSummaryAffiliation: University of Texas Southwestern Medical Center Country: USA Publications
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Detail Information
Publications
Low-dose ethanol alters the cardiovascular, metabolic, and respiratory compensation for severe blood lossKathleen H McDonough
Department of Physiology, Louisiana State University Health Sciences Center, New Orleans 70112, USA
J Trauma 53:541-8; discussion 548. 2002..In survivors of shock and resuscitation, compensation is compromised and physiologic reserve is adversely affected by acute EtOH intake...
Effect of alcohol on Glasgow Coma Scale in head-injured patientsLance Stuke
Department of Surgery, Division of Burns, Trauma and Surgical Critical Care, University of Texas Southwestern Medical School, Dallas, TX 75390 9158, USA
Ann Surg 245:651-5. 2007..The purpose of this study was to test the hypothesis that the presence of blood alcohol has a clinically significant impact on GCS in TBI patients...- Alcohol interventions in trauma centers: the opportunity and the challengeLarry M Gentilello
Department of Surgery, University of Texas Southwestern Medical School, Dallas, TX 75390-9158, USA
J Trauma 59:S18-20. 2005 - Alcohol screening and intervention in trauma centers: confidentiality concerns and legal considerationsLarry M Gentilello
Department of Surgery, University of Texas Southwestern Medical School, Dallas, Texas 75390-9158, USA
J Trauma 59:1250-4; discussion 1254-5. 2005 - Confronting the obstacles to screening and interventions for alcohol problems in trauma centersLarry M Gentilello
Division of Burns, Trauma, and Critical Care, University of Texas Southwestern Medical School, Dallas, TX 75390 9158, USA
J Trauma 59:S137-43; discussion S146-66. 2005.... - Alcohol interventions for trauma patients treated in emergency departments and hospitals: a cost benefit analysisLarry M Gentilello
Department of Surgery, Division of Burns, Trauma and Critical Care, Parkland Memorial Hospital, University of Texas Southwestern Medical School, 5323 Harry Hines Boulevard, MC 9158, Dallas, Texas, USA
Ann Surg 241:541-50. 2005..To determine if brief alcohol interventions in trauma centers reduce health care costs... - Alcohol and injury: American College of Surgeons Committee on trauma requirements for trauma center interventionLarry M Gentilello
University of Texas Southwestern Medical Center, Dallas, TX, USA
J Trauma 62:S44-5. 2007 - Chronic consequences of acute injuries: worse survival after dischargeShahid Shafi
Institute for Health Care Research and Improvement, Baylor Health Care System, Dallas, Texas 76051, USA
J Trauma Acute Care Surg 73:699-703. 2012..We hypothesized that survival rates in trauma patients who survive to discharge remain stable afterward... 
Quality of Care Within a Trauma Center Is not Altered by Injury TypeShahid Shafi
Department of Surgery, Division of Burns, Trauma and Surgical Critical Care, University of Texas Southwestern Medical School, Dallas, Texas, USA
J Trauma 68:716-20. 2010..Previous studies have demonstrated variations in severity-adjusted mortality between trauma centers. However, it is not clear if outcomes vary by the type of injury being treated...- The implications of alcohol intoxication and the Uniform Policy Provision Law on trauma centers; a national trauma data bank analysis of minimally injured patientsTerence O'Keeffe
Division of Trauma, Critical Care, and Emergency Surgery, Department of Surgery, University of Arizona, Tucson, Arizona 85724, USA
J Trauma 66:495-8. 2009..We hypothesized that patients injured while under the influence of alcohol require more diagnostic tests, procedures, and hospital admissions, leading to higher hospital charges... - Is there a role for aggressive use of fresh frozen plasma in massive transfusion of civilian trauma patients?Frederick A Moore
Department of Surgery, The Methodist Hospital, Houston, TX, USA
Am J Surg 196:948-58; discussion 958-60. 2008..Damage control resuscitation (DCR) with early plasma in combat casualties requiring massive transfusion (MT) decreases early deaths from bleeding... - Moving beyond personnel and process: a case for incorporating outcome measures in the trauma center designation processShahid Shafi
Division of Burn, Trauma, and Surgical Critical Care, Department of Surgery, University of Texas Southwestern Medical Center, Dallas, TX 75390 9158, USA
Arch Surg 143:115-9; discussion 120. 2008..Similarly designated trauma centers do not achieve similar outcomes... - Moving from "optimal resources" to "optimal care" at trauma centersShahid Shafi
Institute for Health Care Research and Improvement, Baylor Health Care System, Dallas, Texas, USA
J Trauma Acute Care Surg 72:870-7. 2012..We hypothesized that improved compliance with trauma-specific clinical processes of care (POC) is associated with reduced in-hospital mortality... - Ethnic disparities exist in trauma careShahid Shafi
Department of Surgery, University of Texas Southwestern Medical Center, Dallas, Texas, USA
J Trauma 63:1138-42. 2007..Ethnic disparities in access to health care have been documented in other diseases, but have not been studied in trauma care. We hypothesized that access to rehabilitation after TBI is influenced by race or ethnicity... - Hemoglobin drops within minutes of injuries and predicts need for an intervention to stop hemorrhageBrandon Bruns
Division of Burns, Trauma and Critical Care, Department of Surgery, University of Texas Southwestern Medical School, Dallas, TX, USA
J Trauma 63:312-5. 2007..We hypothesized that Hgb levels measured within minutes of arrival can identify trauma patients who are actively bleeding... - Increased risk of death associated with hypotension is not altered by the presence of brain injury in pediatric trauma patientsMark A Gunst
Division of Burns, Trauma and Surgical Critical Care, Department of Surgery, University of Texas Southwestern Medical School, 5323 Harry Hines Blvd, Dallas, TX 75390 9158, USA
Am J Surg 194:741-4; discussion 744-5. 2007..We hypothesized that systemic hypotension increases mortality in pediatric patients with TBI more than it does in pediatric patients with extracranial injuries only... - Massive transfusion in trauma patients: tissue hemoglobin oxygen saturation predicts poor outcomeFrederick A Moore
Department of Surgery, The Methodist Hospital, Houston Texas, USA
J Trauma 64:1010-23. 2008.... - Could Beta blockade improve outcome after injury by modulating inflammatory profiles?Randall S Friese
Division of Burn, Trauma, Critical Care, Department of Surgery, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas, USA
J Trauma 64:1061-8. 2008..In vitro evidence supports that BB modulates the postinjury inflammatory response. The purpose of this study was to examine the effects of BB on inflammatory profiles in injured patients at increased risk for heart disease... - Centers for Medicare and Medicaid services quality indicators do not correlate with risk-adjusted mortality at trauma centersShahid Shafi
Department of Surgery, University of Texas Southwestern Medical School, Dallas, Texas, USA
J Trauma 68:771-7. 2010..We hypothesized that compliance with CMS quality indicators would correlate with risk-adjusted mortality rates in trauma patients... - Health care reform at trauma centers--mortality, complications, and length of stayShahid Shafi
Institute for Health Care Research and Improvement, Baylor Health Care System, Dallas, Texas 76051, USA
J Trauma 69:1367-71. 2010..We hypothesized that LOS is not primarily determined by unmodifiable factors, such as age and injury severity, but is primarily dependent on the development of potentially preventable complications... - More operations, more deaths? Relationship between operative intervention rates and risk-adjusted mortality at trauma centersShahid Shafi
Institute for Health Care Research and Improvement, Baylor Health Care System, Dallas, Texas 76051, USA
J Trauma 69:70-7. 2010..We hypothesized that centers with good outcomes undertake critical operative interventions aggressively, thereby avoiding complications and deaths... - Predictors of early versus late timing of pulmonary embolus after traumatic injuryScott C Brakenridge
Department of Surgery, University of Texas Southwestern Medical Center, Dallas, USA
Am J Surg 201:209-15. 2011..To identify risk factors predictive of pulmonary embolus (PE) timing after a traumatic injury... - Ethnic disparities in initial management of trauma patients in a nationwide sample of emergency department visitsShahid Shafi
Division of Burns, Trauma, and Critical Care, Department of Surgery, University of Texas Southwestern Medical School, 5323 Harry Hines Blvd, Mail Stop 9158, Dallas, TX 75390 9158, USA
Arch Surg 143:1057-61; discussion 1061. 2008..We hypothesized that initial assessment of injured patients in EDs is affected by patient ethnicity... - Ethnic disparities in long-term functional outcomes after traumatic brain injuryKristan L Staudenmayer
Department of Surgery, University of California, San Francisco, California, USA
J Trauma 63:1364-9. 2007..The current study was undertaken to determine whether there are specific types of functional deficits that disproportionately affect ethnic minorities after TBI... - Trauma quality improvement using risk-adjusted outcomesShahid Shafi
Department of Surgery, Division of Burns, Trauma and Surgical Critical Care, University of Texas Southwestern Medical School, Dallas, Texas, USA
J Trauma 64:599-604; discussion 604-6. 2008..We hypothesized that significant variations in outcomes exist across similar level ACS-verified trauma centers despite availability of similar resources... - Financial triage in transfer of trauma patients: a myth or a reality?Jennifer Parks
Department of Surgery, Division of Burns, Trauma and Surgical Critical Care, University of Texas Southwestern Medical School, Dallas, TX 75390 9158, USA
Am J Surg 198:e35-8. 2009..It has been alleged that smaller hospitals transfer out uninsured trauma patients (wallet biopsy), putting the financial burden on major trauma centers... - Inequity of rehabilitation services after traumatic injuryRam Nirula
Department of Surgery, Division of General Surgery, University of Utah School of Medicine, Salt Lake City, Utah 84132, USA
J Trauma 66:255-9. 2009..We hypothesized that a lack of insurance is associated with a reduced likelihood of being transferred to a rehabilitation facility after trauma... - Barriers to compliance with evidence-based care in traumaNadine Rayan
Institute for Health Care Research and Improvement, Baylor Health Care System, Dallas, Texas 76051, USA
J Trauma Acute Care Surg 72:585-92; discussion 592-3. 2012..We have preciously demonstrated that trauma patients receive less than two-thirds of the care recommended by evidence-based medicine. The purpose of this study was to identify patients least likely to receive optimal care... - Effects of early use of external pelvic compression on transfusion requirements and mortality in pelvic fracturesVafa Ghaemmaghami
Department of Surgery, Division of Burn, Trauma and Critical Care, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Mail Stop 9158, Dallas, TX 75390 9158, USA
Am J Surg 194:720-3; discussion 723. 2007..We hypothesized that early use of external mechanical compression (EMC) reduces hemorrhage and mortality associated with pelvic fractures... - Racial disparities in long-term functional outcome after traumatic brain injuryShahid Shafi
Department of Surgery, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9158, USA
J Trauma 63:1263-8; discussion 1268-70. 2007..We hypothesized that access to acute rehabilitation and long-term functional outcomes among traumatic brain injury (TBI) patients are influenced by patient race and ethnicity... - Transfusions and long-term functional outcomes in traumatic brain injuryMatthew A Warner
Department of Neurology, University of Texas Southwestern Medical Center, Parkland Memorial Hospital, Dallas, Texas, USA
J Neurosurg 113:539-46. 2010..While evidence suggests that transfusions are associated with poor hospital outcomes, no study has examined transfusions and long-term functional outcomes in this population. The preferred transfusion threshold remains controversial... - Quantity and quality of sleep in the surgical intensive care unit: are our patients sleeping?Randall S Friese
Division of Burn, Trauma, Critical Care, Department of Surgery, University of Texas Southwestern Medical Center at Dallas, Texas, USA
J Trauma 63:1210-4. 2007..The purpose of this study was to describe the quantity and quality of sleep as well as sleep architecture, as defined by polysomnography (PSG), in patients cared for in the surgical ICU... - Significant variations in mortality occur at similarly designated trauma centersShahid Shafi
Department of Surgery, Division of Burns, Trauma, and Surgical Critical Care, University of Texas Southwestern Medical School, Dallas, TX 75390 9158, USA
Arch Surg 144:64-8. 2009..Mortality rates vary across designated trauma centers (TC), even after controlling for injury severity... - Long-term fetal outcomes in pregnant trauma patientsJason L Sperry
Department of Surgery, Division of Burns, Trauma and Surgical Critical Care, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Mail Stop 9158, Dallas, TX 75390-9158, USA
Am J Surg 192:715-21. 2006..A history of trauma during gestation is a risk factor for poor pregnancy outcome... - Effect of the Uniform Accident and Sickness Policy Provision Law on alcohol screening and intervention in trauma centersLarry M Gentilello
Department of Surgery, The University of Texas Southwestern Medical School, Dallas, Texas 75390 9158, USA
J Trauma 59:624-31. 2005.... - Trauma operative skills in the era of nonoperative management: the trauma exposure course (TEC)Mark Gunst
Department of Surgery, Division of Burns, Trauma, and Critical Care, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9158, USA
J Trauma 67:1091-6. 2009..We hypothesized that a structured skills curriculum using fresh cadavers would improve participants' self-confidence in surgical exposure of human anatomic structures for trauma... - Waiting for the patient to "sober up": Effect of alcohol intoxication on glasgow coma scale score of brain injured patientsJason L Sperry
Division of Burns, Trauma and Surgical Critical Care, Department of Surgery, University of Texas Southwestern Medical School, Dallas, Texas 75390-9158, USA
J Trauma 61:1305-11. 2006..Hence, alterations in GCS score after TBI should not be attributed to alcohol intoxication, as doing so might result in inappropriate delays in monitoring and therapeutic interventions... - Serum B-type natriuretic peptide: a marker of fluid resuscitation after injury?Randall S Friese
Division of Burn, Trauma, Critical Care, Department of Surgery, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390 9158, USA
J Trauma 62:1346-50; discussion 1350-1. 2007..However, the use of BNP as a marker of fluid overload during resuscitation from injury has not been previously described... - The use of leukoreduced red blood cell products is associated with fewer infectious complications in trauma patientsRandall S Friese
Division of Burn, Trauma, Critical Care, Department of Surgery, University of Texas Southwestern Medical Center at Dallas, Dallas, TX, USA
Am J Surg 196:56-61. 2008..The purpose of this study was to determine the effect of prestorage leukoreduction on infectious complications in injured patients... - Protection against head injuries should not be optional: a case for mandatory installation of side-curtain air bagsLance E Stuke
University of Texas Southwestern Medical School, Dallas, TX, USA
Am J Surg 200:496-9. 2010..More than 9,000 vehicle occupants die each year in side-impact vehicle collisions, primarily from head injuries. The authors hypothesized that side-curtain air bags significantly improve head and neck safety in side-impact crash testing... - Spatial analysis of injury-related deaths in Dallas County using a geographic information systemAdil Abdalla
Department of Surgery Abdalla, Gunst, Ghaemmaghami, Barber, Gentilello, Shafi and the Department of Pathology Gruszecki, Urban, The University of Texas Southwestern Medical School, Dallas, TX and the Institute for Health Care Research and Improvement, Baylor Health Care System, Dallas, TX Shafi
Proc (Bayl Univ Med Cent) 25:208-13. 2012..GIS mapping was able to depict high-risk geographic "hot spots" for IRDs. In conclusion, GIS spatial analysis identified geographic clusters of IRDs, which were restricted to only one of 26 cities in the county... - Postinjury employment as a surrogate for functional outcomes: a quality indicator for trauma systemsJennifer K Parks
Department of Surgery, Division of Burns, Trauma, Surgical Critical Care Parks, Gentilello and the Department of Neurology Diaz Arrastia, The University of Texas Southwestern Medical Center, Dallas, Texas and the Institute for Health Care Research and Improvement, Baylor Health Care System, Dallas, Texas Shafi
Proc (Bayl Univ Med Cent) 23:355-8. 2010..Once validated in other studies, postinjury employment may be used as an indicator to monitor functional outcomes in trauma registries... - Systemic hypotension is a late marker of shock after trauma: a validation study of Advanced Trauma Life Support principles in a large national sampleJennifer K Parks
Department of Surgery, Division of Burns, Trauma, Surgical Critical Care, 5323 Harry Hines Blvd, Dallas, TX 75390-9158, USA
Am J Surg 192:727-31. 2006..CONCLUSIONS: We validated the Advanced Trauma Life Support principle that systemic hypotension is a late marker of shock. A normal blood pressure should not deter aggressive evaluation and resuscitation of trauma patients... - Abdominal ultrasound is an unreliable modality for the detection of hemoperitoneum in patients with pelvic fractureRandall S Friese
Division of Burn, Trauma, Critical Care, Department of Surgery, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390 9158, USA
J Trauma 63:97-102. 2007..The purpose of this study was to determine the sensitivity and specificity of FAST for the detection of hemoperitoneum in patients with pelvic fracture and an increased risk for hemorrhage... - Pulmonary artery catheter use is associated with reduced mortality in severely injured patients: a National Trauma Data Bank analysis of 53,312 patientsRandall S Friese
Parkland Memorial Hospital, Division of Burn, Trauma, Critical Care, Department of Surgery, University of Texas Southwestern Medical Center at Dallas, TX, USA
Crit Care Med 34:1597-601. 2006..This is the first study to demonstrate a benefit of PAC use in trauma patients... - The liver bag: report of a new technique for treating severe, exsanguinating hepatic injuriesScott Sattler
Department of Surgery, Harborview Medical Center, University of Washington, Seattle, Washington, USA
J Trauma 57:884-6. 2004 - Increased fatalities after motorcycle helmet law repeal: is it all because of lack of helmets?Terence O'Keeffe
Division of Burn, Trauma and Critical Care, Department of Surgery, University of Texas Southwestern Medical School, Dallas, Texas 75390 9158, USA
J Trauma 63:1006-9. 2007..We examined the effect of the repeal of Florida's helmet law in July 2000 to test the hypothesis that the increase in fatalities observed after repeal resulted from an increase in the number of motorcycle riders... - Laparoscopy is sufficient to exclude occult diaphragm injury after penetrating abdominal traumaRandall S Friese
Department of Surgery, Division of Burn, Trauma, Critical Care, University of Texas Southwestern Medical Center, Dallas, Texas, USA
J Trauma 58:789-92. 2005..We hypothesized that laparoscopy alone is sufficient to exclude diaphragm injury after penetrating thoracoabdominal trauma... - Heart rate: is it truly a vital sign?Karen J Brasel
Department of Surgery, Medical College of Wisconsin, Wisconsin 53226, USA
J Trauma 62:812-7. 2007..We sought to determine whether admission heart rate is a valid predictor of hemodynamically significant injuries... - The risk of reinjury in relation to time since first injury: a retrospective population-based studyStewart S Worrell
Departmens of Epidemiology, Surgery, University of Washington, Seattle, Washington 98104-2499, USA
J Trauma 60:379-84. 2006..Periodic interventions through 5 years after injury, particularly in certain high-risk groups, might have lasting effects on reinjury rates... - The effect of computerized tailored brief advice on at-risk drinking in subcritically injured trauma patientsTim Neumann
Department of Anaesthesiology and Intensive Care Medicine, , , Germany
J Trauma 61:805-14. 2006..Research is needed to further evaluate and adapt information technology to provide preventive clinical services in the ED... - Nationwide survey of alcohol screening and brief intervention practices at US Level I trauma centersFrancine Terrell
Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, WA 98104, USA
J Am Coll Surg 207:630-8. 2008.... - Alcohol and the intensive care unit: it's not just an antisepticLarry M Gentilello
Crit Care Med 35:627-8. 2007 - Usefulness of the abbreviated injury score and the injury severity score in comparison to the Glasgow Coma Scale in predicting outcome after traumatic brain injuryBrandon P Foreman
University of Texas Southwestern Medical Center at Dallas, USA
J Trauma 62:946-50. 2007..We aimed to analyze the usefulness of the head abbreviated injury score (AIS), the injury severity score (ISS), and the Glasgow Coma Scale (GCS) as measures of injury severity and predictors of outcome after traumatic brain injury (TBI)... - Gender differences in the performance of a computerized version of the alcohol use disorders identification test in subcritically injured patients who are admitted to the emergency departmentTim Neumann
Department of Anesthesiology and Intensive Care Medicine, Charite University Medicine, Campus Mitte, Schumannstrasse 20 21, 10117 Berlin, Germany
Alcohol Clin Exp Res 28:1693-701. 2004..An additional purpose of the study was to determine whether computerized screening for alcohol problems is feasible in this setting... - Let's diagnose alcohol problems in the emergency department and successfully interveneLarry M Gentilello
MedGenMed 8:1. 2006 - Comparison of trauma center patient self-reports and proxy reports on the Alcohol Use Identification Test (AUDIT)Dennis M Donovan
University of Washington Alcohol and Drug Abuse Institute, University of Washington School of Medicine Seattle, WA 98105 4631, USA
J Trauma 56:873-82. 2004..The present study evaluated the level of agreement between trauma patients' self-report and proxy report on the Alcohol Use Disorders Identification Test (AUDIT)...