Robert Genco

Summary

Affiliation: University at Buffalo
Country: USA

Publications

  1. ncbi request reprint Common risk factors in the management of periodontal and associated systemic diseases: the dental setting and interprofessional collaboration
    Robert J Genco
    Office of Science, Technology Transfer and Economic Outreach, State University of New York at Buffalo, Baird Research Park, Amherst, NY 14228, USA Electronic address
    J Evid Based Dent Pract 14:4-16. 2014
  2. ncbi request reprint Screening for diabetes mellitus in dental practices: a field trial
    Robert J Genco
    Dr Genco is a SUNY distinguished professor and vice provost, State University of New York at Buffalo, Baird Research Park, Suite 103, 1576 Sweet Home Road, Amherst, N Y 14228
    J Am Dent Assoc 145:57-64. 2014
  3. ncbi request reprint Validity of self-reported measures for surveillance of periodontal disease in two western New York population-based studies
    Robert J Genco
    Department of Oral Biology, School of Dental Medicine, State University of New York at Buffalo, Buffalo, New York 14228, USA
    J Periodontol 78:1439-54. 2007
  4. ncbi request reprint A proposed model linking inflammation to obesity, diabetes, and periodontal infections
    Robert J Genco
    Department of Oral Biology, School of Dental Medicine, Office of Science, Technology Transfer, and Economic Outreach STOR, University at Buffalo, Buffalo, NY 14228, USA
    J Periodontol 76:2075-84. 2005
  5. doi request reprint Prevention: Reducing the risk of CVD in patients with periodontitis
    Robert J Genco
    Department of Oral Biology, State University of New York at Buffalo, Baird Research Park, 1576 Sweet Home Road, Amherst, NY 14228, USA
    Nat Rev Cardiol 7:479-80. 2010
  6. ncbi request reprint Periodontal disease and cardiovascular disease: epidemiology and possible mechanisms
    Robert Genco
    Department of Oral Biology, State University of New York at Buffalo, 3435 Main St, Foster Hall, Buffalo, N Y 14214 3008, USA
    J Am Dent Assoc 133:14S-22S. 2002
  7. ncbi request reprint Association of increased levels of fibrinogen and the -455G/A fibrinogen gene polymorphism with chronic periodontitis
    Sinem E Sahingur
    Department of Oral Biology, School of Dental Medicine, University at Buffalo, Buffalo, NY 14214, USA
    J Periodontol 74:329-37. 2003
  8. ncbi request reprint The association between osteoporosis and alveolar crestal height in postmenopausal women
    Jean Wactawski-Wende
    Department of Social and Preventive Medicine, School of Public Health and Health Professions, University at Buffalo, Buffalo, NY 14214, USA
    J Periodontol 76:2116-24. 2005
  9. ncbi request reprint Supragingival plaque may modify the effects of subgingival bacteria on attachment loss
    Mine Tezal
    Department of Oral Biology, State University of New York, Buffalo, NY 14214, USA
    J Periodontol 77:808-13. 2006
  10. ncbi request reprint The use of different measurements and definitions of periodontal disease in the study of the association between periodontal disease and risk of myocardial infarction
    Oelisoa M Andriankaja
    School of Public Health and Health Professions, University at Buffalo, NY 14214, USA
    J Periodontol 77:1067-73. 2006

Collaborators

Detail Information

Publications39

  1. ncbi request reprint Common risk factors in the management of periodontal and associated systemic diseases: the dental setting and interprofessional collaboration
    Robert J Genco
    Office of Science, Technology Transfer and Economic Outreach, State University of New York at Buffalo, Baird Research Park, Amherst, NY 14228, USA Electronic address
    J Evid Based Dent Pract 14:4-16. 2014
    ..There is a role for dentistry in the interprofessional management of chronic diseases by addressing common risk factors..
  2. ncbi request reprint Screening for diabetes mellitus in dental practices: a field trial
    Robert J Genco
    Dr Genco is a SUNY distinguished professor and vice provost, State University of New York at Buffalo, Baird Research Park, Suite 103, 1576 Sweet Home Road, Amherst, N Y 14228
    J Am Dent Assoc 145:57-64. 2014
    ..In this field trial, the authors assess the feasibility of screening for diabetes and prediabetes in dental practices and in a community health center...
  3. ncbi request reprint Validity of self-reported measures for surveillance of periodontal disease in two western New York population-based studies
    Robert J Genco
    Department of Oral Biology, School of Dental Medicine, State University of New York at Buffalo, Buffalo, New York 14228, USA
    J Periodontol 78:1439-54. 2007
    ..We sought to assess the feasibility of self-reported periodontal disease measures using dental history questions combined with demographic and medical history to predict periodontal disease...
  4. ncbi request reprint A proposed model linking inflammation to obesity, diabetes, and periodontal infections
    Robert J Genco
    Department of Oral Biology, School of Dental Medicine, Office of Science, Technology Transfer, and Economic Outreach STOR, University at Buffalo, Buffalo, NY 14228, USA
    J Periodontol 76:2075-84. 2005
    ....
  5. doi request reprint Prevention: Reducing the risk of CVD in patients with periodontitis
    Robert J Genco
    Department of Oral Biology, State University of New York at Buffalo, Baird Research Park, 1576 Sweet Home Road, Amherst, NY 14228, USA
    Nat Rev Cardiol 7:479-80. 2010
    ..Oliveira et al. have added lack of oral hygiene, and its link with systemic inflammation, to the spectrum of risk factors for CVD...
  6. ncbi request reprint Periodontal disease and cardiovascular disease: epidemiology and possible mechanisms
    Robert Genco
    Department of Oral Biology, State University of New York at Buffalo, 3435 Main St, Foster Hall, Buffalo, N Y 14214 3008, USA
    J Am Dent Assoc 133:14S-22S. 2002
    ..This report summarizes the evidence from epidemiologic studies and studies that focused on potential contributing mechanisms to provide a more complete picture of the association between periodontal and heart disease...
  7. ncbi request reprint Association of increased levels of fibrinogen and the -455G/A fibrinogen gene polymorphism with chronic periodontitis
    Sinem E Sahingur
    Department of Oral Biology, School of Dental Medicine, University at Buffalo, Buffalo, NY 14214, USA
    J Periodontol 74:329-37. 2003
    ..In this study, we investigated the distribution of the -455G/A polymorphism and the relationship of this specific genotype to fibrinogen levels in periodontitis patients...
  8. ncbi request reprint The association between osteoporosis and alveolar crestal height in postmenopausal women
    Jean Wactawski-Wende
    Department of Social and Preventive Medicine, School of Public Health and Health Professions, University at Buffalo, Buffalo, NY 14214, USA
    J Periodontol 76:2116-24. 2005
    ..Evidence supporting an association between osteoporosis and loss of alveolar crestal bone is limited. This study investigated that association in a large cohort of postmenopausal women...
  9. ncbi request reprint Supragingival plaque may modify the effects of subgingival bacteria on attachment loss
    Mine Tezal
    Department of Oral Biology, State University of New York, Buffalo, NY 14214, USA
    J Periodontol 77:808-13. 2006
    ..This study evaluates the role of supragingival plaque level on the relationship between subgingival microorganisms and the risk of attachment loss...
  10. ncbi request reprint The use of different measurements and definitions of periodontal disease in the study of the association between periodontal disease and risk of myocardial infarction
    Oelisoa M Andriankaja
    School of Public Health and Health Professions, University at Buffalo, NY 14214, USA
    J Periodontol 77:1067-73. 2006
    ..The present study assesses if the observed association between periodontal disease and incident myocardial infarction (MI) depends on the measurements and/or criteria used to define periodontal disease...
  11. ncbi request reprint Bacterial species in subgingival plaque and oral bone loss in postmenopausal women
    Renee M Brennan
    Department of Social and Preventive Medicine, School of Public Health and Health Professions, University at Buffalo, State University of New York, Buffalo, NY 14212, USA
    J Periodontol 78:1051-61. 2007
    ....
  12. ncbi request reprint Periodontal disease and recurrent cardiovascular events in survivors of myocardial infarction (MI): the Western New York Acute MI Study
    Joan M Dorn
    Department of Social and Preventive Medicine, School of Public Health and Health Professions, State University of New York, University at Buffalo, Buffalo, NY, USA
    J Periodontol 81:502-11. 2010
    ..This study investigates whether periodontal disease is related to recurrent CVD events and mortality in survivors of incident myocardial infarction (MI)...
  13. ncbi request reprint Periodontal disease and risk of myocardial infarction: the role of gender and smoking
    Oelisoa Mireille Andriankaja
    Social and Preventive Medicine, SUNY at Buffalo, 3435 Main Street, Buffalo, NY, 14214, USA
    Eur J Epidemiol 22:699-705. 2007
    ..Limited data have been reported in women and the role of smoking has not been fully clarified...
  14. doi request reprint Clinical innovations in managing inflammation and periodontal diseases: the workshop on inflammation and periodontal diseases
    Robert J Genco
    Department of Oral Biology, School of Dental Medicine, State University of New York at Buffalo, 1576 Sweet Home Road, Amherst, NY 14228, USA
    J Periodontol 79:1609-11. 2008
  15. ncbi request reprint Clinical attachment loss, systemic bone density, and subgingival calculus in postmenopausal women
    Renee M Brennan
    Department of Social and Preventive Medicine, School of Public Health and Health Professions, University at Buffalo, State University of New York, Buffalo, NY 14214, USA
    J Periodontol 78:2104-11. 2007
    ..We investigated these associations in a relatively large study while evaluating potential confounding factors and effect modification by subgingival calculus and age...
  16. ncbi request reprint Periodontal disease and the incidence of tooth loss in postmenopausal women
    Mine Tezal
    Department of Oral Biology, University at Buffalo, Buffalo, NY, USA
    J Periodontol 76:1123-8. 2005
    ..The aim of this cohort study was to determine the extent of the association between baseline periodontal status and incident tooth loss in a population of postmenopausal women...
  17. pmc Porphyromonas gingivalis fimbriae bind to cytokeratin of epithelial cells
    Hakimuddin T Sojar
    Department of Oral Biology, School of Dental Medicine, State University of New York at Buffalo, Buffalo, New York 14214, USA
    Infect Immun 70:96-101. 2002
    ..gingivalis fimbriae. We hypothesize that adherence of P. gingivalis fimbriae to cytokeratin may be important for colonization of oral mucous membranes and possibly also for activation of epithelial cells...
  18. ncbi request reprint Alcohol consumption and periodontal disease. The Third National Health and Nutrition Examination Survey
    Mine Tezal
    Department of Oral Biology, State University of New York at Buffalo, School of Dental Medicine, Buffalo, NY 14214 3092, USA
    J Clin Periodontol 31:484-8. 2004
    ..This study was carried out to evaluate the effect of alcohol consumption on the severity of periodontal disease...
  19. ncbi request reprint Is periodontitis associated with oral neoplasms?
    Mine Tezal
    Department of Oral Biology, University at Buffalo, Buffalo, NY, USA
    J Periodontol 76:406-10. 2005
    ..Infections have been suggested in the etiology of oral cancer. This study was carried out to evaluate the effect of periodontal disease on oral soft tissue lesions...
  20. pmc Counteracting interactions between lipopolysaccharide molecules with differential activation of toll-like receptors
    George Hajishengallis
    Department of Oral Biology, State University of New York at Buffalo, 14214, USA
    Infect Immun 70:6658-64. 2002
    ..Interactions between TLR2 and TLR4 agonists may be important in the regulation of inflammatory reactions...
  21. ncbi request reprint Identification of glyceraldehyde-3-phosphate dehydrogenase of epithelial cells as a second molecule that binds to Porphyromonas gingivalis fimbriae
    Hakimuddin T Sojar
    Department of Oral Biology, School of Dental Medicine, State University of New York at Buffalo, 213 Foster Hall, 3435 Main Street, Buffalo, NY 14214 3092, USA
    FEMS Immunol Med Microbiol 45:25-30. 2005
    ..gingivalis major fimbriae and, as such, GAPDH likely plays a role in P. gingivalis adherence and colonization of the oral cavity, as well as triggering host cell processes involved in the pathogenesis of P. gingivalis infections...
  22. ncbi request reprint Interactions of oral pathogens with toll-like receptors: possible role in atherosclerosis
    George Hajishengallis
    Department of Oral Biology, University at Buffalo, Buffalo, New York, USA
    Ann Periodontol 7:72-8. 2002
    ....
  23. pmc Dependence of bacterial protein adhesins on toll-like receptors for proinflammatory cytokine induction
    George Hajishengallis
    Department of Oral Biology, State University of New York at Buffalo, Buffalo, New York 14214, USA
    Clin Diagn Lab Immunol 9:403-11. 2002
    ..Our data suggest that the CD14-TLR2/4 system is involved in cytokine production and tolerance induction upon interaction with certain proinflammatory bacterial protein adhesins...
  24. ncbi request reprint Porphyromonas gingivalis fimbriae binds to neoglycoproteins: evidence for a lectin-like interaction
    Hakimuddin T Sojar
    Department of Oral Biology, School of Dental Medicine, State University of New York at Buffalo, 213 Foster Hall, 3435 Main Street, Buffalo, NY 14214 3092, USA
    Biochimie 86:245-9. 2004
    ..This protein-carbohydrate interactions may be important for triggering events in these cells, which mediate the host response of this pathogen...
  25. pmc Systemic inflammation in cardiovascular and periodontal disease: comparative study
    Ingrid Glurich
    Department of Oral Biology, State University of New York at Buffalo, 14214, USA
    Clin Diagn Lab Immunol 9:425-32. 2002
    ..The data support the hypothesis that localized persistent infection may influence systemic levels of inflammatory mediators. Changes in inflammatory mediator levels potentially impact inflammation-associated atherosclerotic processes...
  26. pmc Identification and characterization of a novel adhesin unique to oral fusobacteria
    Yiping W Han
    Department of Biological Sciences, School of Dental Medicine, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, OH 44106 4905, USA
    J Bacteriol 187:5330-40. 2005
    ..Furthermore, due to its uniqueness to oral Fusobacterium species, fadA may be used as a marker to detect orally related fusobacteria. F. nucleatum isolated from other parts of the body may originate from the oral cavity...
  27. ncbi request reprint CDC Periodontal Disease Surveillance Project could help states plug data gaps
    William Maas
    Division of Oral Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA, USA
    J Periodontol 78:1178. 2007
  28. ncbi request reprint Platelet-derived growth factor stimulates bone fill and rate of attachment level gain: results of a large multicenter randomized controlled trial
    Myron Nevins
    Harvard School of Dental Medicine, Boston, MA, USA
    J Periodontol 76:2205-15. 2005
    ....
  29. pmc Downregulation of the DNA-binding activity of nuclear factor-kappaB p65 subunit in Porphyromonas gingivalis fimbria-induced tolerance
    George Hajishengallis
    Department of Microbiology, Immunology, and Parasitology, Center of Excellence in Oral and Craniofacial Biology, Louisiana State University Health Sciences Center, New Orleans, Louisiana 70119, USA
    Infect Immun 72:1188-91. 2004
    ..Moreover, expression of a NF-kappaB-dependent reporter gene was inhibited upon secondary stimulation with fimbriae. NF-kappaB p65 downregulation may thus contribute to induction of FimA tolerance...
  30. ncbi request reprint The Periodontitis and Vascular Events (PAVE) pilot study: recruitment, retention, and community care controls
    David J Couper
    Department of Biostatistics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27514, USA
    J Periodontol 79:80-9. 2008
    ....
  31. ncbi request reprint Association of Fcgamma receptor IIa genotype with chronic periodontitis in Caucasians
    Kouji Yamamoto
    Division of Periodontology, Department of Oral Biological Science, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan
    J Periodontol 75:517-22. 2004
    ..The aim of this study is to examine whether FcgammaRIIa polymorphism is associated with a disease risk as well...
  32. ncbi request reprint Intracellular signaling and cytokine induction upon interactions of Porphyromonas gingivalis fimbriae with pattern-recognition receptors
    George Hajishengallis
    Center of Excellence in Oral and Craniofacial Biology, Department of Microbiology, Immunology, and Parasitology, Louisiana State University Health Sciences Center, New Orleans, Louisiana 70119, USA
    Immunol Invest 33:157-72. 2004
    ..gingivalis fimbriae is essential for developing molecular approaches to control P. gingivalis-induced inflammatory responses in periodontal disease and perhaps atherosclerosis...
  33. ncbi request reprint CDC Periodontal Disease Surveillance Project: background, objectives, and progress report
    Paul I Eke
    Division of Oral Health, Surveillance, Investigations and Research Team, National Centers for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA
    J Periodontol 78:1366-71. 2007
    ..This workgroup was convened in 2003 as part of a CDC periodontal disease surveillance project...
  34. ncbi request reprint New composite endpoints to assess efficacy in periodontal therapy clinical trials
    Samuel E Lynch
    BioMimetic Therapeutics, Franklin, TN 37067, USA
    J Periodontol 77:1314-22. 2006
    ..To address this need, two composite endpoint alternatives are offered as a yardstick for clinical success; each includes the improvement in CAL and either improvement in linear bone growth or percent bone fill...
  35. ncbi request reprint Reproducibility of probing depth measurement using a constant-force electronic probe: analysis of inter- and intraexaminer variability
    Marcelo W B Araujo
    Dental Research and Graduate Studies Division, Department of Periodontics, Guarulhos University, Sao Paulo, SP, Brazil
    J Periodontol 74:1736-40. 2003
    ..The objective of our study was to evaluate inter- and intraexaminer variability of PD measurements among study examiners using a constant force periodontal probe, and to compare the variability of tooth-mean and quadrant-mean...
  36. ncbi request reprint The Periodontitis and Vascular Events (PAVE) pilot study: adverse events
    James D Beck
    Department of Dental Ecology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
    J Periodontol 79:90-6. 2008
    ..This article describes the occurrence of adverse events during the pilot study...
  37. ncbi request reprint Bob Genco: a life in periodontology
    D Walter Cohen
    University of Pennsylvania School of Dental Medicine, Philadelphia, PA, USA
    J Periodontol 76:2031-2. 2005
  38. ncbi request reprint Effect of periodontitis on overt nephropathy and end-stage renal disease in type 2 diabetes
    Wendy A Shultis
    Diabetes Epidemiology and Clinical Research Section, Phoenix Epidemiology and Clinical Research Branch, National Institutes of Health, 1550 E Indian School Rd, Phoenix, AZ 85014 4972, USA
    Diabetes Care 30:306-11. 2007
    ..The purpose of this study was to investigate the effect of periodontitis on development of overt nephropathy, defined as macroalbuminuria, and end-stage renal disease (ESRD) in type 2 diabetes...

Research Grants6

  1. PERIODONTAL INFECTION AND RISK FOR MYOCARDIAL INFARCTION
    Robert Genco; Fiscal Year: 1999
    ..Therefore, understanding the association between these two diseases is of significant importance, both to individuals and for public health measures directed to reducing their morbidity and mortality. ..
  2. PERIODONTAL INFECTION AND RISK FOR MYOCARDIAL INFARCTION
    Robert Genco; Fiscal Year: 2000
    ..Therefore, understanding the association between these two diseases is of significant importance, both to individuals and for public health measures directed to reducing their morbidity and mortality. ..
  3. PERIODONTAL INFECTION AND RISK FOR MYOCARDIAL INFARCTION
    Robert Genco; Fiscal Year: 2001
    ..Therefore, understanding the association between these two diseases is of significant importance, both to individuals and for public health measures directed to reducing their morbidity and mortality. ..
  4. PERIODONTAL INTERVENTION FOR CARDIAC EVENTS: PILOT TRIAL
    Robert Genco; Fiscal Year: 2003
    ..abstract_text> ..