Research Topics
| James GeeSummaryAffiliation: University of Pennsylvania Country: USA Publications
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Detail Information
Publications
Resolving sentence ambiguity with planning and working memory resources: Evidence from fMRISusana Novais Santos
Department of Bioengineering, University of Pennsylvania, USA
Neuroimage 37:361-78. 2007..These findings are consistent with a large-scale neural network for sentence processing that recruits distinct planning and working memory processing resources as needed to support the comprehension of sentences...
Hierarchical organization of scripts: converging evidence from FMRI and frontotemporal degenerationChristine Farag
Department of Neurology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 4283, USA
Cereb Cortex 20:2453-63. 2010..Our findings suggest that frontal cortex contributes to clustering events during script comprehension, underlining the role of frontal cortex in the hierarchical organization of a script...- Alzheimer's disease and frontotemporal dementia exhibit distinct atrophy-behavior correlates: a computer-assisted imaging studyJames Gee
Department of Radiology, University of Pennsylvania, 3600 Market Street, Suite 370, Philadelphia, PA 19104 2644, USA
Acad Radiol 10:1392-401. 2003..The purpose of this study was to test the hypothesis that distinct patterns of gray matter atrophy are responsible for unique interruptions of the naming process in Alzheimer's disease (AD) and frontotemporal dementia (FTD)... - Large-scale neural network for sentence processingAyanna Cooke
Department of Neurology, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
Brain Lang 96:14-36. 2006.... - Neural basis for sentence comprehension deficits in frontotemporal dementiaAyanna Cooke
Department of Neurology-2 Gibson, University of Pennsylvania Medical Center, 3400 Spruce Street, Philadelphia, PA 19104-4283, USA
Brain Lang 85:211-21. 2003..We conclude that FTD subgroups have distinct patterns of sentence comprehension difficulty in part because of selective interruptions of a large-scale neural network for sentence processing... - Neural representation of verb meaning: an fMRI studyMurray Grossman
Department of Neurology, University of Pennsylvania, Philadelphia, Pennsylvania 19104 4283, USA
Hum Brain Mapp 15:124-34. 2002..We suggest that left posterolateral temporal activation supports aspects of lexical semantic processing concerned with the neural representation of propositional knowledge contributing to COGNITION verbs... - The neural basis for category-specific knowledge: an fMRI studyMurray Grossman
Department of Neurology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
Neuroimage 15:936-48. 2002.... - What's in a name: voxel-based morphometric analyses of MRI and naming difficulty in Alzheimer's disease, frontotemporal dementia and corticobasal degenerationMurray Grossman
Department of Neurology, University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19104 4283, USA
Brain 127:628-49. 2004..These findings are consistent with the hypothesis that a large-scale neural network supports naming, and that this network is interrupted in several distinct ways in patients with neurodegenerative diseases... - Cerebrospinal fluid profile in frontotemporal dementia and Alzheimer's diseaseMurray Grossman
Department of Neurology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 4283, USA
Ann Neurol 57:721-9. 2005..We conclude that CSF tau levels are significantly reduced in many patients with FTD... - Confrontation naming and morphometric analyses of structural MRI in frontotemporal dementiaCorey McMillan
Department of Neurology, University of Pennsylvania, Philadelphia, PA, USA
Dement Geriatr Cogn Disord 17:320-3. 2004..These findings suggest that confrontation naming is supported by a large-scale neural network, and that naming is compromised in FTD due to interruption of the network in several different ways... - Sentence processing strategies in healthy seniors with poor comprehension: an fMRI studyMurray Grossman
Department of Neurology, University of Pennsylvania, Philadelphia, USA
Brain Lang 80:296-313. 2002..Moreover, these observations emphasize the crucial role of the left perisylvian network for grammatically guided sentence processing in subjects with good comprehension... - Regional structural characterization of the brain of schizophrenia patientsPaul Yushkevich
Department of Radiology, 3600 Market Street, Suite 370, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
Acad Radiol 12:1250-61. 2005..We study morphologic characteristics and age-related changes in patients with schizophrenia to investigate whether abnormal neurodevelopment and brain structure have a role in the pathophysiological course of this disease... - Characterization of brain plasticity in schizophrenia using template deformationAbraham Dubb
Department of Bioengineering, University of Pennsylvania, Philadelphia, PA 19104, USA
Acad Radiol 12:3-9. 2005..Abnormal neurodevelopment may play a role in the pathophysiology of schizophrenia. We used deformation-based morphometry to examine voxel-wise age-related changes in patients with schizophrenia compared with healthy brains... - Speech errors in progressive non-fluent aphasiaSharon Ash
Department of Neurology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 4283, USA
Brain Lang 113:13-20. 2010..We conclude that the speech errors produced by PNFA patients are mainly errors at the phonemic level of language processing and are not caused by a motor planning impairment... - Neuroanatomy of apathy and disinhibition in frontotemporal lobar degenerationLauren Massimo
Department of Neurology, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
Dement Geriatr Cogn Disord 27:96-104. 2009..To investigate the neural basis for the behavioral symptoms of frontotemporal lobar degeneration (FTLD) that cause the greatest caregiver distress... - Medial temporal structures and memory functions in adolescents with heavy cannabis useManzar Ashtari
Department of Radiology, Children s Hospital of Philadelphia, Philadelphia, PA 19102, USA
J Psychiatr Res 45:1055-66. 2011.... - Spinal cord diffusion tensor imaging and fiber tracking can identify white matter tract disruption and glial scar orientation following lateral funiculotomyEric D Schwartz
Department of Radiology, University of Pennsylvania School of Medicine, 1 Silverstein, 3400 Spruce Street, Philadelphia, PA 19104, USA
J Neurotrauma 22:1388-98. 2005..In summary, DTI identified not only white matter disruption following injury, but could distinguish the orientation of the accompanying glial scar... - The shape operator for differential analysis of imagesBrian Avants
University of Pennsylvania, Philadelphia, PA 19104 6389, USA
Inf Process Med Imaging 18:101-13. 2003..A novel variant of Demons registration, extensible for use with differentiable similarity metrics, is also applied for deformable curvature-driven registration of medical images... - Characterization of sexual dimorphism in the human corpus callosumAbraham Dubb
Department of Bioengineering, Psychiatry, and Radiology, University of Pennsylvania, Philadelphia, PA 19104 6389, USA
Neuroimage 20:512-9. 2003..Our results demonstrate significant morphologic differences in the corpus callosum between genders and a possible sex difference in the neuro-developmental cycle... - How do registration parameters affect quantitation of lung kinematics?Tessa Sundaram Cook
Dept of Radiology, University of Pennsylvania, Philadelphia, PA, USA
Med Image Comput Comput Assist Interv 10:817-24. 2007..We intend to use the results of these experiments to more effectively and efficiently quantify pulmonary kinematics in future, and to explore additional parameter combinations... - Adaptive multi-cluster fuzzy C-means segmentation of breast parenchymal tissue in digital mammographyBrad Keller
Department of Radiology, University of Pennsylvania, Philadelphia, PA, USA
Med Image Comput Comput Assist Interv 14:562-9. 2011..83 (p<0.001) and an average Jaccard spatial similarity coefficient of 0.62. These results show promise for the clinical application of the algorithm in quantifying breast density in a repeatable manner... - Volumetric, connective, and morphologic changes in the brains of children with chromosome 22q11.2 deletion syndrome: an integrative studyTony J Simon
Children s Hospital of Philadelphia, 3535 Market Street, Room 1425, Philadelphia, PA 19104, USA
Neuroimage 25:169-80. 2005.... - Age-related changes in working memory during sentence comprehension: an fMRI studyMurray Grossman
Department of Neurology, University of Pennsylvania, Philadelphia, Pennsylvania 19104-4283, USA
Neuroimage 15:302-17. 2002..Seniors with good comprehension appear to up-regulate portions of the neural substrate for WM during sentence processing to achieve comprehension accuracy that equals young subjects... 
Accuracy of the cylinder approximation for susceptometric measurement of intravascular oxygen saturationCheng Li
Department of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
Magn Reson Med 67:808-13. 2012..In conclusion, the simulation results provide a significant level of confidence for the validity of the cylinder approximation underlying MR susceptometry-based oximetry of large vessels...- Altered resting cerebral blood flow in adolescents with in utero cocaine exposure revealed by perfusion functional MRIHengyi Rao
Department of Radiology and Neurology, Center for Functional Neuroimaging, University of Pennsylvania, Philadelphia, Pennsylvania, USA
Pediatrics 120:e1245-54. 2007.... - Neural basis for sentence comprehension: grammatical and short-term memory componentsAyanna Cooke
Department of Neurology, University of Pennsylvania Medical Center, Philadelphia, Pennsylvania 19104 4283, USA
Hum Brain Mapp 15:80-94. 2002.... - Validation of plaster endocast morphology through 3D CT image analysisP Thomas Schoenemann
Department of Behavioral Sciences, University of Michigan Dearborn, Dearborn, MI 48128, USA
Am J Phys Anthropol 132:183-92. 2007..This study gives an idea of the size of possible error inherent in latex/plaster endocasts, indicating the level of confidence we can have with studies relying on comparisons between them and, e.g., hominid fossil endocasts...