Research Topics
Species | Jeffrey J GaynorSummaryAffiliation: University of Miami Country: USA Publications
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Publications
A cause-specific hazard rate analysis of prognostic factors among 877 adults who received primary orthotopic liver transplantationJeffrey J Gaynor
Department of Surgery, University of Miami School of Medicine, Miami, FL, 33101, USA
Transplantation 84:155-65. 2007..Prognostic factors for one failure type may be distinctly different from those predictive of other types, and an accurate portrayal of these relationships may more clearly explain each factor's importance...
The importance of analyzing graft and patient survival by cause of failure: an example using pediatric small intestine transplant dataJeffrey J Gaynor
Department of Surgery, University of Miami School of Medicine, Miami, FL33101, USA
Transplantation 81:1133-40. 2006..The use of a cause-specific hazard (CSH) approach may provide more precise identification and thus greater insight as to why certain factors are prognostically important...
Campath-1H induction therapy in African American and Hispanic first renal transplant recipients: 3-year actuarial follow-upGaetano Ciancio
Lillian Jean Kaplan Renal Transplant Center, Division of Transplantation, Department of Surgery, University of Miami Miller School of Medicine, Miami, FL 33101, USA
Transplantation 85:507-16. 2008..In a retrospective study of the first 75 primary renal transplant patients given alemtuzumab induction at our center, 20 were African American (27%), 32 were Hispanic (43%), and 23 were non-African American, non-Hispanic (31%)...
Randomized trial of mycophenolate mofetil versus enteric-coated mycophenolate sodium in primary renal transplant recipients given tacrolimus and daclizumab/thymoglobulin: one year follow-upGaetano Ciancio
The Lillian Jean Kaplan Renal Transplant Center of the Division of Transplantation, Department of Surgery, University of Miami Miller School of Medicine, Miami, FL, USA
Transplantation 86:67-74. 2008..It was of interest to compare enteric-coated mycophenolate sodium (EC-MPS) versus mycophenolate mofetil (MMF) among renal transplant recipients receiving a tacrolimus-based immunosuppressive regimen...
A randomized trial of thymoglobulin vs. alemtuzumab (with lower dose maintenance immunosuppression) vs. daclizumab in renal transplantation at 24 months of follow-upGaetano Ciancio
Department of Surgery, The Lillian Jean Kaplan Renal Transplant Center of the Division of Transplantation, University of Miami Leonard M Miller School of Medicine, Miami, FL 33101, USA
Clin Transplant 22:200-10. 2008..A long-term prospective randomized trial evaluating alemtuzumab, a humanized anti-CD52 monoclonal antibody, in a predominantly non-Caucasian population has yet to be reported...
The use of Campath-1H as induction therapy in renal transplantation: preliminary resultsGaetano Ciancio
Department of Surgery, Division of Transplantation, University of Miami School of Medicine, Miami, FL 33101, USA
Transplantation 78:426-33. 2004....
Randomized trial of immunosuppressive regimens in renal transplantationGiselle Guerra
Department of Medicine, Division of Nephrology, University of Miami Miller School of Medicine, P O Box 012440 R 440, Miami, FL 33101, USA
J Am Soc Nephrol 22:1758-68. 2011..Taken together, these results suggest that maintenance therapy with tacrolimus/MMF is more favorable than either tacrolimus/sirolimus or cyclosporine/sirolimus...
Randomized trial of dual antibody induction therapy with steroid avoidance in renal transplantationGaetano Ciancio
Department of Surgery, University of Miami Miller School of Medicine, Miami, FL, USA
Transplantation 92:1348-57. 2011..Given our previous experience using dual-induction therapy with antithymocyte globulin (ATG)/daclizumab (Dac) (each with fewer doses than if used alone), we chose to compare two distinct dual-induction strategies...
A randomized trial of three renal transplant induction antibodies: early comparison of tacrolimus, mycophenolate mofetil, and steroid dosing, and newer immune-monitoringGaetano Ciancio
Dept of Surgery, The Lillian Jean Kaplan Renal Transplant Center of the Division of Transplantation, University of Miami Leonard M Miller School of Medicine, and the Miami Veterans Affairs Medical Center, Miami, Florida 33101, USA
Transplantation 80:457-65. 2005..New trends in immunosuppression in clinical transplantation include the use of antibody induction agents in protocols that emphasize reduction or avoidance of steroids and calcineurin inhibitors...
A randomized long-term trial of tacrolimus/sirolimus versus tacrolimums/mycophenolate versus cyclosporine/sirolimus in renal transplantation: three-year analysisGaetano Ciancio
The Lillian Jean Kaplan Renal Transplant Center, Department of Surgery, Division of Transplantation, University of Miami Miller School of Medicine, PO Box 012440, Miami, FL 33101, USA
Transplantation 81:845-52. 2006..We report three-year (interim) effects of combining sirolimus (Siro) vs. mycophenolate mofetil (MMF) as adjunctive therapy with calcineurin inhibitors (CI) in renal transplantation in the three different CI-based regimens...
A randomized long-term trial of tacrolimus/sirolimus versus tacrolimus/mycophenolate mofetil versus cyclosporine (NEORAL)/sirolimus in renal transplantation. II. Survival, function, and protocol compliance at 1 yearGaetano Ciancio
Department of Surgery, Division of Transplantation, University of Miami School of Medicine, Miami, FL 33101, USA
Transplantation 77:252-8. 2004..Adjunctive Siro therapy with a similar dose reduction algorithm for Neoral (Neo) was included for comparison...
100 multivisceral transplants at a single centerAndreas G Tzakis
Department of Surgery, University of Miami Miller School of Medicine, Miami, Florida 33136, USA
Ann Surg 242:480-90; discussion 491-3. 2005..Our results show that the multivisceral graft seems to facilitate engraftment of transplanted organs and raises the possibility that there is a degree of immunologic protection afforded by this procedure...
Addition of anti-CD25 to thymoglobulin for induction therapy: delayed return of peripheral blood CD25-positive populationJunichiro Sageshima
Division of Kidney and Pancreas Transplantation, Department of Surgery, University of Miami, Miller School of Medicine, 1801 NW 9th Ave, 5th Fl, Miami, FL 33136, USA
Clin Transplant 25:E132-5. 2011..This strategy may result in reduced allogeneic (donor-specific) T effector cells at the time of solid organ transplantation...
Randomized trial of mycophenolate mofetil versus enteric-coated mycophenolate sodium in primary renal transplantation with tacrolimus and steroid avoidance: four-year analysisGaetano Ciancio
The Lillian Jean Kaplan Renal Transplant Center of the Division of Transplantation, Department of Surgery, University of Miami Miller School of Medicine, Miami, FL 33101, USA
Transplantation 91:1198-205. 2011..This report includes 3 additional years of follow-up with similar endpoints as in the original study...
Randomized trial of steroid-free induction versus corticosteroid maintenance among orthotopic liver transplant recipients with hepatitis C virus: impact on hepatic fibrosis progression at one yearTomoaki Kato
Department of Surgery, University of Miami School of Medicine, Miami, FL, USA
Transplantation 84:829-35. 2007..Due to the known high recurrence rate of hepatitis C virus (HCV) among orthotopic liver transplant (OLT) recipients who receive tacrolimus+corticosteroid maintenance, use of steroid-free induction was considered...
Effect of kidney transplantation on outcomes among patients with hepatitis CDavid Roth
Division of Nephrology and Hypertension, University of Miami Miller School of Medicine, Miami, FL 33136, USA
J Am Soc Nephrol 22:1152-60. 2011..Nevertheless, the higher incidence of early infection-related deaths after transplant calls for further study to determine the optimal immunosuppressive protocol...
Inclusion of donor colon and ileocecal valve in intestinal transplantationTomoaki Kato
Miami Transplant Institute, University of Miami, Miller School of Medicine, Miami, FL, USA
Transplantation 86:293-7. 2008..Evaluation of the clinical impact of including donor colon and ileocecal valve in patients receiving primary intestinal transplantation has not been performed in a sufficiently large series of cases...
Transplantation of the spleen: effect of splenic allograft in human multivisceral transplantationTomoaki Kato
Departments of Surgery, University of Miami, Miller School of Medicine, Miami, Florida 33136, USA
Ann Surg 246:436-44; discussion 445-6. 2007..To describe the effect of the splenic allograft in human multivisceral transplantation...
Prolonged lymphocyte depletion by single-dose rabbit anti-thymocyte globulin and alemtuzumab in kidney transplantationJunichiro Sageshima
DeWitt Daughtry Family Department of Surgery, University of Miami Leonard M Miller School of Medicine, Miami, Florida 33136, USA
Transpl Immunol 25:104-11. 2011..Overall, with extensive and persistent lymphocyte suppression by a simple administration of agents, single-dose rATG+C1H induction can be an alternative in renal transplantation...
Subclinical rejection in the initial postoperative period in small intestinal transplantation: a negative influence on graft survivalHidenori Takahashi
Department of Surgery, Division of Liver Gastrointestinal Transplant, University of Miami School of Medicine, Miami, FL 33136, USA
Transplantation 84:689-96. 2007..Subclinical rejection (SCR) is a known entity in various solid organ transplants but not in intestinal transplantation...
Disparities among Blacks, Hispanics, and Whites in time from starting dialysis to kidney transplant waitlistingShivam Joshi
Miami Transplant Institute, Department of Surgery, University of Miami Miller School of Medicine, Miami, FL 33101, USA
Transplantation 95:309-18. 2013..Although a longer time on dialysis before kidney transplant waitlisting has been shown for Blacks versus non-Blacks, relatively few studies have compared this outcome between Hispanics and Whites...
Favorable outcomes with machine perfusion and longer pump times in kidney transplantation: a single-center, observational studyGaetano Ciancio
Leonard M Miller School of Medicine, University of Miami, Miami, FL, USA
Transplantation 90:882-90. 2010..Because a lack of consensus regarding optimal use of MP still exists, we evaluated the overall impact of using MP at our center and the prognostic value of MP (Pump) time...
Blood citrulline level is an exclusionary marker for significant acute rejection after intestinal transplantationAndre I David
Departments of Surgery, University of Miami School of Medicine, Miami, FL 33101, USA
Transplantation 84:1077-81. 2007....
Intestinal transplantation in children: a summary of clinical outcomes and prognostic factors in 108 patients from a single centerTomoaki Kato
Division of Transplantation, University of Miami, School of Medicine, Miami, Florida 33136, USA
J Gastrointest Surg 9:75-89; discussion 89. 2005..A protective effect of multivisceral transplantation appears to exist with respect to the development of severe rejection...
Herpes zoster infection after liver transplantation in patients receiving induction therapy with alemtuzumabMaria L Alcaide
Department of Infectious Diseases, Miller School of Medicine, Miami, FL 33136, USA
Clin Transplant 22:502-7. 2008..2-18%. We studied the occurrence of HZ in liver transplant recipients that received induction therapy with alemtuzumab (Campath 1H)...
Utilization of dried blood spot citrulline level as a noninvasive method for monitoring graft function following intestinal transplantationHee Chul Yu
Department of Surgery, Division of Transplantation, University of Miami School of Medicine, Miami, FL 33136, USA
Transplantation 80:1729-33. 2005..CONCLUSIONS: DBS citrulline monitoring will ease sample collection following intestinal transplantation and improve the ability to detect intestinal dysfunction and rejection by a noninvasive means...
Intestinal and multivisceral transplantation in childrenTomoaki Kato
Department of Surgery, University of Miami School of Medicine, 1801 NW 9th Avenue, Miami, FL 33136, USA
Ann Surg 243:756-64; discussion 764-6. 2006..To describe a single-center experience of pediatric intestinal transplantation (Itx) and to provide an overview of the children who underwent this procedure along with their outcomes...
Outcomes after orthotopic liver transplantation in 15 HIV-infected patientsIan Schreibman
Center for Liver Diseases, Division of Hepatology, University of Miami Leonard M Miller School of Medicine, Miami, FL 33136, USA
Transplantation 84:697-705. 2007..Highly active antiretroviral therapy (HAART) has led to an increasing number of successful OLTs. The aim of this study was to examine survival and cause-specific mortality in HIV-infected patients after OLT at our institution...
Preliminary experience with alemtuzumab (Campath-1H) and low-dose tacrolimus immunosuppression in adult liver transplantationAndreas G Tzakis
Department of Surgery, Division of Transplantation, University of Miami School of Medicine, Miami, Florida 33136, USA
Transplantation 77:1209-14. 2004..We report our preliminary experience with C1H and tacrolimus (Tac) immunosuppression in adult liver transplantation...
Machine perfusion following static cold storage preservation in kidney transplantation: donor-matched pair analysis of the prognostic impact of longer pump timeGaetano Ciancio
The Lillian Jean Kaplan Renal Transplant Center, Leonard M Miller School of Medicine, University of Miami, FL 33101, USA
Transpl Int 25:34-40. 2012..While offering significantly favorable protection from BPAR, this analysis of donor-matched recipient pairs corroborates longer MP (pump) times having no unfavorable effect on other clinical outcomes...
FoxP3 mRNA transcripts and regulatory cells in renal transplant recipients 10 years after donor marrow infusionRobert E Cirocco
Department of Surgery, The Lillian Jean Kaplan Renal Transplant Center of the Division of Transplantation, University of Miami Leonard M Miller School of Medicine, Miami, FL 33101, USA
Transplantation 83:1611-9. 2007..We questioned if this was associated with putatively regulatory FoxP3 mRNA and cell phenotypes (CD4+CD25+high percentages and high DC2:DC1 ratios) in DBMC-i vs. noninfused controls...
Negative impact of new-onset diabetes mellitus on patient and graft survival after liver transplantation: Long-term follow upJang I Moon
Department of Surgery, University of Miami Leonard M Miller School of Medicine, Miami, FL, USA
Transplantation 82:1625-8. 2006..Little is known about the long-term consequences of new-onset diabetes mellitus (NODM) after liver transplantation (LTX)...
An analysis of the association between serum citrulline and acute rejection among 26 recipients of intestinal transplantPeter A Pappas
University of Miami/Jackson Memorial Hospital, Department of Surgery, Division of Transplantation, Miami, FL USA
Am J Transplant 4:1124-32. 2004..We plan to further examine the use of citrulline as a marker for rejection in larger prospective studies...
Competing risks analysis of predictors of delisting owing to tumor progression in liver transplant candidates with hepatocellular carcinomaNoriyo Yamashiki
Division of Transplantation, Department of Surgery, University of Miami School of Medicine, Miami, FL, USA
Am J Transplant 4:774-81. 2004..001). In conclusion, the initial AFP level may be useful along with tumor stage in defining an urgency score for liver transplant candidates with HCC...
Secondhand smoke and earaches in adolescents: the Florida Youth Cohort StudyDavid J Lee
University of Miami, Tobacco Research and Evaluation Coordinating Center, Sylvester Comprehensive Cancer Center, Miami, FL 33101, USA
Nicotine Tob Res 5:943-6. 2003..05). Second-hand smoke exposure is associated with self-reported earaches in adolescents. These findings should be replicated in a study in which clinical measures of middle ear function are performed...
Inhibition of NF-kappa B during human dendritic cell differentiation generates anergy and regulatory T-cell activity for one but not two human leukocyte antigen DR mismatchesAna Hernandez
Department of Surgery, Division of Transplantation, University of Miami School of Medicine, Miami, FL, USA
Hum Immunol 68:715-29. 2007..Extension of this study to human organ transplantation suggests potential therapies using one DR-matched NF-kappaB blocked DC to help generate clinical tolerance...
A randomized long-term trial of tacrolimus and sirolimus versus tacrolimus and mycophenolate mofetil versus cyclosporine (NEORAL) and sirolimus in renal transplantation. I. Drug interactions and rejection at one yearGaetano Ciancio
Department of Surgery, Division of Transplantation, University of Miami School of Medicine, Miami, Florida 33101, USA
Transplantation 77:244-51. 2004....
