Research Topics
Species | P G GaugerSummaryAffiliation: University of Michigan Country: USA Publications
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Detail Information
Publications
Incidence and importance of the tubercle of Zuckerkandl in thyroid surgeryP G Gauger
Department of Surgery, University of Michigan Hospital, Ann Arbor, USA
Eur J Surg 167:249-54. 2001..To define the incidence of a distinct tubercle of Zuckerkandl (TZ) and confirm its anatomical relationships with the recurrent laryngeal nerve and the superior parathyroid gland...- Initial use of a novel instrument to measure professionalism in surgical residentsPaul G Gauger
Department of Surgery, Division of Endocrine Surgery, 1500 E Medical Center Dr, Taubman Center TC2920H, Ann Arbor, MI 48109 0331, USA
Am J Surg 189:479-87. 2005..No universally accepted method to measure professionalism exists. We developed an instrument to measure specific aspects of professionalism in surgical residents... - Role of endoscopic ultrasonography in screening and treatment of pancreatic endocrine tumours in asymptomatic patients with multiple endocrine neoplasia type 1P G Gauger
Division of Endocrine Surgery and Section of Gastroenterology, University of Michigan, Ann Arbor, Michigan 48109 0331, USA
Br J Surg 90:748-54. 2003..Endoscopic ultrasonography (EUS) is the most sensitive imaging modality for small PETs. A screening and therapeutic approach for asymptomatic patients is delineated in which EUS plays a pivotal role... - An alternative analysis of intraoperative parathyroid hormone data may improve the ability to detect multiglandular diseasePaul G Gauger
Division of Endocrine Surgery, Department of Surgery, University of Michigan Medical School, Ann Arbor, USA
Arch Surg 139:164-9. 2004..A nomogram based on regression analysis of intraoperative parathyroid hormone level decay discriminates single gland disease from multiglandular (MG) disease more accurately than the currently used 50% rule... - Intraoperative parathyroid hormone monitoring fails to detect double parathyroid adenomas: a 2-institution experienceP G Gauger
University of Michigan Department of Surgery, Ann Arbor, MI, USA
Surgery 130:1005-10. 2001..These data suggest that caution should be exercised when terminating limited parathyroid exploration based on a curative fall in IOPTH values... 
Laparoscopic skills are improved with LapMentor training: results of a randomized, double-blinded studyPamela B Andreatta
Department of Medical Education, University of Michigan, Ann Arbor, MI 48109, USA
Ann Surg 243:854-60; discussion 860-3. 2006..This work marks the first prospective, randomized evaluation of the LapMentor simulator, and provides evidence that LapMentor training may lead to improved operating room performance...- Early surgical intervention and strategy in patients with multiple endocrine neoplasia type 1P G Gauger
Department of Surgery, Division of Endocrine Surgery, University of Michigan Hospital, Ann Arbor, Michigan, USA
Best Pract Res Clin Endocrinol Metab 15:213-23. 2001..Many patients may be completely cured of the manifestations of their disease. As MEN-1 is an uncommon entity, there are very few prospective, randomized data upon which to base surgical judgements... 
The role of PET in the surgical approach to adrenal diseaseM D Gross
Department of Radiology, Division of Nuclear Medicine, University of Michigan Medical Center and Department of Veterans Affairs Health System, Ann Arbor, Michigan USA
Eur J Surg Oncol 35:1137-45. 2009....- Propofol decreases early postoperative nausea and vomiting in patients undergoing thyroid and parathyroid operationsPaul G Gauger
Department of Surgery, Division of Endocrine Surgery, University of Michigan Medical School, 1500 East Medical Center Drive, TC 2920D, Ann Arbor, MI 48109 0331, USA
World J Surg 32:1525-34. 2008..The purpose of this study was to determine whether anesthetic technique based on propofol decreases the incidence of PONV and, consequently, improves patient satisfaction with their care... - The so-called stunning of thyroid tissueJames C Sisson
Department of Radiology, Division of Nuclear Medicine, University of Michigan Health System, Ann Arbor, 48109 0028, USA
J Nucl Med 47:1406-12. 2006..We hypothesized that stunning arose from the early effects of the therapeutic dose of (131)I and that the initial uptake of (131)I, observed within the first day, was not impaired by the diagnostic dose... - Trends in utilization of adrenalectomy in the United States: have indications changed?Brian D Saunders
Division of Endocrine Surgery, Department of Surgery, University of Michigan Medical Center, Ann Arbor, Michigan 48109, USA
World J Surg 28:1169-75. 2004..Assuming no significant change in disease prevalence during the study period, these data suggest that indications for adrenalectomy may have changed somewhat over that period... - Thyroid lymphoma arising from Hashimoto's thyroiditisBarbra S Miller
Department of General Surgery, Division of Endocrine Surgery, University of Michigan Health System, 2920 Taubman Health Care Center, 1500 East Medical Center Drive, Ann Arbor, MI 48109-0331, USA
J Clin Endocrinol Metab 91:3711-2. 2006 - Revisiting lithium-associated hyperparathyroidism in the era of intraoperative parathyroid hormone monitoringJonathan C Hundley
Division of Endocrine Surgery, Department of Surgery, University of Michigan, Ann Arbor, MI 48109-0331, USA
Surgery 138:1027-31; discussion 1031-2. 2005..The ability of IOPTH to predict durable normocalcemia is limited. Bilateral neck exploration should be considered for these patients regardless of whether IOPTH monitoring is used... - Influence of prophylactic central lymph node dissection on postoperative thyroglobulin levels and radioiodine treatment in papillary thyroid cancerDavid T Hughes
Department of Surgery, University of Michigan, Ann Arbor, MI 48109, USA
Surgery 148:1100-6; discussion 1006-7. 2010..The purpose of this study is to determine whether prophylactic central neck dissection provides any advantages over TT alone... - LapMentor metrics possess limited construct validityPamela B Andreatta
Department of Medical Education and Surgery, University of Michigan, Ann Arbor, Michigan 48109 5329, USA
Simul Healthc 3:16-25. 2008..The ability of a metric to differentiate novice from expert performance is referred to as construct validity. The present study was undertaken to determine whether the LapMentor's metrics demonstrate construct validity... - Proposal for modification of the ENSAT staging system for adrenocortical carcinoma using tumor gradeBarbra S Miller
Division of Endocrine Surgery, University of Michigan, Ann Arbor, MI, USA
Langenbecks Arch Surg 395:955-61. 2010..We hypothesized that incorporating tumor grade into the current European Network for the Study of Adrenal Tumors (ENSAT) staging system would improve the ability to more accurately predict time to recurrence and death... - An international perspective on ultrasound training and use for thyroid and parathyroid diseaseBarbra S Miller
Division of Endocrine Surgery, University of Michigan, Ann Arbor, MI 48109, USA
World J Surg 34:1157-63. 2010..We hypothesized that in more recent years fellowship-trained endocrine surgeons were more likely to receive formal training in the use of USN during their endocrine surgery fellowship... - Completion pancreatectomy and duodenectomy for recurrent MEN-1 pancreaticoduodenal endocrine neoplasmsPaul G Gauger
Division of Endocrine Surgery, University of Michigan Department of Surgery, Ann Arbor, MI 48109 0331, USA
Surgery 146:801-6; discussion 807-8. 2009.... - Laparoscopic simulation training with proficiency targets improves practice and performance of novice surgeonsPaul G Gauger
Department of Surgery, University of Michigan Medical School, Ann Arbor, MI, USA
Am J Surg 199:72-80. 2010..This study compares a laparoscopic skill training protocol without proficiency targets to the same protocol with explicit targets and notification of progress... - Distinct transcriptional profiles of adrenocortical tumors uncovered by DNA microarray analysisThomas J Giordano
Departments of Pathology, Pediatrics, Surgery, and Biostatistics, University of Michigan Health System, Ann Arbor, Michigan 48109 0054, USA
Am J Pathol 162:521-31. 2003..Moreover, we identified several genes that represent potential diagnostic markers and may play a role in the pathogenesis of ACC... - Molecular classification and prognostication of adrenocortical tumors by transcriptome profilingThomas J Giordano
Department of Pathology, 1150 West Medical Center Drive, MSRB 2, C570D, Ann Arbor, MI 48109 0669, USA
Clin Cancer Res 15:668-76. 2009..For instance, can molecular subtypes of ACC be identified? If so, what is their underlying pathogenetic basis and do they possess clinical significance?.. - Gender differences in the self-assessment of surgical residentsRebecca M Minter
Department of Surgery, University of Michigan Medical School, 1500 E Medical Center Dr, Ann Arbor, MI 48109, USA
Am J Surg 189:647-50. 2005..Despite equivalent performance as assessed by objective external measures, women tend to underestimate their abilities compared with their male counterparts... - Laparoscopic resection is inappropriate in patients with known or suspected adrenocortical carcinomaB S Miller
Division of Endocrine Surgery, University of Michigan, 2920F Taubman Center, 1500 E Medical Center Drive, Ann Arbor, MI 48109, USA
World J Surg 34:1380-5. 2010..Use of laparoscopy has been questioned in patients with ACC. This study compares the outcomes of patients undergoing laparoscopic versus open resection (OR) for ACC... - Endocrine tumours of the pancreas: review and recent advancesM H Mullan
Department of Surgery, Division of Endocrine Surgery, University of Michigan Hospital, Ann Arbor 48109-0331, USA
ANZ J Surg 71:475-82. 2001..The present article will review the various classes of PET, describe MEN-1 in relation to PET and examine advances in imaging and localization. The role of surgery for PET is also discussed in the present review... - Microarray analysis of cytokine activation of apoptosis pathways in the thyroidSu He Wang
Department of Medicine, University of Michigan Medical School, Ann Arbor, MI 48109 0648, USA
Endocrinology 148:4844-52. 2007..This hints that inflammatory cytokines regulate death-receptor-mediated apoptosis at multiple points in the process... - Construct validity of the LapSim laparoscopic surgical simulatorDerek T Woodrum
Department of Surgery, University of Michigan, 1500 E. Medical Center Drive, 2920 Taubman Center, Ann Arbor, MI 48109-0331, USA
Am J Surg 191:28-32. 2006..However, some performance parameters do not differentiate between groups. To accurately measure a trainee's skill level, only parameters that sensitively measure the true level of performance should be used... - Role of 131I in the treatment of well differentiated thyroid cancerDerek T Woodrum
Division of Endocrine Surgery, University of Michigan Department of Surgery, Ann Arbor, Michigan, USA
J Surg Oncol 89:114-21. 2005..For these cancers, redifferentiation therapy and molecular target-specific medicines hold future promise for improved treatment... - The surgical management of MEN-1 pancreatoduodenal neuroendocrine diseaseMark S Hausman
Division of Endocrine Surgery, Department of Surgery, University of Michigan, Taubman Center, 1500 East Medical Center Drive, Ann Arbor, MI 48109-0331, USA
Surgery 136:1205-11. 2004..Most patients (22 of 39) eventually demonstrated malignant growth, but, with this strategy, few died of this disease... - Who performs endocrine operations in the United States?Brian D Saunders
Department of Surgery, Divisions of Endocrine Surgery and Vascular Surgery, University of Michigan, 1500 E Medical Center Drive, Taubman Center 2920H, Ann Arbor, MI 48109 0331, USA
Surgery 134:924-31; discussion 931. 2003..Endocrine surgery is a discipline that is dedicated to high-quality care of patients with endocrine surgical disease. The relationship between its "identity" as a separate field and clinical practice patterns is not known... - The influence of sample site on intraoperative PTH monitoring during parathyroidectomyDerek T Woodrum
Department of Surgery, University of Michigan, Taubman Center TC2920H, 1500 East Medical Center Drive, Ann Arbor, MI 48109-0331, USA
Surgery 136:1169-75. 2004..Consequently, CV IOPTH levels are generally higher at 10 minutes, but this discrepancy resolves by 15 minutes. The surgeon utilizing CV samples may need to extend the sampling period... - Management of patients with adrenal cancer: recommendations of an international consensus conferenceD E Schteingart
Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, USA
Endocr Relat Cancer 12:667-80. 2005..Anti-angiogenic substances have only been applied in preclinical studies. The use of these and other agents in the treatment of adrenal cancer should be hypothesis-driven and based on a thorough analysis of tumor biology... - IFNgamma sensitization to TRAIL-induced apoptosis in human thyroid carcinoma cells by upregulating Bak expressionSu He Wang
Department of Medicine, University of Michigan Medical Center, Ann Arbor, MI, USA
Oncogene 23:928-35. 2004..This suggests that Bak is a regulatory molecule involved in IFNgamma-facilitated TRAIL-mediated apoptosis in thyroid cancer cells... - Evidence-based surgical management of substernal goiterMatthew L White
Division of Endocrine Surgery, Department of Surgery, University of Michigan, 2920 Taubman Center, 1500 East Medical Center Drive, Ann Arbor, MI 48109 0331, USA
World J Surg 32:1285-300. 2008..A number of reports have been published concerning the surgical treatment of substernal goiters; however, there is yet to be a comprehensive review of this body of literature using evidence-based methodology... - Appearance of ectopic undescended inferior parathyroid adenomas on technetium Tc 99m sestamibi scintigraphy: a lesson from reoperative parathyroidectomyDavid Axelrod
Department of Surgery, University of Michigan Medical School, Ann Arbor, USA
Arch Surg 138:1214-8. 2003..After corroboration, this finding may facilitate a targeted operation... - Central lymph node dissection in differentiated thyroid cancerMatthew L White
Department of Surgery, University of Michigan, Ann Arbor, MI 48109, USA
World J Surg 31:895-904. 2007..A comprehensive review of this body of literature using evidence-based methodology is pending... - Anaplastic thyroid cancer manifesting as new-onset Horner syndromeJames T Broome
Department of Surgery, Section of General Surgery, Division of Endocrine Surgery, University of Michigan, Ann Arbor, Michigan, USA
Endocr Pract 15:563-6. 2009..To report a case of Horner syndrome as the initial sign of locally advanced anaplastic thyroid cancer... - Aberrant apoptosis in thyroid epithelial cells from goiter nodulesEmese Mezosi
Department of Medicine, University of Michigan Medical Center, Ann Arbor, Michigan 48109-0648, USA
J Clin Endocrinol Metab 87:4264-72. 2002..The increased proteasome activity associated with this resistance suggests that the proteasome may be an important regulator of apoptosis in nodular goiter... - The role of radiologic studies in the evaluation and management of primary hyperaldosteronismMatthew L White
Division of Endocrine Surgery, Department of Surgery, University of Michigan, Ann Arbor, Mich, USA
Surgery 144:926-33; discussion 933. 2008..Surgical treatment of primary hyperaldosteronism (PHA) requires demonstration of unilateral adrenal hypersecretion. Optimal methods for interpretation of imaging and invasive testing are still in development... - Inflammatory cytokine regulation of TRAIL-mediated apoptosis in thyroid epithelial cellsJ D Bretz
Department of Medicine, University of Michigan Medical Center, Ann Arbor, Michigan, USA
Cell Death Differ 9:274-86. 2002..We also show the in vivo presence of TRAIL and TRAIL receptors DR5 and DcR1 in both normal and inflamed thyroids. Our data suggests TRAIL-mediated apoptosis may contribute to target organ destruction in chronic autoimmune thyroiditis... - Lithium therapy and hyperparathyroidism: an evidence-based assessmentBrian D Saunders
Department of Surgery, Pennsylvania State Milton S Hershey Medical Center, Penn State University College of Medicine, Mail Code H070, 500 University Drive, PO Box 850, Hershey, PA 17033 0850, USA
World J Surg 33:2314-23. 2009..A unique form of hyperparathyroidism appears to be causally linked to chronic lithium exposure. We provide a comprehensive review of relevant literature using a structured, evidence-based approach... - EUS detection of pancreatic endocrine tumors in asymptomatic patients with type 1 multiple endocrine neoplasiaErik-Jan Wamsteker
Department of Internal Medicine, The University of Michigan School of Medicine, Ann Arbor, Michigan 48109, USA
Gastrointest Endosc 58:531-5. 2003..Aggressive early surgical treatment may improve the prognosis for these patients... - Palliative thyroidectomy for malignant lymphoma of the thyroidRebecca S Sippel
Department of Surgery, University of Wisconsin Medical School, Madison, Wisconsin 53792, USA
Ann Surg Oncol 9:907-11. 2002..In this group of patients, thyroidectomy can be associated with good long-term palliation and low morbidity... - Pitfalls in the surgical treatment of insulinomaMelanie L Richards
University of Michigan Hospital, Ann Arbor, Michigan, USA
Surgery 132:1040-9; discussion 1049. 2002..By sharing our experience with recent difficult cases, we guide the surgeon to greater success and the patient to decreased morbidity... - Is preoperative iodine 123 meta-iodobenzylguanidine scintigraphy routinely necessary before initial adrenalectomy for pheochromocytoma?Judiann Miskulin
Department of Surgery, University of Michigan, 1500 E Medical Center Drive, Taubman Center TC2920H, Ann Arbor, MI 48109 0331, USA
Surgery 134:918-22; discussion 922-3. 2003..We sought to determine the role of (123)I MIBG scintigraphy in this apparently routine preoperative setting. Our hypothesis was that (123)I MIBG would provide additional preoperative information that could modify operative intervention... - Ganglioneuroma manifesting as an incidental adrenal mass in an adult with Turner's syndromeChad N Stasik
University of Michigan Medical School, University of Michigan, Ann Arbor, MI 48109, USA
Endocr Pract 11:382-4. 2005.... - Web-based curriculum improves residents' knowledge of health care businessLinnea S Hauge
University of Michigan Medical School, Department of Surgery, Ann Arbor, MI 48109 5346, USA
J Am Coll Surg 211:777-83. 2010..The purpose of this study is to describe surgery residents' experience and learning outcomes associated with the curriculum... - Resident participation does not affect surgical outcomes, despite introduction of new techniquesShaun P Patel
Department of Surgery, University of Michigan Medical School, Ann Arbor, MI 48109 0340, USA
J Am Coll Surg 211:540-5. 2010..There are few studies evaluating whether complication rates, independent of patient risk factors, are affected by resident participation in operations... - Metastatic papillary thyroid carcinoma causing hand weaknessJudian Miskulin
Department of Surgery, Division of Endocrine Surgery, University of Michigan, Ann Arbor, MI 48109, USA
Thyroid 12:433-4. 2002 - Induction and regulation of Fas-mediated apoptosis in human thyroid epithelial cellsEmese Mezosi
Department of Medicine, University of Michigan Medical Center, 9220 Medical Sciences Research Building III, 1150 West Medical Center Drive, Ann Arbor, Michigan 48109 0648, USA
Mol Endocrinol 19:804-11. 2005..This process involves Bcl-2 family proteins and appears to be compatible with type II apoptosis regulation... - The impact of primary hyperparathyroidism on the oral cavityAllan D Padbury
D.D.S, Department of Periodontics and Oral Medicine, University of Michigan, 1011 North University Avenue, Ann Arbor, Michigan 48109-1078, USA
J Clin Endocrinol Metab 91:3439-45. 2006..The contemporary oral manifestations of primary HPT are different from those previously reported, and health care providers should be aware of newer, more subtle findings that may be present when treating patients with HPT... - Interleukin-1beta and tumor necrosis factor (TNF)-alpha sensitize human thyroid epithelial cells to TNF-related apoptosis-inducing ligand-induced apoptosis through increases in procaspase-7 and bid, and the down-regulation of p44/42 mitogen-activated protEmese Mezosi
Center for Biologic Nanotechnology, University of Michigan Medical Center, Ann Arbor, Michigan 48109, USA
J Clin Endocrinol Metab 89:250-7. 2004.... - Interpretation of intraoperative parathyroid hormone monitoring in patients with baseline parathyroid hormone levels of <100 pg/mLBarbra S Miller
University of Texas Health Science Center, Division of General Surgery, MC7842, 7703 Floyd Curl Dr, San Antonio, TX 78229, USA
Surgery 140:883-9; discussion 889-90. 2006..We hypothesize that patients with low-baseline levels (<100 pg/mL) have a higher incidence of multigland disease (MGD) and display differences in PTH kinetics compared with patients with high-baseline levels... - Unilateral adrenal hyperplasiaPaul G Gauger
World J Surg 31:1716-7. 2007 - Impact of intraoperative parathyroid hormone monitoring on the prediction of multiglandular parathyroid diseaseThomas Clerici
Department of Surgery, Kantonsspital St Gallen, CH 9007 St Gallen, Switzerland
World J Surg 28:187-92. 2004..The importance of these findings must be further investigated, especially with regard to the outcome of minimally invasive parathyroid procedures... - Laparoscopic partial adrenalectomy for bilateral pheochromocytomasShih Ping Cheng
Department of Surgery, Mackay Memorial Hospital, Taipei, Taiwan
Ann Surg Oncol 15:2506-8. 2008..Partial adrenalectomy can preserve adrenal function to avoid the morbidity associated with medical adrenal replacement. Here, we report a multimedia case study of synchronous bilateral partial adrenalectomy by the laparoscopic approach... - Use of [18F]fluorodeoxyglucose positron emission tomography in evaluating locally recurrent and metastatic adrenocortical carcinomaGavin C Mackie
Department of Radiological Sciences, St. Jude Children's Research Hospital, 332 North Lauderdale, Mail Stop 752, Memphis, Tennessee 38105-2794, USA
J Clin Endocrinol Metab 91:2665-71. 2006..CONCLUSIONS: Most adrenocortical carcinomas accumulate and retain FDG and thus can be visualized by PET. However, false-negative findings are possible, especially with very small lesions...