Andrew D Gaudet
Affiliation: University of Colorado
Gaudet A, Mandrekar Colucci S, Hall J, Sweet D, Schmitt P, Xu X, et al
. miR-155 Deletion in Mice Overcomes Neuron-Intrinsic and Neuron-Extrinsic Barriers to Spinal Cord Repair. J Neurosci. 2016;36:8516-32 pubmed publisher
..Therefore, miR-155 has a dual role in regulating spinal cord repair and may be a novel therapeutic target for SCI and other CNS pathologies. ..
Gaudet A, Fonken L. Glial Cells Shape Pathology and Repair After Spinal Cord Injury. Neurotherapeutics. 2018;15:554-577 pubmed publisher
..Therefore, optimizing post-SCI responses of glial cells-and interactions between these CNS cells-could benefit neuroprotection, axon plasticity, and functional recovery. ..
Bateman E, Schleicher W, Smith E, Sweet D, Gaudet A. Journal Club: MRI reveals acute inflammation in cortical lesions during early MS. Neurology. 2018;90:e724-e726 pubmed publisher
..Their novel data suggest that acute inflammation after blood-brain barrier leakage may contribute to gray matter cortical lesions in early multiple sclerosis. ..
Gaudet A, Ayala M, Schleicher W, Smith E, Bateman E, Maier S, et al
. Exploring acute-to-chronic neuropathic pain in rats after contusion spinal cord injury. Exp Neurol. 2017;295:46-54 pubmed publisher
..Further, chronic neuropathic pain elicited by these contusion SCIs was not amplified by our course of early post-trauma morphine. Using clinically relevant rat models of SCI could help identify novel pain management strategies. ..