R S Gaston

Summary

Affiliation: University of Alabama at Birmingham
Country: USA

Publications

  1. doi request reprint Our evolving understanding of late kidney allograft failure
    Robert S Gaston
    University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
    Curr Opin Organ Transplant 16:594-9. 2011
  2. ncbi request reprint Improving access to renal transplantation
    Robert S Gaston
    Division of Nephrology, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
    Semin Dial 18:482-6. 2005
  3. ncbi request reprint Current and evolving immunosuppressive regimens in kidney transplantation
    Robert S Gaston
    Division of Nephrology, University of Alabama, School of Medicine, Birmingham, AL, USA
    Am J Kidney Dis 47:S3-21. 2006
  4. ncbi request reprint Limiting financial disincentives in live organ donation: a rational solution to the kidney shortage
    R S Gaston
    University of Alabama School of Medicine, Birmingham, Alabama, USA
    Am J Transplant 6:2548-55. 2006
  5. doi request reprint Fixed- or controlled-dose mycophenolate mofetil with standard- or reduced-dose calcineurin inhibitors: the Opticept trial
    R S Gaston
    University of Alabama at Birmingham, Birmingham, AL, USA
    Am J Transplant 9:1607-19. 2009
  6. doi request reprint Use of cardioprotective medications in kidney transplant recipients
    R S Gaston
    University of Alabama at Birmingham, Birmingham, AL, USA
    Am J Transplant 9:1811-5. 2009
  7. doi request reprint Chronic calcineurin inhibitor nephrotoxicity: reflections on an evolving paradigm
    Robert S Gaston
    Division of Nephrology, 625 THT, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    Clin J Am Soc Nephrol 4:2029-34. 2009
  8. doi request reprint Evidence for antibody-mediated injury as a major determinant of late kidney allograft failure
    Robert S Gaston
    Division of Nephrology, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    Transplantation 90:68-74. 2010
  9. ncbi request reprint Transplantation in the diabetic patient with advanced chronic kidney disease: a task force report
    Robert S Gaston
    Division of Nephrology, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    Am J Kidney Dis 44:529-42. 2004
  10. pmc Inflammation in areas of tubular atrophy in kidney allograft biopsies: a potent predictor of allograft failure
    R B Mannon
    Division of Nephrology, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA
    Am J Transplant 10:2066-73. 2010

Detail Information

Publications34

  1. doi request reprint Our evolving understanding of late kidney allograft failure
    Robert S Gaston
    University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
    Curr Opin Organ Transplant 16:594-9. 2011
    ..Dramatic improvement in short-term results after kidney transplantation has fostered a change in focus for clinical research: further improvement in patient outcomes requires better understanding of late allograft failure...
  2. ncbi request reprint Improving access to renal transplantation
    Robert S Gaston
    Division of Nephrology, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
    Semin Dial 18:482-6. 2005
    ..It also highlights potential solutions to overcome these newly recognized obstacles...
  3. ncbi request reprint Current and evolving immunosuppressive regimens in kidney transplantation
    Robert S Gaston
    Division of Nephrology, University of Alabama, School of Medicine, Birmingham, AL, USA
    Am J Kidney Dis 47:S3-21. 2006
    ..This article reviews current practice and recent studies to give all health care providers who manage kidney transplant recipients a better understanding of current regimens and general trends in immunosuppressive therapy...
  4. ncbi request reprint Limiting financial disincentives in live organ donation: a rational solution to the kidney shortage
    R S Gaston
    University of Alabama School of Medicine, Birmingham, Alabama, USA
    Am J Transplant 6:2548-55. 2006
    ..As importantly, by directly linking compensation to risk, we believe it preserves the essence of kidney donation as a gift, consistent with NOTA and implementable in the United States without altering current legal statutes...
  5. doi request reprint Fixed- or controlled-dose mycophenolate mofetil with standard- or reduced-dose calcineurin inhibitors: the Opticept trial
    R S Gaston
    University of Alabama at Birmingham, Birmingham, AL, USA
    Am J Transplant 9:1607-19. 2009
    ..Thus, MMF(CC) with low-dose CNI resulted in outcomes not inferior to those with standard CNI exposure and MMF(FD), indicating potential utility of MMF(CC) in CNI-sparing regimens...
  6. doi request reprint Use of cardioprotective medications in kidney transplant recipients
    R S Gaston
    University of Alabama at Birmingham, Birmingham, AL, USA
    Am J Transplant 9:1811-5. 2009
    ....
  7. doi request reprint Chronic calcineurin inhibitor nephrotoxicity: reflections on an evolving paradigm
    Robert S Gaston
    Division of Nephrology, 625 THT, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    Clin J Am Soc Nephrol 4:2029-34. 2009
    ....
  8. doi request reprint Evidence for antibody-mediated injury as a major determinant of late kidney allograft failure
    Robert S Gaston
    Division of Nephrology, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    Transplantation 90:68-74. 2010
    ..We studied recipients with new onset late kidney graft dysfunction (n=173) to determine the importance of C4d staining and circulating donor-specific antibody (DSA) in subsequent LGF...
  9. ncbi request reprint Transplantation in the diabetic patient with advanced chronic kidney disease: a task force report
    Robert S Gaston
    Division of Nephrology, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    Am J Kidney Dis 44:529-42. 2004
    ..This report summarizes the deliberations and recommendations of the task force...
  10. pmc Inflammation in areas of tubular atrophy in kidney allograft biopsies: a potent predictor of allograft failure
    R B Mannon
    Division of Nephrology, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA
    Am J Transplant 10:2066-73. 2010
    ..Phenotypic characterization of these inflammatory cells and appropriate treatment may ameliorate late allograft failure...
  11. ncbi request reprint Maintenance immunosuppression in the renal transplant recipient: an overview
    R S Gaston
    Division of Nephrology, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    Am J Kidney Dis 38:S25-35. 2001
    ..This review summarizes available data regarding current practices in maintenance immunosuppression, emphasizing issues that arise in day-to-day management of renal transplant recipients...
  12. ncbi request reprint Recommendations for the outpatient surveillance of renal transplant recipients. American Society of Transplantation
    B L Kasiske
    Division of Nephrology, Hennepin County Medical Center, University of Minnesota, Minneapolis 55415, USA
    J Am Soc Nephrol 11:S1-86. 2000
    ..It is hoped that these guidelines will provide a framework for additional discussion and research that will improve the care of renal transplant recipients...
  13. ncbi request reprint Kidney and pancreas transplantation
    Robert S Gaston
    University of Alabama at Birmingham, Birmingham, AL, USA
    Am J Transplant 3:64-77. 2003
  14. ncbi request reprint Postransplant lymphoproliferative disorder localized near the allograft in renal transplantation
    C E Kew
    Department of Medicine, The University of Alabama at Birmingham, 35294 0007, USA
    Transplantation 69:809-14. 2000
    ..Typically, PTLD is a proliferation of B-cells associated with Epstein-Barr virus (EBV) infection; it is said to be most often a systemic disease. Involvement occasionally is localized near the allograft...
  15. ncbi request reprint Racial disparities in renal allograft survival: a public health issue?
    Devin E Eckhoff
    Department of Surgery, University of Alabama at Birmingham, Birmingham, AL 35294 0007, USA
    J Am Coll Surg 204:894-902; discussion 902-3. 2007
    ..The purpose of this study was to examine both immunologic and nonimmunologic risk factors for allograft loss with a goal of defining targeted strategies to improve outcomes among African Americans...
  16. ncbi request reprint Association of CD20+ infiltrates with poorer clinical outcomes in acute cellular rejection of renal allografts
    Benjamin E Hippen
    Division of Nephrology, Department of Medicine, University of Alabama, Birmingham, Alabama, USA
    Am J Transplant 5:2248-52. 2005
    ..This study supports prospective identification of CD20-positive B-cell clusters in biopsy-proven rejection and offers a therapeutic rationale for a trial of monoclonal anti-CD20 antibody in such patients...
  17. pmc Optimizing medication adherence: an ongoing opportunity to improve outcomes after kidney transplantation
    Mary B Prendergast
    Department of Medicine, Division of Nephrology, 625 THT, University of Alabama at Birmingham, 1530 Third Avenue South, Birmingham, AL 35294 0006, USA
    Clin J Am Soc Nephrol 5:1305-11. 2010
    ..Further advances are likely to be dependent on improving interactions between patients and caregivers, broadening immunosuppressant availability, and newer therapeutics that move toward simpler regimens...
  18. ncbi request reprint Tolerance in renal transplantation after allogeneic bone marrow transplantation-6-year follow-up
    M T Sellers
    Department of Surgery, University of Alabama at Birmingham, 701 South 19th Street, LHRB-728, Birmingham, AL 35294-0007, USA
    Transplantation 71:1681-3. 2001
    ..All noninvasive parameters of graft function remain normal. This and similar reports prove that genetically disparate solid organs can coexist without pharmacological immunosuppression...
  19. ncbi request reprint African Americans and renal transplantation: disproportionate need, limited access, and impaired outcomes
    Carlton J Young
    Department of Surgery, Division of Transplantation, University of Alabama at Birmingham, 35294 0006, USA
    Am J Med Sci 323:94-9. 2002
    ..This imbalance, coupled with AA disproportionately representing those with ESRD, has kept AA disadvantaged compared with other races, especially whites...
  20. pmc Systolic dysfunction portends increased mortality among those waiting for renal transplant
    Angelo M de Mattos
    Divisions of Nephrology, University of Alabama at Birmingham, Birmingham, Alabama, USA
    J Am Soc Nephrol 19:1191-6. 2008
    ..43 to 2.07). In addition, a graded, reverse association between LVEF and mortality was identified. In conclusion, systolic dysfunction is strongly associated with mortality, in a graded manner, in renal transplant candidates...
  21. pmc Kidney transplantation as primary therapy for end-stage renal disease: a National Kidney Foundation/Kidney Disease Outcomes Quality Initiative (NKF/KDOQITM) conference
    Michael Abecassis
    Division of Nephrology, University of Alabama at Birmingham, 625 THT, 1900 University Boulevard, Birmingham, AL 35294, USA
    Clin J Am Soc Nephrol 3:471-80. 2008
    ..5% of incident patients with end-stage renal disease undergo transplantation as their initial modality of treatment, a figure largely unchanged for at least a decade...
  22. ncbi request reprint Determinants of cardiovascular mortality after renal transplantation: a role for cytomegalovirus?
    Roberto S N Kalil
    Departments of Medicine and Surgery, University of Alabama at Birmingham, Birmingham, AL, USA
    Am J Transplant 3:79-81. 2003
    ..Risk of cardiovascular death was greatest (p < 0.05) in patients with diabetes, advancing age, and CMV seropositivity. In renal transplant recipients, infection with CMV increases risk of death as a result of cardiovascular causes...
  23. doi request reprint The impact of left ventricular systolic dysfunction on survival after renal transplantation
    Andrew Siedlecki
    Division of Nephrology, Washington University, St Louis, MO 63110, USA
    Transplantation 84:1610-7. 2007
    ..We hypothesize that decreased LVEF at time of renal transplant evaluation is an independent risk factor for cardiac death and nonfatal events after transplant...
  24. ncbi request reprint Long-term deterioration of kidney allograft function
    Bertram L Kasiske
    Department of Medicine, University of Minnesota, Minneapolis, USA
    Am J Transplant 5:1405-14. 2005
    ..78 (0.64-0.95), p = 0.0110 during 1999-2002 (compared to 1984-1989). We conclude that the rate of decline in allograft function after kidney transplantation has improved, suggesting that stable, long-term function may be achievable...
  25. ncbi request reprint A report of the Lisbon Conference on the care of the kidney transplant recipient
    Mario Abbud-Filho
    Instituto de Urologia e Nefrologia and Medical School FAMERP, Sao Jose do Rio Preto SP, Brazil
    Transplantation 83:S1-22. 2007
  26. ncbi request reprint Diabetes mellitus after kidney transplantation
    Robert S Gaston
    Am J Transplant 3:512-3. 2003
  27. ncbi request reprint Kidneys from deceased donors: maximizing the value of a scarce resource
    Herwig Ulf Meier-Kriesche
    Department of Medicine, University of Florida, Gainesville, FL, USA
    Am J Transplant 5:1725-30. 2005
    ..5 billion dollars...
  28. ncbi request reprint Whither living donors?
    Robert S Gaston
    Am J Transplant 4:2-3. 2004
  29. ncbi request reprint Pharmacokinetics of daclizumab and mycophenolate mofetil with cyclosporine and steroids in renal transplantation
    Mark D Pescovitz
    Indiana University, Indianapolis, IN 46202, USA
    Clin Transplant 17:511-7. 2003
    ..The coadministration of daclizumab did not result in a pharmacokinetic interaction with MPA, the active metabolite of MMF...
  30. ncbi request reprint The relationship between ethnicity and outcomes in solid organ transplantation
    Robert S Gaston
    J Pediatr 147:721-3. 2005
  31. ncbi request reprint Addressing minority issues in renal transplantation: is more equitable access an achievable goal?
    Robert S Gaston
    Am J Transplant 2:1-3. 2002
  32. ncbi request reprint The nondirected live-kidney donor: ethical considerations and practice guidelines: A National Conference Report
    Patricia L Adams
    Wake Forest University School of Medicine, USA
    Transplantation 74:582-9. 2002
    ..Other ethical issues such as the use of prisoners as an NDD, compensation for the NDD, media involvement, and communication between the NDD and recipient are discussed...
  33. ncbi request reprint The report of a national conference on the wait list for kidney transplantation
    Robert S Gaston
    Harvard Medical School, Massachusetts General Hospital, Boston, MA 02114, USA
    Am J Transplant 3:775-85. 2003
    ..Each work group outlined problems and potential remedies within each area. This report summarized the issues and recommendations regarding the waiting list for kidney transplantation addressed in the Philadelphia meeting...
  34. ncbi request reprint Understanding the influence of ethnicity on renal allograft survival
    Carlton J Young
    Am J Transplant 5:2603-4. 2005