Research Topics
Species | R S GastonSummaryAffiliation: University of Alabama at Birmingham Country: USA Publications
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Detail Information
Publications
Our evolving understanding of late kidney allograft failureRobert S Gaston
University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
Curr Opin Organ Transplant 16:594-9. 2011..Dramatic improvement in short-term results after kidney transplantation has fostered a change in focus for clinical research: further improvement in patient outcomes requires better understanding of late allograft failure...
Improving access to renal transplantationRobert S Gaston
Division of Nephrology, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
Semin Dial 18:482-6. 2005..It also highlights potential solutions to overcome these newly recognized obstacles...- Current and evolving immunosuppressive regimens in kidney transplantationRobert S Gaston
Division of Nephrology, University of Alabama, School of Medicine, Birmingham, AL, USA
Am J Kidney Dis 47:S3-21. 2006..This article reviews current practice and recent studies to give all health care providers who manage kidney transplant recipients a better understanding of current regimens and general trends in immunosuppressive therapy... - Limiting financial disincentives in live organ donation: a rational solution to the kidney shortageR S Gaston
University of Alabama School of Medicine, Birmingham, Alabama, USA
Am J Transplant 6:2548-55. 2006..As importantly, by directly linking compensation to risk, we believe it preserves the essence of kidney donation as a gift, consistent with NOTA and implementable in the United States without altering current legal statutes... - Fixed- or controlled-dose mycophenolate mofetil with standard- or reduced-dose calcineurin inhibitors: the Opticept trialR S Gaston
University of Alabama at Birmingham, Birmingham, AL, USA
Am J Transplant 9:1607-19. 2009..Thus, MMF(CC) with low-dose CNI resulted in outcomes not inferior to those with standard CNI exposure and MMF(FD), indicating potential utility of MMF(CC) in CNI-sparing regimens... - Use of cardioprotective medications in kidney transplant recipientsR S Gaston
University of Alabama at Birmingham, Birmingham, AL, USA
Am J Transplant 9:1811-5. 2009.... - Chronic calcineurin inhibitor nephrotoxicity: reflections on an evolving paradigmRobert S Gaston
Division of Nephrology, 625 THT, University of Alabama at Birmingham, Birmingham, AL 35294, USA
Clin J Am Soc Nephrol 4:2029-34. 2009.... - Evidence for antibody-mediated injury as a major determinant of late kidney allograft failureRobert S Gaston
Division of Nephrology, University of Alabama at Birmingham, Birmingham, AL 35294, USA
Transplantation 90:68-74. 2010..We studied recipients with new onset late kidney graft dysfunction (n=173) to determine the importance of C4d staining and circulating donor-specific antibody (DSA) in subsequent LGF... - Transplantation in the diabetic patient with advanced chronic kidney disease: a task force reportRobert S Gaston
Division of Nephrology, University of Alabama at Birmingham, Birmingham, AL 35294, USA
Am J Kidney Dis 44:529-42. 2004..This report summarizes the deliberations and recommendations of the task force... 
Inflammation in areas of tubular atrophy in kidney allograft biopsies: a potent predictor of allograft failureR B Mannon
Division of Nephrology, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA
Am J Transplant 10:2066-73. 2010..Phenotypic characterization of these inflammatory cells and appropriate treatment may ameliorate late allograft failure...- Maintenance immunosuppression in the renal transplant recipient: an overviewR S Gaston
Division of Nephrology, University of Alabama at Birmingham, Birmingham, AL 35294, USA
Am J Kidney Dis 38:S25-35. 2001..This review summarizes available data regarding current practices in maintenance immunosuppression, emphasizing issues that arise in day-to-day management of renal transplant recipients... - Recommendations for the outpatient surveillance of renal transplant recipients. American Society of TransplantationB L Kasiske
Division of Nephrology, Hennepin County Medical Center, University of Minnesota, Minneapolis 55415, USA
J Am Soc Nephrol 11:S1-86. 2000..It is hoped that these guidelines will provide a framework for additional discussion and research that will improve the care of renal transplant recipients... - Kidney and pancreas transplantationRobert S Gaston
University of Alabama at Birmingham, Birmingham, AL, USA
Am J Transplant 3:64-77. 2003 - Postransplant lymphoproliferative disorder localized near the allograft in renal transplantationC E Kew
Department of Medicine, The University of Alabama at Birmingham, 35294 0007, USA
Transplantation 69:809-14. 2000..Typically, PTLD is a proliferation of B-cells associated with Epstein-Barr virus (EBV) infection; it is said to be most often a systemic disease. Involvement occasionally is localized near the allograft... - Racial disparities in renal allograft survival: a public health issue?Devin E Eckhoff
Department of Surgery, University of Alabama at Birmingham, Birmingham, AL 35294 0007, USA
J Am Coll Surg 204:894-902; discussion 902-3. 2007..The purpose of this study was to examine both immunologic and nonimmunologic risk factors for allograft loss with a goal of defining targeted strategies to improve outcomes among African Americans... - Association of CD20+ infiltrates with poorer clinical outcomes in acute cellular rejection of renal allograftsBenjamin E Hippen
Division of Nephrology, Department of Medicine, University of Alabama, Birmingham, Alabama, USA
Am J Transplant 5:2248-52. 2005..This study supports prospective identification of CD20-positive B-cell clusters in biopsy-proven rejection and offers a therapeutic rationale for a trial of monoclonal anti-CD20 antibody in such patients... - Optimizing medication adherence: an ongoing opportunity to improve outcomes after kidney transplantationMary B Prendergast
Department of Medicine, Division of Nephrology, 625 THT, University of Alabama at Birmingham, 1530 Third Avenue South, Birmingham, AL 35294 0006, USA
Clin J Am Soc Nephrol 5:1305-11. 2010..Further advances are likely to be dependent on improving interactions between patients and caregivers, broadening immunosuppressant availability, and newer therapeutics that move toward simpler regimens... - Tolerance in renal transplantation after allogeneic bone marrow transplantation-6-year follow-upM T Sellers
Department of Surgery, University of Alabama at Birmingham, 701 South 19th Street, LHRB-728, Birmingham, AL 35294-0007, USA
Transplantation 71:1681-3. 2001..All noninvasive parameters of graft function remain normal. This and similar reports prove that genetically disparate solid organs can coexist without pharmacological immunosuppression... - African Americans and renal transplantation: disproportionate need, limited access, and impaired outcomesCarlton J Young
Department of Surgery, Division of Transplantation, University of Alabama at Birmingham, 35294-0006, USA
Am J Med Sci 323:94-9. 2002..However, AA remain significantly disadvantaged in both access and outcomes compared with whites. Further evaluation of underlying causes and development of specific remedies is warranted... - Systolic dysfunction portends increased mortality among those waiting for renal transplantAngelo M de Mattos
Divisions of Nephrology, University of Alabama at Birmingham, Birmingham, Alabama, USA
J Am Soc Nephrol 19:1191-6. 2008..43 to 2.07). In addition, a graded, reverse association between LVEF and mortality was identified. In conclusion, systolic dysfunction is strongly associated with mortality, in a graded manner, in renal transplant candidates... - Kidney transplantation as primary therapy for end-stage renal disease: a National Kidney Foundation/Kidney Disease Outcomes Quality Initiative (NKF/KDOQITM) conferenceMichael Abecassis
Division of Nephrology, University of Alabama at Birmingham, 625 THT, 1900 University Boulevard, Birmingham, AL 35294, USA
Clin J Am Soc Nephrol 3:471-80. 2008..5% of incident patients with end-stage renal disease undergo transplantation as their initial modality of treatment, a figure largely unchanged for at least a decade... - Determinants of cardiovascular mortality after renal transplantation: a role for cytomegalovirus?Roberto S N Kalil
Departments of Medicine and Surgery, University of Alabama at Birmingham, Birmingham, AL, USA
Am J Transplant 3:79-81. 2003..Risk of cardiovascular death was greatest (p < 0.05) in patients with diabetes, advancing age, and CMV seropositivity. In renal transplant recipients, infection with CMV increases risk of death as a result of cardiovascular causes... - The impact of left ventricular systolic dysfunction on survival after renal transplantationAndrew Siedlecki
Division of Nephrology, Washington University, St Louis, MO 63110, USA
Transplantation 84:1610-7. 2007..We hypothesize that decreased LVEF at time of renal transplant evaluation is an independent risk factor for cardiac death and nonfatal events after transplant... - Long-term deterioration of kidney allograft functionBertram L Kasiske
Department of Medicine, University of Minnesota, Minneapolis, USA
Am J Transplant 5:1405-14. 2005..78 (0.64-0.95), p = 0.0110 during 1999-2002 (compared to 1984-1989). We conclude that the rate of decline in allograft function after kidney transplantation has improved, suggesting that stable, long-term function may be achievable... - A report of the Lisbon Conference on the care of the kidney transplant recipientMario Abbud-Filho
Instituto de Urologia e Nefrologia and Medical School - FAMERP, , Brazil
Transplantation 83:S1-22. 2007 - Diabetes mellitus after kidney transplantationRobert S Gaston
Am J Transplant 3:512-3. 2003 - Kidneys from deceased donors: maximizing the value of a scarce resourceHerwig Ulf Meier-Kriesche
Department of Medicine, University of Florida, Gainesville, FL, USA
Am J Transplant 5:1725-30. 2005..5 billion dollars... - Whither living donors?Robert S Gaston
Am J Transplant 4:2-3. 2004 - Pharmacokinetics of daclizumab and mycophenolate mofetil with cyclosporine and steroids in renal transplantationMark D Pescovitz
Indiana University, Indianapolis, IN 46202, USA
Clin Transplant 17:511-7. 2003..The coadministration of daclizumab did not result in a pharmacokinetic interaction with MPA, the active metabolite of MMF... - The relationship between ethnicity and outcomes in solid organ transplantationRobert S Gaston
J Pediatr 147:721-3. 2005 - Addressing minority issues in renal transplantation: is more equitable access an achievable goal?Robert S Gaston
Am J Transplant 2:1-3. 2002 - The nondirected live-kidney donor: ethical considerations and practice guidelines: A National Conference ReportPatricia L Adams
Wake Forest University School of Medicine, USA
Transplantation 74:582-9. 2002..Transplant centers that accept NDD should document an informed consent process that details donor risks, assures donor safety, and determines that the goals and expectations of the NDD and the recipient can be realized... - The report of a national conference on the wait list for kidney transplantationRobert S Gaston
Harvard Medical School, Massachusetts General Hospital, Boston, MA 02114, USA
Am J Transplant 3:775-85. 2003..Each work group outlined problems and potential remedies within each area. This report summarized the issues and recommendations regarding the waiting list for kidney transplantation addressed in the Philadelphia meeting... - Understanding the influence of ethnicity on renal allograft survivalCarlton J Young
Am J Transplant 5:2603-4. 2005