David L Garver
Affiliation: University of Louisville
- Cerebral cortical gray expansion associated with two second-generation antipsychoticsDavid L Garver
Department of Psychiatry and Behavioral Science, University of Louisville School of Medicine, Louisville, Kentucky, USA
Biol Psychiatry 58:62-6. 2005..SGAs demonstrate 5-HT2a antagonism. Differential effects of SGAs and FGAs on cortical gray volumes are explored herein...
- Evolution of antipsychotic intervention in the schizophrenic psychosisDavid L Garver
Seven Counties Services, Inc, University of Louisville School of Medicine, 3 East Mill Place, Louisville KY 40222, USA
Curr Drug Targets 7:1205-15. 2006..It is likely that the next generation of antipsychotics will act more directly and more specifically on such underlying neuropathology...
- Compromised myelin integrity during psychosis with repair during remission in drug-responding schizophreniaDavid L Garver
Seven Counties Services, Inc, Louisville, KY 4022, USA
Int J Neuropsychopharmacol 11:49-61. 2008..An antipsychotic drug-induced cascade may partially restore myelin integrity and functional connectivity concomitant with antipsychotic effects in such D-RS patients...
- State-related thalamic changes during antipsychotic treatment in schizophrenia: preliminary observationsSasa Strungas
Department of Psychiatry and Behavioral Science, University of Louisville School of Medicine, Medcenter One, Suite 340, 501 West Broadway, Louisville, KY 40202, USA
Psychiatry Res 124:121-4. 2003..75 and r(s)=0.82, respectively (both P<0.04)]...
- State-related changes in cerebral white matter may underlie psychosis exacerbationJames Christensen
Mental Health Service, Louisville Veterans Affairs Medical Center One, Suite 340, Louisville, KY 40202, USA
Psychiatry Res 130:71-8. 2004..Partial remission of symptoms may mark temporary reduction of an active, toxic process that interferes with information processing...
- Volume increases in striatum associated with positive symptom reduction in schizophrenia: a preliminary observationStephen Taylor
Department of Psychiatry and Behavioral Sciences, University of Louisville School of Medicine, Medical Center 1, Suite 340, Louisville, KY 40202, USA
Psychiatry Res 140:85-9. 2005..An increase in left striatum was not associated with drug treatment itself, but with a reduction of positive symptoms...
- Elevated interleukin-6 in the cerebrospinal fluid of a previously delineated schizophrenia subtypeDavid L Garver
Department of Psychiatry and Behavioral Science, University of Louisville School of Medicine, 500 S Preston Street, Bldg A Room 210, Louisville, KY 40202, USA
Neuropsychopharmacology 28:1515-20. 2003..017) and the controls (P=0.013). In addition to supporting the concept of heterogeneity in schizophrenia, this study also provides evidence that a central immune process may be occurring centrally in one subtype of schizophrenia...
- Genome scan meta-analysis of schizophrenia and bipolar disorder, part II: SchizophreniaCathryn M Lewis
Division of Genetics and Development, Guy s, King s and St Thomas School of Medicine, London, UK
Am J Hum Genet 73:34-48. 2003..There is greater consistency of linkage results across studies than has been previously recognized. The results suggest that some or all of these regions contain loci that increase susceptibility to schizophrenia in diverse populations...
- Thiobarbituric acid reactive substances in the cerebrospinal fluid in schizophreniaAndrew O Skinner
Department of Psychiatry and Behavioral Science University of Louisville School of Medicine, KY 40222, USA
Schizophr Res 76:83-7. 2005..The likely source of reported elevated plasma/serum TBARS in schizophrenia is therefore in the periphery. Degeneration of central neuronal membranes in schizophrenia is not supported by the present study...