Research Topics
Genomes and Genes
| D J GarrySummaryAffiliation: University of Texas Southwestern Medical Center Country: USA Publications
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Detail Information
Publications
Life without myoglobinD J Garry
Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas 75390 8573, USA
Cell Mol Life Sci 57:896-8. 2000..This unexpected result led us to reexamine existing paradigms regarding the function of myoglobin in striated muscle...
Myogenic stem cell function is impaired in mice lacking the forkhead/winged helix protein MNFD J Garry
Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
Proc Natl Acad Sci U S A 97:5416-21. 2000..Animals deficient in MNF may prove useful for evaluation of potential therapeutic interventions to promote muscle regeneration for patients having Duchenne's muscular dystrophy...
Adaptive mechanisms that preserve cardiac function in mice without myoglobinA P Meeson
Departments of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA
Circ Res 88:713-20. 2001....
Persistent expression of MNF identifies myogenic stem cells in postnatal musclesD J Garry
Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, 75235, USA
Dev Biol 188:280-94. 1997..These data identify MNF as a marker of quiescent satellite cells and suggest that downstream genes controlled by MNF serve to modulate proliferative growth or differentiation in this unique cell population...
The winged-helix/forkhead protein myocyte nuclear factor beta (MNF-beta) forms a co-repressor complex with mammalian sin3BQ Yang
Department of Internal Medicine, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, NB11 200, Dallas, TX 75390 8573, USA
Biochem J 345:335-43. 2000..Transcriptional repression by MNF-beta-mSin3 complexes may contribute to the co-ordination of cellular proliferation and terminal differentiation of myogenic precursor cells...
Functional and molecular adaptations in skeletal muscle of myoglobin-mutant miceR W Grange
Department of Physiology, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA
Am J Physiol Cell Physiol 281:C1487-94. 2001..These results demonstrate that mammalian organisms are capable of a broad spectrum of adaptive responses that can compensate for a potentially serious defect in cellular oxygen transport...
p21 is essential for normal myogenic progenitor cell function in regenerating skeletal muscleT J Hawke
Department of Internal Medicine, University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Blvd, Dallas, TX 75390 8573, USA
Am J Physiol Cell Physiol 285:C1019-27. 2003..On the basis of these findings, we propose that p21 is essential for the coordination of cell cycle exit and differentiation in the adult MPC population and that in the absence of p21, skeletal muscle regeneration is markedly impaired...
Mice without myoglobinD J Garry
Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas 75235, USA
Nature 395:905-8. 1998..These data show that myoglobin is not required to meet the metabolic requirements of pregnancy or exercise in a terrestrial mammal, and raise new questions about oxygen transport and metabolic regulation in working muscles...
Myogenic satellite cells: physiology to molecular biologyT J Hawke
Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA
J Appl Physiol 91:534-51. 2001..We conclude by highlighting the potential therapeutic uses of satellite cells and identifying future research goals for the study of satellite cell biology...
Temporospatial expression of the small HSP/alpha B-crystallin in cardiac and skeletal muscle during mouse developmentI J Benjamin
Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas 75235 8573, USA
Dev Dyn 208:75-84. 1997....
Differential expression of mitochondrial DNA replication factors in mammalian tissuesR A Schultz
Department of Pathology, University of Texas Southwestern Medical Center, Dallas, Texas 75235, USA
J Biol Chem 273:3447-51. 1998....
The ontogeny of aerobic and diving capacity in the skeletal muscles of Weddell sealsS B Kanatous
Department of Biology, Colorado State University, Fort Collins, CO 80523 1878, USA
J Exp Biol 211:2559-65. 2008..As these future elite divers mature, their skeletal muscles transform to a more sedentary state in order to maintain the low levels of aerobic metabolism associated with long-duration diving...
