Affiliation: University of Michigan
Garg P, Rabelink T. Glomerular proteinuria: a complex interplay between unique players. Adv Chronic Kidney Dis. 2011;18:233-42 pubmed publisher
..In this review, we have attempted to present some of the prevailing understanding of the underlying mechanisms and physiology of proteinuria. ..
Verma R, Venkatareddy M, Kalinowski A, Patel S, Salant D, Garg P. Shp2 Associates with and Enhances Nephrin Tyrosine Phosphorylation and Is Necessary for Foot Process Spreading in Mouse Models of Podocyte Injury. Mol Cell Biol. 2016;36:596-614 pubmed publisher
..Taken together, these results suggest that Shp2-dependent signaling events are necessary for changes in foot process structure and function following injury. ..
Venkatareddy M, Verma R, Kalinowski A, Patel S, Shisheva A, Garg P. Distinct Requirements for Vacuolar Protein Sorting 34 Downstream Effector Phosphatidylinositol 3-Phosphate 5-Kinase in Podocytes Versus Proximal Tubular Cells. J Am Soc Nephrol. 2016;27:2702-19 pubmed publisher
..In summary, these data suggest that glomerular podocytes and proximal tubules have different requirements for PIKfyve function, likely related to distinct in vivo needs for endocytic flux. ..