A Garg

Summary

Affiliation: University of Texas Southwestern Medical Center
Country: USA

Publications

  1. ncbi request reprint Adipose tissue distribution pattern in patients with familial partial lipodystrophy (Dunnigan variety)
    A Garg
    Department of Internal Medicine, Center for Human Nutrition, The University of Texas Southwestern Medical Center at Dallas, 75235 9052, USA
    J Clin Endocrinol Metab 84:170-4. 1999
  2. ncbi request reprint A gene for congenital generalized lipodystrophy maps to human chromosome 9q34
    A Garg
    Department of Internal Medicine, and Center for Human Nutrition, University of Texas Southwestern Medical Center at Dallas, 75235, USA
    J Clin Endocrinol Metab 84:3390-4. 1999
  3. ncbi request reprint Skeletal muscle morphology and exercise response in congenital generalized lipodystrophy
    A Garg
    Department of Internal Medicine, The Center for Human Nutrition, University of Texas Southwestern Medical Center, Dallas 75390 9052, USA
    Diabetes Care 23:1545-50. 2000
  4. ncbi request reprint Gender differences in the prevalence of metabolic complications in familial partial lipodystrophy (Dunnigan variety)
    A Garg
    Department of Internal Medicine and the Center for Human Nutrition, University of Texas Southwestern Medical Center, Dallas 75235 9052, USA
    J Clin Endocrinol Metab 85:1776-82. 2000
  5. pmc Homozygous null mutations in ZMPSTE24 in restrictive dermopathy: evidence of genetic heterogeneity
    Z Ahmad
    Division of Nutrition and Metabolic Diseases, Department of Internal Medicine, Center for Human Nutrition, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
    Clin Genet 81:158-64. 2012
  6. pmc Overlapping syndrome with familial partial lipodystrophy, Dunnigan variety and cardiomyopathy due to amino-terminal heterozygous missense lamin A/C mutations
    L Subramanyam
    Department of Internal Medicine, Division of Nutrition and Metabolic Diseases, Center for Human Nutrition, University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390 8537, USA
    Clin Genet 78:66-73. 2010
  7. ncbi request reprint Physico-chemical properties of low density lipoproteins in normolipidemic Asian Indian men
    N Abate
    Center for Human Nutrition, University of Texas Southwestern Medical Center at Dallas, USA
    Horm Metab Res 27:326-31. 1995
  8. ncbi request reprint Severe islet amyloidosis in congenital generalized lipodystrophy
    A Garg
    Department of Internal Medicine, University of Texas Southwestern Medical Center at Dallas 75235 9052, USA
    Diabetes Care 19:28-31. 1996
  9. ncbi request reprint Post-mortem findings in familial partial lipodystrophy, Dunnigan variety
    W A Haque
    Department of Internal Medicine, Division of Nutrition and Metabolic Diseases, Center for Human Nutrition, University of Texas Southwestern Medical Center, Dallas, TX 75390 9052, USA
    Diabet Med 19:1022-5. 2002
  10. ncbi request reprint High-monounsaturated-fat diets for patients with diabetes mellitus: a meta-analysis
    A Garg
    Center for Human Nutrition and the Department of Internal Medicine and Clinical Nutrition, University of Texas Southwestern Medical Center, and Department of Veterans Affairs Medical Center, Dallas 75235 9052, USA
    Am J Clin Nutr 67:577S-582S. 1998

Collaborators

  • R Wilson
  • N Abate
  • M Shah
  • S B Patel
  • E Arioglu
  • S O'Rahilly
  • ANNE MARY BOWCOCK
  • A K Agarwal
  • Z Ahmad
  • L Subramanyam
  • Y Miyoshi
  • S K Nair
  • W A Haque
  • E Arch
  • J Glass
  • S R Phadke
  • R A Speckman
  • V Simha
  • M Taniike
  • N Namba
  • I Mohri
  • M Akagi
  • S Mushiake
  • M Shima
  • R J Auchus
  • K Ozono
  • K Kato-Nishimura
  • M Yamagata
  • S Nakajima
  • B M Prasanna
  • N N Singh
  • R S Rathore
  • T A S Setty
  • R I Barnes
  • F Vuitch
  • S I Taylor
  • L Bennett
  • M Lovett
  • F Du
  • R Veile

Detail Information

Publications16

  1. ncbi request reprint Adipose tissue distribution pattern in patients with familial partial lipodystrophy (Dunnigan variety)
    A Garg
    Department of Internal Medicine, Center for Human Nutrition, The University of Texas Southwestern Medical Center at Dallas, 75235 9052, USA
    J Clin Endocrinol Metab 84:170-4. 1999
    ..The pattern of fat distribution in the male and females was similar. We conclude that FPLD results in a characteristic absence of sc fat from the extremities, with preservation of intermuscular fat stores...
  2. ncbi request reprint A gene for congenital generalized lipodystrophy maps to human chromosome 9q34
    A Garg
    Department of Internal Medicine, and Center for Human Nutrition, University of Texas Southwestern Medical Center at Dallas, 75235, USA
    J Clin Endocrinol Metab 84:3390-4. 1999
    ..Identification of the CGL gene(s) will contribute to our understanding of the adipocyte differentiation and elucidation of the mechanisms of insulin resistance in disorders of adipose tissue...
  3. ncbi request reprint Skeletal muscle morphology and exercise response in congenital generalized lipodystrophy
    A Garg
    Department of Internal Medicine, The Center for Human Nutrition, University of Texas Southwestern Medical Center, Dallas 75390 9052, USA
    Diabetes Care 23:1545-50. 2000
    ..We investigated whether insulin resistance in CGL patients is associated with abnormal muscle morphology and whether increased muscularity imparts increased muscle strength and exercise capacity..
  4. ncbi request reprint Gender differences in the prevalence of metabolic complications in familial partial lipodystrophy (Dunnigan variety)
    A Garg
    Department of Internal Medicine and the Center for Human Nutrition, University of Texas Southwestern Medical Center, Dallas 75235 9052, USA
    J Clin Endocrinol Metab 85:1776-82. 2000
    ..These observations raise the possibility that women with generalized and regional obesity may also have more severe metabolic sequelae of insulin resistance...
  5. pmc Homozygous null mutations in ZMPSTE24 in restrictive dermopathy: evidence of genetic heterogeneity
    Z Ahmad
    Division of Nutrition and Metabolic Diseases, Department of Internal Medicine, Center for Human Nutrition, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
    Clin Genet 81:158-64. 2012
    ..This report provides evidence of genetic heterogeneity among RD and concludes that there may be an additional locus for RD which remains to be identified...
  6. pmc Overlapping syndrome with familial partial lipodystrophy, Dunnigan variety and cardiomyopathy due to amino-terminal heterozygous missense lamin A/C mutations
    L Subramanyam
    Department of Internal Medicine, Division of Nutrition and Metabolic Diseases, Center for Human Nutrition, University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390 8537, USA
    Clin Genet 78:66-73. 2010
    ..Furthermore, the underlying molecular mechanisms by which these amino-terminal mutations cause lipodystrophy as well as cardiomyopathy remain to be understood...
  7. ncbi request reprint Physico-chemical properties of low density lipoproteins in normolipidemic Asian Indian men
    N Abate
    Center for Human Nutrition, University of Texas Southwestern Medical Center at Dallas, USA
    Horm Metab Res 27:326-31. 1995
    ..Therefore, we exclude a genetic predisposition to atherogenic LDL phenotype as a factor contributing to the high incidence of coronary heart disease in migrant Asian Indians...
  8. ncbi request reprint Severe islet amyloidosis in congenital generalized lipodystrophy
    A Garg
    Department of Internal Medicine, University of Texas Southwestern Medical Center at Dallas 75235 9052, USA
    Diabetes Care 19:28-31. 1996
    ..We studied pancreatic islet pathology in congenital generalized lipodystrophy, a genetic syndrome of extreme insulin resistance that may provide some clues...
  9. ncbi request reprint Post-mortem findings in familial partial lipodystrophy, Dunnigan variety
    W A Haque
    Department of Internal Medicine, Division of Nutrition and Metabolic Diseases, Center for Human Nutrition, University of Texas Southwestern Medical Center, Dallas, TX 75390 9052, USA
    Diabet Med 19:1022-5. 2002
    ..We studied autopsy findings in two patients with FPLD to determine fat distribution and organ involvement...
  10. ncbi request reprint High-monounsaturated-fat diets for patients with diabetes mellitus: a meta-analysis
    A Garg
    Center for Human Nutrition and the Department of Internal Medicine and Clinical Nutrition, University of Texas Southwestern Medical Center, and Department of Veterans Affairs Medical Center, Dallas 75235 9052, USA
    Am J Clin Nutr 67:577S-582S. 1998
    ..Therefore, a diet rich in cis-monounsaturated fat can be advantageous for both patients with type 1 or type 2 diabetes who are trying to maintain or lose weight...
  11. ncbi request reprint Genetic basis of congenital generalized lipodystrophy
    A K Agarwal
    Division of Nutrition and Metabolic Diseases, Department of Internal Medicine, Center for Human Nutrition, University of Texas Southwestern Medical Center, Dallas, 75390, USA
    Int J Obes Relat Metab Disord 28:336-9. 2004
    ..Thus, several distinct mechanisms can lead to extreme lack of adipose tissue in humans and cause CGL...
  12. ncbi request reprint The role of diet, exercise and smoking in dyslipidaemia in HIV-infected patients with lipodystrophy
    M Shah
    Division of Nutrition and Metabolic Diseases, Department of Internal Medicine and Center for Human Nutrition, University of Texas Southwestern Medical Center at Dallas, Dallas, TX 76129, USA
    HIV Med 6:291-8. 2005
    ..Lipodystrophy in HIV-infected (LDHIV) patients receiving protease inhibitors (PIs) is associated with dyslipidaemia. Whether lifestyle factors play a role in dyslipidaemia in LDHIV subjects on PIs is not well characterized...
  13. ncbi request reprint Phenotypic heterogeneity in patients with familial partial lipodystrophy (dunnigan variety) related to the site of missense mutations in lamin a/c gene
    A Garg
    Center for Human Nutrition, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA
    J Clin Endocrinol Metab 86:59-65. 2001
    ..Therefore, a unique phenotype of atypical FPLD may result from disrupted interaction of lamin A with other proteins and chromatin compared with typical FPLD, in which interaction of both lamins A and C may be disrupted...
  14. pmc Mutational and haplotype analyses of families with familial partial lipodystrophy (Dunnigan variety) reveal recurrent missense mutations in the globular C-terminal domain of lamin A/C
    R A Speckman
    Division of Human Genetics, Departments of Genetics and Pediatrics, Washington University School of Medicine, St Louis, MO, USA
    Am J Hum Genet 66:1192-8. 2000
    ..The FPLD mutations R482Q and R482W occurred on different haplotypes, indicating that they are likely to have arisen more than once...
  15. ncbi request reprint Identification and validation of QTLs conferring resistance to sorghum downy mildew (Peronosclerospora sorghi) and Rajasthan downy mildew (P. heteropogoni) in maize
    S K Nair
    Maize Genetics Unit, Indian Agricultural Research Institute, New Delhi, 110012, India
    Theor Appl Genet 110:1384-92. 2005
    ..The QTL information generated in this study provide information that will aid in undertaking an integrated breeding strategy for the transfer of resistance to SDM and RDM in maize lines using marker-assisted selection...
  16. pmc Severe mandibuloacral dysplasia caused by novel compound heterozygous ZMPSTE24 mutations in two Japanese siblings
    Y Miyoshi
    Department of Pediatrics, Osaka University Graduate School of Medicine, Suita, Osaka, Japan
    Clin Genet 73:535-44. 2008
    ..We conclude that ZMPSTE24 deficiency results in accumulation of farnesylated prelamin A, which may be responsible for cellular toxicity and the MAD phenotype...