D M Gardiner

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi The molecular basis of amphibian limb regeneration: integrating the old with the new
    David M Gardiner
    Department of Developmental and Cell Biology, Developmental Biology Center, University of California Irvine, Irvine, CA 92697, USA
    Semin Cell Dev Biol 13:345-52. 2002
  2. ncbi Vertebrate limb regeneration and the origin of limb stem cells
    Susan V Bryant
    Developmental Biology Center and Department of Developmental and Cell Biology, University of California, Irvine 92697-2275, USA
    Int J Dev Biol 46:887-96. 2002
  3. ncbi A stepwise model system for limb regeneration
    Tetsuya Endo
    Department of Developmental and Cell Biology and the Developmental Biology Center, University of California-Irvine, Irvine, CA 92697, USA
    Dev Biol 270:135-45. 2004
  4. ncbi Ontogenetic decline of regenerative ability and the stimulation of human regeneration
    David M Gardiner
    Department of Developmental and Cell Biology and the Developmental Biology Center, University of California, Irvine, California 92697, USA
    Rejuvenation Res 8:141-53. 2005
  5. ncbi Analysis of the expression and function of Wnt-5a and Wnt-5b in developing and regenerating axolotl (Ambystoma mexicanum) limbs
    Sukla Ghosh
    Developmental Biology Center and Department of Developmental and Cell Biology, University of California at Irvine, California 92697, USA
    Dev Growth Differ 50:289-97. 2008
  6. ncbi From biomedicine to natural history research: EST resources for ambystomatid salamanders
    Srikrishna Putta
    Department of Biology, University of Kentucky, Lexington, KY 40506, USA
    BMC Genomics 5:54. 2004
  7. ncbi Genic regions of a large salamander genome contain long introns and novel genes
    Jeramiah J Smith
    Department of Biology and Spinal Cord and Brain Injury Research Center, University of Kentucky, Lexington, KY 40506, USA
    BMC Genomics 10:19. 2009
  8. ncbi Microarray and cDNA sequence analysis of transcription during nerve-dependent limb regeneration
    James R Monaghan
    Department of Biology and Spinal Cord and Brain Injury Research Center, University of Kentucky, Lexington, KY 40506, USA
    BMC Biol 7:1. 2009
  9. ncbi Molecular mechanisms in the control of limb regeneration: the role of homeobox genes
    D M Gardiner
    Department of Developmental and Cell Biology, University of California Irvine 92697, USA
    Int J Dev Biol 40:797-805. 1996
  10. ncbi Environmentally induced limb malformations in mink frogs (Rana septentrionalis)
    D M Gardiner
    Developmental Biology Center, University of California Irvine 92697, USA
    J Exp Zool 284:207-16. 1999

Collaborators

Detail Information

Publications18

  1. ncbi The molecular basis of amphibian limb regeneration: integrating the old with the new
    David M Gardiner
    Department of Developmental and Cell Biology, Developmental Biology Center, University of California Irvine, Irvine, CA 92697, USA
    Semin Cell Dev Biol 13:345-52. 2002
    ....
  2. ncbi Vertebrate limb regeneration and the origin of limb stem cells
    Susan V Bryant
    Developmental Biology Center and Department of Developmental and Cell Biology, University of California, Irvine 92697-2275, USA
    Int J Dev Biol 46:887-96. 2002
    ..Advances in regeneration research will then feed back in terms of devising new strategies for therapies to induce regeneration in organisms such as humans that have traditionally been viewed as incapable of regeneration...
  3. ncbi A stepwise model system for limb regeneration
    Tetsuya Endo
    Department of Developmental and Cell Biology and the Developmental Biology Center, University of California-Irvine, Irvine, CA 92697, USA
    Dev Biol 270:135-45. 2004
    ..Hence, this novel and convenient stepwise model allows for the discovery of necessary and sufficient signals and conditions that control blastema formation, growth, and pattern formation during limb regeneration...
  4. ncbi Ontogenetic decline of regenerative ability and the stimulation of human regeneration
    David M Gardiner
    Department of Developmental and Cell Biology and the Developmental Biology Center, University of California, Irvine, California 92697, USA
    Rejuvenation Res 8:141-53. 2005
    ..Therefore, the challenge for inducing limb regeneration in humans is to discover how to induce fibroblast dedifferentiation...
  5. ncbi Analysis of the expression and function of Wnt-5a and Wnt-5b in developing and regenerating axolotl (Ambystoma mexicanum) limbs
    Sukla Ghosh
    Developmental Biology Center and Department of Developmental and Cell Biology, University of California at Irvine, California 92697, USA
    Dev Growth Differ 50:289-97. 2008
    ....
  6. ncbi From biomedicine to natural history research: EST resources for ambystomatid salamanders
    Srikrishna Putta
    Department of Biology, University of Kentucky, Lexington, KY 40506, USA
    BMC Genomics 5:54. 2004
    ..We developed ESTs for Mexican axolotl (Ambystoma mexicanum) and Eastern tiger salamander (A. tigrinum tigrinum), species with deep and diverse research histories...
  7. ncbi Genic regions of a large salamander genome contain long introns and novel genes
    Jeramiah J Smith
    Department of Biology and Spinal Cord and Brain Injury Research Center, University of Kentucky, Lexington, KY 40506, USA
    BMC Genomics 10:19. 2009
    ..Sixteen BAC clones from the Mexican axolotl (Ambystoma mexicanum: c-value = 32 x 10(9) bp) were isolated and sequenced to characterize the structure of genic regions...
  8. ncbi Microarray and cDNA sequence analysis of transcription during nerve-dependent limb regeneration
    James R Monaghan
    Department of Biology and Spinal Cord and Brain Injury Research Center, University of Kentucky, Lexington, KY 40506, USA
    BMC Biol 7:1. 2009
    ..Innervated (NR) and denervated (DL) forelimbs of Mexican axolotls were amputated and transcripts were sampled after 0, 5, and 14 days of regeneration...
  9. ncbi Molecular mechanisms in the control of limb regeneration: the role of homeobox genes
    D M Gardiner
    Department of Developmental and Cell Biology, University of California Irvine 92697, USA
    Int J Dev Biol 40:797-805. 1996
    ..Given the recent increase in studies of the molecules involved in regeneration, it is likely that many of the functionally important regeneration genes will be identified and characterized in the near future...
  10. ncbi Environmentally induced limb malformations in mink frogs (Rana septentrionalis)
    D M Gardiner
    Developmental Biology Center, University of California Irvine 92697, USA
    J Exp Zool 284:207-16. 1999
    ....
  11. ncbi Expression of Hoxb13 and Hoxc10 in developing and regenerating Axolotl limbs and tails
    M R Carlson
    Developmental Biology Center, University of California, Irvine, California 92697, USA
    Dev Biol 229:396-406. 2001
    ....
  12. ncbi Regulation of dermal fibroblast dedifferentiation and redifferentiation during wound healing and limb regeneration in the Axolotl
    Akira Satoh
    Department of Developmental and Cell Biology and the Developmental Biology Center, University of California Irvine, Irvine, CA 92697 2305, USA
    Dev Growth Differ 50:743-54. 2008
    ..The nerve appears to have a dual function in regeneration by coordinately regulating dedifferentiation and redifferentiation of dermal fibroblasts...
  13. ncbi Nerve-induced ectopic limb blastemas in the Axolotl are equivalent to amputation-induced blastemas
    Akira Satoh
    Department of Developmental and Cell Biology, Natural Sciences II Division, 4114 Natural Sciences II, University of California Irvine, Irvine, CA 92697 2305, USA
    Dev Biol 312:231-44. 2007
    ..Therefore, the ALM is appropriate for identifying the signaling pathways regulating the early events of tetrapod limb regeneration...
  14. ncbi Neurotrophic regulation of epidermal dedifferentiation during wound healing and limb regeneration in the axolotl (Ambystoma mexicanum)
    A Satoh
    Department of Developmental and Cell Biology, The Developmental Biology Center, University of California Irvine, Irvine, CA 92697 2305, USA
    Dev Biol 319:321-35. 2008
    ..Induction of Sp9 expression is nerve-dependent, and we have identified KGF as an endogenous nerve factor that induces expression of Sp9 in the regeneration epithelium...
  15. ncbi Cyclopamine induces digit loss in regenerating axolotl limbs
    Stephane Roy
    Developmental Biology Center and Department of Developmental Cell Biology, University of California at Irvine, Irvine, California 92697, USA
    J Exp Zool 293:186-90. 2002
    ..Our results further demonstrate that shh signaling and function are conserved during limb regeneration in urodeles as in limb development in other vertebrates...
  16. ncbi Neurotrophic regulation of fibroblast dedifferentiation during limb skeletal regeneration in the axolotl (Ambystoma mexicanum)
    Akira Satoh
    Department of Developmental and Cell Biology, University of California Irvine, Irvine, CA 92697 2305, USA
    Dev Biol 337:444-57. 2010
    ....
  17. ncbi The effects of laser irradiation of cartilage on chondrocyte gene expression and the collagen matrix
    Paul K Holden
    Department of Otolaryngology Head and Neck Surgery, University of California, Irvine, California 92612, USA
    Lasers Surg Med 41:487-91. 2009
    ..The aim of the study was to determine if collagen I and II gene expression occurs within laser irradiated rabbit septal cartilage...
  18. ncbi Regrowing human limbs
    Ken Muneoka
    Department of Cell and Molecular Biology, Tulane University, USA
    Sci Am 298:56-63. 2008