Research Topics
| Apar Kishor GantiSummaryAffiliation: University of Nebraska Medical Center Country: USA Publications
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Detail Information
Publications
Vincristine-laden platelet transfusion for patients with refractory thrombocytopeniaApar Kishor Ganti
Section of Oncology Hematology, Department of Internal Medicine, University of Nebraska Medical Center, Omaha 68198, USA
In Vivo 20:559-63. 2006..The aim of the present study was to assess the efficacy of vincristine-laden platelet transfusion for patients with refractory thrombocytopenia...
Pancytopenia due to iron deficiency worsened by iron infusion: a case reportApar Kishor Ganti
Department of Internal Medicine, Division of Oncology Hematology, University of Nebraska Medical Center, Omaha, NE, USA
J Med Case Reports 1:175. 2007..Much less common is the development of thrombocytopenia following replenishment of iron stores...
Predictive ability of Charlson comorbidity index on outcomes from lung cancerApar Kishor Ganti
Department of Internal Medicine, Division of Oncology Hematology, University of Nebraska Medical Center, Omaha
Am J Clin Oncol 34:593-6. 2011..The Charlson Comorbidity Index (CCI) was developed to help predict mortality from chronic medical conditions. This study was undertaken to evaluate whether CCI is correlated with survival in lung cancer...- Treatment of non-small cell lung cancer in the older patientApar Kishor Ganti
Department of Internal Medicine, Omaha VA Medical Center, Omaha, Nebraska, USA
J Natl Compr Canc Netw 10:230-9. 2012..If an older patient is deemed to be fit, it is reasonable to use the treatment options recommended for younger individuals. This article summarizes the available data on the treatment of non-small cell lung cancer in the older patient... - Follicular lymphoma: expanding therapeutic optionsApar Kishor Ganti
Department of Internal Medicine, University of Nebraska, Omaha, Nebraska, USA
Oncology (Williston Park) 19:213-28; discussion 228, 233-6, 239. 2005..Future directions in the treatment of follicular lymphoma include vaccines, antisense therapy, and proteasome inhibitors... - Lung cancer screeningApar Kishor Ganti
Division of Hematology Oncology, Department of Internal Medicine, University of Nebraska Medical Center, 987680 Nebraska Medical Center, Omaha, Nebraska 68198 7680, USA
Oncologist 11:481-7. 2006..Currently, the decision to screen for lung cancer should involve a careful discussion with the individuals involved about the potential advantages, costs, and drawbacks of the approach... - Hormone replacement therapy is associated with decreased survival in women with lung cancerApar Kishor Ganti
Section of Hematology Oncology, Department of Internal Medicine, University of Nebraska Medical Center, Nebraska Medical Center, Omaha, NE 68198 7680, USA
J Clin Oncol 24:59-63. 2006..Hence, we conducted a retrospective study to examine the impact of HRT on the natural history of lung cancer... - Epidermal growth factor inhibition in solid tumoursApar Kishor Ganti
Division of Oncology Hematology, Department of Internal Medicine, University of Nebraska Medical Center, Omaha, NE 68198 7680, USA
Expert Opin Biol Ther 5:1165-74. 2005..Efficacy data for these agents in various human malignancies is presented. Various other agents that are in the early stages of development at present have also been mentioned... - Outcomes after hematopoietic stem-cell transplantation for hematologic malignancies in patients with or without advance care planningApar Kishor Ganti
University of Nebraska Medical Center, Section of Oncology Hematology, 987680 Nebraska Medical Center, Omaha, NE 68198 7680, USA
J Clin Oncol 25:5643-8. 2007..We conducted this analysis to determine if engagement in ACP among patients who undergo HSCT is associated with adverse outcomes... - Limited-stage small-cell lung cancer: therapeutic optionsApar Kishor Ganti
Department of Internal Medicine, University of Nebraska Medical Center 68198 7680, USA
Oncology (Williston Park) 21:303-12; discussion 312, 315-8, 323. 2007..Newer targeted agents are currently being evaluated in this disease and hold the promise of improving current outcomes seen in patients with early-stage disease... - Hematopoietic stem cell transplantation for Hodgkin's disease in a patient with dysfibrinogenemia and thrombosisApar Kishor Ganti
Department of Internal Medicine, Section of Oncology Hematology, University of Nebraska Medical Center, 987680 Nebraska Medical Center, Omaha, NE 68198 7680, USA
J Thromb Thrombolysis 23:155-8. 2007..Management of patients with dysfibrinogenemia and a thrombotic tendency usually involves long-term anticoagulation... - Epidermal growth factor receptor signaling in nonsmall cell lung cancerApar Kishor Ganti
Department of Internal Medicine, University of Nebraska Medical Center, Omaha, 68198 7680, USA
Cancer Invest 28:515-25. 2010..Although women, nonsmokers, patients with adenocarcinoma and patients with Asian ethnicity seem to have better outcomes with erlotinib, the factors predictive for response to these agents are currently the focus of investigation... - Systemic therapy for disseminated basal cell carcinoma: an uncommon manifestation of a common cancerApar Kishor Ganti
Department of Internal Medicine, Division of Oncology Hematology, University of Nebraska Medical Center, Omaha, USA
Cancer Treat Rev 37:440-3. 2011..g. inhibitors of the hedgehog and the epidermal growth factor receptor pathways) that are currently being investigated in this disease. This review summarizes the available data on the epidemiology and management of disseminated BCC... - Current concepts in the diagnosis and management of small-cell lung cancerApar Kishor Ganti
Department of Internal Medicine, Division of Oncology Hematology, University of Nebraska Medical Center, Omaha, Nebraska 68198 7680, USA
Oncology (Williston Park) 24:1034-9. 2010..While the frontline treatment of SCLC has not changed significantly in the past decade, newer agents that are currently being investigated provide hope for better treatment of relapsed/refractory disease for the future... - Lung cancer management in 2010Apar Kishor Ganti
VA Nebraska Western Iowa Health Care System, Omaha, Nebraska, USA
Oncology (Williston Park) 25:64-73. 2011..This review summarizes important recent clinical advances that could have a significant impact on the future care of patients with lung cancer... - Factors affecting bone marrow toxicity following administration of carboplatin and paclitaxel in patients with non-small cell lung cancerApar Kishor Ganti
Department of Internal Medicine, Nebraska Medical Center, Omaha, NE 68198 7680, USA
Anticancer Res 30:1365-9. 2010..Limited data exist regarding specific factors that affect blood count nadirs following chemotherapy... - Association of positive family history with survival of patients with lung cancerApar Kishor Ganti
Department of Internal Medicine, Division of Oncology Hematology, University of Nebraska Medical Center, Omaha, NE 68198 7680, USA
Lung Cancer 63:136-9. 2009..Risk factors for development of lung cancer include a family history of the disease. The effect of family history on lung cancer outcomes is unknown. A study was conducted to investigate this... - Therapeutic options for elderly patients with advanced non-small cell lung cancerEric J Avery
Department of Internal Medicine, University of Nebraska Medical Center, Omaha, NE 68198 2055, USA
Cancer Treat Rev 35:340-4. 2009..New targeted agents used to treat NSCLC have yet to show sufficient improvement in disease outcomes. This review will discuss the current management of elderly patients with advanced non-small cell lung cancer... - Clinical course of lung cancer in patients with chronic kidney diseasePurvi Patel
Department of Internal Medicine, University of North Dakota, School of Medicine, Fargo, ND 58102, USA
Lung Cancer 43:297-300. 2004..Hence though treatment of lung cancer does need to be individualized in the setting of CKD, it should not dissuade the clinician from treating the malignancy... - Cetuximab in hemodialysis: a case reportIbrahim T Aldoss
Department of Internal Medicine, Creighton University Medical Center, Omaha, Nebraska, USA
Head Neck 31:1647-50. 2009..Concurrent chemoradiation with cetuximab has been approved in definitive treatment of locally advanced head and neck cancer. Although cetuximab is not excreted via the kidneys, its use in patients on hemodialysis has not been reported... - Effect of diabetes mellitus on the epidemiology and outcomes of colon cancerNicole Annette Shonka
Department of Internal Medicine, Section of Oncology and Hematology, University of Nebraska Medical Center, Omaha, NE 68198-7680, USA
Med Oncol 23:515-9. 2006..CONCLUSIONS: DM did not affect either the stage at diagnosis, or outcomes from colon cancer. More males with colon cancer tended to have DM and a larger proportion of patients with DM were >or=70 yr at the time of diagnosis... - Survival in untreated early stage non-small cell lung cancerAmandeep S Chadha
Department of Internal Medicine, University of North Dakota School of Medicine, Fargo, ND 58102, USA
Anticancer Res 25:3517-20. 2005..CONCLUSION: Patients with untreated early stages NSCLC have a very poor prognosis. Alternative therapies that are better tolerated should be investigated in these patients with early stage NSCLC who cannot be offered standard treatment... - Successful hematopoietic stem-cell transplantation in multicentric Castleman disease complicated by POEMS syndromeApar Kishor Ganti
Department of Internal Medicine, Division of Oncology/Hematology, University of Nebraska Medical Center, Omaha, Nebraska 68198-7680, USA
Am J Hematol 79:206-10. 2005..He is currently ambulatory and does not need wheelchair assistance. Hematopoietic stem-cell transplantation may be a treatment option for patients with multicentric Castleman disease and POEMS syndrome... - Predictive value of absent bone marrow iron stores in the clinical diagnosis of iron deficiency anemiaApar Kishor Ganti
Department of Internal Medicine, University of North Dakota School of Medicine, 1919 Elm Street N, Fargo, ND 58102, USA
In Vivo 17:389-92. 2003..The finding of absent stores of iron in the bone marrow needs to be taken in conjunction with other laboratory findings and the clinical scenario while making a diagnosis of IDA, since certain other hematological diseases may co-exist... - Lung cancer in women: role of estrogensSubhankar Chakraborty
Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE 68198 7680, USA
Expert Rev Respir Med 4:509-18. 2010..Laboratory evidence lends credence to the carcinogenic effects of estrogens in lung cancer. This article summarizes the current evidence on their role in lung cancer... - Targeted anti-cancer therapy in the elderlyWilson Gonsalves
Department of Internal Medicine, Creighton University Medical Center, Omaha, NE, United States
Crit Rev Oncol Hematol 78:227-42. 2011..This article reviews the current literature on the efficacy, cost-effectiveness and toxicity of the currently approved targeted agents in the elderly population... - Seliciclib in malignanciesIbrahim T Aldoss
Creighton University Medical Center, Department of Internal Medicine, Omaha, NE, USA
Expert Opin Investig Drugs 18:1957-65. 2009..At present, it is in Phase II trials for non-small cell lung cancer and nasopharyngeal carcinoma... - Angiosarcoma of the small intestine: a possible role for thalidomide?Genise Fraiman
Department of Internal Medicine, Veterans Affairs Medical Center, Fargo, ND 58102, USA
Med Oncol 20:397-402. 2003..At that time he was found to have hepatic metastases. He was started on thalidomide as an experimental measure with no change in the performance status and increasing evidence of necrosis in the metastatic lesion... - Chromosomal anomalies in two coexistent myeloproliferative disordersApar Kishor Ganti
Department of Internal Medicine, University of North Dakota School of Medicine and Health Sciences, Fargo, ND 58102, USA
Cancer Genet Cytogenet 145:172-5. 2003..This also raises an interesting therapeutic consideration of using concomitant imatinib mesylate and hydroxyurea... - Predictive value of clinical features at initial presentation in pancreatic adenocarcinoma: a series of 308 casesApar Kishor Ganti
Department of Internal Medicine, University of North Dakota, School of Medicine, Fargo, ND 58102, USA
Med Oncol 19:233-7. 2002..Pancreatic adenocarcinoma is a disease of the elderly associated with a poorer outcome. Knowledge of possible clinical predictors of survival may lead to better patient counseling regarding prognosis... - Uncommon syndromes and treatment manifestations of malignancy: Case 2. Metastatic non-small-cell lung cancer presenting with leukocytosisApar Kishor Ganti
Department of Internal Medicine, University of North Dakota School of Medicine, USA
J Clin Oncol 21:168-70. 2003 - Apparent heparin resistance in a patient with infective endocarditis secondary to elevated factor VIII levelsRamya Thota
Internal Medicine Resident PGY3, Creighton University, 601 N 30th Street, Omaha, NE 68131, USA
J Thromb Thrombolysis 34:132-4. 2012..We hereby report an unusual case of heparin resistance due to increased factor VIII levels in an elderly male with infective endocarditis... - Pulmonary toxicities from targeted therapies: a reviewNicholas A Barber
Division of Hematology Oncology, Department of Internal Medicine, University of Nebraska Medical Center, Omaha, USA
Target Oncol 6:235-43. 2011..Discerning these pulmonary adverse effects may help in making decisions on diagnostic testing and therapy, particularly for those with pulmonary and cardiovascular co-morbidities... - Myeloproliferative syndromes and the associated risk of coronary artery diseaseApar Kishor Ganti
Department of Internal Medicine, University of North Dakota School of Medicine, 1919 Elm Street N, Fargo, ND 58102, USA
Thromb Res 110:83-6. 2003..However, the relationship between these myeloproliferative syndromes and coronary artery disease (CAD) is unclear... - Targeted therapy for squamous cell carcinoma of the head and neckIbrahim T Aldoss
The Department of Internal Medicine, Creighton University Medical Center, Omaha, NE, USA
J Egypt Natl Canc Inst 21:157-66. 2009..Hence these receptors and their downstream pathways make attractive therapeutic targets. This review discusses targeted therapies currently being evaluated for their role in squamous cell carcinoma of the head and neck... - Treatment options for relapsed small-cell lung cancerHatem A Azim
Department of Medical Oncology, National Cancer Institute, Cairo University, Cairo, Egypt
Anticancer Drugs 18:255-61. 2007..This review focuses on the various current and future options, including cytoxic and targeted agents, for salvage therapy in patients with this disease... - Adjuvant chemotherapy for early-stage non-small cell lung cancer: the past, the present and the futureAnil Potti
Duke Institute for Genome Sciences and Policy, Division of Hematology, Duke University Medical Center, Box 3382, CIEMAS, Durham, NC 27710, USA
Expert Opin Biol Ther 6:709-16. 2006..The role of targeted agents in this setting is being investigated. Gene expression profiling studies should help direct chemotherapy to those who would actually benefit from it, thereby saving others from unnecessary toxicity... - Targeted therapy in advanced non-small cell lung cancer (NSCLC): where do we stand?Hatem A Azim
Department of Medical Oncology, National Cancer Institute, Cairo University, Cairo, Egypt
Cancer Treat Rev 32:630-6. 2006..This review will briefly discuss the important trials using these targeted agents in advanced NSCLC... - HER-2/neu overexpression detected by immunohistochemistry in soft tissue sarcomasHeidi Foster
Department of Medicine, University of North Dakota School of Medicine, Fargo, ND 58102, U.S.A
Am J Clin Oncol 26:188-91. 2003..In addition, there may be a role for Herceptin (trastuzumab) alone, or in combination with conventional therapy, in patients with CS, MHF, and DFS... - Immunohistochemical detection of C-kit (CD117) and vascular endothelial growth factor (VEGF) overexpression in mantle cell lymphomaAnil Potti
Department of Medicine, University of North Dakota School of Medicine and Health Sciences, Fargo, ND 58102, USA
Anticancer Res 22:2899-901. 2002..We evaluated the incidence of c-kit (CD117) and vascular endothelial growth factor (VEGF) overexpression in patients with MCL in an effort to identify possible targets for therapeutic intervention... - Comparison of resource utilization and clinical outcomes between teaching and nonteaching medical servicesAmir A Khaliq
Department of Health Administration and Policy, University of Oklahoma Health Sciences Center, College of Public Health, Oklahoma City, OK 73104, USA
J Hosp Med 2:150-7. 2007..To compare the resource utilization and clinical outcomes of medical care delivered on general internal medicine inpatient services at teaching and nonteaching services at an academic hospital... - Effect of pesticide exposure on HER-2/neu overexpression seen in patients with extensive stage small cell lung carcinomaAnil Potti
Department of Medicine, University of North Dakota School of Medicine, Fargo, North Dakota 58102, USA
Clin Cancer Res 9:4872-6. 2003..The aim of this study was to evaluate the relationship, if any, between pesticide exposure and overexpression of the HER-2/neu oncoprotein in extensive stage small cell lung cancer (ESSCLC)...