Anand K Ganesan

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi Broad spectrum identification of SUMO substrates in melanoma cells
    Anand K Ganesan
    Department of Dermatology, University of California, Irvine, CA 92697 2400, USA
    Proteomics 7:2216-21. 2007
  2. ncbi Genome-wide siRNA-based functional genomics of pigmentation identifies novel genes and pathways that impact melanogenesis in human cells
    Anand K Ganesan
    Department of Dermatology, University of California Irvine, Irvine, California, United States of America
    PLoS Genet 4:e1000298. 2008
  3. ncbi Protein interaction network topology uncovers melanogenesis regulatory network components within functional genomics datasets
    Hsiang Ho
    Department of Biological Chemistry, University of California, Irvine, 92697 1700, USA
    BMC Syst Biol 4:84. 2010
  4. ncbi RhoJ regulates melanoma chemoresistance by suppressing pathways that sense DNA damage
    Hsiang Ho
    Department of Dermatology, University of California at Irvine, Irvine, California 92697, USA
    Cancer Res 72:5516-28. 2012
  5. ncbi WIPI1 coordinates melanogenic gene transcription and melanosome formation via TORC1 inhibition
    Hsiang Ho
    Department of Biological Chemistry, University of California, Irvine, CA 92697 2400, USA
    J Biol Chem 286:12509-23. 2011
  6. ncbi The pleiotropic roles of autophagy regulators in melanogenesis
    Hsiang Ho
    Department of Dermatology and Biological Chemistry, University of California, Irvine, CA, USA
    Pigment Cell Melanoma Res 24:595-604. 2011
  7. ncbi RhoJ modulates melanoma invasion by altering actin cytoskeletal dynamics
    Hsiang Ho
    Department of Medicine, University of California, Irvine, Irvine, CA, USA
    Pigment Cell Melanoma Res 26:218-25. 2013
  8. ncbi 9-cis retinoic acid is the ALDH1A1 product that stimulates melanogenesis
    Elyse K Paterson
    Department of Biological Chemistry, University of California, Irvine, CA 92697 2400, USA
    Exp Dermatol 22:202-9. 2013
  9. ncbi Systems-level cancer gene identification from protein interaction network topology applied to melanogenesis-related functional genomics data
    Tijana Milenkovic
    Department of Computer Science, University of California, Irvine, CA 92697 3435, USA
    J R Soc Interface 7:423-37. 2010

Collaborators

Detail Information

Publications9

  1. ncbi Broad spectrum identification of SUMO substrates in melanoma cells
    Anand K Ganesan
    Department of Dermatology, University of California, Irvine, CA 92697 2400, USA
    Proteomics 7:2216-21. 2007
    ..A proteomic SUMO target analysis in melanoma cells identified proteins involved in cellular signaling, growth control, and neural differentiation...
  2. ncbi Genome-wide siRNA-based functional genomics of pigmentation identifies novel genes and pathways that impact melanogenesis in human cells
    Anand K Ganesan
    Department of Dermatology, University of California Irvine, Irvine, California, United States of America
    PLoS Genet 4:e1000298. 2008
    ....
  3. ncbi Protein interaction network topology uncovers melanogenesis regulatory network components within functional genomics datasets
    Hsiang Ho
    Department of Biological Chemistry, University of California, Irvine, 92697 1700, USA
    BMC Syst Biol 4:84. 2010
    ..We experimentally validate our approach in the context of a recently completed RNAi screen to identify novel regulators of melanogenesis...
  4. ncbi RhoJ regulates melanoma chemoresistance by suppressing pathways that sense DNA damage
    Hsiang Ho
    Department of Dermatology, University of California at Irvine, Irvine, California 92697, USA
    Cancer Res 72:5516-28. 2012
    ..These findings identify DNA damage agents and pharmacologic inhibitors of RhoJ/PAK1 as novel synergistic agents that can be used to treat melanomas that are resistant to conventional chemotherapies...
  5. ncbi WIPI1 coordinates melanogenic gene transcription and melanosome formation via TORC1 inhibition
    Hsiang Ho
    Department of Biological Chemistry, University of California, Irvine, CA 92697 2400, USA
    J Biol Chem 286:12509-23. 2011
    ..Taken together, our studies define a distinct role for WIPI1 and TORC1 signaling in controlling the transcription of melanogenic enzymes and melanosome maturation, a process that is distinct from starvation-induced autophagy...
  6. ncbi The pleiotropic roles of autophagy regulators in melanogenesis
    Hsiang Ho
    Department of Dermatology and Biological Chemistry, University of California, Irvine, CA, USA
    Pigment Cell Melanoma Res 24:595-604. 2011
    ....
  7. ncbi RhoJ modulates melanoma invasion by altering actin cytoskeletal dynamics
    Hsiang Ho
    Department of Medicine, University of California, Irvine, Irvine, CA, USA
    Pigment Cell Melanoma Res 26:218-25. 2013
    ..Taken together, these observations identify RHOJ as a melanoma linchpin determinant that regulates both actin cytoskeletal dynamics and chemoresistance by activating PAK1...
  8. ncbi 9-cis retinoic acid is the ALDH1A1 product that stimulates melanogenesis
    Elyse K Paterson
    Department of Biological Chemistry, University of California, Irvine, CA 92697 2400, USA
    Exp Dermatol 22:202-9. 2013
    ....
  9. ncbi Systems-level cancer gene identification from protein interaction network topology applied to melanogenesis-related functional genomics data
    Tijana Milenkovic
    Department of Computer Science, University of California, Irvine, CA 92697 3435, USA
    J R Soc Interface 7:423-37. 2010
    ..Understanding the underlying principles of this phenomenon is an open question, with a potential for increasing our understanding of complex diseases...