Robin E Gandley

Summary

Affiliation: University of Pittsburgh
Country: USA

Publications

  1. ncbi request reprint Moderate ascorbate deficiency increases myogenic tone of arteries from pregnant but not virgin ascorbate-dependent rats
    Rolando J J Ramirez
    Magee Women Research Institute, Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Pittsburgh, Pittsburgh, PA, USA
    Hypertension 47:454-60. 2006
  2. ncbi request reprint S-nitrosoalbumin-mediated relaxation is enhanced by ascorbate and copper: effects in pregnancy and preeclampsia plasma
    Robin E Gandley
    Magee Womens Research Institute and Department of Environmental and Occupational Health, University of Pittsburgh, 204 Craft Ave, Pittsburgh, PA 15213, USA
    Hypertension 45:21-7. 2005
  3. pmc Low placental growth factor across pregnancy identifies a subset of women with preterm preeclampsia: type 1 versus type 2 preeclampsia?
    Robert W Powers
    Department of Obstetrics, Gynecology, and Reproductive SciencesMagee Womens Research Institute, University of Pittsburgh, Pittsburgh, PA, USA
    Hypertension 60:239-46. 2012
  4. pmc First trimester uric acid and adverse pregnancy outcomes
    S Katherine Laughon
    Department of Obstetrics, Gynecology and Reproductive Services, University of Pittsburgh, Pittsburgh, PA, USA
    Am J Hypertens 24:489-95. 2011
  5. pmc Vascular pool of releasable soluble VEGF receptor-1 (sFLT1) in women with previous preeclampsia and uncomplicated pregnancy
    Tracey L Weissgerber
    Division of Nephrology and Hypertension T L W, Mayo Clinic, Rochester, Minnesota 55905 Beth Israel Deaconess Medical Center A R, Boston, Massachusetts 02215 Magee Womens Research Institute A C M, L R E, R W P, J M R, R E G, C A H, and Department of Obstetrics, Gynecology, and Reproductive Sciences R W P, J M R, C A H, University of Pittsburgh, Pittsburgh, Pennsylvania 15213 Department of Environmental and Occupational Health R E G, C A H, and Department of Epidemiology J M R, Graduate School of Public Health J M R, University of Pittsburgh, Pittsburgh, Pennsylvania 15261 and Clinical and Translational Science Institute J M R, University of Pittsburgh, Pittsburgh, Pennsylvania 15260
    J Clin Endocrinol Metab 99:978-87. 2014
  6. pmc Early hypercholesterolemia contributes to vasomotor dysfunction and injury associated atherogenesis that can be inhibited by nitric oxide
    Kathleen G Raman
    Division of Vascular Surgery, Department of Surgery, University of Pittsburgh, Pittsburgh, PA 15213, USA
    J Vasc Surg 53:754-63. 2011
  7. pmc Haptoglobin phenotype, angiogenic factors, and preeclampsia risk
    Tracey L Weissgerber
    Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Pittsburgh, Pittsburgh, PA, USA
    Am J Obstet Gynecol 206:358.e10-8. 2012
  8. pmc Cigarette exposure induces changes in maternal vascular function in a pregnant mouse model
    Robin E Gandley
    Magee Womens Research Institute, 204 Craft Ave, Pittsburgh, PA 15213, USA
    Am J Physiol Regul Integr Comp Physiol 298:R1249-56. 2010
  9. pmc Increased myeloperoxidase in the placenta and circulation of women with preeclampsia
    Robin E Gandley
    Magee Womens Research Institute, 204 Craft Ave, Pittsburgh, PA 15213, USA
    Hypertension 52:387-93. 2008
  10. ncbi request reprint Moderate hyperhomocysteinemia decreases endothelial-dependent vasorelaxation in pregnant but not nonpregnant mice
    Robert W Powers
    Magee Women s Research Institute and Department of Obstetrics and Gynecology and Reproductive Sciences, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213
    Hypertension 44:327-33. 2004

Collaborators

Detail Information

Publications12

  1. ncbi request reprint Moderate ascorbate deficiency increases myogenic tone of arteries from pregnant but not virgin ascorbate-dependent rats
    Rolando J J Ramirez
    Magee Women Research Institute, Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Pittsburgh, Pittsburgh, PA, USA
    Hypertension 47:454-60. 2006
    ..This increase may result from a decrease in nitric oxide-mediated modulation of the myogenic contractile response...
  2. ncbi request reprint S-nitrosoalbumin-mediated relaxation is enhanced by ascorbate and copper: effects in pregnancy and preeclampsia plasma
    Robin E Gandley
    Magee Womens Research Institute and Department of Environmental and Occupational Health, University of Pittsburgh, 204 Craft Ave, Pittsburgh, PA 15213, USA
    Hypertension 45:21-7. 2005
    ..We suggest that the higher circulating levels of SNO-Alb, in women with preeclampsia, reflect a deficiency in Asc/Cu-mediated release of NO from SNO-Alb...
  3. pmc Low placental growth factor across pregnancy identifies a subset of women with preterm preeclampsia: type 1 versus type 2 preeclampsia?
    Robert W Powers
    Department of Obstetrics, Gynecology, and Reproductive SciencesMagee Womens Research Institute, University of Pittsburgh, Pittsburgh, PA, USA
    Hypertension 60:239-46. 2012
    ..Identifying women with consistently low plasma PGF during pregnancy may provide a greater understanding of preeclampsia pathophysiology and may provide more focused research and clinical activities...
  4. pmc First trimester uric acid and adverse pregnancy outcomes
    S Katherine Laughon
    Department of Obstetrics, Gynecology and Reproductive Services, University of Pittsburgh, Pittsburgh, PA, USA
    Am J Hypertens 24:489-95. 2011
    ....
  5. pmc Vascular pool of releasable soluble VEGF receptor-1 (sFLT1) in women with previous preeclampsia and uncomplicated pregnancy
    Tracey L Weissgerber
    Division of Nephrology and Hypertension T L W, Mayo Clinic, Rochester, Minnesota 55905 Beth Israel Deaconess Medical Center A R, Boston, Massachusetts 02215 Magee Womens Research Institute A C M, L R E, R W P, J M R, R E G, C A H, and Department of Obstetrics, Gynecology, and Reproductive Sciences R W P, J M R, C A H, University of Pittsburgh, Pittsburgh, Pennsylvania 15213 Department of Environmental and Occupational Health R E G, C A H, and Department of Epidemiology J M R, Graduate School of Public Health J M R, University of Pittsburgh, Pittsburgh, Pennsylvania 15261 and Clinical and Translational Science Institute J M R, University of Pittsburgh, Pittsburgh, Pennsylvania 15260
    J Clin Endocrinol Metab 99:978-87. 2014
    ..Research examining the source of excess soluble fms-like tyrosine kinase 1 (sFLT1) in preeclampsia has focused on the placenta. The potential contribution of the releasable store of sFLT1 in the systemic vasculature is unknown...
  6. pmc Early hypercholesterolemia contributes to vasomotor dysfunction and injury associated atherogenesis that can be inhibited by nitric oxide
    Kathleen G Raman
    Division of Vascular Surgery, Department of Surgery, University of Pittsburgh, Pittsburgh, PA 15213, USA
    J Vasc Surg 53:754-63. 2011
    ..The efficacy of NO therapy to protect against the injury response in this setting was also assessed...
  7. pmc Haptoglobin phenotype, angiogenic factors, and preeclampsia risk
    Tracey L Weissgerber
    Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Pittsburgh, Pittsburgh, PA, USA
    Am J Obstet Gynecol 206:358.e10-8. 2012
    ..We sought to determine whether haptoglobin (Hp) phenotype is related to preeclampsia risk, or to plasma concentrations of soluble endoglin (sEng), soluble fms-like tyrosine kinase 1 (sFlt-1), and placental growth factor (PlGF)...
  8. pmc Cigarette exposure induces changes in maternal vascular function in a pregnant mouse model
    Robin E Gandley
    Magee Womens Research Institute, 204 Craft Ave, Pittsburgh, PA 15213, USA
    Am J Physiol Regul Integr Comp Physiol 298:R1249-56. 2010
    ..Functional maternal vascular perturbations during pregnancy, specifically impaired peripheral and uterine vasodilation, may contribute to a mechanism by which smoking results in fetal growth restriction...
  9. pmc Increased myeloperoxidase in the placenta and circulation of women with preeclampsia
    Robin E Gandley
    Magee Womens Research Institute, 204 Craft Ave, Pittsburgh, PA 15213, USA
    Hypertension 52:387-93. 2008
    ..We speculate that MPO may contribute to the oxidative damage reported in the endothelium and placenta of women with preeclampsia...
  10. ncbi request reprint Moderate hyperhomocysteinemia decreases endothelial-dependent vasorelaxation in pregnant but not nonpregnant mice
    Robert W Powers
    Magee Women s Research Institute and Department of Obstetrics and Gynecology and Reproductive Sciences, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213
    Hypertension 44:327-33. 2004
    ..This effect appears to result from a loss in NO-mediated relaxation that may be mediated by the oxidative inactivation of the NO synthase cofactor tetrahydrobiopterin...
  11. pmc Elevated first-trimester uric acid concentrations are associated with the development of gestational diabetes
    S Katherine Laughon
    Department of Obstetrics, Gynecology and Reproductive Services, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    Am J Obstet Gynecol 201:402.e1-5. 2009
    ..We sought to demonstrate that elevated first-trimester uric acid is associated with development of gestational diabetes mellitus (GDM)...
  12. ncbi request reprint Myogenic reactivity is reduced in small renal arteries isolated from relaxin-treated rats
    Jacqueline Novak
    Department of Obstetrics, University of Pittsburgh School of Medicine and Magee Womens Research Institute, Pennsylvania 15213, USA
    Am J Physiol Regul Integr Comp Physiol 283:R349-55. 2002
    ..Thus relaxin administration to nonpregnant rats mimics pregnancy, insofar as myogenic reactivity of small renal and mesenteric arteries is reduced in both conditions...