Chandrashekhar R Gandhi

Summary

Affiliation: University of Pittsburgh
Country: USA

Publications

  1. request reprint
    Gandhi C, Kuddus R, Nemoto E, Murase N. Endotoxin treatment causes an upregulation of the endothelin system in the liver: amelioration of increased portal resistance by endothelin receptor antagonism. J Gastroenterol Hepatol. 2001;16:61-9 pubmed
    ..These results suggest that the upregulated hepatic ET-1 system is an important mechanism of increased portal resistance and related complications of endotoxemia. ..
  2. Gandhi C, Murase N, Starzl T. Cholera toxin-sensitive GTP-binding protein-coupled activation of augmenter of liver regeneration (ALR) receptor and its function in rat kupffer cells. J Cell Physiol. 2010;222:365-73 pubmed publisher
    ..These results demonstrate specific G-protein coupled binding of ALR and its function in Kupffer cells and suggest that mediators produced by ALR-stimulated Kupffer cells may elicit physiologically important effects on hepatocytes. ..

Locale

Detail Information

Publications2

  1. request reprint
    Gandhi C, Kuddus R, Nemoto E, Murase N. Endotoxin treatment causes an upregulation of the endothelin system in the liver: amelioration of increased portal resistance by endothelin receptor antagonism. J Gastroenterol Hepatol. 2001;16:61-9 pubmed
    ..These results suggest that the upregulated hepatic ET-1 system is an important mechanism of increased portal resistance and related complications of endotoxemia. ..
  2. Gandhi C, Murase N, Starzl T. Cholera toxin-sensitive GTP-binding protein-coupled activation of augmenter of liver regeneration (ALR) receptor and its function in rat kupffer cells. J Cell Physiol. 2010;222:365-73 pubmed publisher
    ..These results demonstrate specific G-protein coupled binding of ALR and its function in Kupffer cells and suggest that mediators produced by ALR-stimulated Kupffer cells may elicit physiologically important effects on hepatocytes. ..