Alison P Galvani

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc The maintenance of sex in parasites
    Alison P Galvani
    Department of Integrative Biology, University of California, Berkeley, CA 94720 3140, USA
    Proc Biol Sci 270:19-28. 2003
  2. ncbi request reprint Immunity, antigenic heterogeneity, and aggregation of helminth parasites
    Alison P Galvani
    Department of Integrative Biology, University of California, Berkeley, California 94720, USA
    J Parasitol 89:232-41. 2003
  3. pmc Intense selection in an age-structured population
    Alison P Galvani
    Department of Integrative Biology, University of California, Berkeley, CA 94720, USA
    Proc Biol Sci 271:171-6. 2004
  4. pmc Severe acute respiratory syndrome: temporal stability and geographic variation in case-fatality rates and doubling times
    Alison P Galvani
    University of California, Berkeley, California, USA
    Emerg Infect Dis 9:991-4. 2003
  5. pmc Evaluating plague and smallpox as historical selective pressures for the CCR5-Delta 32 HIV-resistance allele
    Alison P Galvani
    Department of Integrative Biology, University of California, Berkeley, CA 94720, USA
    Proc Natl Acad Sci U S A 100:15276-9. 2003
  6. pmc The geographic spread of the CCR5 Delta32 HIV-resistance allele
    John Novembre
    Department of Integrative Biology, University of California, Berkeley, California, United States of America
    PLoS Biol 3:e339. 2005
  7. pmc Emerging infections: what have we learned from SARS?
    Alison P Galvani
    University of California, Berkeley, USA
    Emerg Infect Dis 10:1351-2. 2004
  8. pmc Curtailing transmission of severe acute respiratory syndrome within a community and its hospital
    James O Lloyd-Smith
    Biophysics Graduate Group, University of California, Berkeley, CA 94720, USA
    Proc Biol Sci 270:1979-89. 2003
  9. ncbi request reprint Age-dependent epidemiological patterns and strain diversity in helminth parasites
    Alison P Galvani
    Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    J Parasitol 91:24-30. 2005
  10. ncbi request reprint Optimal timing of disease transmission in an age-structured population
    Timothy C Reluga
    Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, CT 06520, USA
    Bull Math Biol 69:2711-22. 2007

Detail Information

Publications26

  1. pmc The maintenance of sex in parasites
    Alison P Galvani
    Department of Integrative Biology, University of California, Berkeley, CA 94720 3140, USA
    Proc Biol Sci 270:19-28. 2003
    ..We suggest that the enhancement of strain diversity, despite stochastic extinction of strains, may be critical to the evolutionary success of sex in long-lived parasites...
  2. ncbi request reprint Immunity, antigenic heterogeneity, and aggregation of helminth parasites
    Alison P Galvani
    Department of Integrative Biology, University of California, Berkeley, California 94720, USA
    J Parasitol 89:232-41. 2003
    ....
  3. pmc Intense selection in an age-structured population
    Alison P Galvani
    Department of Integrative Biology, University of California, Berkeley, CA 94720, USA
    Proc Biol Sci 271:171-6. 2004
    ..We relate our model and results to selection for disease resistance, although the results have broader implications for inferences about past selection pressures in general...
  4. pmc Severe acute respiratory syndrome: temporal stability and geographic variation in case-fatality rates and doubling times
    Alison P Galvani
    University of California, Berkeley, California, USA
    Emerg Infect Dis 9:991-4. 2003
    ..Factors that may alter future estimates of case-fatality rates, reasons for heterogeneity in doubling times among countries, and implications for the control of SARS are discussed...
  5. pmc Evaluating plague and smallpox as historical selective pressures for the CCR5-Delta 32 HIV-resistance allele
    Alison P Galvani
    Department of Integrative Biology, University of California, Berkeley, CA 94720, USA
    Proc Natl Acad Sci U S A 100:15276-9. 2003
    ..By using a population genetic framework that takes into account the temporal pattern and age-dependent nature of specific diseases, we find that smallpox is more consistent with this historical role...
  6. pmc The geographic spread of the CCR5 Delta32 HIV-resistance allele
    John Novembre
    Department of Integrative Biology, University of California, Berkeley, California, United States of America
    PLoS Biol 3:e339. 2005
    ..Our results describe the evolutionary history of the Delta32 allele and establish a general methodology for studying the geographic distribution of selected alleles...
  7. pmc Emerging infections: what have we learned from SARS?
    Alison P Galvani
    University of California, Berkeley, USA
    Emerg Infect Dis 10:1351-2. 2004
  8. pmc Curtailing transmission of severe acute respiratory syndrome within a community and its hospital
    James O Lloyd-Smith
    Biophysics Graduate Group, University of California, Berkeley, CA 94720, USA
    Proc Biol Sci 270:1979-89. 2003
    ..The implications of our results for future emerging pathogens are discussed...
  9. ncbi request reprint Age-dependent epidemiological patterns and strain diversity in helminth parasites
    Alison P Galvani
    Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    J Parasitol 91:24-30. 2005
    ..If this hypothesis is correct, estimates of epidemiological parameters from field data and the potential for control of helminth diseases might require reevaluation...
  10. ncbi request reprint Optimal timing of disease transmission in an age-structured population
    Timothy C Reluga
    Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, CT 06520, USA
    Bull Math Biol 69:2711-22. 2007
    ..This provides a rigorous justification of the concept of "endemic stability," and demonstrates that folk-practices may have been historically justified...
  11. pmc Vaccinating in disease-free regions: a vaccine model with application to yellow fever
    Cláudia T Codeço
    Programa de Computacao Cientifica, Fundacao Oswaldo Cruz, Avenida Brasil, 4365, Rio de Janeiro, RJ, Brazil
    J R Soc Interface 4:1119-25. 2007
    ..In summary, our model highlights the nonlinear dependence of an individual's best strategy on the preparedness of a response to a yellow fever outbreak or other emergent infectious disease...
  12. pmc Prevention of nosocomial transmission of extensively drug-resistant tuberculosis in rural South African district hospitals: an epidemiological modelling study
    Sanjay Basu
    Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, CT 06520, USA
    Lancet 370:1500-7. 2007
    ..We modelled the plausible effect of rapidly available infection control strategies on the overall course of the XDR tuberculosis epidemic in a rural area of South Africa...
  13. ncbi request reprint Extensively drug-resistant tuberculosis in South Africa
    Sanjay Basu
    Lancet 369:272-3. 2007
  14. pmc Modeling targeted ivermectin treatment for controlling river blindness
    Eric M Poolman
    Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Connecticut 06520 8034, USA
    Am J Trop Med Hyg 75:921-7. 2006
    ..Targeted allocation therefore poses significantly lower risk of adverse effects, while potentially delaying the emergence and spread of ivermectin resistance, relative to untargeted allocation...
  15. ncbi request reprint Evolving public perceptions and stability in vaccine uptake
    Timothy C Reluga
    Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, CT 06520, USA
    Math Biosci 204:185-98. 2006
    ..This research illustrates the importance of applying temporal models to an inherently temporal situation, namely, the time evolution of vaccine coverage in an informed population with a voluntary vaccination policy...
  16. pmc Evaluating candidate agents of selective pressure for cystic fibrosis
    Eric M Poolman
    Department of Epidemiology and Public Health, Yale University School of Medicine, 60 College Street, Room 147, New Haven, CT 06520, USA
    J R Soc Interface 4:91-8. 2007
    ..Implications for the future trajectory of cystic fibrosis are discussed. Our result supports the importance of novel investigations into the role of arylsulphatase B deficiency in cystic fibrosis and tuberculosis...
  17. ncbi request reprint The ethics of influenza vaccination
    Alison P Galvani
    Science 313:758-60; author reply 758-60. 2006
  18. ncbi request reprint A model of spatial epidemic spread when individuals move within overlapping home ranges
    Timothy C Reluga
    Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, CT 06520, USA
    Bull Math Biol 68:401-16. 2006
    ..We also calculate approximate upper bounds for the rates of an epidemic's spatial spread. Guidelines are suggested for determining which limit is most appropriate for a specific disease...
  19. ncbi request reprint Epidemiology: dimensions of superspreading
    Alison P Galvani
    Nature 438:293-5. 2005
  20. ncbi request reprint Dynamically modeling SARS and other newly emerging respiratory illnesses: past, present, and future
    Chris T Bauch
    Department of Mathematics and Statistics, University of Guelph, Guelph, Ontario, Canada
    Epidemiology 16:791-801. 2005
    ....
  21. ncbi request reprint Ecological and immunological determinants of influenza evolution
    Neil M Ferguson
    Department of Infectious Disease Epidemiology, Faculty of Medicine, Imperial College London, St Mary s Campus, Norfolk Place, London W2 1PG, UK
    Nature 422:428-33. 2003
    ....
  22. pmc The role of mutation accumulation in HIV progression
    Alison P Galvani
    Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, CT 06520, USA
    Proc Biol Sci 272:1851-8. 2005
    ..Mutation accumulation may explain not only the decline in CD4+T cells, but also the functional deterioration of CD4+T cells, CD8+T cells and B cells, and the exhaustion of lymphocyte regeneration...
  23. ncbi request reprint The evolutionary history of the CCR5-Delta32 HIV-resistance mutation
    Alison P Galvani
    Department of Epidemiology and Public Health, Yale School of Medicine, New Haven, CT 06520, USA
    Microbes Infect 7:302-9. 2005
    ..We also discuss parallel evolution that has occurred at the CCR5 locus of other primate species. Finally, we highlight the promise that therapies based on interfering with the CCR5 receptor could have in the treatment of HIV...
  24. ncbi request reprint The effect of treatment on pathogen virulence
    Travis C Porco
    San Francisco Department of Public Health, 101 Grove St, Suite 204, San Francisco, CA, USA
    J Theor Biol 233:91-102. 2005
    ..Thus we show that conflict can arise between the epidemiological benefits of treatment and the evolutionary risks of heightened virulence...
  25. ncbi request reprint Using network models to approximate spatial point-process models
    Chris T Bauch
    Department of Mathematics and Statistics, McMaster University, Hamilton, Ont, Canada L8S 4K1
    Math Biosci 184:101-14. 2003
    ..Insofar as point-process models are accurate representations of real spatial biological systems, our example also supports the view that network models are realistic representations of space...
  26. ncbi request reprint Vaccination and the evolutionary ecology of human papillomavirus
    Eric M Poolman
    Department of Epidemiology and Public Health, Yale University School of Medicine, 60 College Street, New Haven, CT 06520 8034, USA
    Vaccine 26:C25-30. 2008
    ..If natural infection provides greater cross-immunity than vaccination, vaccination may expand available niche space up to 470-fold. The balance of epidemiologic data suggests vaccination will reduce the available niche space...