Amelia Gallitano Mendel
Affiliation: University of Arizona
Gallitano Mendel A, Wozniak D, Pehek E, Milbrandt J. Mice lacking the immediate early gene Egr3 respond to the anti-aggressive effects of clozapine yet are relatively resistant to its sedating effects. Neuropsychopharmacology. 2008;33:1266-75 pubmed
..This suggests the possibility that Egr3-/- mice may provide insight into the neurobiological abnormalities underlying schizophrenia. ..
Gallitano Mendel A, Izumi Y, Tokuda K, Zorumski C, Howell M, Muglia L, et al
. The immediate early gene early growth response gene 3 mediates adaptation to stress and novelty. Neuroscience. 2007;148:633-43 pubmed
..These findings are the first demonstration of the requirement for an IEG-TF in mediating the response to stress and novelty, and in the establishment of LTD. ..
Gallitano A, Tillman R, Dinu V, Geller B. Family-based association study of early growth response gene 3 with child bipolar I disorder. J Affect Disord. 2012;138:387-96 pubmed publisher
..Such studies may help reveal mechanisms by which environment can interact with genetic predisposition to influence this severe mental illness. ..
Hastings K, Elizalde D, Muppana L, LeVine S, Kamel C, Ingram W, et al
. Nab2 maintains thymus cellularity with aging and stress. Mol Immunol. 2017;85:185-195 pubmed publisher
..These findings indicate a requirement for Nab2 in maintaining thymocyte number in male mice with age and in response to stress. ..