Zoran Galic

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Generation of T lineage cells from human embryonic stem cells in a feeder free system
    Zoran Galic
    Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, 90095, USA
    Stem Cells 27:100-7. 2009
  2. doi request reprint Derivation of primordial germ cells from human embryonic and induced pluripotent stem cells is significantly improved by coculture with human fetal gonadal cells
    Tae Sub Park
    Department of Molecular Cell and Developmental Biology, University of California, Los Angeles, CA, USA
    Stem Cells 27:783-95. 2009
  3. pmc The CD4 molecule on CD8+ T lymphocytes directly enhances the immune response to viral and cellular antigens
    Scott G Kitchen
    Department of Medicine, and UCLA AIDS Institute, David Geffen School of Medicine, University of California Los Angeles, 10833 Le Conte Avenue, Los Angeles, CA 90095, USA
    Proc Natl Acad Sci U S A 102:3794-9. 2005
  4. pmc T lineage differentiation from human embryonic stem cells
    Zoran Galic
    Department of Medicine, UCLA AIDS Institute, David Geffen School of Medicine, University of California, Los Angeles, CA 90095 1678, USA
    Proc Natl Acad Sci U S A 103:11742-7. 2006
  5. pmc A highly efficient short hairpin RNA potently down-regulates CCR5 expression in systemic lymphoid organs in the hu-BLT mouse model
    Saki Shimizu
    Department of Medicine, Division of Hematology Oncology, UCLA AIDS Institute, David Geffen School of Medicine, University of California Los Angeles, 615 Charles E Young Drive South, Los Angeles, CA 90095, USA
    Blood 115:1534-44. 2010
  6. ncbi request reprint Controlling false-negative errors in microarray differential expression analysis: a PRIM approach
    Steve W Cole
    Department of Medicine, Immunology, and Molecular Genetics, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095 1678, USA
    Bioinformatics 19:1808-16. 2003
  7. pmc Engineering antigen-specific T cells from genetically modified human hematopoietic stem cells in immunodeficient mice
    Scott G Kitchen
    Division of Hematology Oncology, The David Geffen School of Medicine at University of California Los Angeles, Los Angeles, California, United States of America
    PLoS ONE 4:e8208. 2009
  8. pmc Antitumor activity from antigen-specific CD8 T cells generated in vivo from genetically engineered human hematopoietic stem cells
    Dimitrios N Vatakis
    Department of Medicine, Division of Hematology Oncology, David Geffen School of Medicine at the University of California, Los Angeles CA 90095, USA
    Proc Natl Acad Sci U S A 108:E1408-16. 2011
  9. pmc A functional link between Wnt signaling and SKP2-independent p27 turnover in mammary tumors
    Gustavo A Miranda-Carboni
    Department of Obstetrics and Gynecology, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, California 90095, USA
    Genes Dev 22:3121-34. 2008
  10. pmc A self-renewal program controls the expansion of genetically unstable cancer stem cells in pluripotent stem cell-derived tumors
    Anne E Conway
    Department of Molecular Cell and Developmental Biology, University of California, Los Angeles, USA
    Stem Cells 27:18-28. 2009

Collaborators

Detail Information

Publications14

  1. pmc Generation of T lineage cells from human embryonic stem cells in a feeder free system
    Zoran Galic
    Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, 90095, USA
    Stem Cells 27:100-7. 2009
    ....
  2. doi request reprint Derivation of primordial germ cells from human embryonic and induced pluripotent stem cells is significantly improved by coculture with human fetal gonadal cells
    Tae Sub Park
    Department of Molecular Cell and Developmental Biology, University of California, Los Angeles, CA, USA
    Stem Cells 27:783-95. 2009
    ....
  3. pmc The CD4 molecule on CD8+ T lymphocytes directly enhances the immune response to viral and cellular antigens
    Scott G Kitchen
    Department of Medicine, and UCLA AIDS Institute, David Geffen School of Medicine, University of California Los Angeles, 10833 Le Conte Avenue, Los Angeles, CA 90095, USA
    Proc Natl Acad Sci U S A 102:3794-9. 2005
    ..Therefore, CD4 expression on CD8 T lymphocytes modulates cytotoxic T lymphocyte function and is critical in vivo for optimal cell-mediated immunity to viral and alloantigens...
  4. pmc T lineage differentiation from human embryonic stem cells
    Zoran Galic
    Department of Medicine, UCLA AIDS Institute, David Geffen School of Medicine, University of California, Los Angeles, CA 90095 1678, USA
    Proc Natl Acad Sci U S A 103:11742-7. 2006
    ..Stable transgene expression was maintained at high levels throughout differentiation, suggesting that genetically manipulated hESC hold potential to treat several T cell disorders...
  5. pmc A highly efficient short hairpin RNA potently down-regulates CCR5 expression in systemic lymphoid organs in the hu-BLT mouse model
    Saki Shimizu
    Department of Medicine, Division of Hematology Oncology, UCLA AIDS Institute, David Geffen School of Medicine, University of California Los Angeles, 615 Charles E Young Drive South, Los Angeles, CA 90095, USA
    Blood 115:1534-44. 2010
    ..These results demonstrate that lentiviral vector delivery of shRNA into human HPSCs could stably down-regulate CCR5 in systemic lymphoid organs in vivo...
  6. ncbi request reprint Controlling false-negative errors in microarray differential expression analysis: a PRIM approach
    Steve W Cole
    Department of Medicine, Immunology, and Molecular Genetics, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095 1678, USA
    Bioinformatics 19:1808-16. 2003
    ....
  7. pmc Engineering antigen-specific T cells from genetically modified human hematopoietic stem cells in immunodeficient mice
    Scott G Kitchen
    Division of Hematology Oncology, The David Geffen School of Medicine at University of California Los Angeles, Los Angeles, California, United States of America
    PLoS ONE 4:e8208. 2009
    ....
  8. pmc Antitumor activity from antigen-specific CD8 T cells generated in vivo from genetically engineered human hematopoietic stem cells
    Dimitrios N Vatakis
    Department of Medicine, Division of Hematology Oncology, David Geffen School of Medicine at the University of California, Los Angeles CA 90095, USA
    Proc Natl Acad Sci U S A 108:E1408-16. 2011
    ..These studies present a potential therapeutic approach and an important tool to understand better and to optimize the human immune response to melanoma and, potentially, to other types of cancer...
  9. pmc A functional link between Wnt signaling and SKP2-independent p27 turnover in mammary tumors
    Gustavo A Miranda-Carboni
    Department of Obstetrics and Gynecology, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, California 90095, USA
    Genes Dev 22:3121-34. 2008
    ..CUL4A and CUL4B are therefore components of a conserved Wnt-induced proteasome targeting (WIPT) complex that regulates p27(KIP1) levels and cell cycle progression in mammalian cells...
  10. pmc A self-renewal program controls the expansion of genetically unstable cancer stem cells in pluripotent stem cell-derived tumors
    Anne E Conway
    Department of Molecular Cell and Developmental Biology, University of California, Los Angeles, USA
    Stem Cells 27:18-28. 2009
    ....
  11. pmc beta-Adrenoreceptors reactivate Kaposi's sarcoma-associated herpesvirus lytic replication via PKA-dependent control of viral RTA
    Margaret Chang
    Department of Microbiology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095 1678, USA
    J Virol 79:13538-47. 2005
    ..These findings also suggest novel therapeutic strategies for controlling the activity of this oncogenic gammaherpesvirus in vivo...
  12. ncbi request reprint Expression-based monitoring of transcription factor activity: the TELiS database
    Steve W Cole
    UCLA Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095 1678, USA
    Bioinformatics 21:803-10. 2005
    ..The interlocking JAVA applications namely, PromoterScan and PromoterStats carry out these tasks, and together constitute the TELiS database for reverse inference of transcription factor activity...
  13. pmc CD4 on CD8(+) T cells directly enhances effector function and is a target for HIV infection
    Scott G Kitchen
    Department of Medicine and Microbiology, David Geffen School of Medicine, University of California, 11 934 Factor Building, 10833 Le Conte Avenue, Los Angeles, CA 90095, USA
    Proc Natl Acad Sci U S A 101:8727-32. 2004
    ..Thus, the CD4 molecule plays a direct role in CD8 T cell function, and infection of these cells by HIV provides an additional reservoir for the virus and also may contribute to the immunodeficiency seen in HIV disease...
  14. ncbi request reprint Combinatorial regulation of the murine RAG-2 promoter by Sp1 and distinct lymphocyte-specific transcription factors
    Gustavo A Miranda
    Department of Molecular, Cell and Developmental Biology, University of California, Los Angeles 405 Hilgard Ave, Los Angeles, CA 90095 1606, USA
    Mol Immunol 38:1151-9. 2002
    ..Apart from showing that Sp1 interacts within the RAG-2 promoter, we also demonstrate that the Sp1-binding site is necessary for the high-level activation of this promoter...