Krishna K Gaddam

Summary

Affiliation: University of Alabama at Birmingham
Country: USA

Publications

  1. ncbi request reprint Aldosterone antagonists: effective add-on therapy for the treatment of resistant hypertension
    Krishna K Gaddam
    Vascular Biology and Hypertension Program, University of Alabama at Birmingham, 115 Community Health Services Building, 933 19 Street South, Birmingham, AL 35294, USA
    Expert Rev Cardiovasc Ther 4:353-9. 2006
  2. pmc Characterization of resistant hypertension: association between resistant hypertension, aldosterone, and persistent intravascular volume expansion
    Krishna K Gaddam
    Vascular Biology and Hypertension Program, University of Alabama at Birmingham, 933 19th St S, Community Health Services Bldg 115, Birmingham, AL 35294, USA
    Arch Intern Med 168:1159-64. 2008
  3. ncbi request reprint Aldosterone excess and resistance to 24-h blood pressure control
    Eduardo Pimenta
    Vascular Biology and Hypertension Program, University of Alabama at Birmingham, Birmingham, Alabama, USA
    J Hypertens 25:2131-7. 2007
  4. pmc Severity of obstructive sleep apnea is related to aldosterone status in subjects with resistant hypertension
    Carolina C Gonzaga
    Vascular Biology and Hypertension Program, Division of Cardiovascular Disease, University of Alabama at Birmingham, AL, USA
    J Clin Sleep Med 6:363-8. 2010
  5. ncbi request reprint Relation of dietary salt and aldosterone to urinary protein excretion in subjects with resistant hypertension
    Eduardo Pimenta
    Vascular Biology and Hypertension Program, University of Alabama at Birmingham, AL, USA
    Hypertension 51:339-44. 2008
  6. ncbi request reprint Mechanisms and treatment of resistant hypertension
    Eduardo Pimenta
    Vascular Biology and Hypertension Program, University of Alabama at Birmingham, 933 19th Street South, Birmingham, AL 35294, USA
    J Clin Hypertens (Greenwich) 10:239-44. 2008
  7. pmc Relation of torsion and myocardial strains to LV ejection fraction in hypertension
    Mustafa I Ahmed
    Division of Cardiovascular Medicine, Department of Medicine, University of Alabama at Birmingham, 1530 3rd Avenue South, Birmingham, AL 35294, USA
    JACC Cardiovasc Imaging 5:273-81. 2012
  8. doi request reprint Renin inhibition: should it supplant ACE inhibitors and ARBS in high risk patients?
    Krishna K Gaddam
    Vascular Biology and Hypertension Program, Division of Cardiovascular Diseases, University of Alabama at Birmingham, Birmingham, Alabama, USA
    Curr Opin Nephrol Hypertens 17:484-90. 2008
  9. ncbi request reprint Diastolic dysfunction and heart failure with preserved ejection fraction: rationale for RAAS antagonist/CCB combination therapy
    Krishna K Gaddam
    Vascular Biology and Hypertension Program, University of Alabama at Birmingham, Birmingham, Alabama, USA
    J Am Soc Hypertens 3:52-68. 2009

Detail Information

Publications9

  1. ncbi request reprint Aldosterone antagonists: effective add-on therapy for the treatment of resistant hypertension
    Krishna K Gaddam
    Vascular Biology and Hypertension Program, University of Alabama at Birmingham, 115 Community Health Services Building, 933 19 Street South, Birmingham, AL 35294, USA
    Expert Rev Cardiovasc Ther 4:353-9. 2006
    ..These agents are generally well tolerated. Hyperkalemia is an uncommon complication of aldosterone antagonists, but it can occur. Therefore, biochemical monitoring is necessary, particularly in high-risk patients...
  2. pmc Characterization of resistant hypertension: association between resistant hypertension, aldosterone, and persistent intravascular volume expansion
    Krishna K Gaddam
    Vascular Biology and Hypertension Program, University of Alabama at Birmingham, 933 19th St S, Community Health Services Bldg 115, Birmingham, AL 35294, USA
    Arch Intern Med 168:1159-64. 2008
    ..Resistant hypertension is a common clinical problem and greatly increases the risk of target organ damage...
  3. ncbi request reprint Aldosterone excess and resistance to 24-h blood pressure control
    Eduardo Pimenta
    Vascular Biology and Hypertension Program, University of Alabama at Birmingham, Birmingham, Alabama, USA
    J Hypertens 25:2131-7. 2007
    ..Aldosterone excess has been reported to be a common cause of resistant hypertension. To what degree this represents true treatment resistance is unknown...
  4. pmc Severity of obstructive sleep apnea is related to aldosterone status in subjects with resistant hypertension
    Carolina C Gonzaga
    Vascular Biology and Hypertension Program, Division of Cardiovascular Disease, University of Alabama at Birmingham, AL, USA
    J Clin Sleep Med 6:363-8. 2010
    ..This investigation examines the relationship between aldosterone status and OSA in patients with resistant hypertensive-with and without hyperaldosteronism...
  5. ncbi request reprint Relation of dietary salt and aldosterone to urinary protein excretion in subjects with resistant hypertension
    Eduardo Pimenta
    Vascular Biology and Hypertension Program, University of Alabama at Birmingham, AL, USA
    Hypertension 51:339-44. 2008
    ..003) was observed in subjects with high Ualdo but not in subjects with normal Ualdo (r=0.18; P value not significant). These results suggest that aldosterone excess and high dietary salt combine to increase urinary protein excretion...
  6. ncbi request reprint Mechanisms and treatment of resistant hypertension
    Eduardo Pimenta
    Vascular Biology and Hypertension Program, University of Alabama at Birmingham, 933 19th Street South, Birmingham, AL 35294, USA
    J Clin Hypertens (Greenwich) 10:239-44. 2008
    ..Recent studies indicate that the addition of spironolactone to standard treatment induces significant BP reduction in most patients with resistant hypertension...
  7. pmc Relation of torsion and myocardial strains to LV ejection fraction in hypertension
    Mustafa I Ahmed
    Division of Cardiovascular Medicine, Department of Medicine, University of Alabama at Birmingham, 1530 3rd Avenue South, Birmingham, AL 35294, USA
    JACC Cardiovasc Imaging 5:273-81. 2012
    ..The goal of this study was to define the mechanism of preserved ejection fraction (EF) despite depressed myocardial strains in hypertension (HTN)...
  8. doi request reprint Renin inhibition: should it supplant ACE inhibitors and ARBS in high risk patients?
    Krishna K Gaddam
    Vascular Biology and Hypertension Program, Division of Cardiovascular Diseases, University of Alabama at Birmingham, Birmingham, Alabama, USA
    Curr Opin Nephrol Hypertens 17:484-90. 2008
    ..In this review, we discuss the potential advantages and disadvantages of this newest antihypertensive class over other available RAAS antagonists...
  9. ncbi request reprint Diastolic dysfunction and heart failure with preserved ejection fraction: rationale for RAAS antagonist/CCB combination therapy
    Krishna K Gaddam
    Vascular Biology and Hypertension Program, University of Alabama at Birmingham, Birmingham, Alabama, USA
    J Am Soc Hypertens 3:52-68. 2009
    ..Combination therapy using an antagonist of the renin-angiotensin-aldosterone system and a calcium-channel blocker has potential advantages over monotherapy and is being explored in several ongoing clinical trials...