B Ann T Gabelt

Summary

Affiliation: University of Wisconsin
Country: USA

Publications

  1. pmc Effect of nitric oxide compounds on monkey ciliary muscle in vitro
    B Ann T Gabelt
    Department of Ophthalmology and Visual Sciences, University of Wisconsin, 600 Highland Ave, Madison, WI 53792, United States
    Exp Eye Res 93:321-7. 2011
  2. ncbi request reprint Caldesmon transgene expression disrupts focal adhesions in HTM cells and increases outflow facility in organ-cultured human and monkey anterior segments
    B Ann True Gabelt
    Department of Ophthalmology and Visual Sciences, University of Wisconsin, Madison, WI 53792, USA
    Exp Eye Res 82:935-44. 2006
  3. ncbi request reprint Aqueous humor dynamics in monkeys after topical R-DOI
    B Ann T Gabelt
    Ophthalmology and Visual Sciences, University of Wisconsin, Madison, Wisconsin 53792 3220, USA
    Invest Ophthalmol Vis Sci 46:4691-6. 2005
  4. ncbi request reprint The effect of C3 transgene expression on actin and cellular adhesions in cultured human trabecular meshwork cells and on outflow facility in organ cultured monkey eyes
    Xuyang Liu
    Department of Ophthalmology and Visual Sciences, University of Wisconsin Medical School, Madison, WI, USA
    Mol Vis 11:1112-21. 2005
  5. pmc Heparin II domain of fibronectin mediates contractility through an alpha4beta1 co-signaling pathway
    Marie K Schwinn
    Department of Pathology and Laboratory Medicine, University of Wisconsin Madison School of Medicine and Public Health, Madison, WI 53706, USA
    Exp Cell Res 316:1500-12. 2010
  6. pmc Effect of nitric oxide on anterior segment physiology in monkeys
    Galen W Heyne
    Department of Ophthalmology and Visual Sciences, University of Wisconsin, Madison, Wisconsin, USA
    Invest Ophthalmol Vis Sci 54:5103-10. 2013
  7. ncbi request reprint Eyelid lymphatics I: histochemical comparisons between the monkey and human
    Briggs E Cook
    Department of Ophthalmology and Visual Sciences, University of Wisconsin Madison, USA
    Ophthal Plast Reconstr Surg 18:18-23. 2002
  8. pmc Identification of the active site in the heparin II domain of fibronectin that increases outflow facility in cultured monkey anterior segments
    Jose M Gonzalez
    Department of Pathology and Laboratory Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI 53706, USA
    Invest Ophthalmol Vis Sci 50:235-41. 2009
  9. ncbi request reprint Aqueous humor dynamics in monkeys after topical 8-iso PGE(2)
    B Ann T Gabelt
    Department of Ophthalmology and Visual Sciences, University of Wisconsin, Madison, WI 53792, USA
    Invest Ophthalmol Vis Sci 45:892-9. 2004
  10. pmc Relationship of aqueous outflow resistance to age and total volume perfused in rhesus and cynomolgus monkeys
    Julie A Kiland
    Department of Ophthalmology and Visual Sciences, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin 53792, USA
    Invest Ophthalmol Vis Sci 52:6820-4. 2011

Collaborators

Detail Information

Publications18

  1. pmc Effect of nitric oxide compounds on monkey ciliary muscle in vitro
    B Ann T Gabelt
    Department of Ophthalmology and Visual Sciences, University of Wisconsin, 600 Highland Ave, Madison, WI 53792, United States
    Exp Eye Res 93:321-7. 2011
    ..Nitric oxide generating compounds may have potential value in therapeutic areas where modulation of ciliary muscle tension is desirable...
  2. ncbi request reprint Caldesmon transgene expression disrupts focal adhesions in HTM cells and increases outflow facility in organ-cultured human and monkey anterior segments
    B Ann True Gabelt
    Department of Ophthalmology and Visual Sciences, University of Wisconsin, Madison, WI 53792, USA
    Exp Eye Res 82:935-44. 2006
    ..This suggests that over-expression of the caldesmon gene in the TM may be an effective approach for the gene therapy of glaucoma...
  3. ncbi request reprint Aqueous humor dynamics in monkeys after topical R-DOI
    B Ann T Gabelt
    Ophthalmology and Visual Sciences, University of Wisconsin, Madison, Wisconsin 53792 3220, USA
    Invest Ophthalmol Vis Sci 46:4691-6. 2005
    ..To determine the effects of R-DOI, a selective 5-HT2 agonist, on intraocular pressure (IOP) and aqueous humor dynamics in monkeys...
  4. ncbi request reprint The effect of C3 transgene expression on actin and cellular adhesions in cultured human trabecular meshwork cells and on outflow facility in organ cultured monkey eyes
    Xuyang Liu
    Department of Ophthalmology and Visual Sciences, University of Wisconsin Medical School, Madison, WI, USA
    Mol Vis 11:1112-21. 2005
    ..To determine the effects of adenovirus-delivered exoenzyme C3 transferase (C3) gene expression on cultured human trabecular meshwork (HTM) cells and on outflow facility in organ cultured monkey anterior segments...
  5. pmc Heparin II domain of fibronectin mediates contractility through an alpha4beta1 co-signaling pathway
    Marie K Schwinn
    Department of Pathology and Laboratory Medicine, University of Wisconsin Madison School of Medicine and Public Health, Madison, WI 53706, USA
    Exp Cell Res 316:1500-12. 2010
    ..This is the first time that the PPRARI sequence in the HepII domain has been shown to serve as a physiological alpha4beta1 ligand, suggesting that alpha4beta1 integrin may be a key regulator of tissue contractility...
  6. pmc Effect of nitric oxide on anterior segment physiology in monkeys
    Galen W Heyne
    Department of Ophthalmology and Visual Sciences, University of Wisconsin, Madison, Wisconsin, USA
    Invest Ophthalmol Vis Sci 54:5103-10. 2013
    ....
  7. ncbi request reprint Eyelid lymphatics I: histochemical comparisons between the monkey and human
    Briggs E Cook
    Department of Ophthalmology and Visual Sciences, University of Wisconsin Madison, USA
    Ophthal Plast Reconstr Surg 18:18-23. 2002
    ..To study the lymphatic drainage of the cynomolgus monkey and human eyelid and periocular tissue by means of histochemistry...
  8. pmc Identification of the active site in the heparin II domain of fibronectin that increases outflow facility in cultured monkey anterior segments
    Jose M Gonzalez
    Department of Pathology and Laboratory Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI 53706, USA
    Invest Ophthalmol Vis Sci 50:235-41. 2009
    ..To determine the active site in the Heparin II (HepII) domain of fibronectin that regulates outflow facility in cultured anterior segments and disrupts the actin cytoskeleton in transformed human trabecular meshwork (TM-1) cells...
  9. ncbi request reprint Aqueous humor dynamics in monkeys after topical 8-iso PGE(2)
    B Ann T Gabelt
    Department of Ophthalmology and Visual Sciences, University of Wisconsin, Madison, WI 53792, USA
    Invest Ophthalmol Vis Sci 45:892-9. 2004
    ..To determine in normotensive cynomolgus monkeys, the effects of topical 8-iso prostaglandin (PG)E(2) on intraocular pressure (IOP), aqueous humor formation (AHF), uveoscleral outflow (Fu), and total and trabecular outflow facility...
  10. pmc Relationship of aqueous outflow resistance to age and total volume perfused in rhesus and cynomolgus monkeys
    Julie A Kiland
    Department of Ophthalmology and Visual Sciences, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin 53792, USA
    Invest Ophthalmol Vis Sci 52:6820-4. 2011
    ..The effect of total volume perfused on outflow resistance (the reciprocal of outflow facility) and the effect of age on the rate of change in resistance as a function of total volume were determined in rhesus and cynomolgus monkeys...
  11. pmc Effect of the age cross-link breaker alagebrium on anterior segment physiology, morphology, and ocular age and rage
    Julie A Kiland
    Department of Ophthalmology and Visual Sciences, University of Wisconsin, Madison, USA
    Trans Am Ophthalmol Soc 107:146-58. 2009
    ....
  12. ncbi request reprint Differential expression of matrix metalloproteinases in monkey eyes with experimental glaucoma or optic nerve transection
    Olga A Agapova
    Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, 660 S Euclid Avenue, Box 8096, St Louis, MO 63110, USA
    Brain Res 967:132-43. 2003
    ..Increased MMP1 and MT1-MMP1 expression in the glaucomatous optic nerve head is specific to tissue remodeling due to elevated intraocular pressure and not secondary to loss of axons...
  13. pmc 1α,25-Dihydroxyvitamin D(3) and its analog, 2-methylene-19-nor-(20S)-1α,25-dihydroxyvitamin D(3) (2MD), suppress intraocular pressure in non-human primates
    Galina D Kutuzova
    Department of Biochemistry, University of Wisconsin Madison, Madison, WI 53706 1544, United States
    Arch Biochem Biophys 518:53-60. 2012
    ..Nevertheless, our results suggest that 1α,25-(OH)(2)D(3), or an analog thereof, may present a new approach to the treatment of glaucoma...
  14. pmc The role of the actomyosin system in regulating trabecular fluid outflow
    Baohe Tian
    Department of Ophthalmology and Visual Sciences, University of Wisconsin, Madison, WI 53792 3220, USA
    Exp Eye Res 88:713-7. 2009
    ..In this review, we discuss the mechanisms underlying these and similar effects on trabecular outflow resistance in living animals and/or in cultured ocular anterior segments from enucleated animal or human eyes...
  15. pmc Structure/function studies and the effects of memantine in monkeys with experimental glaucoma
    B Ann T Gabelt
    Department of Ophthalmology and Visual Sciences, University of Wisconsin Madison, Madison, Wisconsin 53705, USA
    Invest Ophthalmol Vis Sci 53:2368-76. 2012
    ..These structural changes may or may not lead to central functional changes as shown by the mfVEP in response to investigational therapies...
  16. pmc Effect of daily prolonged ketamine anesthesia on intraocular pressure in monkeys
    Theodora J Bunch
    Department of Ophthalmology and Visual Sciences, University of Wisconsin, Madison, Wisconsin 53705 2135, USA
    Curr Eye Res 33:946-53. 2008
    ....
  17. ncbi request reprint H-7 effect on outflow facility after trabecular obstruction following long-term echothiophate treatment in monkeys
    B Ann T Gabelt
    Department of Ophthalmology and Visual Sciences, University of Wisconsin, Madison, 53792, USA
    Invest Ophthalmol Vis Sci 45:2732-6. 2004
    ..To determine whether H-7 can enhance outflow facility after trabecular meshwork obstruction by extracellular material that accumulates after long-term treatment of monkeys with the cholinesterase inhibitor echothiophate iodide (ECHO)...
  18. ncbi request reprint Eyelid lymphatics II: a search for drainage patterns in the monkey and correlations with human lymphatics
    Briggs E Cook
    Department of Ophthalmology and Visual Sciences, University of Wisconsin Madison, Wisconsin, USA
    Ophthal Plast Reconstr Surg 18:99-106. 2002
    ..To study the lymphatic drainage of the cynomolgus monkey through the use of lymphoscintigraphy...