B Ann T Gabelt

Summary

Affiliation: University of Wisconsin
Country: USA

Publications

  1. ncbi request reprint Aqueous humor dynamics in monkeys after topical R-DOI
    B Ann T Gabelt
    Ophthalmology and Visual Sciences, University of Wisconsin, Madison, Wisconsin 53792 3220, USA
    Invest Ophthalmol Vis Sci 46:4691-6. 2005
  2. ncbi request reprint Caldesmon transgene expression disrupts focal adhesions in HTM cells and increases outflow facility in organ-cultured human and monkey anterior segments
    B Ann True Gabelt
    Department of Ophthalmology and Visual Sciences, University of Wisconsin, Madison, WI 53792, USA
    Exp Eye Res 82:935-44. 2006
  3. pmc Effect of nitric oxide compounds on monkey ciliary muscle in vitro
    B Ann T Gabelt
    Department of Ophthalmology and Visual Sciences, University of Wisconsin, 600 Highland Ave, Madison, WI 53792, United States
    Exp Eye Res 93:321-7. 2011
  4. pmc Heparin II domain of fibronectin mediates contractility through an alpha4beta1 co-signaling pathway
    Marie K Schwinn
    Department of Pathology and Laboratory Medicine, University of Wisconsin Madison School of Medicine and Public Health, Madison, WI 53706, USA
    Exp Cell Res 316:1500-12. 2010
  5. ncbi request reprint Eyelid lymphatics I: histochemical comparisons between the monkey and human
    Briggs E Cook
    Department of Ophthalmology and Visual Sciences, University of Wisconsin Madison, USA
    Ophthal Plast Reconstr Surg 18:18-23. 2002
  6. pmc Identification of the active site in the heparin II domain of fibronectin that increases outflow facility in cultured monkey anterior segments
    Jose M Gonzalez
    Department of Pathology and Laboratory Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI 53706, USA
    Invest Ophthalmol Vis Sci 50:235-41. 2009
  7. pmc Relationship of aqueous outflow resistance to age and total volume perfused in rhesus and cynomolgus monkeys
    Julie A Kiland
    Department of Ophthalmology and Visual Sciences, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin 53792, USA
    Invest Ophthalmol Vis Sci 52:6820-4. 2011
  8. pmc Effect of the age cross-link breaker alagebrium on anterior segment physiology, morphology, and ocular age and rage
    Julie A Kiland
    Department of Ophthalmology and Visual Sciences, University of Wisconsin, Madison, USA
    Trans Am Ophthalmol Soc 107:146-58. 2009
  9. pmc 1α,25-Dihydroxyvitamin D(3) and its analog, 2-methylene-19-nor-(20S)-1α,25-dihydroxyvitamin D(3) (2MD), suppress intraocular pressure in non-human primates
    Galina D Kutuzova
    Department of Biochemistry, University of Wisconsin Madison, Madison, WI 53706 1544, United States
    Arch Biochem Biophys 518:53-60. 2012
  10. pmc The role of the actomyosin system in regulating trabecular fluid outflow
    Baohe Tian
    Department of Ophthalmology and Visual Sciences, University of Wisconsin, Madison, WI 53792 3220, USA
    Exp Eye Res 88:713-7. 2009

Collaborators

Detail Information

Publications15

  1. ncbi request reprint Aqueous humor dynamics in monkeys after topical R-DOI
    B Ann T Gabelt
    Ophthalmology and Visual Sciences, University of Wisconsin, Madison, Wisconsin 53792 3220, USA
    Invest Ophthalmol Vis Sci 46:4691-6. 2005
    ..To determine the effects of R-DOI, a selective 5-HT2 agonist, on intraocular pressure (IOP) and aqueous humor dynamics in monkeys...
  2. ncbi request reprint Caldesmon transgene expression disrupts focal adhesions in HTM cells and increases outflow facility in organ-cultured human and monkey anterior segments
    B Ann True Gabelt
    Department of Ophthalmology and Visual Sciences, University of Wisconsin, Madison, WI 53792, USA
    Exp Eye Res 82:935-44. 2006
    ..This suggests that over-expression of the caldesmon gene in the TM may be an effective approach for the gene therapy of glaucoma...
  3. pmc Effect of nitric oxide compounds on monkey ciliary muscle in vitro
    B Ann T Gabelt
    Department of Ophthalmology and Visual Sciences, University of Wisconsin, 600 Highland Ave, Madison, WI 53792, United States
    Exp Eye Res 93:321-7. 2011
    ..Nitric oxide generating compounds may have potential value in therapeutic areas where modulation of ciliary muscle tension is desirable...
  4. pmc Heparin II domain of fibronectin mediates contractility through an alpha4beta1 co-signaling pathway
    Marie K Schwinn
    Department of Pathology and Laboratory Medicine, University of Wisconsin Madison School of Medicine and Public Health, Madison, WI 53706, USA
    Exp Cell Res 316:1500-12. 2010
    ..This is the first time that the PPRARI sequence in the HepII domain has been shown to serve as a physiological alpha4beta1 ligand, suggesting that alpha4beta1 integrin may be a key regulator of tissue contractility...
  5. ncbi request reprint Eyelid lymphatics I: histochemical comparisons between the monkey and human
    Briggs E Cook
    Department of Ophthalmology and Visual Sciences, University of Wisconsin Madison, USA
    Ophthal Plast Reconstr Surg 18:18-23. 2002
    ..To study the lymphatic drainage of the cynomolgus monkey and human eyelid and periocular tissue by means of histochemistry...
  6. pmc Identification of the active site in the heparin II domain of fibronectin that increases outflow facility in cultured monkey anterior segments
    Jose M Gonzalez
    Department of Pathology and Laboratory Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI 53706, USA
    Invest Ophthalmol Vis Sci 50:235-41. 2009
    ..To determine the active site in the Heparin II (HepII) domain of fibronectin that regulates outflow facility in cultured anterior segments and disrupts the actin cytoskeleton in transformed human trabecular meshwork (TM-1) cells...
  7. pmc Relationship of aqueous outflow resistance to age and total volume perfused in rhesus and cynomolgus monkeys
    Julie A Kiland
    Department of Ophthalmology and Visual Sciences, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin 53792, USA
    Invest Ophthalmol Vis Sci 52:6820-4. 2011
    ..The effect of total volume perfused on outflow resistance (the reciprocal of outflow facility) and the effect of age on the rate of change in resistance as a function of total volume were determined in rhesus and cynomolgus monkeys...
  8. pmc Effect of the age cross-link breaker alagebrium on anterior segment physiology, morphology, and ocular age and rage
    Julie A Kiland
    Department of Ophthalmology and Visual Sciences, University of Wisconsin, Madison, USA
    Trans Am Ophthalmol Soc 107:146-58. 2009
    ....
  9. pmc 1α,25-Dihydroxyvitamin D(3) and its analog, 2-methylene-19-nor-(20S)-1α,25-dihydroxyvitamin D(3) (2MD), suppress intraocular pressure in non-human primates
    Galina D Kutuzova
    Department of Biochemistry, University of Wisconsin Madison, Madison, WI 53706 1544, United States
    Arch Biochem Biophys 518:53-60. 2012
    ..Nevertheless, our results suggest that 1α,25-(OH)(2)D(3), or an analog thereof, may present a new approach to the treatment of glaucoma...
  10. pmc The role of the actomyosin system in regulating trabecular fluid outflow
    Baohe Tian
    Department of Ophthalmology and Visual Sciences, University of Wisconsin, Madison, WI 53792 3220, USA
    Exp Eye Res 88:713-7. 2009
    ..In this review, we discuss the mechanisms underlying these and similar effects on trabecular outflow resistance in living animals and/or in cultured ocular anterior segments from enucleated animal or human eyes...
  11. doi request reprint Structure/function studies and the effects of memantine in monkeys with experimental glaucoma
    B Ann T Gabelt
    Department of Ophthalmology and Visual Sciences, University of Wisconsin Madison, Madison, Wisconsin 53705, USA
    Invest Ophthalmol Vis Sci 53:2368-76. 2012
    ..These structural changes may or may not lead to central functional changes as shown by the mfVEP in response to investigational therapies...
  12. ncbi request reprint H-7 effect on outflow facility after trabecular obstruction following long-term echothiophate treatment in monkeys
    B Ann T Gabelt
    Department of Ophthalmology and Visual Sciences, University of Wisconsin, Madison, 53792, USA
    Invest Ophthalmol Vis Sci 45:2732-6. 2004
    ..To determine whether H-7 can enhance outflow facility after trabecular meshwork obstruction by extracellular material that accumulates after long-term treatment of monkeys with the cholinesterase inhibitor echothiophate iodide (ECHO)...
  13. pmc Effect of daily prolonged ketamine anesthesia on intraocular pressure in monkeys
    Theodora J Bunch
    Department of Ophthalmology and Visual Sciences, University of Wisconsin, Madison, Wisconsin 53705 2135, USA
    Curr Eye Res 33:946-53. 2008
    ....
  14. pmc Effect of nitric oxide on anterior segment physiology in monkeys
    Galen W Heyne
    Department of Ophthalmology and Visual Sciences, University of Wisconsin, Madison, Wisconsin, USA
    Invest Ophthalmol Vis Sci 54:5103-10. 2013
    ....
  15. ncbi request reprint Eyelid lymphatics II: a search for drainage patterns in the monkey and correlations with human lymphatics
    Briggs E Cook
    Department of Ophthalmology and Visual Sciences, University of Wisconsin Madison, Wisconsin, USA
    Ophthal Plast Reconstr Surg 18:99-106. 2002
    ..To study the lymphatic drainage of the cynomolgus monkey through the use of lymphoscintigraphy...