Kar Ming Fung

Summary

Affiliation: University of Oklahoma Health Sciences Center
Country: USA

Publications

  1. pmc Intravascular large B-cell lymphoma with hemophagocytic syndrome (Asian variant) in a Caucasian patient
    Kar Ming Fung
    Department of Pathology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA
    Int J Clin Exp Pathol 5:448-54. 2012
  2. pmc Suppressed expression of type 2 3alpha/type 5 17beta-hydroxysteroid dehydrogenase (AKR1C3) in endometrial hyperplasia and carcinoma
    Vladislav Zakharov
    Department of Pathology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA
    Int J Clin Exp Pathol 3:608-17. 2010
  3. pmc Elevated AKR1C3 expression promotes prostate cancer cell survival and prostate cell-mediated endothelial cell tube formation: implications for prostate cancer progression
    Mikhail G Dozmorov
    Arthritis and Clinical Immunology Program, Oklahoma Medical Research Foundation, 825 N, E, 13th Street, Oklahoma City, Oklahoma 73104, USA
    BMC Cancer 10:672. 2010
  4. doi request reprint Regional variations in small intestinal submucosa evoke differences in inflammation with subsequent impact on tissue regeneration in the rat bladder augmentation model
    Richard A Ashley
    Department of Urology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA
    BJU Int 105:1462-8. 2010
  5. doi request reprint Developmental evaluation of aldo-keto reductase 1C3 expression in the cryptorchid testis
    Richard A Ashley
    Department of Urology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73104, USA
    Urology 76:67-72. 2010
  6. doi request reprint Leukocyte inflammatory response in a rat urinary bladder regeneration model using porcine small intestinal submucosa scaffold
    Richard A Ashley
    Department of Urology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73104, USA
    Tissue Eng Part A 15:3241-6. 2009
  7. pmc Aldo-keto reductase family 1 member C3 (AKR1C3) is expressed in adenocarcinoma and squamous cell carcinoma but not small cell carcinoma
    Valerie L Miller
    College of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA
    Int J Clin Exp Pathol 5:278-89. 2012
  8. pmc Expression of AKR1C3 in renal cell carcinoma, papillary urothelial carcinoma, and Wilms' tumor
    Joseph T Azzarello
    Department of Urology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA
    Int J Clin Exp Pathol 3:147-55. 2009
  9. doi request reprint The differential diagnosis of pilocytic astrocytoma with atypical features and malignant glioma: an analysis of 16 cases with emphasis on distinguishing molecular features
    Matthew D Cykowski
    Department of Pathology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA
    J Neurooncol 115:477-86. 2013
  10. doi request reprint Age-dependent vascular endothelial growth factor expression and angiogenic capability of bladder smooth muscle cells: implications for cell-seeded technology in bladder tissue engineering
    Joseph Azzarello
    Department of Urology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA
    J Tissue Eng Regen Med 3:579-89. 2009

Collaborators

Detail Information

Publications37

  1. pmc Intravascular large B-cell lymphoma with hemophagocytic syndrome (Asian variant) in a Caucasian patient
    Kar Ming Fung
    Department of Pathology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA
    Int J Clin Exp Pathol 5:448-54. 2012
    ..This case demonstrates the importance of high index of suspicion and astute histopathologic examination in recognition of this unusual clinical and pathologic combination...
  2. pmc Suppressed expression of type 2 3alpha/type 5 17beta-hydroxysteroid dehydrogenase (AKR1C3) in endometrial hyperplasia and carcinoma
    Vladislav Zakharov
    Department of Pathology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA
    Int J Clin Exp Pathol 3:608-17. 2010
    ..However, reduced AKR1C3 expression cannot distinguish hyperplastic endometrium from endometrial adenocarcinoma of endometrial type. The biologic and pathological roles of AKR1C3 in endometrial epithelium require further investigation...
  3. pmc Elevated AKR1C3 expression promotes prostate cancer cell survival and prostate cell-mediated endothelial cell tube formation: implications for prostate cancer progression
    Mikhail G Dozmorov
    Arthritis and Clinical Immunology Program, Oklahoma Medical Research Foundation, 825 N, E, 13th Street, Oklahoma City, Oklahoma 73104, USA
    BMC Cancer 10:672. 2010
    ..Here we propose a novel pathological function of AKR1C3 in tumor angiogenesis and its potential role in promoting PCa progression...
  4. doi request reprint Regional variations in small intestinal submucosa evoke differences in inflammation with subsequent impact on tissue regeneration in the rat bladder augmentation model
    Richard A Ashley
    Department of Urology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA
    BJU Int 105:1462-8. 2010
    ....
  5. doi request reprint Developmental evaluation of aldo-keto reductase 1C3 expression in the cryptorchid testis
    Richard A Ashley
    Department of Urology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73104, USA
    Urology 76:67-72. 2010
    ..AKR1C3 expression has been demonstrated in normal adult Leydig cells and peritubular fibromyocytes. No prior studies have evaluated AKR1C3 expression patterns across different age groups...
  6. doi request reprint Leukocyte inflammatory response in a rat urinary bladder regeneration model using porcine small intestinal submucosa scaffold
    Richard A Ashley
    Department of Urology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73104, USA
    Tissue Eng Part A 15:3241-6. 2009
    ..009). Thus, the inflammatory processes change over time during SIS-mediated bladder regeneration. Similar cell densities are present between the native and SIS portions of the bladder, but neutrophils predominate in the graft areas...
  7. pmc Aldo-keto reductase family 1 member C3 (AKR1C3) is expressed in adenocarcinoma and squamous cell carcinoma but not small cell carcinoma
    Valerie L Miller
    College of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA
    Int J Clin Exp Pathol 5:278-89. 2012
    ..AKR1C3 may serve as an adjunct marker for differentiating small cell carcinoma from NSCLC. However, roles of AKR1C3 in adenocarcinoma, squamous cell carcinoma, and small cell carcinoma pathogenesis require further studies...
  8. pmc Expression of AKR1C3 in renal cell carcinoma, papillary urothelial carcinoma, and Wilms' tumor
    Joseph T Azzarello
    Department of Urology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA
    Int J Clin Exp Pathol 3:147-55. 2009
    ..e., Wilms' tumor). Our results suggest that AKR1C3 may represent a developmental marker that is related to renal epithelium maturity...
  9. doi request reprint The differential diagnosis of pilocytic astrocytoma with atypical features and malignant glioma: an analysis of 16 cases with emphasis on distinguishing molecular features
    Matthew D Cykowski
    Department of Pathology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA
    J Neurooncol 115:477-86. 2013
    ....
  10. doi request reprint Age-dependent vascular endothelial growth factor expression and angiogenic capability of bladder smooth muscle cells: implications for cell-seeded technology in bladder tissue engineering
    Joseph Azzarello
    Department of Urology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA
    J Tissue Eng Regen Med 3:579-89. 2009
    ..Our results demonstrate that cell passage number is related to levels of VEGF production, which may translate to angiogenesis in engineered tissues...
  11. doi request reprint 5alpha-androstane-3alpha,17beta-diol supports human prostate cancer cell survival and proliferation through androgen receptor-independent signaling pathways: implication of androgen-independent prostate cancer progression
    Qing Yang
    Department of Urology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73104, USA
    J Cell Biochem 104:1612-24. 2008
    ..Future therapeutic strategies for treating advanced prostate cancer might need to target reductive 3alpha-HSD to block intraprostatic 3alpha-diol accumulation...
  12. doi request reprint AKR1C2 and AKR1C3 mediated prostaglandin D2 metabolism augments the PI3K/Akt proliferative signaling pathway in human prostate cancer cells
    Shaobin Wang
    Department of Urology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, United States
    Mol Cell Endocrinol 289:60-6. 2008
    ..Our results suggested that both AKR1C2 and AKR1C3 mediate similar PGD2 conversion toward the accumulation of proliferative signals through FP and PI3K/Akt signaling pathways to promote prostate cell proliferation...
  13. pmc Temporal expression of hyaluronic acid and hyaluronic acid receptors in a porcine small intestinal submucosa-augmented rat bladder regeneration model
    Fadee G Mondalek
    Department of Urology, University of Oklahoma Health Sciences Center, 920 Stanton L Young Blvd, WP3150, Oklahoma City, OK, 73104, USA
    World J Urol 33:1119-28. 2015
    ....
  14. doi request reprint Biomatrices for bladder reconstruction
    Hsueh Kung Lin
    Department of Urology, The Children s Hospital of Oklahoma, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA
    Adv Drug Deliv Rev 82:47-63. 2015
    ..Advanced molecular and medical technologies such as next generation sequencing and magnetic resonance imaging can be introduced for mechanistic understanding and non-invasive monitoring of regeneration processes, respectively. ..
  15. doi request reprint Pyrosequencing of IDH1 and IDH2 mutations in brain tumors and non-neoplastic conditions
    Matthew D Cykowski
    Department of Pathology, University of Oklahoma Health Sciences Center, Oklahoma City, USA
    Diagn Mol Pathol 21:214-20. 2012
    ..A significant association between IDH1/IDH2 mutation and 1p/19q deletion was also seen (Kendall τ coefficient=0.26, P=0.018), although several cases with 1p/19q deletion were IDH1/IDH2 wild type...
  16. pmc Understanding roles of porcine small intestinal submucosa in urinary bladder regeneration: identification of variable regenerative characteristics of small intestinal submucosa
    Hsueh Kung Lin
    1 Department of Urology, The Children s Hospital of Oklahoma, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma
    Tissue Eng Part B Rev 20:73-83. 2014
    ....
  17. doi request reprint Linking γ-aminobutyric acid A receptor to epidermal growth factor receptor pathways activation in human prostate cancer
    Weijuan Wu
    Department of Urology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA Department of Physiology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA
    Mol Cell Endocrinol 383:69-79. 2014
    ..These results suggest that the GABA signaling is linked to the EGFR pathway and may work through autocrine or paracine mechanism to promote CRPC progression...
  18. pmc Tissue distribution of human AKR1C3 and rat homolog in the adult genitourinary system
    Joseph Azzarello
    Department of Urology, University of Oklahoma Health Sciences Center, 800 Research Parkway, Room 462, Oklahoma City, OK 73034, USA
    J Histochem Cytochem 56:853-61. 2008
    ..These features warrant future studies of AKR1C3 in both hormone- and non-hormone-associated tissues and identification of the rodent homolog for establishing animal models...
  19. doi request reprint Internet and World Wide Web-based tools for neuropathology practice and education
    Kar Ming Fung
    Department of Pathology, University of Oklahoma Health Sciences Center, 940 Stanton Young Blvd, Oklahoma City, OK 73104, USA
    Brain Pathol 19:323-31. 2009
    ..We believe that our report and similar attempts can provide an opportunity to discuss appropriate and effective use of the Internet by the neuropathology community...
  20. pmc Increased expression of melanoma stem cell marker CD271 in metastatic melanoma to the brain
    Ruifeng Guo
    Department of Pathology, University of Oklahoma Health Sciences Center Oklahoma City, OK, USA
    Int J Clin Exp Pathol 7:8947-51. 2014
    ..Further prospective study for the role of CD271 in prediction of melanoma brain metastasis as well as prognosis assessment will be of great clinical significance. ..
  21. pmc Primary intracranial Ewing's sarcoma with unusual features
    Katherine A VandenHeuvel
    Department of Pathology, University of Oklahoma Health Sciences Center Oklahoma City, OK 73104, USA
    Int J Clin Exp Pathol 8:260-74. 2015
    ..Imaging often shows a supratentorial enhancing mass that touches the leptomeninges. Survival over three years is good but long term prognosis is unknown [3, 4]. ..
  22. pmc Differential expression of type 2 3α/type 5 17β-hydroxysteroid dehydrogenase (AKR1C3) in tumors of the central nervous system
    Aubrey L Park
    College of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA
    Int J Clin Exp Pathol 3:743-54. 2010
    ..Similar to AKR1C3 distribution in Wilm's tumor, we also demonstrate that expression of AKR1C3 is reduced in tumors with embryonic phenotypes...
  23. doi request reprint Primary Intracranial Sarcoma Presenting as Chronic Subdural Fluid Collections in a Child
    Chad A Glenn
    Department of Neurosurgery, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA Electronic address
    World Neurosurg 86:514.e13-8. 2016
    ..Primary intracranial sarcomas are uncommon entities. Diagnosis of sarcoma can be difficult because these lesions often manifest as apparent hematoma...
  24. ncbi request reprint Malignant rhabdoid tumor arising from a pleomorphic adenoma
    Kar Ming Fung
    Department of Pathology, The University of Oklahoma Health Science Center, Oklahoma City, OK, USA
    Ann Diagn Pathol 8:156-61. 2004
    ..The pathologic features of our case will be discussed in context with malignant rhabdoid tumors from other parts of the body...
  25. pmc Frankincense oil derived from Boswellia carteri induces tumor cell specific cytotoxicity
    Mark Barton Frank
    Department of Urology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA
    BMC Complement Altern Med 9:6. 2009
    ..The goal of this study was to evaluate frankincense oil for its anti-tumor activity and signaling pathways in bladder cancer cells...
  26. doi request reprint Temporal differentiation and maturation of regenerated rat urothelium
    Christopher C Roth
    Department of Urology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA
    BJU Int 103:836-41. 2009
    ....
  27. pmc Analysis of TMEFF2 allografts and transgenic mouse models reveals roles in prostate regeneration and cancer
    Joshua M Corbin
    Department of Pathology, Oklahoma University Health Sciences Center, Oklahoma City, Oklahoma
    Prostate 76:97-113. 2016
    ..Here, we further characterize this role and uncover new functions for TMEFF2 in cancer and adult prostate regeneration...
  28. doi request reprint Ectomesenchymoma with embryonal rhabdomyosarcoma and ganglioneuroma, arising in association with benign triton tumor of the tongue
    Katherine A VandenHeuvel
    1 Department of Pathology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA
    Pediatr Dev Pathol 17:226-30. 2014
    ..This lesion raises questions about the "benign" nature of benign triton tumor and its possible relationship to ectomesenchymoma...
  29. doi request reprint Intradural, extramedullary amyloidoma involving cervical and thoracic spine
    Adam D Smitherman
    Department of Neurosurgery, University of Oklahoma College of Medicine, Suite 400, 1000 North Lincoln Boulevard, Oklahoma City, OK 73104, USA Electronic address
    J Clin Neurosci 22:1052-4. 2015
    ..To our knowledge, this is the first known reported case of amyloidoma occurring in this location. Solitary amyloidoma of the spine is a rare entity typically manifesting as an extradural tumor with bony involvement. ..
  30. pmc Comparative genomic hybridization in a case of melanoma that loses expression of S100, HMB45, Melan A and tyrosinase in metastasis
    Ruifeng Guo
    Department of Pathology, University of Oklahoma Health Sciences Center Oklahoma City, OK, USA
    Int J Clin Exp Pathol 7:468-73. 2014
    ....
  31. ncbi request reprint Human telomerase reverse transcriptase mRNA is highly expressed in normal breast tissues and down-regulated in ductal carcinoma in situ
    Jinsong Liu
    Department of Pathology, Division of Pathology and Laboratory Medicine, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Int J Oncol 24:879-84. 2004
    ....
  32. ncbi request reprint Cerebellar central liponeurocytoma
    Kar Ming Fung
    Department of Pathology, University of Oklahoma Health Science Center, Oklahoma City, Oklahoma, USA
    Ultrastruct Pathol 27:109-14. 2003
    ..The authors describe a case with clinical, imaging, histological, immunohistochemical, and ultrastructural features...
  33. pmc Glioblastoma with PNET-like components has a higher frequency of isocitrate dehydrogenase 1 (IDH1) mutation and likely a better prognosis than primary glioblastoma
    Xianyuan Song
    Department of Pathology, Hartford Hospital, CT, USA
    Int J Clin Exp Pathol 4:651-60. 2011
    ..Compared to primary GBMs, GBM-PNETs might have a better prognosis. Further large scale studies are necessary to confirm this observation...
  34. pmc Boswellia sacra essential oil induces tumor cell-specific apoptosis and suppresses tumor aggressiveness in cultured human breast cancer cells
    Mahmoud M Suhail
    Al Afia Medical Complex, Salalah, Sultanate of Oman
    BMC Complement Altern Med 11:129. 2011
    ....
  35. doi request reprint Optical coherence tomography as an adjunct to flexible bronchoscopy in the diagnosis of lung cancer: a pilot study
    Ross G Michel
    Division of Pulmonary Critical Care Medicine, Oklahoma City Veterans Affairs Medical Center and University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104 5020, USA
    Chest 138:984-8. 2010
    ..This technology may in the future provide a noninvasive "optical biopsy," which could potentially guide the bronchoscopist to areas for biopsy or even obviate the need for conventional lung biopsies...
  36. ncbi request reprint Amyloid-beta reduction by memapsin 2 (beta-secretase) immunization
    Wan Pin Chang
    Protein Studies Program, Oklahoma Medical Research Foundation, 825 N E 13th St, Oklahoma City, OK 73104, USA
    FASEB J 21:3184-96. 2007
    ..These results suggest that memapsin 2 immunization in Tg2576 was effective in reducing Abeta production and improving cognitive function and that the current approach warrants further investigation as a therapy for AD...
  37. ncbi request reprint Expression of alpha-, beta-, and gamma-synuclein in glial tumors and medulloblastomas
    Kar Ming Fung
    Department of Pathology, University of Oklahoma Health Science Center OUHSC, Rm 451, 940 Stanton L Young Blvd, Oklahoma City, OK 73104, USA
    Acta Neuropathol 106:167-75. 2003
    ..Of medulloblastomas, 76% have immunoreactivity for either alpha- or beta-synuclein or both; no immunoreactivity for gamma-synuclein is seen in medulloblastomas...