Jessica M Fuller

Summary

Affiliation: University of Washington
Country: USA

Publications

  1. pmc Sequence variation and expression of the Gimap gene family in the BB rat
    Elizabeth A Rutledge
    Diabetes and Endocrinology Research Center, University of Washington, Seattle, WA 98109, USA
    Exp Diabetes Res 2009:835650. 2009
  2. pmc Genetic dissection reveals diabetes loci proximal to the gimap5 lymphopenia gene
    J M Fuller
    Department of Clinical Sciences, Lund University, Clinical Research Center, Malmo, Sweden
    Physiol Genomics 38:89-97. 2009
  3. ncbi request reprint Introgression of F344 rat genomic DNA on BB rat chromosome 4 generates diabetes-resistant lymphopenic BB rats
    Jessica M Fuller
    University of Washington, Department of Medicine, 1959 NE Pacific St, Box 357710, Seattle, WA 98195, USA
    Diabetes 55:3351-7. 2006
  4. pmc Differential effects of leptin receptor mutation on male and female BBDR Gimap5-/Gimap5- spontaneously diabetic rats
    Daniel H Moralejo
    Departments of Comparative Medicine, University of Washington, Seattle, Washington 98195, USA
    Physiol Genomics 41:9-20. 2010
  5. pmc BB rat Gimap gene expression in sorted lymphoid T and B cells
    Daniel H Moralejo
    Department of Comparative Medicine, University of Washington 1959 N E Pacific St, Box 357710, Seattle, WA 98195, USA
    Life Sci 89:748-54. 2011
  6. pmc Prolonged survival and improved glycemia in BioBreeding diabetic rats after early sustained exposure to glucagon-like peptide 1
    Ofer Yanay
    Department of Pediatrics, University of Washington, Seattle, WA, USA
    J Gene Med 12:538-44. 2010
  7. ncbi request reprint Decreased core temperature and increased beta(3)-adrenergic sensitivity in diabetes-prone BB rats
    Lina Akesson
    Diabetes and Celiac Disease Unit, Department of Clinical Sciences, Lund University, Malmo, Sweden
    Diabetes Technol Ther 9:354-62. 2007
  8. doi request reprint Analysis of the rat Iddm14 diabetes susceptibility locus in multiple rat strains: identification of a susceptibility haplotype in the Tcrb-V locus
    John P Mordes
    Department of Medicine, University of Massachusetts Medical School, Worcester, MA, 01655, USA
    Mamm Genome 20:162-9. 2009
  9. doi request reprint Treatment of diabetic rats with encapsulated islets
    Ian R Sweet
    Department of Medicine, University of Washington, Seattle, WA 98195, USA
    J Cell Mol Med 12:2644-50. 2008
  10. ncbi request reprint Transgenic rescue demonstrates involvement of the Ian5 gene in T cell development in the rat
    Mieczyslaw Michalkiewicz
    Department of Physiology, Human Molecular and Genetics Center, Medical College of Wisconsin, Milwaukee, Wisconsin 53226 0509, USA
    Physiol Genomics 19:228-32. 2004

Collaborators

  • Anne E Kwitek
  • A Lernmark
  • Elizabeth P Blankenhorn
  • MARTIN JOHN HESSNER
  • I R Sweet
  • Norman Breslow
  • Tyson Hawkins
  • Daniel H Moralejo
  • Richard Jensen
  • Brian Van Yserloo
  • Elizabeth A Rutledge
  • Ruth A Ettinger
  • William Osborne
  • Ofer Yanay
  • John P Mordes
  • Lina Akesson
  • Mieczyslaw Michalkiewicz
  • Carl T Hansen
  • WILLIAM R OSBORNE
  • Randall W Barton
  • Kelly Kernan
  • Margaret Brzezinski
  • Daniel Moralejo
  • Piper Treuting
  • Prashant Gaur
  • Morgan R Peterson
  • Jean Leif
  • Dale L Greiner
  • Jana L Hoehna
  • Laura Cort
  • Elaine Norowski
  • Howard J Jacob
  • Armand J MacMurray
  • Eric S Lander
  • Teresa Michalkiewicz

Detail Information

Publications10

  1. pmc Sequence variation and expression of the Gimap gene family in the BB rat
    Elizabeth A Rutledge
    Diabetes and Endocrinology Research Center, University of Washington, Seattle, WA 98109, USA
    Exp Diabetes Res 2009:835650. 2009
    ..Only four; Gimap1, Gimap4, Gimap5, and Gimap9 were reduced in thymus. Our data substantiates the Gimap5 frameshift mutation as the primary defect with only limited contributions to lymphopenia from the remaining Gimap genes...
  2. pmc Genetic dissection reveals diabetes loci proximal to the gimap5 lymphopenia gene
    J M Fuller
    Department of Clinical Sciences, Lund University, Clinical Research Center, Malmo, Sweden
    Physiol Genomics 38:89-97. 2009
    ..Our results show that spontaneous T1D is controlled by at least two genetic loci 7 Mb apart on rat chromosome 4...
  3. ncbi request reprint Introgression of F344 rat genomic DNA on BB rat chromosome 4 generates diabetes-resistant lymphopenic BB rats
    Jessica M Fuller
    University of Washington, Department of Medicine, 1959 NE Pacific St, Box 357710, Seattle, WA 98195, USA
    Diabetes 55:3351-7. 2006
    ..Spontaneous diabetes in the BB rat may therefore be controlled, in part, by a diabetogenic factor(s), perhaps unrelated to the Gimap5 mutation on rat chromosome 4...
  4. pmc Differential effects of leptin receptor mutation on male and female BBDR Gimap5-/Gimap5- spontaneously diabetic rats
    Daniel H Moralejo
    Departments of Comparative Medicine, University of Washington, Seattle, Washington 98195, USA
    Physiol Genomics 41:9-20. 2010
    ..lepr-/lepr-,Gimap5-/Gimap5-) congenic rats. BBDR.(lepr-/lepr-,Gimap5-/Gimap5-) congenic rats should prove valuable to study interactions between lack of leptin receptor signaling, obesity, and sex-specific T2D and T1D...
  5. pmc BB rat Gimap gene expression in sorted lymphoid T and B cells
    Daniel H Moralejo
    Department of Comparative Medicine, University of Washington 1959 N E Pacific St, Box 357710, Seattle, WA 98195, USA
    Life Sci 89:748-54. 2011
    ..We hypothesized that expression of the Gimap family members within the Iddm39 QTL, during thymocyte development as well as in peripheral T and B cells contribute to T1D...
  6. pmc Prolonged survival and improved glycemia in BioBreeding diabetic rats after early sustained exposure to glucagon-like peptide 1
    Ofer Yanay
    Department of Pediatrics, University of Washington, Seattle, WA, USA
    J Gene Med 12:538-44. 2010
    ..We hypothesized that the expression of GLP-1 before disease onset would increase islet mass, delay diabetes and prolong survival of BB rats...
  7. ncbi request reprint Decreased core temperature and increased beta(3)-adrenergic sensitivity in diabetes-prone BB rats
    Lina Akesson
    Diabetes and Celiac Disease Unit, Department of Clinical Sciences, Lund University, Malmo, Sweden
    Diabetes Technol Ther 9:354-62. 2007
    ..We tested the hypothesis that temperature measurements could serve as a physiological marker for the impending onset of hyperglycemia...
  8. doi request reprint Analysis of the rat Iddm14 diabetes susceptibility locus in multiple rat strains: identification of a susceptibility haplotype in the Tcrb-V locus
    John P Mordes
    Department of Medicine, University of Massachusetts Medical School, Worcester, MA, 01655, USA
    Mamm Genome 20:162-9. 2009
    ....
  9. doi request reprint Treatment of diabetic rats with encapsulated islets
    Ian R Sweet
    Department of Medicine, University of Washington, Seattle, WA 98195, USA
    J Cell Mol Med 12:2644-50. 2008
    ..TheraCyte devices can sustain islets, protect allogeneic cells from immune attack and provide treatment for diabetic-mediated weight loss in both BB rats and STZ-induced diabetic rats...
  10. ncbi request reprint Transgenic rescue demonstrates involvement of the Ian5 gene in T cell development in the rat
    Mieczyslaw Michalkiewicz
    Department of Physiology, Human Molecular and Genetics Center, Medical College of Wisconsin, Milwaukee, Wisconsin 53226 0509, USA
    Physiol Genomics 19:228-32. 2004
    ..It also demonstrates that transgenic rescue in the rat is a practical and definitive method for revealing the function of a novel gene...