D D Fuller

Summary

Affiliation: University of Wisconsin
Country: USA

Publications

  1. ncbi request reprint Fatiguing contractions of tongue protrudor and retractor muscles: influence of systemic hypoxia
    D D Fuller
    Respiratory Physiology Laboratory, Department of Physiology, University of Arizona, Tucson 85719, USA
    J Appl Physiol 88:2123-30. 2000
  2. ncbi request reprint Synaptic pathways to phrenic motoneurons are enhanced by chronic intermittent hypoxia after cervical spinal cord injury
    David D Fuller
    Department of Comparative Biosciences, University of Wisconsin, Madison, Wisconsin 53706, USA
    J Neurosci 23:2993-3000. 2003
  3. pmc Life-long impairment of hypoxic phrenic responses in rats following 1 month of developmental hyperoxia
    D D Fuller
    Department of Comparative Biosciences, University of Wisconsin, 2015 Linden Drive West, Madison, WI 53076, USA
    J Physiol 538:947-55. 2002
  4. pmc Induced recovery of hypoxic phrenic responses in adult rats exposed to hyperoxia for the first month of life
    D D Fuller
    Department of Comparative Biosciences, University of Wisconsin, 2015 Linden Drive West, Madison, WI 53076, USA
    J Physiol 536:917-26. 2001
  5. ncbi request reprint Chronic cervical spinal sensory denervation reveals ineffective spinal pathways to phrenic motoneurons in the rat
    David D Fuller
    Department of Comparative Biosciences, School of Veterinary Medicine, University of Wisconsin, 2015 Linden Drive West, Madison, WI 53706, USA
    Neurosci Lett 323:25-8. 2002
  6. ncbi request reprint Phrenic long-term facilitation requires 5-HT receptor activation during but not following episodic hypoxia
    D D Fuller
    Department of Comparative Biosciences, School of Veterinary Medicine, University of Wisconsin, Madison 53706, USA
    J Appl Physiol 90:2001-6; discussion 2000. 2001
  7. ncbi request reprint Expression of hypoglossal long-term facilitation differs between substrains of Sprague-Dawley rat
    D D Fuller
    Department of Comparative Biosciences, University of Wisconsin, Madison, Wisconsin 53706, USA
    Physiol Genomics 4:175-81. 2001
  8. ncbi request reprint Chronic intermittent hypoxia elicits serotonin-dependent plasticity in the central neural control of breathing
    L Ling
    Departments of Comparative Biosciences and Preventive Medicine, University of Wisconsin, Madison, Wisconsin 53706, USA
    J Neurosci 21:5381-8. 2001
  9. ncbi request reprint Adult carotid chemoafferent responses to hypoxia after 1, 2, and 4 wk of postnatal hyperoxia
    G E Bisgard
    Department of Comparative Biosciences, University of Wisconsin Madison, Madison, WI 53706, USA
    J Appl Physiol 95:946-52. 2003
  10. pmc Developmental plasticity of the hypoxic ventilatory response in rats induced by neonatal hypoxia
    R W Bavis
    Department of Comparative Biosciences, University of Wisconsin, Madison, WI 53706, USA
    J Physiol 557:645-60. 2004

Collaborators

Detail Information

Publications28

  1. ncbi request reprint Fatiguing contractions of tongue protrudor and retractor muscles: influence of systemic hypoxia
    D D Fuller
    Respiratory Physiology Laboratory, Department of Physiology, University of Arizona, Tucson 85719, USA
    J Appl Physiol 88:2123-30. 2000
    ..05). We conclude that hypoxia attenuates tongue protrudor and retractor muscle endurance performance; potential mechanisms include neuromuscular transmission failure and/or diminished sarcolemmal excitability...
  2. ncbi request reprint Synaptic pathways to phrenic motoneurons are enhanced by chronic intermittent hypoxia after cervical spinal cord injury
    David D Fuller
    Department of Comparative Biosciences, University of Wisconsin, Madison, Wisconsin 53706, USA
    J Neurosci 23:2993-3000. 2003
    ..05). We conclude that CIH induced spinal cord plasticity-enhanced phrenic motor output. This plasticity required preconditions established by chronic spinal injury...
  3. pmc Life-long impairment of hypoxic phrenic responses in rats following 1 month of developmental hyperoxia
    D D Fuller
    Department of Comparative Biosciences, University of Wisconsin, 2015 Linden Drive West, Madison, WI 53076, USA
    J Physiol 538:947-55. 2002
    ..4 (+/- 1.6) x 10(6) microm3; P <0.01). We conclude that exposure to hyperoxia for the first month of life causes life-long impairment of carotid chemoreceptor function and, consequently, blunted phrenic responses to hypoxia...
  4. pmc Induced recovery of hypoxic phrenic responses in adult rats exposed to hyperoxia for the first month of life
    D D Fuller
    Department of Comparative Biosciences, University of Wisconsin, 2015 Linden Drive West, Madison, WI 53076, USA
    J Physiol 536:917-26. 2001
    ....
  5. ncbi request reprint Chronic cervical spinal sensory denervation reveals ineffective spinal pathways to phrenic motoneurons in the rat
    David D Fuller
    Department of Comparative Biosciences, School of Veterinary Medicine, University of Wisconsin, 2015 Linden Drive West, Madison, WI 53706, USA
    Neurosci Lett 323:25-8. 2002
    ..v.) had no effect on the crossed phrenic potential amplitude (91+/-17% of control at 800 microA; P>0.05). Thus, CDR enhances crossed phrenic pathways but serotonin receptor activation is not necessary to maintain this effect...
  6. ncbi request reprint Phrenic long-term facilitation requires 5-HT receptor activation during but not following episodic hypoxia
    D D Fuller
    Department of Comparative Biosciences, School of Veterinary Medicine, University of Wisconsin, Madison 53706, USA
    J Appl Physiol 90:2001-6; discussion 2000. 2001
    ..Conversely, ketanserin pretreatment abolished phrenic LTF. We conclude that 5-HT receptor activation is necessary to initiate (during hypoxia) but not maintain (following hypoxia) phrenic LTF...
  7. ncbi request reprint Expression of hypoglossal long-term facilitation differs between substrains of Sprague-Dawley rat
    D D Fuller
    Department of Comparative Biosciences, University of Wisconsin, Madison, Wisconsin 53706, USA
    Physiol Genomics 4:175-81. 2001
    ..We conclude that the expression of hypoglossal LTF differs between SD rat substrains, indicating a difference in their genetic predisposition to neural plasticity...
  8. ncbi request reprint Chronic intermittent hypoxia elicits serotonin-dependent plasticity in the central neural control of breathing
    L Ling
    Departments of Comparative Biosciences and Preventive Medicine, University of Wisconsin, Madison, Wisconsin 53706, USA
    J Neurosci 21:5381-8. 2001
    ..The results suggest that CIH elicits unique forms of serotonin-dependent plasticity in the central neural control of breathing. Enhanced LTF after CIH may involve an upregulation of a non-5-HT(2) serotonin receptor subtype or subtypes...
  9. ncbi request reprint Adult carotid chemoafferent responses to hypoxia after 1, 2, and 4 wk of postnatal hyperoxia
    G E Bisgard
    Department of Comparative Biosciences, University of Wisconsin Madison, Madison, WI 53706, USA
    J Appl Physiol 95:946-52. 2003
    ..These studies illustrate the importance of normoxia during the first 2 wk of life in development of carotid chemoreceptor afferent function...
  10. pmc Developmental plasticity of the hypoxic ventilatory response in rats induced by neonatal hypoxia
    R W Bavis
    Department of Comparative Biosciences, University of Wisconsin, Madison, WI 53706, USA
    J Physiol 557:645-60. 2004
    ..The basis of sex differences in this developmental plasticity is unknown...
  11. ncbi request reprint Invited review: Intermittent hypoxia and respiratory plasticity
    G S Mitchell
    Department of Comparative Biosciences, University of Wisconsin, Madison, Wisconsin 53706, USA
    J Appl Physiol 90:2466-75. 2001
    ....
  12. ncbi request reprint Long term facilitation of phrenic motor output
    D D Fuller
    Department of Comparative Biosciences, University of Wisconsin, 2015 Linden Drive West, Madison, WI 53706, USA
    Respir Physiol 121:135-46. 2000
    ....
  13. ncbi request reprint Respiratory plasticity: differential actions of continuous and episodic hypoxia and hypercapnia
    T L Baker
    Center for Neuroscience, University of Wisconsin, 2015 Linden Drive West, Madison, WI 53706, USA
    Respir Physiol 129:25-35. 2001
    ..We hypothesize that the response of respiratory motoneurons to serotonergic and noradrenergic modulation may contribute to pattern sensitivity to hypoxia and hypercapnia...
  14. pmc Breathing patterns after mid-cervical spinal contusion in rats
    F J Golder
    Department of Comparative Biosciences, University of Wisconsin, Madison, WI 53706 1102, USA
    Exp Neurol 231:97-103. 2011
    ....
  15. pmc Effect of pulmonary stretch receptor feedback and CO(2) on upper airway and respiratory pump muscle activity in the rat
    E F Bailey
    Department of Physiology, College of Medicine, The University of Arizona, Tucson, AZ 85721 0093, USA
    J Physiol 532:525-34. 2001
    ..Hypoglossal motoneurons driving tongue protrudor and retractor muscles respond identically to these stimuli...
  16. ncbi request reprint Ventilatory long-term facilitation in unanesthetized rats
    E B Olson
    The John Rankin Laboratory of Pulmonary Medicine, Department of Preventive Medicine, University of Wisconsin School of Medicine, Madison, 53705 2368, USA
    J Appl Physiol 91:709-16. 2001
    ..Ventilatory LTF appeared similar in its magnitude (after accounting for CO(2) feedback), time course, and dependence on intermittent hypoxia to phrenic LTF previously observed in anesthetized, vagotomized, paralyzed rats...
  17. ncbi request reprint Respiratory-related control of extrinsic tongue muscle activity
    R F Fregosi
    Department of Physiology, University of Arizona, Tucson 85721 0093, USA
    Respir Physiol 110:295-306. 1997
    ..The possible mechanical consequences of tongue muscle co-activation are briefly considered...
  18. ncbi request reprint Pulmonary C-fiber receptor activation abolishes uncoupled facial nerve activity from phrenic bursting during positive end-expired pressure in the rat
    Kun Ze Lee
    Dept of Life Science, National Taiwan Normal Univ, Taipei, Taiwan
    J Appl Physiol 104:119-29. 2008
    ..We conclude that activation of PCF receptors can inhibit FN bursting during PEEP-induced phrenic apnea by inhibiting EI and I facial motoneuron discharge...
  19. ncbi request reprint Uncoupling of upper airway motor activity from phrenic bursting by positive end-expired pressure in the rat
    Kun Ze Lee
    Dept of Life Science, National Taiwan Normal University, Taipei, Taiwan
    J Appl Physiol 102:878-89. 2007
    ..The relationship between PEEP and EI motoneuron discharge rate differs during preinspiratory and I periods; this may indicate that bursting during these phases of the respiratory cycle is controlled by distinct neuronal outputs...
  20. ncbi request reprint Neural drive to tongue protrudor and retractor muscles following pulmonary C-fiber activation
    Kun Ze Lee
    Department of Life Science, National Taiwan Normal University, Taipei, Taiwan, ROC
    J Appl Physiol 102:434-44. 2007
    ..Accordingly, reductions in upper airway stiffness associated with reduced XII burst amplitude may be offset by enhanced tonic activity in tongue protrudor muscles...
  21. ncbi request reprint Respiratory motor recovery after unilateral spinal cord injury: eliminating crossed phrenic activity decreases tidal volume and increases contralateral respiratory motor output
    Francis J Golder
    Department of Physiological Sciences, College of Veterinary Medicine, University of Florida, Gainesville, Florida 32610, USA
    J Neurosci 23:2494-501. 2003
    ..Moreover, by preventing ipsilateral phrenic motor recovery in rats with unilateral SCI, segmental and supraspinal changes could be induced in contralateral respiratory motor output beyond that seen with SCI alone...
  22. ncbi request reprint Recovery of phrenic activity and ventilation after cervical spinal hemisection in rats
    David D Fuller
    Dept of Comparative Biosciences, School of Veterinary Medicine, University of Wisconsin, Madison, USA
    J Appl Physiol 100:800-6. 2006
    ..Enhanced crossed phrenic activity post-C2HS may reflect plasticity associated with spinal axons not activated by our ventrolateral spinal stimulation...
  23. ncbi request reprint Cervical spinal cord injury upregulates ventral spinal 5-HT2A receptors
    David D Fuller
    Department of Comparative Biosciences, School of Veterinary Medicine, University of Wisconsin, Madison, Wisconsin, USA
    J Neurotrauma 22:203-13. 2005
    ..05). Our data are consistent with the hypothesis that spontaneous increase in 5-HT2A receptor expression on or near phrenic motoneurons contributes to strengthened crossed-spinal synaptic pathways to phrenic motoneurons following C2HS...
  24. ncbi request reprint Differences in time-dependent hypoxic phrenic responses among inbred rat strains
    Francis J Golder
    Department of Comparative Bioscience, University of Wisconsin, Madison, Wisconsin, USA
    J Appl Physiol 98:838-44. 2005
    ..Furthermore, genetic diversity observed in hypoxic ventilatory responses in unanesthetized rats may arise from multiple neural mechanisms...
  25. ncbi request reprint BDNF is necessary and sufficient for spinal respiratory plasticity following intermittent hypoxia
    Tracy L Baker-Herman
    Department of Comparative Biosciences, University of Wisconsin, Madison, Wisconsin 53706, USA
    Nat Neurosci 7:48-55. 2004
    ..These experiments also illustrate the potential use of RNAi to investigate functional consequences of gene expression in the mammalian nervous system in vivo...
  26. pmc Respiratory-related activation of human abdominal muscles during exercise
    Kirk A Abraham
    Department of Physiology, The University of Arizona Health Sciences Center, Tucson, AZ 85721, USA
    J Physiol 541:653-63. 2002
    ..The contribution of abdominal muscles to ventilation during constant work rate exercise is variable, and expiratory activity does not 'drift' significantly with time...
  27. ncbi request reprint Physiological correction of Pompe disease by systemic delivery of adeno-associated virus serotype 1 vectors
    Cathryn Mah
    Powell Gene Therapy Center, University of Florida, Gainesville, Florida, USA
    Mol Ther 15:501-7. 2007
    ....
  28. pmc Neurogenesis of cough, other airway defensive behaviors and breathing: A holarchical system?
    Donald C Bolser
    Department of Physiological Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL, USA
    Respir Physiol Neurobiol 152:255-65. 2006
    ..As such, co-expression of multiple rhythmic behaviors such as cough and swallow can occur without compromising airway defense...