Sabine Fuhrmann

Summary

Affiliation: University of Utah
Country: USA

Publications

  1. pmc Characterization of a transient TCF/LEF-responsive progenitor population in the embryonic mouse retina
    Sabine Fuhrmann
    Department of Ophthalmology and Visual Sciences, Moran Eye Center, University of Utah, Salt Lake City, Utah 84132, USA
    Invest Ophthalmol Vis Sci 50:432-40. 2009
  2. pmc A nonautonomous role for retinal frizzled-5 in regulating hyaloid vitreous vasculature development
    Jianmin Zhang
    Department of Neurobiology and Anatomy, Moran Eye Center, University of Utah, Salt Lake City, USA
    Invest Ophthalmol Vis Sci 49:5561-7. 2008
  3. pmc Extraocular ectoderm triggers dorsal retinal fate during optic vesicle evagination in zebrafish
    Renee Kruse-Bend
    Department of Neurobiology and Anatomy, 20 North 1900 East, Room 401 MREB, University of Utah, Salt Lake City, UT 84132, USA
    Dev Biol 371:57-65. 2012
  4. pmc Ectopic Mitf in the embryonic chick retina by co-transfection of β-catenin and Otx2
    Peter D Westenskow
    Department of Ophthalmology and Visual Sciences, Moran Eye Center, University of Utah, Salt Lake City, Utah 84132, USA
    Invest Ophthalmol Vis Sci 51:5328-35. 2010
  5. pmc Beta-catenin controls differentiation of the retinal pigment epithelium in the mouse optic cup by regulating Mitf and Otx2 expression
    Peter Westenskow
    Department of Ophthalmology and Visual Sciences, Moran Eye Center, University of Utah, Salt Lake City, UT 84132, USA
    Development 136:2505-10. 2009
  6. ncbi request reprint Expression of Frizzled genes in the developing chick eye
    Sabine Fuhrmann
    Department of Ophthalmology and Visual Sciences, Eccles Institute of Human Genetics, University of Utah, 15 North 2030 East, Salt Lake City, UT 84112, USA
    Gene Expr Patterns 3:659-62. 2003
  7. ncbi request reprint Distribution of CNTF receptor alpha protein in the central nervous system of the chick embryo
    Sabine Fuhrmann
    Department of Ophthalmology and Visual Sciences, Eccles Institute of Human Genetics, University of Utah, Salt Lake City, Utah 84112, USA
    J Comp Neurol 461:111-22. 2003
  8. pmc Investigation of Frizzled-5 during embryonic neural development in mouse
    Carole J Burns
    Department of Neurobiology and Anatomy, John A Moran Eye Center, University of Utah, Salt Lake City, Utah 84132, USA
    Dev Dyn 237:1614-26. 2008
  9. pmc Eye morphogenesis and patterning of the optic vesicle
    Sabine Fuhrmann
    Department of Ophthalmology and Visual Sciences, Moran Eye Center, University of Utah, Salt Lake City, Utah, USA
    Curr Top Dev Biol 93:61-84. 2010
  10. ncbi request reprint Expression of CNTF receptor-alpha in chick violet-sensitive cones with unique morphologic properties
    Vera Seydewitz
    Institute of Anatomy and Cell Biology, University of Freiburg, Freiburg, Germany
    Invest Ophthalmol Vis Sci 45:655-61. 2004

Research Grants

  1. Mechanisms Controlling RPE Development
    Sabine Fuhrmann; Fiscal Year: 2010
  2. Patterning of the optic vesicle by extrinsic factors
    Sabine Fuhrmann; Fiscal Year: 2003
  3. Role of Wnt/Frizzled signaling during eye development
    Sabine Fuhrmann; Fiscal Year: 2007

Collaborators

Detail Information

Publications10

  1. pmc Characterization of a transient TCF/LEF-responsive progenitor population in the embryonic mouse retina
    Sabine Fuhrmann
    Department of Ophthalmology and Visual Sciences, Moran Eye Center, University of Utah, Salt Lake City, Utah 84132, USA
    Invest Ophthalmol Vis Sci 50:432-40. 2009
    ..The goal of the study was to characterize more fully a TCF/LEF-responsive retinal progenitor population in the mouse embryo and to correlate this with Wnt/beta-catenin signaling...
  2. pmc A nonautonomous role for retinal frizzled-5 in regulating hyaloid vitreous vasculature development
    Jianmin Zhang
    Department of Neurobiology and Anatomy, Moran Eye Center, University of Utah, Salt Lake City, USA
    Invest Ophthalmol Vis Sci 49:5561-7. 2008
    ..The present study analyzed the effects of tissue-specific deletion of Fzd5 on mammalian eye development...
  3. pmc Extraocular ectoderm triggers dorsal retinal fate during optic vesicle evagination in zebrafish
    Renee Kruse-Bend
    Department of Neurobiology and Anatomy, 20 North 1900 East, Room 401 MREB, University of Utah, Salt Lake City, UT 84132, USA
    Dev Biol 371:57-65. 2012
    ..We find that bmp2b is involved in dorsal retina initiation, acting upstream of gdf6a. Together, this work has identified the nature and source of extraocular signals required to pattern the dorsal retina...
  4. pmc Ectopic Mitf in the embryonic chick retina by co-transfection of β-catenin and Otx2
    Peter D Westenskow
    Department of Ophthalmology and Visual Sciences, Moran Eye Center, University of Utah, Salt Lake City, Utah 84132, USA
    Invest Ophthalmol Vis Sci 51:5328-35. 2010
    ..The study was conducted to determine whether Otx2 and β-catenin act in a combinatorial manner and tested whether co-expression in the presumptive chick retina induces ectopic Mitf expression...
  5. pmc Beta-catenin controls differentiation of the retinal pigment epithelium in the mouse optic cup by regulating Mitf and Otx2 expression
    Peter Westenskow
    Department of Ophthalmology and Visual Sciences, Moran Eye Center, University of Utah, Salt Lake City, UT 84132, USA
    Development 136:2505-10. 2009
    ....
  6. ncbi request reprint Expression of Frizzled genes in the developing chick eye
    Sabine Fuhrmann
    Department of Ophthalmology and Visual Sciences, Eccles Institute of Human Genetics, University of Utah, 15 North 2030 East, Salt Lake City, UT 84112, USA
    Gene Expr Patterns 3:659-62. 2003
    ..Frizzled-1 to -9 are specifically expressed in the eye at various stages of development and show a complex and partially overlapping pattern of expression...
  7. ncbi request reprint Distribution of CNTF receptor alpha protein in the central nervous system of the chick embryo
    Sabine Fuhrmann
    Department of Ophthalmology and Visual Sciences, Eccles Institute of Human Genetics, University of Utah, Salt Lake City, Utah 84112, USA
    J Comp Neurol 461:111-22. 2003
    ..These results suggest that the CNTF receptor performs distinct developmental functions in different animals...
  8. pmc Investigation of Frizzled-5 during embryonic neural development in mouse
    Carole J Burns
    Department of Neurobiology and Anatomy, John A Moran Eye Center, University of Utah, Salt Lake City, Utah 84132, USA
    Dev Dyn 237:1614-26. 2008
    ..Thus, the function of Fzd5 during eye development appears to be species-dependent...
  9. pmc Eye morphogenesis and patterning of the optic vesicle
    Sabine Fuhrmann
    Department of Ophthalmology and Visual Sciences, Moran Eye Center, University of Utah, Salt Lake City, Utah, USA
    Curr Top Dev Biol 93:61-84. 2010
    ....
  10. ncbi request reprint Expression of CNTF receptor-alpha in chick violet-sensitive cones with unique morphologic properties
    Vera Seydewitz
    Institute of Anatomy and Cell Biology, University of Freiburg, Freiburg, Germany
    Invest Ophthalmol Vis Sci 45:655-61. 2004
    ..The present study was undertaken to identify the CNTF receptor-expressing photoreceptors and to describe the subcellular localization of the receptor protein...

Research Grants8

  1. Mechanisms Controlling RPE Development
    Sabine Fuhrmann; Fiscal Year: 2010
    ..Together, the goal of experiments proposed here will advance our understanding of the signals that control RPE development and may provide clues for new putative targets for therapeutic treatment of degenerative diseases in the eye. ..
  2. Patterning of the optic vesicle by extrinsic factors
    Sabine Fuhrmann; Fiscal Year: 2003
    ..Subsequently, the identified molecule will be cloned and tested for the RPE-promoting activity in explant cultures and by transfection of chick embryos. ..
  3. Role of Wnt/Frizzled signaling during eye development
    Sabine Fuhrmann; Fiscal Year: 2007
    ..In addition, these studies should provide more general insight into the role of Wnt/beta-catenin signaling during nervous system development. ..