Liang Wu Fu

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Functional role of peripheral opioid receptors in the regulation of cardiac spinal afferent nerve activity during myocardial ischemia
    Liang Wu Fu
    Department of Medicine, School of Medicine, University of California, Irvine, CA 92697, USA
    Am J Physiol Heart Circ Physiol 305:H76-85. 2013
  2. pmc Ionotropic glutamate receptors in the external lateral parabrachial nucleus participate in processing cardiac sympathoexcitatory reflexes
    Liang Wu Fu
    Department of Medicine, College of Medicine, University of California, Irvine, 92697, USA
    Am J Physiol Heart Circ Physiol 302:H1444-53. 2012
  3. pmc A new function for ATP: activating cardiac sympathetic afferents during myocardial ischemia
    Liang Wu Fu
    Department of Medicine, School of Medicine, University of California, Irvine, Irvine, California, USA
    Am J Physiol Heart Circ Physiol 299:H1762-71. 2010
  4. pmc Endogenous endothelin stimulates cardiac sympathetic afferents during ischaemia
    Liang Wu Fu
    Department of Medicine, School of Medicine, University of California, Irvine, CA 92697, USA
    J Physiol 588:2473-86. 2010
  5. pmc Bradykinin and thromboxane A2 reciprocally interact to synergistically stimulate cardiac spinal afferents during myocardial ischemia
    Liang Wu Fu
    Department of Medicine, School of Medicine, University of California, Irvine, CA 92697, USA
    Am J Physiol Heart Circ Physiol 298:H235-44. 2010
  6. pmc Electroacupuncture modulates vlPAG release of GABA through presynaptic cannabinoid CB1 receptors
    Liang Wu Fu
    Department of Medicine, University of California, Irvine, CA 92697, USA
    J Appl Physiol 106:1800-9. 2009
  7. pmc Myocardial ischemia-mediated excitatory reflexes: a new function for thromboxane A2?
    Liang Wu Fu
    Department of Medicine, Susan Samueli Center for Integrative Medicine, School of Mediicne, University of California, Irvine, Irvine, CA 92697, USA
    Am J Physiol Heart Circ Physiol 295:H2530-40. 2008
  8. pmc Undiscovered role of endogenous thromboxane A2 in activation of cardiac sympathetic afferents during ischaemia
    Liang Wu Fu
    Department of Medicine, School of Medicine, University of California, Irvine, Irvine, CA 92697, USA
    J Physiol 586:3287-300. 2008
  9. pmc Activated platelets contribute to stimulation of cardiac afferents during ischaemia in cats: role of 5-HT(3) receptors
    Liang Wu Fu
    Department of Medicine, University of California, Irvine 92697, USA
    J Physiol 544:897-912. 2002
  10. ncbi request reprint Histamine contributes to ischemia-related activation of cardiac spinal afferents: role of H1 receptors and PKC
    Liang Wu Fu
    Department of Medicine, C240 Medical Sciences I, University of California, Irvine, Irvine, CA 92697, USA
    J Neurophysiol 93:713-22. 2005

Detail Information

Publications19

  1. pmc Functional role of peripheral opioid receptors in the regulation of cardiac spinal afferent nerve activity during myocardial ischemia
    Liang Wu Fu
    Department of Medicine, School of Medicine, University of California, Irvine, CA 92697, USA
    Am J Physiol Heart Circ Physiol 305:H76-85. 2013
    ..These data suggest that peripheral opioid peptides suppress the responses of cardiac sympathetic afferent nerves to myocardial ischemia and ischemic mediators like ATP and bradykinin...
  2. pmc Ionotropic glutamate receptors in the external lateral parabrachial nucleus participate in processing cardiac sympathoexcitatory reflexes
    Liang Wu Fu
    Department of Medicine, College of Medicine, University of California, Irvine, 92697, USA
    Am J Physiol Heart Circ Physiol 302:H1444-53. 2012
    ..These data are the first to show that NMDA and AMPA ionotropic glutamate receptors in the elPBN play an important role in processing cardiac excitatory reflex responses...
  3. pmc A new function for ATP: activating cardiac sympathetic afferents during myocardial ischemia
    Liang Wu Fu
    Department of Medicine, School of Medicine, University of California, Irvine, Irvine, California, USA
    Am J Physiol Heart Circ Physiol 299:H1762-71. 2010
    ....
  4. pmc Endogenous endothelin stimulates cardiac sympathetic afferents during ischaemia
    Liang Wu Fu
    Department of Medicine, School of Medicine, University of California, Irvine, CA 92697, USA
    J Physiol 588:2473-86. 2010
    ....
  5. pmc Bradykinin and thromboxane A2 reciprocally interact to synergistically stimulate cardiac spinal afferents during myocardial ischemia
    Liang Wu Fu
    Department of Medicine, School of Medicine, University of California, Irvine, CA 92697, USA
    Am J Physiol Heart Circ Physiol 298:H235-44. 2010
    ....
  6. pmc Electroacupuncture modulates vlPAG release of GABA through presynaptic cannabinoid CB1 receptors
    Liang Wu Fu
    Department of Medicine, University of California, Irvine, CA 92697, USA
    J Appl Physiol 106:1800-9. 2009
    ..33.8 +/- 8.7 nM, Glu vs. GABA). These results suggest that EA modulates the sympathoexcitatory reflex responses by decreasing the release of GABA, but not Glu, in the vlPAG, most likely through a presynaptic CB(1) receptor mechanism...
  7. pmc Myocardial ischemia-mediated excitatory reflexes: a new function for thromboxane A2?
    Liang Wu Fu
    Department of Medicine, Susan Samueli Center for Integrative Medicine, School of Mediicne, University of California, Irvine, Irvine, CA 92697, USA
    Am J Physiol Heart Circ Physiol 295:H2530-40. 2008
    ..These data indicate that endogenous TxA2 participates in myocardial ischemia-mediated sympathoexcitatory reflex responses through a TP receptor mechanism...
  8. pmc Undiscovered role of endogenous thromboxane A2 in activation of cardiac sympathetic afferents during ischaemia
    Liang Wu Fu
    Department of Medicine, School of Medicine, University of California, Irvine, Irvine, CA 92697, USA
    J Physiol 586:3287-300. 2008
    ....
  9. pmc Activated platelets contribute to stimulation of cardiac afferents during ischaemia in cats: role of 5-HT(3) receptors
    Liang Wu Fu
    Department of Medicine, University of California, Irvine 92697, USA
    J Physiol 544:897-912. 2002
    ..These data indicate that during myocardial ischaemia the activated platelets stimulate cardiac sympathetic afferents, at least in part, through a 5-HT(3) receptor mechanism...
  10. ncbi request reprint Histamine contributes to ischemia-related activation of cardiac spinal afferents: role of H1 receptors and PKC
    Liang Wu Fu
    Department of Medicine, C240 Medical Sciences I, University of California, Irvine, Irvine, CA 92697, USA
    J Neurophysiol 93:713-22. 2005
    ....
  11. pmc Interactions between histamine and bradykinin in stimulation of ischaemically sensitive cardiac afferents in felines
    Liang Wu Fu
    Department of Medicine, College of Medicine, University of California at Irvine, Irvine, CA 92697, USA
    J Physiol 565:1007-17. 2005
    ..BK sensitizes cardiac afferents responding to histamine in a time-dependent fashion, and the BK sensitization effect is dependent on an intact cyclooxygenase pathway. Conversely, histamine reduces the response of most afferents to BK...
  12. ncbi request reprint Role of activated platelets in excitation of cardiac afferents during myocardial ischemia in cats
    Liang Wu Fu
    Department of Medicine, College of Medicine, C240 Medical Sciences I, University of California, Irvine, CA 92697 4075, USA
    Am J Physiol Heart Circ Physiol 282:H100-9. 2002
    ..These data indicate activated platelets stimulate ischemia-sensitive cardiac spinal afferents and contribute to activation of these afferents during ischemia...
  13. ncbi request reprint Role of glutamate in the rostral ventrolateral medulla in acupuncture-related modulation of visceral reflex sympathoexcitation
    Wei Zhou
    Department of Medicine and Susan Samueli Center for Integrative Medicine, College of Medicine, University of California, Irvine, California 92697 4075, USA
    Am J Physiol Heart Circ Physiol 292:H1868-75. 2007
    ..These data suggest that EA attenuates BK-induced visceral sympathoexcitatory reflexes through opioid-mediated inhibition of Glu's action in the rVLM...
  14. ncbi request reprint Role of glutamate in a visceral sympathoexcitatory reflex in rostral ventrolateral medulla of cats
    Wei Zhou
    Susan Samueli Center for Integrative Medicine, Department of Medicine, School of Medicine, University of California, Irvine, CA 92697 4075, USA
    Am J Physiol Heart Circ Physiol 291:H1309-18. 2006
    ..These results suggest that glutamate in the rVLM serves as an excitatory neurotransmitter through a baroreflex-independent mechanism and that both NMDA and AMPA receptors mediate the visceral sympathoexcitatory reflex responses...
  15. ncbi request reprint Afferent mechanisms underlying stimulation modality-related modulation of acupuncture-related cardiovascular responses
    Wei Zhou
    Department of Medicine, College of Medicine, University of California, Irvine, CA 92697, USA
    J Appl Physiol 98:872-80. 2005
    ..The similarity of the responses to EA and MA and the lack of cardiovascular response to high-frequency EA appear to be largely a function of somatic afferent responses...
  16. pmc Long-loop pathways in cardiovascular electroacupuncture responses
    Peng Li
    Department of Medicine, University of California, Irvine, CA, USA
    J Appl Physiol 106:620-30. 2009
    ..Direct projections from the ARC to the rVLM, which serve as an important source of beta-endorphin, appear also to exist...
  17. pmc Xanthine oxidase, but not neutrophils, contributes to activation of cardiac sympathetic afferents during myocardial ischaemia in cats
    Stephanie C Tjen-A-Looi
    Department of Internal Medicine, College of Medicine, University of California, Irvine, CA 92697 4075, USA
    J Physiol 543:327-36. 2002
    ..This study demonstrates that ROS generated from the oxidation of purines contribute to the stimulation of ischaemically sensitive cardiac sympathetic afferents, whereas PMNs do not play a major role in this process...
  18. pmc Nitric oxide in rostral ventrolateral medulla regulates cardiac-sympathetic reflexes: role of synthase isoforms
    Zhi Ling Guo
    Department of Medicine, School of Medicine, University of California, Susan Samueli Center for Integrative Medicine, Irvine, Irvine, California 92697 4075, USA
    Am J Physiol Heart Circ Physiol 297:H1478-86. 2009
    ..These data suggest that NO, specifically nNOS, mediates sympathetic cardiac-cardiovascular responses through its action in the rVLM...
  19. ncbi request reprint Role of unmyelinated fibers in electroacupuncture cardiovascular responses
    Stephanie C Tjen-A-Looi
    Medical Science 1, Department of Medicine, College of Medicine, University of California, Irvine, CA 92697 4075, USA
    Auton Neurosci 118:43-50. 2005
    ..This study demonstrates that the inhibitory effect of EA at P5-P6 on cardiovascular autonomic excitatory reflexes involves unmyelinated group IV fibers of the median nerves...