Jian Fu

Summary

Affiliation: University of Rochester
Country: USA

Publications

  1. pmc EGLN3 inhibition of NF-κB is mediated by prolyl hydroxylase-independent inhibition of IκB kinase γ ubiquitination
    Jian Fu
    Aab Cardiovascular Research Institute and Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, New York, USA
    Mol Cell Biol 33:3050-61. 2013
  2. ncbi request reprint EGLN3 prolyl hydroxylase regulates skeletal muscle differentiation and myogenin protein stability
    Jian Fu
    Cardiovascular Research Institute and Department of Medicine, Univeristy of Rochester Medical Center, Rochester, NY 14642, USA
    J Biol Chem 282:12410-8. 2007
  3. pmc Prolyl hydroxylase EGLN3 regulates skeletal myoblast differentiation through an NF-kappaB-dependent pathway
    Jian Fu
    Department of Medicine, Aab Cardiovascular Research Institute, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA
    J Biol Chem 285:8927-35. 2010
  4. ncbi request reprint Smac3, a novel Smac/DIABLO splicing variant, attenuates the stability and apoptosis-inhibiting activity of X-linked inhibitor of apoptosis protein
    Jian Fu
    Department of Pathology and Laboratory Medicine, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA
    J Biol Chem 278:52660-72. 2003
  5. ncbi request reprint Chemopreventive agents induce programmed death-1-ligand 1 (PD-L1) surface expression in breast cancer cells and promote PD-L1-mediated T cell apoptosis
    Ping Zhang
    Center for Biomedical Research, University of Texas Health Center at Tyler, Tyler, TX 75708, USA
    Mol Immunol 45:1470-6. 2008

Collaborators

Detail Information

Publications5

  1. pmc EGLN3 inhibition of NF-κB is mediated by prolyl hydroxylase-independent inhibition of IκB kinase γ ubiquitination
    Jian Fu
    Aab Cardiovascular Research Institute and Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, New York, USA
    Mol Cell Biol 33:3050-61. 2013
    ..This study provides novel insights into EGLN3 function and sheds new light on the regulation of IKKγ ubiquitination and NF-κB. ..
  2. ncbi request reprint EGLN3 prolyl hydroxylase regulates skeletal muscle differentiation and myogenin protein stability
    Jian Fu
    Cardiovascular Research Institute and Department of Medicine, Univeristy of Rochester Medical Center, Rochester, NY 14642, USA
    J Biol Chem 282:12410-8. 2007
    ..In addition, this report provides evidence for a novel pathway that regulates myogenin expression and skeletal muscle differentiation...
  3. pmc Prolyl hydroxylase EGLN3 regulates skeletal myoblast differentiation through an NF-kappaB-dependent pathway
    Jian Fu
    Department of Medicine, Aab Cardiovascular Research Institute, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA
    J Biol Chem 285:8927-35. 2010
    ..This study demonstrates a novel role for EGLN3 in the regulation of NF-kappaB and suggests that it is involved in mediating myogenic differentiation, which is HIF-independent...
  4. ncbi request reprint Smac3, a novel Smac/DIABLO splicing variant, attenuates the stability and apoptosis-inhibiting activity of X-linked inhibitor of apoptosis protein
    Jian Fu
    Department of Pathology and Laboratory Medicine, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA
    J Biol Chem 278:52660-72. 2003
    ..Smac3-accelerated XIAP destabilization is, at least in part, attributed to its ability to enhance XIAP ubiquitination. Our study demonstrates that Smac3 is functionally additive to, but independent of, Smac/DIABLO...
  5. ncbi request reprint Chemopreventive agents induce programmed death-1-ligand 1 (PD-L1) surface expression in breast cancer cells and promote PD-L1-mediated T cell apoptosis
    Ping Zhang
    Center for Biomedical Research, University of Texas Health Center at Tyler, Tyler, TX 75708, USA
    Mol Immunol 45:1470-6. 2008
    ..Our studies reveal a potential link between chemotherapy and cancer immunoresistance...