JAMES DUNCAN FRY

Summary

Affiliation: University of Rochester
Country: USA

Publications

  1. pmc The genetic architecture of fitness in a seed beetle: assessing the potential for indirect genetic benefits of female choice
    T Bilde
    Animal Ecology Department of Ecology and Evolution, Evolutionary Biology Centre, University of Uppsala, Uppsala SE 753 32, Sweden
    BMC Evol Biol 8:295. 2008
  2. pmc The genomic location of sexually antagonistic variation: some cautionary comments
    James D Fry
    Department of Biology, University of Rochester, Rochester, New York 14627, USA
    Evolution 64:1510-6. 2010
  3. ncbi request reprint A worldwide polymorphism in aldehyde dehydrogenase in Drosophila melanogaster: evidence for selection mediated by dietary ethanol
    James D Fry
    Department of Biology, University of Rochester, Rochester, NY 14627, USA
    Evolution 62:66-75. 2008
  4. pmc On the rate and linearity of viability declines in Drosophila mutation-accumulation experiments: genomic mutation rates and synergistic epistasis revisited
    James D Fry
    Department of Biology, University of Rochester, Rochester, NY 14627, USA
    Genetics 166:797-806. 2004
  5. ncbi request reprint Genotype-environment interaction for total fitness in Drosophila
    James D Fry
    Department of Biology, University of Rochester, Rochester NY 14627 0211, USA
    J Genet 87:355-62. 2008
  6. ncbi request reprint Multilocus models of sympatric speciation: Bush versus Rice versus Felsenstein
    James D Fry
    Department of Biology, University of Rochester, Rochester, New York 14627 0211, USA
    Evolution 57:1735-46. 2003
  7. pmc Dominance of mutations affecting viability in Drosophila melanogaster
    James D Fry
    Department of Biology, University of Rochester, Rochester, New York 14627, USA
    Genetics 163:1357-64. 2003
  8. pmc Environment dependence of mutational parameters for viability in Drosophila melanogaster
    James D Fry
    Department of Biology, University of Rochester, Rochester, NY 14627 0211, USA
    Genetics 161:1155-67. 2002
  9. ncbi request reprint Rapid mutational declines of viability in Drosophila
    J D Fry
    Department of Biology, University of Rochester, Rochester, NY 14627, USA
    Genet Res 77:53-60. 2001
  10. ncbi request reprint Aldehyde dehydrogenase is essential for both adult and larval ethanol resistance in Drosophila melanogaster
    James D Fry
    Department of Biology, University of Rochester, Rochester, NY 14627, USA
    Genet Res 87:87-92. 2006

Collaborators

Detail Information

Publications14

  1. pmc The genetic architecture of fitness in a seed beetle: assessing the potential for indirect genetic benefits of female choice
    T Bilde
    Animal Ecology Department of Ecology and Evolution, Evolutionary Biology Centre, University of Uppsala, Uppsala SE 753 32, Sweden
    BMC Evol Biol 8:295. 2008
    ..From reciprocal crosses of inbred lines, we assayed egg production, egg-to-adult survival, and lifetime offspring production of the outbred F1 daughters (F1 productivity)...
  2. pmc The genomic location of sexually antagonistic variation: some cautionary comments
    James D Fry
    Department of Biology, University of Rochester, Rochester, New York 14627, USA
    Evolution 64:1510-6. 2010
    ..Although more work is needed to resolve the issue, it is premature to conclude that the X chromosome is a "hot spot" for the accumulation of sexually antagonistic variation...
  3. ncbi request reprint A worldwide polymorphism in aldehyde dehydrogenase in Drosophila melanogaster: evidence for selection mediated by dietary ethanol
    James D Fry
    Department of Biology, University of Rochester, Rochester, NY 14627, USA
    Evolution 62:66-75. 2008
    ..We present evidence that this is likely to be the result of a trade-off in catalytic activity, with the advantage of the derived allele in acetaldehyde detoxification being offset by a disadvantage in detoxification of other aldehydes...
  4. pmc On the rate and linearity of viability declines in Drosophila mutation-accumulation experiments: genomic mutation rates and synergistic epistasis revisited
    James D Fry
    Department of Biology, University of Rochester, Rochester, NY 14627, USA
    Genetics 166:797-806. 2004
    ..Because different genotypes may show very different mutational behavior, only studies using many founding genotypes can determine the average rate and distribution of effects of mutations relevant to natural populations...
  5. ncbi request reprint Genotype-environment interaction for total fitness in Drosophila
    James D Fry
    Department of Biology, University of Rochester, Rochester NY 14627 0211, USA
    J Genet 87:355-62. 2008
    ....
  6. ncbi request reprint Multilocus models of sympatric speciation: Bush versus Rice versus Felsenstein
    James D Fry
    Department of Biology, University of Rochester, Rochester, New York 14627 0211, USA
    Evolution 57:1735-46. 2003
    ..This indicates that documenting instances of sympatric species that are reproductively isolated only by host or habitat preference would provide evidence for the plausibility of sympatric speciation in nature...
  7. pmc Dominance of mutations affecting viability in Drosophila melanogaster
    James D Fry
    Department of Biology, University of Rochester, Rochester, New York 14627, USA
    Genetics 163:1357-64. 2003
    ....
  8. pmc Environment dependence of mutational parameters for viability in Drosophila melanogaster
    James D Fry
    Department of Biology, University of Rochester, Rochester, NY 14627 0211, USA
    Genetics 161:1155-67. 2002
    ..Possible reasons for this discrepancy are discussed. Regardless of the interpretation, the results show that assay conditions can have a large effect on estimates of mutational parameters for fitness traits...
  9. ncbi request reprint Rapid mutational declines of viability in Drosophila
    J D Fry
    Department of Biology, University of Rochester, Rochester, NY 14627, USA
    Genet Res 77:53-60. 2001
    ....
  10. ncbi request reprint Aldehyde dehydrogenase is essential for both adult and larval ethanol resistance in Drosophila melanogaster
    James D Fry
    Department of Biology, University of Rochester, Rochester, NY 14627, USA
    Genet Res 87:87-92. 2006
    ..The results refute the view that ALDH plays only a minor role in ethanol detoxification in larvae, and suggest that Aldh and Adh may be equally important players in the evolution of ethanol resistance in fruit-breeding Drosophila...
  11. pmc New estimates of the rates and effects of mildly deleterious mutation in Drosophila melanogaster
    J D Fry
    Department of Biology, Utah State University, Logan, UT 84322 5305, USA
    Proc Natl Acad Sci U S A 96:574-9. 1999
    ..01 in these lines), but the results also are consistent with models that include many mutations with very small effects...
  12. ncbi request reprint Environment-dependent reversal of a life history trade-off in the seed beetle Callosobruchus maculatus
    F J Messina
    Department of Biology, Utah State University, Logan, UT 84322 5305, USA
    J Evol Biol 16:501-9. 2003
    ..Despite their common dependence on resources acquired during larval stages, fecundity and lifespan in C. maculatus do not appear to be tightly coupled in a physiological or genetic sense...
  13. pmc Widespread correlations between dominance and homozygous effects of mutations: implications for theories of dominance
    Nitin Phadnis
    Department of Biology, University of Rochester, Rochester, New York 14627 0211, USA
    Genetics 171:385-92. 2005
    ..A complete explanation of dominance therefore requires either a generalization of Kacser and Burns' theory to nonenzyme genes or a new theory...
  14. pmc How common are overdominant mutations?
    James D Fry
    Genetics 167:1031-2. 2004

Research Grants4

  1. Genetic basis of clinal variation in ethanol tolerance in Drosophila melanogaster
    James Fry; Fiscal Year: 2007
    ..These insights could potentially be used to develop drug or other treatments for alcoholism. ..
  2. Genetic basis of clinal variation in ethanol tolerance in Drosophila melanogaster
    JAMES DUNCAN FRY; Fiscal Year: 2010
    ..These insights could potentially be used to develop drug or other treatments for alcoholism. ..