Research Topics
| W A FriedmanSummaryAffiliation: University of Florida Country: USA Publications
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Publications
Linear accelerator radiosurgery in the management of brain tumoursW A Friedman
Department of Neurological Surgery, University of Florida, Gainesville 32610, USA
Ann Med 32:64-80. 2000..This article presents a brief description of the linear accelerator, LINAC, radiosurgical technique, followed by a review of the more common applications of stereotactic radiosurgery in the treatment of intracranial neoplastic disease...- Linear accelerator surgery for meningiomasWilliam A Friedman
Department of Neurosurgery, University of Florida, Gainesville, Florida 32610, USA
J Neurosurg 103:206-9. 2005..In this paper the authors review the results of a single-center experience in the use of linear accelerator (LINAC) surgery for radiosurgical treatment of meningiomas... - Linear accelerator-based radiosurgery for vestibular schwannomaWilliam A Friedman
Department of Neurosurgery, UFBI, University of Florida, Gainesville 32610, USA
Neurosurg Focus 14:e2. 2003..In this report the authors specifically review the results of linear accelerator-based radiosurgery for VS and compare these outcomes with the best surgical alternatives... - Analysis of factors predictive of success or complications in arteriovenous malformation radiosurgeryWilliam A Friedman
Department of Neurosurgery, University of Florida, Gainesville, Florida 32610, USA
Neurosurgery 52:296-307; discussion 307-8. 2003..This study was undertaken to determine which factors were statistically predictive of radiological and clinical outcomes in the radiosurgical treatment of arteriovenous malformations (AVMs)... 
Linear accelerator radiosurgery for vestibular schwannomasWilliam A Friedman
Department of Neurological Surgery, University of Florida, Gainesville, FL 32610, USA
Prog Neurol Surg 21:228-37. 2008..Other institutions using modern LINAC techniques report similar excellent results. We believe that radiosurgery is the treatment of choice for smaller vestibular schwannomas...- Radiosurgery for arteriovenous malformationsWilliam A Friedman
Department of Neurological Surgery, University of Florida, Gainesville, FL 32610, USA
Neurol Res 33:803-19. 2011.... - Linear accelerator radiosurgery for vestibular schwannomasWilliam A Friedman
Department of Neurosurgery, University of Florida, Gainesville, Florida 32610, USA
J Neurosurg 105:657-61. 2006..Radiosurgery has become a popular treatment for small vestibular schwannomas (VSs). The aim of this study was to review an extensive, single-institution experience with linear accelerator (LINAC) radiosurgery for VSs... - Resident duty hours in American neurosurgeryWilliam A Friedman
Department of Neurosurgery, University of Florida, PO Box 100265, UFBI, Gainesville, FL 32610, USA
Neurosurgery 54:925-31; discussion 931-3. 2004..The new work hours have stimulated vigorous debate, both pro and con. Those arguments are reviewed... - Analytic characterization of linear accelerator radiosurgery dose distributions for fast optimizationS L Meeks
Department of Neurosurgery, University of Florida College of Medicine, Gainesville 32610 0265, USA
Phys Med Biol 44:2777-87. 1999..This provides a pseudo-inverse approach to radiosurgery optimization, based solely on geometric considerations... - Analysis of risk factors associated with radiosurgery for vestibular schwannomaK D Foote
Department of Neurosurgery, University of Florida, Gainesville, USA
J Neurosurg 95:440-9. 2001..5) A prescription dose of 12.5 Gy to the tumor margin resulted in the best combination of maximum tumor control and minimum complications in this series... - Linac scalpel radiosurgery at the University of FloridaS L Meeks
Department of Radiation Oncology, University of Florida College of Medicine, Gainesville 32610, USA
Med Dosim 23:177-85. 1998..By following practical examples of this well established system, many pitfalls in the clinical process can be avoided... - The radiobiology of radiosurgery and stereotactic radiotherapyJ M Buatti
Department of Radiation Oncology, University of Florida College of Medicine, Gainesville 32610, USA
Med Dosim 23:201-7. 1998..A discussion of these technique differences with reference to the radiobiologic implications may help elucidate the potential utility of the techniques in clinical radiotherapy... - Optic-guided stereotactic radiotherapyF J Bova
Department of Radiation Oncology, University of Florida College of Medicine, Gainesville 32610, USA
Med Dosim 23:221-8. 1998..With this system, a stereotactic radiation treatment can be delivered in the same length of time as a routine fractionated radiation treatment... - Do the morphological characteristics of arteriovenous malformations affect the results of radiosurgery?Gregory J Zipfel
Department of Neurosurgery, University of Miami, Miami, Florida, USA
J Neurosurg 101:393-401. 2004..In addition, correlation between computerized tomography (CT) scanning and angiography for the identification of AVM structures was investigated... - Initial clinical experience with frameless stereotactic radiosurgery: analysis of accuracy and feasibilityT C Ryken
Department of Neurosurgery, University of Iowa College of Medicine, Iowa City, IA, USA
Int J Radiat Oncol Biol Phys 51:1152-8. 2001..CONCLUSION: Our initial clinical experience with stereotactic radiotherapy using the infrared camera guidance system was promising, demonstrating clinical feasibility and accuracy comparable to many frame-based systems... - Calibration of three-dimensional ultrasound images for image-guided radiation therapyL G Bouchet
Department of Neurological Surgery, University of Florida, Gainesville, USA
Phys Med Biol 46:559-77. 2001..Finally, the overall tracking accuracy of our 3D ultrasound image-guided positioning system was measured to be on average 0.2 mm, 0.9 mm and 0.6 mm for the AP, lateral and axial directions respectively... - Radiosurgery using a stereotactic headframe system for irradiation of brain tumors in dogsN V Lester
Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville 32610, USA
J Am Vet Med Assoc 219:1562-7, 1550. 2001..Two dogs with meningiomas survived 227 and 56 weeks after radiosurgery. A dog with an oligodendroglioma survived 66 weeks. No complications were observed following the use of this technique... - Potential clinical efficacy of intensity-modulated conformal therapyS L Meeks
Department of Radiation Oncology, University of Florida College of Medicine, Gainesville 32610 0385, USA
Int J Radiat Oncol Biol Phys 40:483-95. 1998..The purpose of this study was to examine the potential benefit of using intensity-modulated conformal therapy for a variety of lesions currently treated with stereotactic radiosurgery or conventional radiotherapy... - Emotional conversations in Parkinson's diseaseG P Crucian
Department of Neurology, University of Florida, Gainesville 32610, USA
Neurology 56:159-65. 2001..To learn how PD influences verbal description of emotional events... - Image registration of BANG gel dose maps for quantitative dosimetry verificationS L Meeks
Department of Radiation Oncology, University of Florida College of Medicine, Gainesville 32610 0385, USA
Int J Radiat Oncol Biol Phys 43:1135-41. 1999..This paper reports on a technique for providing this correlation, thus providing a quality assurance tool that includes all of the steps of imaging, treatment planning, dose calculation, and treatment localization... - An investigation of the potential of rapid prototyping technology for image guided surgeryDidier A Rajon
Neurosurgery Department, University of Florida, Gainesville, Florida 32610, USA
J Appl Clin Med Phys 7:81-98. 2006..7 mm at the probe tip. These results demonstrate that the RP technology can be used for the fabrication of customized positioning frames for use in image-guided surgery... - The surgical treatment of trigeminal neuralgia: overview and experience at the University of FloridaPamela M Ritter
McKnight Brain Institute, University of Florida, Gainesville, FL, USA
J Neurosci Nurs 41:211-4 quiz 215-6. 2009..The short-term results of this experience are reviewed and discussed... - Rapid fabrication of custom patient biopsy guidesDidier A Rajon
Department of Neurosurgery, University of Florida, Gainesville, FL 32611, USA
J Appl Clin Med Phys 10:2897. 2009..Further tests will determine the accuracy of the positioning of the face mask on the patient's head under an IRB-approved trial judged against actual frame-based and frameless systems... - Stereotactic radiosurgery and the linear accelerator: accelerating electrons in neurosurgeryMaryam Rahman
Department of Neurosurgery, University of Florida, Gainesville, Florida 32610, USA
Neurosurg Focus 27:E13. 2009..The fascinating history of stereotactic neurosurgery is reviewed, and a detailed account is given of the development of linear accelerators and their subsequent modification for radiosurgery... - A geometrically based method of step and shoot stereotactic radiosurgery with a miniature multileaf collimatorTheodore J St John
Department of Neurosurgery, University of Florida, Gainesville, FL, USA
Phys Med Biol 50:3263-76. 2005.... - Hyponatremia in neurosurgical patients: clinical guidelines developmentMaryam Rahman
Department of Neurosurgery, University of Florida, Gainesville, Florida 32610 0265, USA
Neurosurgery 65:925-35; discussion 935-6. 2009..We critically evaluated the existing literature to identify the determinants for the development of hyponatremia and which management strategies provided the best outcomes... - Radiotherapy alone or after subtotal resection for benign skull base meningiomasWilliam M Mendenhall
Department of Radiation Oncology, University of Florida College of Medicine, Gainesville, Florida 32610, USA
Cancer 98:1473-82. 2003..The objective of the current study was to analyze the long-term local control and complications in a series of patients who were treated with radiotherapy for benign skull base meningiomas... - Management of acoustic schwannomaWilliam M Mendenhall
Department of Radiation Oncology, University of Florida College of Medicine, Gainesville, 32610 0385, USA
Am J Otolaryngol 25:38-47. 2004..To discuss the optimal management for patients with acoustic schwannoma... - Radiosurgery in the treatment of malignant gliomas: the University of Florida experienceArthur J Ulm
Department of Neurological Surgery, University of Florida, Gainesville, Florida 32610, USA
Neurosurgery 57:512-7; discussion 512-7. 2005..The possibility remains that radiosurgical boost is of benefit in recurrent tumors, especially those in RTOG Class V... - A neuropsychological outcome study of a child's left pericallosal arteriovenous malformation with occult fornix lesionT N Dikel
McKnight Brain Institute, University of Florida, Department of Clinical and Health Psychology, Education and Clinical Center, Gainesville, Florida 32610, USA
Neurocase 7:503-13. 2001.... - Linear accelerator radiosurgery in the treatment of brain metastasesArthur J Ulm
Department of Neurosurgery, University of Florida, Gainesville, Florida 32610, USA
Neurosurgery 55:1076-85. 2004..CONCLUSION: Radiosurgery is an effective and safe method for treating selected patients with brain metastases... - The effect of LINAC stereotactic radiosurgery on epilepsy associated with arteriovenous malformationsS Eisenschenk
Department of Neurology, University of Florida, Gainesville, Fla, USA
Stereotact Funct Neurosurg 71:51-61. 1998..Four of 5 patients without thrombosis became seizure-free, suggesting that structural or biochemical alterations of epileptogenic neurons following radiosurgery may reduce epileptogenicity... - Stereotactic biopsy aided by a computer graphics workstation: experience with 200 consecutive casesA J Ulm
Department of Neurological Surgery, University of Florida, Gainesville, Florida 32610, USA
Surg Neurol 56:366-71; discussion 371-2. 2001..5%). There was no mortality in this series. Symptomatic hemorrhages occurred in 4 cases (2%). CONCLUSIONS: Computer graphics workstations facilitate safe and effective biopsies in virtually any brain area... - Linear accelerator stereotactic radiosurgery for metastatic brain tumors: 17 years of experience at the University of FloridaBradley M Swinson
Department of Neurosurgery, University of Florida, Gainesville, Florida 32610, USA
Neurosurgery 62:1018-31; discussion 1031-2. 2008..To review one of the largest single-institution experiences treating metastatic brain disease with stereotactic radiosurgery... - Effect of treatment plan quality on outcomes after radiosurgery for vestibular schwannomaRichard D Beegle
Department of Neurosurgery, University of Florida, Gainesville, Florida 32610, USA
J Neurosurg 107:913-6. 2007..The goal in this study was to review the effects of treatment plan quality on outcomes after radiosurgery for vestibular schwannoma (VS)... - Radiosurgery in patients with bilateral vestibular schwannomasJay A Vachhani
Department of Neurosurgery, University of Florida, Gainesville, FL 32610, USA
Stereotact Funct Neurosurg 85:273-8. 2007..By using the untreated tumor as an internal control, one can determine whether radiosurgery was able to interrupt the natural history of the treated tumor... - Linear accelerator radiosurgery for cavernous sinus meningiomasMatthew M Kimball
Department of Neurosurgery, University of Florida, Gainesville, FL 32610, USA
Stereotact Funct Neurosurg 87:120-7. 2009..In this paper, the authors review the results of a single-center experience using linear accelerator (LINAC) radiosurgery for the treatment of cavernous sinus meningiomas... - Part III: Radiosurgery in the treatment of brain metastasesWilliam A Friedman
University of Florida, Gainesville, USA
Clin Neurosurg 51:264-70. 2004 - Salvage retreatment after failure of radiosurgery in patients with arteriovenous malformationsKelly D Foote
Department of Neurological Surgery, University of Florida College of Medicine, Gainesville, Florida, USA
J Neurosurg 98:337-41. 2003.... - Hyperbaric oxygen in the treatment of a radiosurgical complication: technical case reportMichael Lynn
Department of Neurosurgery, University of Florida, Gainesville, Florida 32610, USA
Neurosurgery 60:E579; discussion E579. 2007..We present its successful implementation for a radiosurgical complication after the treatment of a deep, large arteriovenous malformation. We also review the literature on hyperbaric oxygenation for radiation-induced complications... - Radiotherapy and radiosurgery for benign neurofibromasRahul Chopra
Department of Radiation Oncology, University of Florida College of Medicine, Gainesville, Florida 32610-0385, USA
Am J Clin Oncol 28:317-20. 2005..No significant complications related to treatment were observed. RT and SRS are likely to locally control neurofibromas in patients who require treatment and are not good candidates for complete resection... - Routine use of postoperative ICU care for elective craniotomy: a cost-benefit analysisCurtis L Beauregard
Department of Neurological Surgery, University of Florida, Gainesville, Florida 32610, USA
Surg Neurol 60:483-9; dicussion 489. 2003.... - Oligodendroglioma: does deferring treatment compromise outcome?Steven J Feigenberg
Department of Radiation Oncology, University of Florida College of Medicine, Gainesville, Florida, USA
Am J Clin Oncol 26:e60-6. 2003.... - Can standard magnetic resonance imaging reliably distinguish recurrent tumor from radiation necrosis after radiosurgery for brain metastases? A radiographic-pathological studyIvan M Dequesada
Department of Neurological Surgery, University of Florida, Gainesville, Florida 32610, USA
Neurosurgery 63:898-903; discussion 904. 2008..The purpose of this study was to determine whether standard magnetic resonance imaging (MRI) sequences could reliably distinguish between these pathological possibilities... - Radiosurgery for paraganglioma of the temporal boneSteven J Feigenberg
Department of Radiation Oncology, University of Florida Health Science Center, PO Box 100385, Gainesville, FL 32610-0385, USA
Head Neck 24:384-9. 2002..CONCLUSIONS: In this series, the results with stereotactic radiosurgery are discouraging compared with our results with conventional fractionated radiotherapy in patients with paraganglioma of the temporal bone... - Validation of the radiosurgery-based arteriovenous malformation score in a large linear accelerator radiosurgery experienceScott J Raffa
Department of Neurosurgery, University of Florida, Gainesville, Florida 32610, USA
J Neurosurg 111:832-9. 2009..This study seeks to validate independently the predictive nature of the RBAS, not only after single treatment but for retreatment, and to assess the overall outcome regardless of number of radiosurgeries... - Optical tracking technology in stereotactic radiation therapyThomas H Wagner
Department of Radiation Physics, M D Anderson Cancer Center Orlando, Orlando, FL 32806, USA
Med Dosim 32:111-20. 2007..Applications of radiotherapy optical tracking technology to respiratory gating and the monitoring of implanted fiducial markers are also discussed... - Ultrasound-guided extracranial radiosurgery: technique and applicationSanford L Meeks
Department of Radiation Oncology, University of Iowa, Iowa City, IA 52242, USA
Int J Radiat Oncol Biol Phys 55:1092-101. 2003..In this paper, we describe the system and its initial clinical application in the treatment of localized metastatic disease... - A simple and reliable index for scoring rival stereotactic radiosurgery plansThomas H Wagner
Department of Radiation Oncology, Mayo Clinic, Jacksonville, FL 32224, USA
Int J Radiat Oncol Biol Phys 57:1141-9. 2003..A simple and robust index for ranking rival stereotactic radiosurgery plans is presented... - Stereotactic radiosurgery--an organized neurosurgery-sanctioned definitionGene H Barnett
Taussig Cancer Center, Brain Tumor Institute, Cleveland, Ohio 44195, USA
J Neurosurg 106:1-5. 2007 - Radiosurgery and radiotherapy: observations and clarificationsDouglas Kondziolka
Departments of Neurological Surgery and Radiation Oncology, University of Pittsburgh, Pennsylvania 15213, USA
J Neurosurg 101:585-9. 2004..Radiosurgery and radiation therapy represent important but unique treatment paradigms for patients with certain neoplasms, vascular lesions, or functional disorders. The authors discuss their differences...