Edward S Friedman

Summary

Affiliation: University of Pittsburgh
Country: USA

Publications

  1. pmc Baseline depression severity as a predictor of single and combination antidepressant treatment outcome: results from the CO-MED trial
    Edward S Friedman
    Department of Psychiatry, University of Pittsburgh School of Medicine, PA, USA
    Eur Neuropsychopharmacol 22:183-99. 2012
  2. doi request reprint Sociodemographic, clinical, and treatment characteristics associated with worsened depression during treatment with citalopram: results of the NIMH STAR(*)D trial
    Edward S Friedman
    Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
    Depress Anxiety 26:612-21. 2009
  3. ncbi request reprint Seasonal changes in clinical status in bipolar disorder: a prospective study in 1000 STEP-BD patients
    E Friedman
    Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Acta Psychiatr Scand 113:510-7. 2006
  4. ncbi request reprint Acceptability of second-step treatments to depressed outpatients: a STAR*D report
    Stephen R Wisniewski
    Department of Psychiatry, Epidemiology Data Center, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, and Clinical Psychopharmacology Unit, Massachusetts General Hospital, Boston, USA
    Am J Psychiatry 164:753-60. 2007
  5. ncbi request reprint Cognitive therapy versus medication in augmentation and switch strategies as second-step treatments: a STAR*D report
    Michael E Thase
    Department of Psychiatry, University of Pittsburgh Medical Center, 3811 OHara St, Pittsburgh, PA 15213 2593, and Massachusetts General Hospital, USA
    Am J Psychiatry 164:739-52. 2007
  6. pmc Bipolar disorder center for Pennsylvanians: implementing an effectiveness trial to improve treatment for at-risk patients
    David J Kupfer
    Department of Psychiatry, University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, 3811 O Hara St, Pittsburgh, PA 15213, USA
    Psychiatr Serv 60:888-97. 2009
  7. pmc Concordance between clinician and patient ratings as predictors of response, remission, and recurrence in major depressive disorder
    Boadie W Dunlop
    Department of Psychiatry, Emory University School of Medicine, 1256 Briarcliff Road, Building A, 3rd Floor, Atlanta, GA 30306, USA
    J Psychiatr Res 45:96-103. 2011
  8. ncbi request reprint Prevention of recurrent episodes of depression with venlafaxine ER in a 1-year maintenance phase from the PREVENT Study
    James H Kocsis
    Department of Psychiatry, Weill Cornell Medical College, New York, NY 10012, USA
    J Clin Psychiatry 68:1014-23. 2007
  9. pmc Cognitive behavioral analysis system of psychotherapy and brief supportive psychotherapy for augmentation of antidepressant nonresponse in chronic depression: the REVAMP Trial
    James H Kocsis
    Department of Psychiatry, Weill Cornell Medical College, 1300 York Ave, New York, NY 10065, USA
    Arch Gen Psychiatry 66:1178-88. 2009
  10. ncbi request reprint Factors associated with concomitant psychotropic drug use in the treatment of major depression: a STAR*D Report
    Rchard C Shelton
    Department of Psychiatry, Vanderbilt University, Nashville, TN 37212, USA
    CNS Spectr 14:487-98. 2009

Collaborators

Detail Information

Publications27

  1. pmc Baseline depression severity as a predictor of single and combination antidepressant treatment outcome: results from the CO-MED trial
    Edward S Friedman
    Department of Psychiatry, University of Pittsburgh School of Medicine, PA, USA
    Eur Neuropsychopharmacol 22:183-99. 2012
    ..03). These data may help us to understand the impact of baseline features on antidepressant medication effectiveness and to inform the personalization of depression treatment across the spectrum of depressive severity...
  2. doi request reprint Sociodemographic, clinical, and treatment characteristics associated with worsened depression during treatment with citalopram: results of the NIMH STAR(*)D trial
    Edward S Friedman
    Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
    Depress Anxiety 26:612-21. 2009
    ..But nonresponse can include depression that worsened over the course of treatment, an outcome that has received scant attention...
  3. ncbi request reprint Seasonal changes in clinical status in bipolar disorder: a prospective study in 1000 STEP-BD patients
    E Friedman
    Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Acta Psychiatr Scand 113:510-7. 2006
    ..To investigate seasonal and regional effects on bipolar I and II patients...
  4. ncbi request reprint Acceptability of second-step treatments to depressed outpatients: a STAR*D report
    Stephen R Wisniewski
    Department of Psychiatry, Epidemiology Data Center, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, and Clinical Psychopharmacology Unit, Massachusetts General Hospital, Boston, USA
    Am J Psychiatry 164:753-60. 2007
    ..This study sought to identify factors that affect patients' willingness to accept different second-step treatment approaches...
  5. ncbi request reprint Cognitive therapy versus medication in augmentation and switch strategies as second-step treatments: a STAR*D report
    Michael E Thase
    Department of Psychiatry, University of Pittsburgh Medical Center, 3811 OHara St, Pittsburgh, PA 15213 2593, and Massachusetts General Hospital, USA
    Am J Psychiatry 164:739-52. 2007
    ..Cognitive therapy was compared with medication augmentation and switch strategies...
  6. pmc Bipolar disorder center for Pennsylvanians: implementing an effectiveness trial to improve treatment for at-risk patients
    David J Kupfer
    Department of Psychiatry, University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, 3811 O Hara St, Pittsburgh, PA 15213, USA
    Psychiatr Serv 60:888-97. 2009
    ..This report highlights the methods used to recruit, screen, and enroll a cohort of difficult-to-recruit individuals with bipolar disorder...
  7. pmc Concordance between clinician and patient ratings as predictors of response, remission, and recurrence in major depressive disorder
    Boadie W Dunlop
    Department of Psychiatry, Emory University School of Medicine, 1256 Briarcliff Road, Building A, 3rd Floor, Atlanta, GA 30306, USA
    J Psychiatr Res 45:96-103. 2011
    ..Poor agreement between patient- and clinician-ratings of depression severity is primarily a state phenomenon, although it is trait-like for some patients...
  8. ncbi request reprint Prevention of recurrent episodes of depression with venlafaxine ER in a 1-year maintenance phase from the PREVENT Study
    James H Kocsis
    Department of Psychiatry, Weill Cornell Medical College, New York, NY 10012, USA
    J Clin Psychiatry 68:1014-23. 2007
    ..To test the long-term efficacy and safety of venlafaxine extended-release (ER) in preventing recurrence in patients with major depression...
  9. pmc Cognitive behavioral analysis system of psychotherapy and brief supportive psychotherapy for augmentation of antidepressant nonresponse in chronic depression: the REVAMP Trial
    James H Kocsis
    Department of Psychiatry, Weill Cornell Medical College, 1300 York Ave, New York, NY 10065, USA
    Arch Gen Psychiatry 66:1178-88. 2009
    ..Previous studies have found that few chronically depressed patients remit with antidepressant medications alone...
  10. ncbi request reprint Factors associated with concomitant psychotropic drug use in the treatment of major depression: a STAR*D Report
    Rchard C Shelton
    Department of Psychiatry, Vanderbilt University, Nashville, TN 37212, USA
    CNS Spectr 14:487-98. 2009
    ..Concomitant psychotropic medication (CPM) treatment is common in persons with major depression (MDD). However, relationships with patient characteristics and response to treatment are unclear...
  11. doi request reprint Toward clinically useful neuroimaging in depression treatment: prognostic utility of subgenual cingulate activity for determining depression outcome in cognitive therapy across studies, scanners, and patient characteristics
    Greg J Siegle
    Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, 3811 O Hara St, Pittsburgh, PA 15213, USA
    Arch Gen Psychiatry 69:913-24. 2012
    ..Subgenual anterior cingulate activity, in particular, may reflect processes that interfere with treatment (eg, emotion generation) in addition to its putative regulatory role; alternately, its absence may facilitate treatment response...
  12. pmc Early adverse events and attrition in selective serotonin reuptake inhibitor treatment: a suicide assessment methodology study report
    Diane Warden
    Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX 75390 9119, USA
    J Clin Psychopharmacol 30:259-66. 2010
    ..Neither global ratings nor specific adverse effects at week 2 were related to patient attrition during SSRI treatment. Other factors seem to contribute to patient decisions about continuing with treatment...
  13. ncbi request reprint Effects of sertraline on sleep architecture in patients with depression
    Ripu D Jindal
    Department of Psychiatry, University of Pittsburgh School of Medicine WPIC, 3811 O Hara Street, Pittsburgh, PA 15213, USA
    J Clin Psychopharmacol 23:540-8. 2003
    ..Further studies are needed to examine the effects of SSRIs in acute treatment of depressed patients with severe insomnia, and the relationship of acute changes and relapse prevention of recurrent depression...
  14. pmc Correlation between patient and clinician assessments of depression severity in the PREVENT study
    Boadie W Dunlop
    Department of Psychiatry, Emory University School of Medicine, Atlanta, GA, USA
    Psychiatry Res 177:177-83. 2010
    ..This study analyzed agreement between commonly used depression rating scales in the Prevention of Recurrent Episodes of Depression with Venlafaxine Extended Release (ER) for Two Years (PREVENT) trial...
  15. doi request reprint Lithium treatment -- moderate dose use study (LiTMUS) for bipolar disorder: rationale and design
    Andrew A Nierenberg
    Department of Psychiatry, Massachusetts General Hospital, Boston, MA 02114, USA
    Clin Trials 6:637-48. 2009
    ..Recent data indicate that lithium use for bipolar disorder has declined over the last decade and that lithium largely has been replaced with alternate, commercially promoted medications that may or may not result in better outcomes...
  16. pmc Cognitive reactivity, dysfunctional attitudes, and depressive relapse and recurrence in cognitive therapy responders
    Robin B Jarrett
    Department of Psychiatry, The University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390 9149, USA
    Behav Res Ther 50:280-6. 2012
    ..While findings cannot be generalized beyond CT responders, they emphasize the clinical importance of reducing dysfunctional attitudes in preventing depression...
  17. doi request reprint Remission prognosis for cognitive therapy for recurrent depression using the pupil: utility and neural correlates
    Greg J Siegle
    Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    Biol Psychiatry 69:726-33. 2011
    ..This study examined 1) whether pretreatment assessment of pupillary responses to negative information were associated with remission in CT and 2) their associated brain mechanisms...
  18. ncbi request reprint Differential effects of nefazodone and cognitive behavioral analysis system of psychotherapy on insomnia associated with chronic forms of major depression
    Michael E Thase
    Department of Psychiatry, University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, PA 15213 2593, USA
    J Clin Psychiatry 63:493-500. 2002
    ..As nefazodone-mediated blockade of serotonin-2 receptors may directly relieve insomnia associated with depression, we examined the more specific effects of CBASP and nefazodone, singly and in combination, on sleep disturbances...
  19. pmc Association study of 21 circadian genes with bipolar I disorder, schizoaffective disorder, and schizophrenia
    Hader A Mansour
    Department of Psychiatry, University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, PA 15213, USA
    Bipolar Disord 11:701-10. 2009
    ..The results are plausible, based on prior studies of circadian abnormalities. As replications have not been attempted uniformly, we evaluated representative, common polymorphisms in all three disorders...
  20. pmc Enhancing outcomes in patients with bipolar disorder: results from the Bipolar Disorder Center for Pennsylvanians Study
    Andrea Fagiolini
    Department of Psychiatry, University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, PA 15213, USA
    Bipolar Disord 11:382-90. 2009
    ..We investigated whether SCBD and ECI + SCBD are able to improve outcomes and reduce health disparities for young and elderly individuals, African Americans, and rural residents with bipolar disorder...
  21. doi request reprint Medical monitoring in patients with bipolar disorder: clinical recommendations
    Edward S Friedman
    Department of Psychiatry, University of Pittsburgh Medical Center and Western Psychiatric Institute and Clinic, Pittsburgh, Pennsylvania, USA
    J Clin Psychiatry 70:e27. 2009
    ..Different health tests are needed depending on the type of medication the patient is prescribed...
  22. ncbi request reprint Electroencephalographic sleep profiles in single-episode and recurrent unipolar forms of major depression: II. Comparison during remission
    Ripu D Jindal
    Department of Psychiatry, University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, Pennsylvania 15213, USA
    Biol Psychiatry 51:230-6. 2002
    ..This study examines whether the observed differences in the sleep patterns during recurrent and single-episode depression persist into remission following nonpharmacologic treatment...
  23. ncbi request reprint Serotonin gene polymorphisms and bipolar I disorder: focus on the serotonin transporter
    Hader A Mansour
    Department of Psychiatry, University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, 3811 O Hara Street, Pittsburgh, PA 15213, U S A
    Ann Med 37:590-602. 2005
    ..Our analyses do not support association between SLC6A4 and BDI families. Further studies using sub-groups of BDI are worthwhile...
  24. ncbi request reprint Coinheritance of BRCA1 and BRCA2 mutations with Fanconi anemia and Bloom syndrome mutations in Ashkenazi Jewish population: possible role in risk modification for cancer development
    M Koren-Michowitz
    Department of Pediatric Hematology Oncology, Sheba Medical Center, Tel Hashomer, Israel
    Am J Hematol 78:203-6. 2005
    ..Coinheritance of FA and/or BS mutations seems to be more prevalent among BRCA mutation carriers, but a larger study encompassing more women may help in clarifying this issue...
  25. ncbi request reprint Population attributes affecting the prevalence of BRCA mutation carriers in epithelial ovarian cancer cases in israel
    G Hirsh-Yechezkel
    Cancer Epidemiology Unit, Gertner Institute for Epidemiology and Health Policy Research, Tel Hashomer, Israel
    Gynecol Oncol 89:494-8. 2003
    ..The objective was to evaluate the prevalence of BRCA1/2 mutations in selected categories of ovarian cancer patients in Israel...
  26. ncbi request reprint Codon 72 polymorphism of p53 in Israeli Jewish cervical cancer patients and healthy women
    S Arbel-Alon
    Gynecologic Oncology Unit, Department of Obstetrics and Gynecology, Edith Wolfson Medical Center, Holon, Israel
    Int J Gynecol Cancer 12:741-4. 2002
    ..10.8%; P < 0.01). It may be assumed that the low incidence of cervical cancer in Israeli Jewish women and the differences between the ethnic groups may be related to the frequency pattern of the homozygous arginine p53 polymorphism..
  27. ncbi request reprint Increased association of brain protein kinase C with the receptor for activated C kinase-1 (RACK1) in bipolar affective disorder
    H Wang
    Laboratory of Molecular Pharmacology, MCP Hahnemann School of Medicine, 245 N. 15th Street, Philadelphia, PA 19102, USA
    Biol Psychiatry 50:364-70. 2001
    ....