Research Topics
Genomes and Genes | Errol FriedbergSummaryAffiliation: University of Texas Southwestern Medical Center Country: USA Publications
Research Grants
| Collaborators
|
Detail Information
Publications
Suffering in silence: the tolerance of DNA damageErrol C Friedberg
Laboratory of Molecular Pathology, Department of Pathology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9072, USA
Nat Rev Mol Cell Biol 6:943-53. 2005..A second category of tolerance mechanism involves alternative replication strategies that obviate the need to replicate directly across sites of template-strand damage...- The eureka enzyme: the discovery of DNA polymeraseErrol C Friedberg
Laboratory of Molecular Pathology, Department of Pathology, University of Texas Southwestern Medical Center, Dallas, Texas 79503 9072, USA
Nat Rev Mol Cell Biol 7:143-7. 2006..At the time, most scientists in the field believed that DNA synthesis was too complicated to be accurately reflected outside the living cell... - Hot news: temperature-sensitive humans explain hereditary diseaseE C Friedberg
Laboratory of Molecular Pathology, Department of Pathology, University of Texas Southwestern Medical Center, Dallas, TX 75390 9072, USA
Bioessays 23:671-3. 2001..1) Specifically, several patients have been shown to carry a mutation in the XPD gene, which encodes a thermolabile form of XPD protein, resulting in loss of hair during febrile episodes... - A brief history of the DNA repair fieldErrol C Friedberg
Laboratory of Molecular Pathology, Department of Pathology, University of Texas Southwestern Medical Center at Dallas, Dallas, TX, USA
Cell Res 18:3-7. 2008..Since then multiple DNA repair mechanisms, as well as other biological responses to DNA damage, have been discovered and their regulation has been studied. This article briefly recounts the early history of this field... - Database of mouse strains carrying targeted mutations in genes affecting biological responses to DNA damage (Version 6)Errol C Friedberg
Laboratory of Molecular Pathology, Department of Pathology, University of Texas Southwestern Medical Center, Dallas, TX 75390 9072, USA
DNA Repair (Amst) 3:1617-38. 2004..We present Version 6 of a database of mouse mutant strains that affect biological responses to DNA damage. This database is also electronically available at http://pathcuric1.swmed.edu/research/research.htm... - Database of mouse strains carrying targeted mutations in genes affecting biological responses to DNA damage. Version 5Errol C Friedberg
Laboratory of Molecular Pathology, Department of Pathology, University of Texas Southwestern Medical Center, Dallas, TX 75390 9072, USA
DNA Repair (Amst) 2:501-30. 2003..Most of the mice listed in the database were generated by conventional targeted gene replacement technologies... - New insights into the combined Cockayne/xeroderma pigmentosum complex: human XPG protein can function in transcription factor stabilityErrol C Friedberg
Laboratory of Molecular Pathology, Department of Pathology, University of Texas Southwestern Medical Center, Dallas, TX 75390 9072, USA
Mol Cell 26:162-4. 2007..2007], this issue of Molecular Cell). This observation likely explains some of the clinical features of individuals with both defective DNA repair and development... 
Nucleotide excision repair of DNA: The very early historyErrol C Friedberg
Laboratory of Molecular Pathology, Department of Pathology, University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390 9072, USA
DNA Repair (Amst) 10:668-72. 2011..This article, taken largely from the book Correcting the Blueprint of Life: An Historical Account of the Discovery of DNA Repair Mechanisms, summarizes the very early history of the discovery of nucleotide excision repair...- Database of mouse strains carrying targeted mutations in genes affecting biological responses to DNA damage Version 7Errol C Friedberg
Laboratory of Molecular Pathology, Department of Pathology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390 9072, USA
DNA Repair (Amst) 5:189-209. 2006..We present Version 7 of a database of mouse mutant strains that affect biological responses to DNA damage. This database is also electronically available at http://pathcuricl.swmed.edu/research/research.htm... - The role of endogenous and exogenous DNA damage and mutagenesisErrol C Friedberg
Laboratory of Molecular Pathology, Department of Pathology, University of Texas Southwestern Medical Center, Dallas, TX 75390 9072, USA
Curr Opin Genet Dev 14:5-10. 2004..This article presents some of the highlights in this area of investigation, with a particular emphasis on DNA repair, the tolerance of DNA damage and its contribution to mutagenesis, and DNA damage checkpoint regulation... - Error-prone DNA polymerases: novel structures and the benefits of infidelityE C Friedberg
Laboratory of Molecular Pathology, Department of Pathology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
Cell 107:9-12. 2001.... - A comprehensive catalogue of somatic mutations in cancer genomesErrol C Friedberg
Department of Pathology, The University of Texas Southwestern Medical Center at Dallas, 75390, USA
DNA Repair (Amst) 9:468-9. 2010..Among other observations the studies suggest the operation of novel DNA repair mechanisms or modes... - How nucleotide excision repair protects against cancerE C Friedberg
Department of Pathology, University of Texas Southwestern Medical Center, Dallas 75390 9072, USA
Nat Rev Cancer 1:22-33. 2001..How does NER protect against skin cancer and possibly other types of environmentally induced cancer in humans?.. - Specialized DNA polymerases, cellular survival, and the genesis of mutationsErrol C Friedberg
Laboratory of Molecular Pathology, Department of Pathology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
Science 296:1627-30. 2002..The low fidelity of some of these specialized polymerases when copying undamaged DNA may be physiologically functional, including generating immunoglobulin diversity... - REV1 protein interacts with PCNA: significance of the REV1 BRCT domain in vitro and in vivoCaixia Guo
Laboratory of Molecular Pathology, Department of Pathology, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA
Mol Cell 23:265-71. 2006..In vivo studies in both chicken DT40 cells and yeast directly support the requirement of the BRCT domain of REV1 for cell survival and DNA damage-induced mutagenesis... 
Celebrating 40 years of biochemistry in EuropeErrol C Friedberg
Laboratory of Molecular Pathology, Department of Pathology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
Genome Biol 5:344. 2004- Human DNA polymerase kappa bypasses and extends beyond thymine glycols during translesion synthesis in vitro, preferentially incorporating correct nucleotidesPaula L Fischhaber
Laboratory of Molecular Pathology, Department of Pathology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9072, USA
J Biol Chem 277:37604-11. 2002..Our findings suggest a role for polkappa in both nonmutagenic and mutagenic bypass of oxidative damage... - Requirements for the interaction of mouse Polkappa with ubiquitin and its biological significanceCaixia Guo
Laboratory of Molecular Pathology, Department of Pathology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9072, USA
J Biol Chem 283:4658-64. 2008..However, the ubiquitin-binding motifs do not affect Polkappa half-life. Finally, we have examined levels of Polkappa expression following the exposure of mouse cells to benzo[a]pyrene-dihydrodiol epoxide or UVB radiation... - Mice defective in the mismatch repair gene Msh2 show increased predisposition to UVB radiation-induced skin cancerLisiane B Meira
Laboratory of Molecular Pathology, Department of Pathology, Southwestern Medical Center, University of Texas, Dallas, TX 75235, USA
DNA Repair (Amst) 1:929-34. 2002.... - Trading places: how do DNA polymerases switch during translesion DNA synthesis?Errol C Friedberg
Laboratory of Molecular Pathology, Department of Pathology, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA
Mol Cell 18:499-505. 2005..This review addresses recent advances in our understanding of DNA polymerase switching during TLS in bacteria such as E. coli and in lower and higher eukaryotes... - TERF2-XPF: caught in the middle; beginnings from the endLisa D McDaniel
Laboratory of Molecular Pathology, Department of Pathology, University of Texas Southwestern Medical Center, Dallas, 75390, USA
DNA Repair (Amst) 5:868-72. 2006..Here, we review these exciting findings that suggest new roles for the TERF2-XPF complex and point out several questions that remain to be addressed... - Maurice Wilkins (1916-2004)Errol C Friedberg
Department of Pathology, University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390, USA
Mol Cell 16:671-2. 2004 - How are specialized (low-fidelity) eukaryotic polymerases selected and switched with high-fidelity polymerases during translesion DNA synthesis?Paula L Fischhaber
Laboratory of Molecular Pathology, Department of Pathology, University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390 9072, USA
DNA Repair (Amst) 4:279-83. 2005..Recent studies in the literature provide hints of the complexity of DNA switching between polymerases for translesion DNA synthesis (TLS) and those for normal DNA replication... - Reversible monoubiquitination of PCNA: A novel slant on regulating translesion DNA synthesisErrol C Friedberg
Laboratory of Molecular Pathology, Department of Pathology, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA
Mol Cell 22:150-2. 2006..Huang et al. (2006) report the regulation of monoubiquitination of PCNA by autocleavage of a DUB called USP1 in cells exposed to UV radiation... 
Mapping of a single locus capable of complementing the defective heterochromatin phenotype of Roberts syndrome cellsLisa D McDaniel
Department of Pathology, University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390 9072, USA
Am J Hum Genet 77:132-9. 2005..The results are consistent with the notion that the single gene defect responsible for heterochromatic splaying and developmental abnormalities maps to chromosome 8p21...- The discovery that xeroderma pigmentosum (XP) results from defective nucleotide excision repairErrol C Friedberg
Laboratory of Molecular Pathology, Department of Pathology, University of Texas Southwestern Medical Center, Dallas, 75390 9072, USA
DNA Repair (Amst) 3:183, 195. 2004..This discovery by James Cleaver had an important impact on our understanding of nucleotide excision repair in mammals... - Y-family DNA polymerases in mammalian cellsCaixia Guo
Laboratory of Molecular Pathology, Department of Pathology, University of Texas Southwestern Medical Center, Dallas, TX 75390 9072, USA
Cell Mol Life Sci 66:2363-81. 2009.... - Report on the First US-Japan DNA Repair Meeting. Sendai, Japan, October 27-31, 2002Errol C Friedberg
Laboratory of Molecular Pathology, Department of Pathology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390-9072, USA
DNA Repair (Amst) 2:639-52. 2003 - DNA damage and repairErrol C Friedberg
Laboratory of Molecular Pathology, Department of Pathology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9072
Nature 421:436-40. 2003..Although mutations or deficiencies in repair can have catastrophic consequences, causing a range of human diseases, mutations are nonetheless fundamental to life and evolution... - DNA polymerases for translesion DNA synthesis: enzyme purification and mouse models for studying their functionPaula L Fischhaber
Department of Pathology, University of Texas Southwestern Medical Center, Dallas, USA
Methods Enzymol 408:355-78. 2006..It also describes some of the methods employed in the evaluation of mouse strains defective in genes that encode these enzymes... - Validation of XP-C pathogenic variations in archival material from a live XP patientLisa D McDaniel
Laboratory of Molecular Pathology, Department of Pathology, University of Texas Southwestern Medical Center, Dallas, TX 75390 9072, USA
DNA Repair (Amst) 6:115-20. 2007.... - The intersection between the birth of molecular biology and the discovery of DNA repairErrol C Friedberg
Department of Pathology, Laboratory of Molecular Pathology, University of Texas Southwestern Medical Center, Dallas, TX 75390 9072, USA
DNA Repair (Amst) 1:855-67. 2002.... - Polk mutant mice have a spontaneous mutator phenotypeJ Nicole Kosarek Stancel
Laboratory of Molecular Pathology, Department of Pathology, University of Texas Southwestern Medical Center, Dallas, TX 75390 9072, USA
DNA Repair (Amst) 8:1355-62. 2009..These results are consistent with the notion that Pol kappa is required for accurate translesion DNA synthesis past naturally occurring polycyclic guanine adducts, possibly generated by cholesterol and/or its metabolites... - Obituary: Arthur Kornberg (1918-2007)Errol C Friedberg
University of Texas Southwestern Medical Center, Laboratory of Molecular Pathology, Department of Pathology, Dallas, TX 75390-9072, USA
DNA Repair (Amst) 7:135. 2008 - Ubiquitin-binding motifs in REV1 protein are required for its role in the tolerance of DNA damageCaixia Guo
Laboratory of Molecular Pathology, Department of Pathology, University of Texas Southwestern Medical Center, Dallas, TX 75390 9072, USA
Mol Cell Biol 26:8892-900. 2006..In cells exposed to UV radiation, the association of REV1 with replication foci is dependent on functional UBMs. The UBMs of REV1 are shown to contribute to DNA damage tolerance and damage-induced mutagenesis in vivo... - Inroads into base excision repair II. The discovery of DNA glycosylases. "An N-glycosidase from Escherichia coli that releases free uracil from DNA containing deaminated cytosine residues," Proc. Nat. Acad. Sci. USA, 1974Errol C Friedberg
Laboratory of Molecular Pathology, Department of Pathology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
DNA Repair (Amst) 3:1532-6; discussion 1531-2. 2004..The discovery of a DNA glycosylase that specifically removes uracil from DNA, opened the door for uncovering a large class of such enzymes that are fundamental to the process of base excision repair of DNA... - Mutations in the Trp53 gene of UV-irradiated Xpc mutant mice suggest a novel Xpc-dependent DNA repair processDorit Nahari
Laboratory of Molecular Pathology, Department of Pathology, University of Texas, Southwestern Medical Center, Dallas, TX 75390 9072, USA
DNA Repair (Amst) 3:379-86. 2004.... - A novel XPC pathogenic variant detected in archival material from a patient diagnosed with Xeroderma Pigmentosum: a case report and review of the genetic variants reported in XPCAmanda Rivera Begeman
Laboratory of Molecular Pathology, Department of Pathology, University of Texas Southwestern Medical Center, Dallas, TX 75390 9072, USA
DNA Repair (Amst) 6:100-14. 2007.... - Mouse Rev1 protein interacts with multiple DNA polymerases involved in translesion DNA synthesisCaixia Guo
Laboratory of Molecular Pathology, Department of Pathology, University of Texas Southwestern Medical Center, Dallas, TX 75390 9072, USA
EMBO J 22:6621-30. 2003..Our observations suggest that Rev1 plays a role(s) in mediating protein-protein interactions among DNA polymerases required for TLS. The precise function(s) of these interactions during TLS remains to be determined... - The 3rd Japan-US DNA Repair Meeting, Sendai, Japan, May 7-11, 2007Errol C Friedberg
Laboratory of Molecular Pathology, Department of Pathology, University of Texas Southwestern Medical Center, Dallas, TX 75390-9072, USA
DNA Repair (Amst) 6:1545-55. 2007 - DNA repair: from molecular mechanism to human diseaseErrol C Friedberg
Department of Pathology, University of Texas Southwestern, Medical Center at Dallas, 75390, USA
DNA Repair (Amst) 5:986-96. 2006 - Constitutive and regulated expression of the mouse Dinb (Polkappa) gene encoding DNA polymerase kappaSusana Velasco-Miguel
Department of Pathology, University of Texas Southwestern Medical Center, Dallas, TX 73590 9013, USA
DNA Repair (Amst) 2:91-106. 2003..The mouse (but not the human) Polkappa gene is primarily regulated by the p53 gene and is upregulated in response to exposure to various DNA-damaging agents in a p53-dependent manner... - TB or Not TB: how Mycobacterium tuberculosis may evade drug treatmentErrol C Friedberg
Department of Pathology, University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390, USA
Cell 113:139-40. 2003..This may be an important mechanism for generating drug-resistant strains of M. tuberculosis... - Reminiscences of a long-time colleague and friend, Philip C. HanawaltErrol C Friedberg
Laboratory of Molecular Pathology, Department of Pathology, University of Texas Southwestern Medical Center, Dallas, TX 75390 9072, USA
Mutat Res 577:9-13. 2005..Philip Hanawalt is a long time contributor to many areas of the DNA repair field. This article summarizes aspect of his relationship with the author over the past 36 years... - Comparative analysis of in vivo interactions between Rev1 protein and other Y-family DNA polymerases in animals and yeastsJ Nicole Kosarek
Department of Pathology, University of Texas Southwestern Medical Center, Dallas, TX 75390 9072, USA
DNA Repair (Amst) 7:439-51. 2008..The results of this study suggest that special consideration should be exercised when making mechanistic extrapolations regarding translesion DNA synthesis from one eukaryotic system to another... - Multiple PolK (POLK) transcripts in mammalian testisCaixia Guo
Laboratory of Molecular Pathology, Department of Pathology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390 9072, USA
DNA Repair (Amst) 4:397-402. 2005..The multiple mouse/human (PolK/POLK) transcripts may encode multiple Polkappa isoforms in testis... - Impaired genome maintenance suppresses the growth hormone--insulin-like growth factor 1 axis in mice with Cockayne syndromeIngrid van der Pluijm
Department of Genetics, Center for Biomedical Genetics, Erasmus University Medical Center, Rotterdam, The Netherlands
PLoS Biol 5:e2. 2007..Importantly, wild-type mice exposed to a low dose of chronic genotoxic stress recapitulated this response, thereby pointing to a novel link between genome instability and the age-related decline of the somatotroph axis... - The combined effects of xeroderma pigmentosum C deficiency and mutagens on mutation rates in the mouse germ lineLaurent Miccoli
Commissariat a l Energie Atomique, Laboratoire de Génétique de la Radiosensibilité, Institut de Radiobiologie Cellulaire et Moleculaire, Direction des Sciences du Vivant, Fontenay aux Roses, France
Cancer Res 67:4695-9. 2007.... - Mutagenesis in the spotlightErrol C Friedberg
DNA Repair (Amst) 1:109. 2002 - Identification of MMS19 domains with distinct functions in NER and transcriptionMelissa D Hatfield
Department of Otorhinolaryngology, University of Oklahoma Health Sciences Center, Oklahoma City, 73104, USA
DNA Repair (Amst) 5:914-24. 2006..Furthermore, our work associates for the first time specific protein domains with MMS19's role in NER and transcription... - Elevated mutation rates in the germline of Polkappa mutant male miceKaren L A Burr
Department of Genetics, University of Leicester, University Road, Leicester LE1 7RH, UK
DNA Repair (Amst) 5:860-2. 2006..We suggest that compromised translesion synthesis in Polkappa(-/-) mice may result in replication fork pausing which, in turn, may affect ESTR mutation rate... - Use of nucleotide excision repair-deficient mice as a model for chemically induced lung cancerDavid L Cheo
Life Technologies Division, Invitrogen Corporation, Rockville, MD, USA
Methods Mol Med 74:481-91. 2003 - Mouse mutant database relevant to cellular responses to DNA damageErrol C Friedberg
DNA Repair (Amst) 1:341. 2002 - UVB radiation-induced cancer predisposition in Cockayne syndrome group A (Csa) mutant miceGijsbertus T J van der Horst
Department of Cell Biology and Genetics, Medical Genetics Centre, Erasmus University Rotterdam, The Netherlands
DNA Repair (Amst) 1:143-57. 2002.... - Reflections on the 8th international conference on environmental mutagensBryn A Bridges
Centre for Genome Damage and Stability, University of Sussex, Falmer, Brighton, BN1 9RR, UK
DNA Repair (Amst) 1:169-74. 2002 - Apurinic/apyrimidinic endonuclease (APE/REF-1) haploinsufficient mice display tissue-specific differences in DNA polymerase beta-dependent base excision repairJulian J Raffoul
Department of Nutrition and Food Science, Wayne State University, Detroit, Michigan 48202, USA
J Biol Chem 279:18425-33. 2004.... - Quantitative analysis of translesion DNA synthesis across a benzo[a]pyrene-guanine adduct in mammalian cells: the role of DNA polymerase kappaSharon Avkin
Department of Biological Chemistry, Weizmann Institute of Science, Rehovot 76100, Israel
J Biol Chem 279:53298-305. 2004..These results indicate that BP-G is bypassed in mammalian cells with relatively high efficiency and that polkappa bypasses BP-G in vivo with higher efficiency and higher accuracy than other DNA polymerases... - Gene transduction in skin cells: preventing cancer in xeroderma pigmentosum miceMaria Carolina N Marchetto
Department of Microbiology, Institute of Biomedical Sciences, , , SP, Brazil
Proc Natl Acad Sci U S A 101:17759-64. 2004..Thus, efficient adenovirus gene delivery to the skin is a promising tool for reconstitution of specific DNA repair defects in XP patients... - The yeast Rad7/Rad16/Abf1 complex generates superhelical torsion in DNA that is required for nucleotide excision repairShirong Yu
Department of Pathology, University of Wales College of Medicine, Cardiff CF14 4XN, Wales, UK
DNA Repair (Amst) 3:277-87. 2004..We conclude that in yeast the molecular mechanism of NER includes the generation of superhelical torsion in DNA... - Involvement of vertebrate Polkappa in translesion DNA synthesis across DNA monoalkylation damageKatsuya Takenaka
Department of Radiation Genetics, Graduate School of Medicine, Kyoto University, Kyoto 606 8501, Japan
J Biol Chem 281:2000-4. 2006..These data imply that Polkappa has a function in TLS past alkylated base adducts as well as UV radiation DNA damage in vertebrates... - Deletion of XPC leads to lung tumors in mice and is associated with early events in human lung carcinogenesisM Christine Hollander
National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
Proc Natl Acad Sci U S A 102:13200-5. 2005..Coupled with cigarette carcinogens, decreased DNA repair would lead to additional mutations in genes such as p53 that are frequent targets in lung cancer... - Growth of a journalErrol C Friedberg
DNA Repair (Amst) 4:1. 2005 - Detoxification of olefinic epoxides and nucleotide excision repair of epoxide-mediated DNA damage: Insights from animal models examining human sensitivity to 1,3-butadieneJeffrey K Wickliffe
Department of Preventive Medicine and Community Health, University of Texas Medical Branch, Galveston, TX 77555, USA
Chem Biol Interact 166:226-31. 2007.... - DNA Repair-responses to DNA damage and other aspects of genomic stability. A new journal formatErrol C Friedberg
DNA Repair (Amst) 1:1-2. 2002 - DNA polymerase kappa deficiency does not affect somatic hypermutation in miceDominik Schenten
Institute for Genetics, University of Cologne, Cologne, Germany
Eur J Immunol 32:3152-60. 2002..However, pol kappa-deficient embryonic fibroblasts are abnormally sensitive to killing following exposure to ultraviolet (UV) radiation, suggesting a role of pol kappa in translesion DNA synthesis... - How e-mail raises the spectre of a digital Dark AgeErrol C Friedberg
Nature 423:801. 2003 - Happy 5th birthday, DNA RepairErrol C Friedberg
DNA Repair (Amst) 6:271-3. 2007 - Report of the Working Group on Integrated Translational Research in DNA RepairLeslie Reinlib
Division of Extramural Research and Training, National Institute of Environmental Health Sciences, National Institutes of Health, U S Department of Health and Human Services, Research Triangle Park, NC 27709, USA
DNA Repair (Amst) 6:145-7. 2007..This report summarizes the rationale for this initiative and the recommendations that emerged... - A novel p53 mutational hotspot in skin tumors from UV-irradiated Xpc mutant mice alters transactivation functionsAlberto Inga
Laboratory of Molecular Genetics, National Institute of Environmental Health Sciences, NIH, PO Box 12233, Research Triangle Park, North Carolina, NC 27709, USA
Oncogene 21:5704-15. 2002..Furthermore, the approach that we have taken also provides for the dissection of functions that may be retained in many p53 tumor alleles...
Research Grants
- DNA REPAIR AND ITS RELATIONSHIP TO CARCINOGENESISErrol Friedberg; Fiscal Year: 2001..There is reason to believe that the proteins encoded by these genes operate in a different chromatin-modulating complex, and it is proposed to isolate and characterize this putative complex as well. ..
- DNA REPAIR AND CANCER PRONE HEREDITARY HUMAN DISEASEErrol Friedberg; Fiscal Year: 2002....
- MOUSE MODELS OF DNA REPAIR - DEFECTIVE HUMAN DISEASESErrol Friedberg; Fiscal Year: 2007....
- DNA REPAIR AND CANCER-PRONE HEREDITARY HUMAN DISEASEErrol Friedberg; Fiscal Year: 1993....
- DNA REPAIR AND CANCER-PRONE HEREDITARY HUMAN DISEASEErrol Friedberg; Fiscal Year: 1992....
- MOUSE MODELS OF DNA REPAIR - DEFECTIVE HUMAN DISEASESErrol Friedberg; Fiscal Year: 2011..abstract_text> ..