Nathaniel M Fried

Summary

Affiliation: University of North Carolina at Charlotte
Country: USA

Publications

  1. ncbi request reprint New laser treatment approaches for benign prostatic hyperplasia
    Nathaniel M Fried
    Department of Physics and Optical Science, University of North Carolina at Charlotte, 9201 University City Boulevard, Charlotte, NC 28223 0001, USA
    Curr Urol Rep 8:47-52. 2007
  2. doi request reprint Noncontact stimulation of the cavernous nerves in the rat prostate using a tunable-wavelength thulium fiber laser
    Nathaniel M Fried
    Department of Physics and Optical Science, University of North Carolina at Charlotte, North Carolina 28223 0001, USA
    J Endourol 22:409-13. 2008
  3. doi request reprint Laser stimulation of the cavernous nerves in the rat prostate, in vivo: optimization of wavelength, pulse energy, and pulse repetition rate
    Nathaniel M Fried
    Department of Physics and Optical Science at the University of North Carolina at Charlotte, NC 28223, USA
    Conf Proc IEEE Eng Med Biol Soc 2008:2777-80. 2008
  4. ncbi request reprint Imaging the cavernous nerves in the rat prostate using optical coherence tomography
    Nathaniel M Fried
    Department of Urology, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    Lasers Surg Med 39:36-41. 2007
  5. doi request reprint Temperature-controlled optical stimulation of the rat prostate cavernous nerves
    Serhat Tozburun
    University of North Carolina at Charlotte, Department of Physics and Optical Science, Charlotte, North Carolina 28223 0001, USA
    J Biomed Opt 18:067001. 2013
  6. doi request reprint Optical coherence tomography of cavernous nerves: a step toward real-time intraoperative imaging during nerve-sparing radical prostatectomy
    Soroush Rais-Bahrami
    James Buchanan Brady Urological Institute, Johns Hopkins Medical Institutions, Bethesda, Maryland 21287, USA
    Urology 72:198-204. 2008
  7. doi request reprint Noninvasive thermal coagulation of deep subsurface tissue structures using a laser probe with integrated contact cooling
    Christopher M Cilip
    Department of Physics and Optical Science, University of North Carolina at Charlotte, NC 28223, USA
    Conf Proc IEEE Eng Med Biol Soc 2008:3657-60. 2008
  8. ncbi request reprint Side-firing germanium oxide optical fibers for use with erbium:YAG laser
    Anthony K Ngo
    Department of Electrical and Computer Engineering, Johns Hopkins University, Baltimore, Maryland, USA
    J Endourol 20:475-8. 2006
  9. ncbi request reprint Comparison of germanium oxide fibers with silica and sapphire fiber tips for transmission of erbium: YAG laser radiation
    Travis J Polletto
    Department of Urology, Johns Hopkins University, Baltimore, Maryland 21224, USA
    Lasers Surg Med 38:787-91. 2006
  10. ncbi request reprint High-power thulium fiber laser ablation of urinary tissues at 1.94 microm
    Nathaniel M Fried
    Department of Urology, Johns Hopkins School of Medicine, Baltimore, Maryland 21224, USA
    J Endourol 19:25-31. 2005

Collaborators

Detail Information

Publications48

  1. ncbi request reprint New laser treatment approaches for benign prostatic hyperplasia
    Nathaniel M Fried
    Department of Physics and Optical Science, University of North Carolina at Charlotte, 9201 University City Boulevard, Charlotte, NC 28223 0001, USA
    Curr Urol Rep 8:47-52. 2007
    ..This article reviews the latest developments in laser treatment of BPH over the past 2 years and provides a view toward the future of lasers in the treatment of BPH...
  2. doi request reprint Noncontact stimulation of the cavernous nerves in the rat prostate using a tunable-wavelength thulium fiber laser
    Nathaniel M Fried
    Department of Physics and Optical Science, University of North Carolina at Charlotte, North Carolina 28223 0001, USA
    J Endourol 22:409-13. 2008
    ..This study explored laser stimulation of the rat cavernous nerves as a potential alternative to electrical nerve mapping during nerve-sparing radical prostatectomy...
  3. doi request reprint Laser stimulation of the cavernous nerves in the rat prostate, in vivo: optimization of wavelength, pulse energy, and pulse repetition rate
    Nathaniel M Fried
    Department of Physics and Optical Science at the University of North Carolina at Charlotte, NC 28223, USA
    Conf Proc IEEE Eng Med Biol Soc 2008:2777-80. 2008
    ..Optical nerve stimulation may represent a potential intra-operative diagnostic technique for use in laparoscopic and robotic nerve-sparing prostate cancer surgery...
  4. ncbi request reprint Imaging the cavernous nerves in the rat prostate using optical coherence tomography
    Nathaniel M Fried
    Department of Urology, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    Lasers Surg Med 39:36-41. 2007
    ..The rat prostate serves as an excellent model for studying the use of OCT for imaging the CNs, as the rat CN is a large, visible, and distinct bundle allowing for easy identification with OCT in addition to histologic confirmation...
  5. doi request reprint Temperature-controlled optical stimulation of the rat prostate cavernous nerves
    Serhat Tozburun
    University of North Carolina at Charlotte, Department of Physics and Optical Science, Charlotte, North Carolina 28223 0001, USA
    J Biomed Opt 18:067001. 2013
    ..With further development, TC-ONS may provide a rapid, stable, and safe method for intraoperative identification and preservation of the prostate CNs...
  6. doi request reprint Optical coherence tomography of cavernous nerves: a step toward real-time intraoperative imaging during nerve-sparing radical prostatectomy
    Soroush Rais-Bahrami
    James Buchanan Brady Urological Institute, Johns Hopkins Medical Institutions, Bethesda, Maryland 21287, USA
    Urology 72:198-204. 2008
    ..OCT is an imaging modality that allows for real-time, high-resolution, cross-sectional imaging of tissues...
  7. doi request reprint Noninvasive thermal coagulation of deep subsurface tissue structures using a laser probe with integrated contact cooling
    Christopher M Cilip
    Department of Physics and Optical Science, University of North Carolina at Charlotte, NC 28223, USA
    Conf Proc IEEE Eng Med Biol Soc 2008:3657-60. 2008
    ..Liver lesions of 5.8-mm-diameter were created, while preserving the tissue surface to a depth of 1.5 mm. In vivo animal studies are planned to optimize the laser and cooling parameters for potential clinical applications...
  8. ncbi request reprint Side-firing germanium oxide optical fibers for use with erbium:YAG laser
    Anthony K Ngo
    Department of Electrical and Computer Engineering, Johns Hopkins University, Baltimore, Maryland, USA
    J Endourol 20:475-8. 2006
    ..This paper describes the simple construction and characterization of a side-firing germanium oxide fiber for potential use with the Er:YAG laser in endourology...
  9. ncbi request reprint Comparison of germanium oxide fibers with silica and sapphire fiber tips for transmission of erbium: YAG laser radiation
    Travis J Polletto
    Department of Urology, Johns Hopkins University, Baltimore, Maryland 21224, USA
    Lasers Surg Med 38:787-91. 2006
    ..The purpose of this study was to compare the transmission of Er:YAG laser radiation through germanium oxide trunk fibers with silica and sapphire fiber tips for potential use in contact tissue ablation during endoscopy...
  10. ncbi request reprint High-power thulium fiber laser ablation of urinary tissues at 1.94 microm
    Nathaniel M Fried
    Department of Urology, Johns Hopkins School of Medicine, Baltimore, Maryland 21224, USA
    J Endourol 19:25-31. 2005
    ..This paper describes the preliminary testing of a new laser, the thulium fiber laser, as a potential replacement for the holmium:YAG laser for multiple applications in urology...
  11. doi request reprint Infrared laser thermal fusion of blood vessels: preliminary ex vivo tissue studies
    Christopher M Cilip
    University of North Carolina at Charlotte, Department of Physics and Optical Science, Charlotte, NC 28223, USA
    J Biomed Opt 18:58001. 2013
    ....
  12. doi request reprint Wavelet denoising during optical coherence tomography of the prostate nerves using the complex wavelet transform
    Shahab Chitchian
    Department of Physics and Optical Science, University of North Carolina at Charlotte, NC 28223, USA
    Conf Proc IEEE Eng Med Biol Soc 2008:3016-9. 2008
    ..Image quality metrics of the cavernous nerves and signal-to-noise ratio (SNR) were improved significantly using this complex wavelet denoising technique...
  13. doi request reprint Subsurface near-infrared laser stimulation of the periprostatic cavernous nerves
    Serhat Tozburun
    Dept of Physics and Optical Science, University of North Carolina at Charlotte, NC, USA
    J Biophotonics 5:793-800. 2012
    ....
  14. pmc Application of optical coherence tomography and high-frequency ultrasound imaging during noninvasive laser vasectomy
    Christopher M Cilip
    University of North Carolina at Charlotte, Department of Physics and Optical Science, North Carolina 28223, USA
    J Biomed Opt 17:046006. 2012
    ..Both OCT and high HFUS are promising imaging modalities for real-time confirmation of vas occlusion during noninvasive laser vasectomy...
  15. pmc High-frequency ultrasound imaging of noninvasive laser coagulation of the canine vas deferens
    Christopher M Cilip
    Department of Physics and Optical Science, University of North Carolina at Charlotte, Charlotte, NC 28223, USA
    Lasers Surg Med 43:838-42. 2011
    ..In this study, high-frequency ultrasound is used to confirm successful laser thermal coagulation and scarring of the vas in a short-term canine model...
  16. ncbi request reprint Erbium:YAG laser lithotripsy using hybrid germanium/silica optical fibers
    Yubing Yang
    Department of Urology, Johns Hopkins Medical School, JH Bayvuew Medical Center, 4940 Eastern Avenue, Baltimore, MD 21224, USA
    J Endourol 18:830-5. 2004
    ..This paper describes the initial testing of a hybrid germanium oxide/silica optical fiber for potential endoscopic use with the Er:YAG laser...
  17. doi request reprint Combined image-processing algorithms for improved optical coherence tomography of prostate nerves
    Shahab Chitchian
    University of North Carolina at Charlotte, Department of Physics and Optical Science, Charlotte, North Carolina 28223, USA
    J Biomed Opt 15:046014. 2010
    ....
  18. ncbi request reprint Denoising during optical coherence tomography of the prostate nerves via wavelet shrinkage using dual-tree complex wavelet transform
    Shahab Chitchian
    University of North Carolina at Charlotte, Department of Physics and Optical Science, Charlotte, North Carolina 28223, USA
    J Biomed Opt 14:014031. 2009
    ..The cavernous nerve and prostate gland can be separated from discontinuities due to noise, and image quality metrics improvements with a signal-to-noise ratio increase of 14 dB are attained...
  19. doi request reprint Hollow steel tips for reducing distal fiber burn-back during thulium fiber laser lithotripsy
    Thomas C Hutchens
    Optical Science and Engineering Program, University of North Carolina at Charlotte, Charlotte, North Carolina 28223, USA
    J Biomed Opt 18:078001. 2013
    ..Although an increase in stone retropulsion was observed, potential integration of the hollow fiber tip into a stone basket may provide rapid stone vaporization, while minimizing retropulsion...
  20. doi request reprint Detachable microsphere scalpel tips for potential use in ophthalmic surgery with the erbium:YAG laser
    Thomas C Hutchens
    University of North Carolina at Charlotte, Department of Physics and Optical Science, Charlotte, North Carolina
    J Biomed Opt 19:18003. 2014
    ..Detachable microsphere laser scalpel tips may allow surgeons better precision and safety compared to mechanical scalpels when operating on delicate or sensitive areas like the retina. ..
  21. doi request reprint Continuous-wave infrared subsurface optical stimulation of the rat prostate cavernous nerves using a 1490-nm diode laser
    Serhat Tozburun
    Department of Physics and Optical Science, University of North Carolina at Charlotte, Charlotte, NC Harvard Medical School and Wellman Center for Photomedicine, Massachusetts General Hospital, Boston, MA Electronic address
    Urology 82:969-73. 2013
    ..To optimize the infrared laser wavelength and optical nerve stimulation (ONS) parameters for both deep and rapid subsurface cavernous nerve (CN) stimulation in a rat model, in vivo...
  22. doi request reprint Detachable fiber optic tips for use in thulium fiber laser lithotripsy
    Thomas C Hutchens
    Optical Science and Engineering Program, University of North Carolina, Charlotte, North Carolina, USA
    J Biomed Opt 18:038001. 2013
    ..The 1-mm outer-diameter prototype also functioned comparable to previously tested tapered fiber tips...
  23. doi request reprint Noninvasive laser coagulation of the human vas deferens: optical and thermal simulations
    Gino R Schweinsberger
    Department of Physics and Optical Science, University of North Carolina at Charlotte, North Carolina, USA
    Lasers Surg Med 43:443-9. 2011
    ..In this study, Monte Carlo (MC) simulations of light transport through tissue and heat transfer simulations are performed to determine the feasibility of noninvasive laser vasectomy in humans...
  24. pmc Application of an optical clearing agent during noninvasive laser coagulation of the canine vas deferens
    Christopher M Cilip
    University of North Carolina at Charlotte, Department of Physics and Optical Science, Charlotte, North Carolina 28223, USA
    J Biomed Opt 15:048001. 2010
    ..This technique may result in use of a less expensive laser and eliminate the formation of scrotal skin burns during the procedure...
  25. ncbi request reprint High-intensity focused ultrasound ablation of the epididymis in a canine model: a potential alternative to vasectomy
    William W Roberts
    Brady Urological Institute, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21287, USA
    J Endourol 16:621-5. 2002
    ..The epididymis may be a better target than the vas deferens because it is larger, more easily positioned in the HIFU focal zone, and more susceptible to occlusive injury at lower energy levels, thus reducing collateral damage...
  26. doi request reprint Holmium:YAG (lambda = 2,120 nm) versus thulium fiber (lambda = 1,908 nm) laser lithotripsy
    Richard L Blackmon
    Department of Physics and Optical Science, University of North Carolina at Charlotte, Charlotte, North Carolina 28223 000, USA
    Lasers Surg Med 42:232-6. 2010
    ..We hypothesize that this should translate into more efficient laser lithotripsy using the thulium fiber laser. This study directly compares stone vaporization rates for holmium and thulium fiber lasers...
  27. doi request reprint Thulium fiber laser lithotripsy using tapered fibers
    Richard L Blackmon
    Department of Physics and Optical Science, University of North Carolina at Charlotte, Charlotte, North Carolina 28223 0001, USA
    Lasers Surg Med 42:45-50. 2010
    ..This study explores use of a short taper for expanding the Thulium fiber laser beam at the distal tip of a small-core fiber...
  28. ncbi request reprint Subsurface tissue lesions created using an Nd:YAG laser and a sapphire contact cooling probe
    Rahayu Ramli
    Department of Biomedical Engineering, Johns Hopkins University, Baltimore, Maryland, USA
    Lasers Surg Med 35:392-6. 2004
    ..This study investigates deep laser coagulation of tissue in combination with contact cooling of the tissue surface for potential use in noninvasive procedures in urology...
  29. ncbi request reprint Comparison of erbium:yttrium-aluminum-garnet and holmium:yttrium-aluminum-garnet lasers for incision of urethra and bladder neck in an in vivo porcine model
    Ioannis M Varkarakis
    Department of Urology, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    Urology 65:191-5. 2005
    ..To evaluate, in an animal model, differences in wound healing and scar formation in healthy urethra and bladder neck incised with the erbium (Er):yttrium-aluminum-garnet (YAG) and holmium (Ho):YAG lasers...
  30. doi request reprint Fiber-optic manipulation of urinary stone phantoms using holmium:YAG and thulium fiber lasers
    Richard L Blackmon
    University of North Carolina at Charlotte, Department of Physics and Optical Science, 9201 University City Avenue, Charlotte, NC 28223 0001, USA
    J Biomed Opt 18:28001. 2013
    ..With further development, this novel technique may be useful for manipulating stone fragments in the urinary tract...
  31. doi request reprint Enhanced thulium fiber laser lithotripsy using micro-pulse train modulation
    Richard L Blackmon
    University of North Carolina at Charlotte, Department of Physics and Optical Science, 9201 University City Avenue, Charlotte, North Carolina 28223 0001, USA
    J Biomed Opt 17:028002. 2012
    ..TFL operation in MPT mode results in increased stone ablation rates which, with further optimization, may approach levels comparable to Ho:YAG laser lithotripsy in the clinic...
  32. doi request reprint Continuous-wave laser stimulation of the rat prostate cavernous nerves using a compact and inexpensive all single mode optical fiber system
    Serhat Tozburun
    Department of Physics and Optical Science, University of North Carolina at Charlotte, Charlotte, North Carolina 28223, USA
    J Endourol 25:1727-31. 2011
    ..This study demonstrates the feasibility of optical stimulation of the rat CN, in vivo, using a compact, inexpensive all-single-mode fiberoptic system...
  33. doi request reprint Comparison of holmium:YAG and thulium fiber laser lithotripsy: ablation thresholds, ablation rates, and retropulsion effects
    Richard L Blackmon
    University of North Carolina at Charlotte, Department of Physics and Optical Science, 9201 University City Avenue, Charlotte, North Carolina 28223 0001, USA
    J Biomed Opt 16:071403. 2011
    ....
  34. doi request reprint Continuous-wave infrared optical nerve stimulation for potential diagnostic applications
    Serhat Tozburun
    University of North Carolina at Charlotte, Department of Physics and Optical Science, Charlotte, North Carolina 28223 0001, USA
    J Biomed Opt 15:055012. 2010
    ....
  35. doi request reprint Noninvasive laser vasectomy: preliminary ex vivo tissue studies
    Christopher M Cilip
    Department of Physics and Optical Science, University of North Carolina at Charlotte, Charlotte, North Carolina 28223 0001, USA
    Lasers Surg Med 41:203-7. 2009
    ..The development of a completely noninvasive vasectomy technique may eliminate these concerns...
  36. ncbi request reprint High-power laser vaporization of the canine prostate using a 110 W Thulium fiber laser at 1.91 microm
    Nathaniel M Fried
    Department of Urology, Johns Hopkins Medical Institutions, Baltimore, Maryland 21224, USA
    Lasers Surg Med 36:52-6. 2005
    ..This study describes the preliminary testing of a high-power Thulium fiber laser for vaporization of the canine prostate, ex vivo...
  37. pmc Characterization of novel microsphere chain fiber optic tips for potential use in ophthalmic laser surgery
    Thomas C Hutchens
    University of North Carolina at Charlotte, Department of Physics and Optical Science, Center for Optoelectronics and Optical Communications, Charlotte, North Carolina 28223, USA
    J Biomed Opt 17:068004. 2012
    ....
  38. doi request reprint Segmentation of optical coherence tomography images for differentiation of the cavernous nerves from the prostate gland
    Shahab Chitchian
    University of North Carolina at Charlotte, Department of Physics and Optical Science, 9201 University City Boulevard, Charlotte, North Carolina 28223, USA
    J Biomed Opt 14:044033. 2009
    ..058+/-0.019. This algorithm may be useful for implementation in clinical endoscopic OCT systems currently being studied for potential intraoperative diagnostic use in laparoscopic and robotic nerve-sparing prostate cancer surgery...
  39. ncbi request reprint Transmission of Q-switched erbium:YSGG (lambda=2.79 microm) and erbium:YAG (lambda=2.94 microm) laser radiation through germanium oxide and sapphire optical fibres at high pulse energies
    Nathaniel M Fried
    Department of Urology, Johns Hopkins Medical Institutions, 4940 Eastern Avenue, Building A, Baltimore, Maryland, MD 21224, USA
    Lasers Med Sci 19:155-60. 2004
    ..This is the first report of germanium and sapphire fibre optic transmission of Q-switched erbium laser energies of 25-42 mJ per pulse...
  40. doi request reprint Selective laser suture lysis with a compact, low-cost, red diode laser
    Petr Shein
    Department of Physics and Optical Science at the University of North Carolina at Charlotte, NC 28223, USA
    Conf Proc IEEE Eng Med Biol Soc 2008:4358-60. 2008
    ..The red diode laser may represent an inexpensive, compact, and safer alternative laser for use in laser suture lysis during ophthalmic surgery...
  41. ncbi request reprint Subsurface tissue lesions created using an Nd:YAG laser and cryogen cooling
    Rahayu Ramli
    Department of Biomedical Engineering, Johns Hopkins University, Baltimore, Maryland, USA
    J Endourol 17:923-6. 2003
    ..This study investigated deep laser heating of tissue in combination with cryogen cooling of the surface for potential noninvasive targeting of subsurface tissue structures in urology...
  42. ncbi request reprint Rapid sealing and cutting of porcine blood vessels, ex vivo, using a high-power, 1470-nm diode laser
    Nicholas C Giglio
    University of North Carolina at Charlotte, Department of Physics and Optical Science, 9201 University City Boulevard, Charlotte, North Carolina 28223
    J Biomed Opt 19:38002. 2014
    ....
  43. doi request reprint Selective laser vaporization of polypropylene mesh used in treatment of female stress urinary incontinence and pelvic organ prolapse: preliminary studies using a red diode laser
    David Burks
    Deparment of Physics and Optical Science, University of North Carolina at Charlotte, Charlotte, NC 28223, USA
    Lasers Surg Med 44:325-9. 2012
    ..This study explores selective laser vaporization of polypropylene suture/mesh materials commonly used in SUI and POP...
  44. ncbi request reprint Optimization of the Erbium:YAG laser for precise incision of ureteral and urethral tissues: in vitro and in vivo results
    Nathaniel M Fried
    Department of Urology, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    Lasers Surg Med 33:108-14. 2003
    ..The Erbium:YAG laser ablates soft tissues with minimal peripheral damage and may be a promising alternative to cold knife and Holmium:YAG laser for precise incision of urological strictures...
  45. ncbi request reprint Thulium fiber laser lithotripsy: an in vitro analysis of stone fragmentation using a modulated 110-watt Thulium fiber laser at 1.94 microm
    Nathaniel M Fried
    Department of Urology, Johns Hopkins Medical Institutions, Hopkins Bayview Medical Center, 4940 Eastern Avenue, Bldg A, Baltimore, MD 21224, USA
    Lasers Surg Med 37:53-8. 2005
    ..g., prostate). This is the first preliminary study of a high-power Thulium fiber laser for fragmentation of urinary stones...
  46. ncbi request reprint Therapeutic applications of lasers in urology: an update
    Nathaniel M Fried
    Johns Hopkins University School of Medicine, James Buchanan Brady Urological Institute, Biophotonics Laboratory, Baltimore, MD 21224, USA
    Expert Rev Med Devices 3:81-94. 2006
    ..This review provides an update on the most important new clinical and experimental therapeutic applications of lasers in urology over the past 5 years...
  47. ncbi request reprint Hybrid germanium/silica optical fibers for endoscopic delivery of erbium:YAG laser radiation
    Charles A Chaney
    Biophotonics Laboratory, Department of Urology, Johns Hopkins Medical School, Bayview Medical Center, 4940 Eastern Avenue, Baltimore, MD 21224, USA
    Lasers Surg Med 34:5-11. 2004
    ..This study reports the testing of a hybrid germanium/silica fiber capable of delivering Er:YAG laser radiation through a flexible endoscope...
  48. ncbi request reprint Focused ultrasound ablation of the epididymis with use of thermal measurements in a canine model
    Nathaniel M Fried
    Department of Urology, Johns Hopkins Medical School, Baltimore, Maryland 21224, USA
    Fertil Steril 78:609-13. 2002
    ..To explore the epididymis as an alternative anatomical target to the vas deferens for noninvasive male sterilization using therapeutic focused ultrasound...