Ellen Freeman

Summary

Affiliation: University of Pennsylvania
Country: USA

Publications

  1. ncbi A dose-response study of a novel, oral tranexamic formulation for heavy menstrual bleeding
    Ellen W Freeman
    Department of Obstetrics and Gynecology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 5509, USA
    Am J Obstet Gynecol 205:319.e1-7. 2011
  2. ncbi Contribution of the rate of change of antimüllerian hormone in estimating time to menopause for late reproductive-age women
    Ellen W Freeman
    Department of Obstetrics and Gynecology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Fertil Steril 98:1254-9.e1-2. 2012
  3. ncbi Clinical subtypes of premenstrual syndrome and responses to sertraline treatment
    Ellen W Freeman
    Department of Obstetrics Gynecology, the Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Obstet Gynecol 118:1293-300. 2011
  4. ncbi An overview of four studies of a continuous oral contraceptive (levonorgestrel 90 mcg/ethinyl estradiol 20 mcg) on premenstrual dysphoric disorder and premenstrual syndrome
    Ellen W Freeman
    Department of Obstetrics and Gynecology, University of Pennsylvania Medical Center, Philadelphia, PA 19104, USA
    Contraception 85:437-45. 2012
  5. ncbi Anti-mullerian hormone as a predictor of time to menopause in late reproductive age women
    Ellen W Freeman
    Department of Obstetrics Gynecology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    J Clin Endocrinol Metab 97:1673-80. 2012
  6. ncbi Obesity and reproductive hormone levels in the transition to menopause
    Ellen W Freeman
    Department of Obstetrics Gynecology, University of Pennsylvania, Philadelphia, PA, USA
    Menopause 17:718-26. 2010
  7. ncbi Efficacy of escitalopram for hot flashes in healthy menopausal women: a randomized controlled trial
    Ellen W Freeman
    Department of Obstetrics Gynecology, University of Pennsylvania School of Medicine, Philadelphia, USA
    JAMA 305:267-74. 2011
  8. ncbi Association of anti-mullerian hormone levels with obesity in late reproductive-age women
    Ellen W Freeman
    Department of Obstetrics Gynecology, University of Pennsylvania, School of Medicine, Philadelphia, Pennsylvania 19104, USA
    Fertil Steril 87:101-6. 2007
  9. ncbi Associations of hormones and menopausal status with depressed mood in women with no history of depression
    Ellen W Freeman
    Department of Obstetrics Gynecology, University of Pennsylvania School of Medicine, Philadelphia, 19104, USA
    Arch Gen Psychiatry 63:375-82. 2006
  10. ncbi A preliminary study of luteal phase versus symptom-onset dosing with escitalopram for premenstrual dysphoric disorder
    Ellen W Freeman
    Department of Obstetrics and Gynecology, University of Pennsylvania Medical Center, Philadelphia, 19104, USA
    J Clin Psychiatry 66:769-73. 2005

Research Grants

  1. EPIDEMIOLOGIC STUDY OF THE LATE REPRODUCTIVE YEARS
    Ellen Freeman; Fiscal Year: 2005
  2. TREATMENT EVALUATION IN PREMENSTRUAL SYNDROME PATIENTS
    Ellen Freeman; Fiscal Year: 2001
  3. EPIDEMIOLOGIC STUDY OF THE LATE REPRODUCTIVE YEARS
    Ellen Freeman; Fiscal Year: 2009
  4. Core symptoms and profiles in premenstrual syndrome
    Ellen Freeman; Fiscal Year: 2007
  5. EPIDEMIOLOGIC STUDY OF THE LATE REPRODUCTIVE YEARS
    Ellen Freeman; Fiscal Year: 2007
  6. CAREER DEVELOPMENT IN WOMEN'S HEALTH RESEARCH AND GENDE*
    Ellen Freeman; Fiscal Year: 2006
  7. Short-Term vs Long-Term Treatment for Servere PMS
    Ellen Freeman; Fiscal Year: 2006
  8. EPIDEMIOLOGIC STUDY OF THE LATE REPRODUCTIVE YEARS
    Ellen Freeman; Fiscal Year: 2000
  9. TREATMENT EVALUATION IN PREMENSTRUAL SYNDROME PATIENTS
    Ellen Freeman; Fiscal Year: 1992
  10. TREATMENT EVALUATION IN PREMENSTRUAL SYNDROME PATIENTS
    Ellen Freeman; Fiscal Year: 1993

Detail Information

Publications63

  1. ncbi A dose-response study of a novel, oral tranexamic formulation for heavy menstrual bleeding
    Ellen W Freeman
    Department of Obstetrics and Gynecology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 5509, USA
    Am J Obstet Gynecol 205:319.e1-7. 2011
    ..We sought to assess the efficacy and safety of 2 dosing regimens of a novel, oral tranexamic acid formulation (Lysteda; Ferring Pharmaceuticals Inc, Parsippany, NJ) in women with cyclic heavy menstrual bleeding...
  2. ncbi Contribution of the rate of change of antimüllerian hormone in estimating time to menopause for late reproductive-age women
    Ellen W Freeman
    Department of Obstetrics and Gynecology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Fertil Steril 98:1254-9.e1-2. 2012
    ..We hypothesized that the rate of change between two measures of AMH reflects follicular atresia and varies among women independent of age...
  3. ncbi Clinical subtypes of premenstrual syndrome and responses to sertraline treatment
    Ellen W Freeman
    Department of Obstetrics Gynecology, the Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Obstet Gynecol 118:1293-300. 2011
    ..To estimate response of diagnosis and symptom-based subtypes to sertraline treatment...
  4. ncbi An overview of four studies of a continuous oral contraceptive (levonorgestrel 90 mcg/ethinyl estradiol 20 mcg) on premenstrual dysphoric disorder and premenstrual syndrome
    Ellen W Freeman
    Department of Obstetrics and Gynecology, University of Pennsylvania Medical Center, Philadelphia, PA 19104, USA
    Contraception 85:437-45. 2012
    ....
  5. ncbi Anti-mullerian hormone as a predictor of time to menopause in late reproductive age women
    Ellen W Freeman
    Department of Obstetrics Gynecology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    J Clin Endocrinol Metab 97:1673-80. 2012
    ..Anti-mullerian hormone (AMH) has emerged as a marker of ovarian reserve and a possible surrogate measure of reproductive aging...
  6. ncbi Obesity and reproductive hormone levels in the transition to menopause
    Ellen W Freeman
    Department of Obstetrics Gynecology, University of Pennsylvania, Philadelphia, PA, USA
    Menopause 17:718-26. 2010
    ..The aim of this study was to estimate associations of obesity with reproductive hormone levels as women progress from premenopausal to postmenopausal status...
  7. ncbi Efficacy of escitalopram for hot flashes in healthy menopausal women: a randomized controlled trial
    Ellen W Freeman
    Department of Obstetrics Gynecology, University of Pennsylvania School of Medicine, Philadelphia, USA
    JAMA 305:267-74. 2011
    ..Concerns regarding the risks associated with estrogen and progesterone to manage menopausal symptoms have resulted in its declining use and increased interest in nonhormonal treatments with demonstrated efficacy for hot flashes...
  8. ncbi Association of anti-mullerian hormone levels with obesity in late reproductive-age women
    Ellen W Freeman
    Department of Obstetrics Gynecology, University of Pennsylvania, School of Medicine, Philadelphia, Pennsylvania 19104, USA
    Fertil Steril 87:101-6. 2007
    ..To describe anti-mullerian hormone (AMH) levels in healthy late reproductive age women and test the hypothesis that AMH levels are lower in obese compared to non-obese women...
  9. ncbi Associations of hormones and menopausal status with depressed mood in women with no history of depression
    Ellen W Freeman
    Department of Obstetrics Gynecology, University of Pennsylvania School of Medicine, Philadelphia, 19104, USA
    Arch Gen Psychiatry 63:375-82. 2006
    ..Whether depressed mood reported in the transition to menopause by women with no history of depression is associated with menopausal status and changes in reproductive hormones is controversial and lacks scientific information...
  10. ncbi A preliminary study of luteal phase versus symptom-onset dosing with escitalopram for premenstrual dysphoric disorder
    Ellen W Freeman
    Department of Obstetrics and Gynecology, University of Pennsylvania Medical Center, Philadelphia, 19104, USA
    J Clin Psychiatry 66:769-73. 2005
    ..This preliminary study compared the efficacy and tolerability of escitalopram administered at symptom onset or throughout the luteal phase in premenstrual dysphoric disorder (PMDD)...
  11. ncbi Effects of antidepressants on quality of life in women with premenstrual dysphoric disorder
    Ellen W Freeman
    Department of Obstetrics Gynecology, University of Pennsylvania, Philadelphia, Pennsylvania 19104 5509, USA
    Pharmacoeconomics 23:433-44. 2005
    ..Greater awareness of the effectiveness of treatments and reliable measures of the direct and indirect healthcare costs of the disorder when it remains untreated are needed...
  12. ncbi The role of anxiety and hormonal changes in menopausal hot flashes
    Ellen W Freeman
    Department of Obstetrics Gynecology, University of Pennsylvania, Philadelphia, PA 19104, USA
    Menopause 12:258-66. 2005
    ..To estimate the association of anxiety with menopausal hot flashes in the early transition to menopause...
  13. ncbi Symptoms associated with menopausal transition and reproductive hormones in midlife women
    Ellen W Freeman
    Departments of Obstetrics Gynecology, Psychiatry, University of Pennsylvania, 3701 Market Street, Philadelphia, PA 19104, USA
    Obstet Gynecol 110:230-40. 2007
    ....
  14. ncbi Symptoms in the menopausal transition: hormone and behavioral correlates
    Ellen W Freeman
    Department of Obstetrics Gynecology, University of Pennsylvania, Philadelphia, Pennsylvania, USA
    Obstet Gynecol 111:127-36. 2008
    ..To estimate the association of headache, irritability, mood swings, anxiety, and concentration difficulties with menopausal stage and with reproductive hormones in the menopausal transition...
  15. ncbi Temporal associations of hot flashes and depression in the transition to menopause
    Ellen W Freeman
    Departments of Obstetrics Gynecology, University of Pennsylvania School of Medicine, Philadelphia, PA19104 5509, USA
    Menopause 16:728-34. 2009
    ..The aim of this study was to evaluate associations between hot flashes and depressed mood in the menopausal transition and associations of these symptoms with reproductive hormone changes...
  16. ncbi Time to relapse after short- or long-term treatment of severe premenstrual syndrome with sertraline
    Ellen W Freeman
    Department of Obstetrics Gynecology, University of Pennsylvania, School of Medicine, Philadelphia, PA 19104 5509, USA
    Arch Gen Psychiatry 66:537-44. 2009
    ..The duration of treatment after achieving a satisfactory response is unknown in the treatment of premenstrual syndrome. This information is needed in view of the improvement provided by medication vs the adverse effects and costs of drugs...
  17. ncbi Associations of depression with the transition to menopause
    Ellen W Freeman
    Department of Obstetrics Gynecology, University of Pennsylvania, Philadelphia, PA, USA
    Menopause 17:823-7. 2010
    ....
  18. ncbi Therapeutic management of premenstrual syndrome
    Ellen W Freeman
    Departments of Obstetrics Gynecology and Psychiatry, University of Pennsylvania, Philadelphia, PA 19104, USA
    Expert Opin Pharmacother 11:2879-89. 2010
    ..Premenstrual syndrome (PMS) is among the most common health problems reported by reproductive-age women. Estimates indicate that up to 25% of women may warrant treatment for the distress or impaired functioning associated with the symptoms...
  19. ncbi Core symptoms that discriminate premenstrual syndrome
    Ellen W Freeman
    Department of Obstetrics Gynecology, University of Pennsylvania, Philadelphia, PA 19104, USA
    J Womens Health (Larchmt) 20:29-35. 2011
    ..To identify core symptoms that discriminate premenstrual syndrome (PMS) in prospective daily diary ratings and determine the association of these symptoms with functional impairment...
  20. ncbi Duration of menopausal hot flushes and associated risk factors
    Ellen W Freeman
    Department of Obstetrics Gynecology, the Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, Pennsylvania, USA
    Obstet Gynecol 117:1095-104. 2011
    ..To estimate the duration of moderate-to-severe menopausal hot flushes and identify potential risk factors for hot flush duration...
  21. ncbi Follicular phase hormone levels and menstrual bleeding status in the approach to menopause
    E W Freeman
    Department of Obstetrics and Gynecology, University of Pennsylvania, School of Medicine, Philadelphia, PA 19104, USA
    Fertil Steril 83:383-92. 2005
    ....
  22. ncbi Hormones and menopausal status as predictors of depression in women in transition to menopause
    Ellen W Freeman
    Departments of Obstetrics Gynecology, University of Pennsylvania School of Medicine, Mudd Suite, 3701 Market Street, Philadelphia, PA 19104 5509, USA
    Arch Gen Psychiatry 61:62-70. 2004
    ..Associations between depressed mood and hormonal changes during transition to menopause are controversial. To our knowledge, there has been no prospective study of these associations in women commencing when they are premenopausal...
  23. ncbi Psychometric properties of a menopausal symptom list
    Ellen W Freeman
    Department of Obstetrics Gynecology, University of Pennsylvania, Philadelphia 19104, USA
    Menopause 10:258-65. 2003
    ..To determine psychometric properties of a brief menopause symptom list and its sensitivity to menopausal status in a population-based cohort of late reproductive-age women...
  24. ncbi Current update of hormonal and psychotropic drug treatment of premenstrual dysphoric disorder
    Ellen W Freeman
    Department of Obstetrics and Gynecology, University of Pennsylvania Medical Center, 3400 Spruce Street, 2 Dulles, Mudd Suite, Philadelphia, PA 19104, USA
    Curr Psychiatry Rep 4:435-40. 2002
    ..The results of a meta-analysis of the published trials of progesterone and progestins further indicate that these hormones are not effective in the management of PMDD...
  25. ncbi Reliability and validity of a daily diary for premenstrual syndrome
    E W Freeman
    Department of Psychiatry, University of Pennsylvania Medical Center, Philadelphia 19104 4283, USA
    Psychiatry Res 65:97-106. 1996
    ..The moderate correlations of the DSR with other standard symptom measures add to the evidence that PMS overlaps with other mood disorders at the premenstrual time but is not simply a brief depression or a truncated anxiety disorder...
  26. ncbi Treatment of premenstrual syndrome with a carbohydrate-rich beverage
    E W Freeman
    Department of Obstetrics and Gynecology, University of Pennsylvania, Philadelphia, USA
    Int J Gynaecol Obstet 77:253-4. 2002
  27. ncbi Continuous or intermittent dosing with sertraline for patients with severe premenstrual syndrome or premenstrual dysphoric disorder
    Ellen W Freeman
    Department of Obstetrics Gynecology, University of Pennsylvania School of Medicine, Philadelphia 19104 5509, USA
    Am J Psychiatry 161:343-51. 2004
    ....
  28. ncbi Venlafaxine in the treatment of premenstrual dysphoric disorder
    E W Freeman
    Department of Obstetrics Gynecology, School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Obstet Gynecol 98:737-44. 2001
    ..To evaluate the efficacy and safety of venlafaxine, a new-generation antidepressant that selectively inhibits serotonin and norepinephrine reuptake, in the treatment of premenstrual dysphoric disorder (PMDD)...
  29. ncbi Full- or half-cycle treatment of severe premenstrual syndrome with a serotonergic antidepressant
    E W Freeman
    Department of Obstetrics Gynecology, University of Pennsylvania Medical Center, Philadelphia 19104, USA
    J Clin Psychopharmacol 19:3-8. 1999
    ....
  30. ncbi Predictors of response to sertraline treatment of severe premenstrual syndromes
    E W Freeman
    Department of Obstetrics Gynecology, School of Medicine, University of Pennsylvania, Philadelphia, USA
    J Clin Psychiatry 61:579-84. 2000
    ..The current study examined pretreatment demographic, medical history, and clinical symptom predictors of sertraline response in PMS and PMDD treatment...
  31. ncbi Differential response to antidepressants in women with premenstrual syndrome/premenstrual dysphoric disorder: a randomized controlled trial
    E W Freeman
    Department of Obstetrics Gynecology, School of Medicine, University of Pennsylvania, Philadelphia 19104, USA
    Arch Gen Psychiatry 56:932-9. 1999
    ....
  32. ncbi Characteristics of placebo responses in medical treatment of premenstrual syndrome
    E W Freeman
    Department of Obstetrics Gynecology, University of Pennsylvania Medical Center, Philadelphia 19104, USA
    Am J Psychiatry 156:1403-8. 1999
    ..This study characterizes the responses to placebo medication of patients with premenstrual syndrome (PMS) who were randomly assigned in controlled treatment trials. Possible predictors of placebo response were also examined...
  33. ncbi Factors that influence entry into stages of the menopausal transition
    Mary D Sammel
    Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, PA, USA
    Menopause 16:1218-27. 2009
    ..The aim of this study was to estimate the probabilities and identify risk factors for entering the menopausal transition and moving into each subsequent transition stage...
  34. ncbi Investigating the associations between nocturia and sleep disorders in perimenopausal women
    Manish Gopal
    Division of Urogynecology, University of Pennsylvania, Philadelphia, Pennsylvania, USA
    J Urol 180:2063-7. 2008
    ..We determined the associations between nocturia and sleep disorders in perimenopausal women...
  35. ncbi Impact of cancer therapies on ovarian reserve
    Clarisa R Gracia
    Department of Obstetrics Gynecology, Children s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA
    Fertil Steril 97:134-40.e1. 2012
    ..To determine whether measures of ovarian reserve differ between females exposed to cancer therapies in a dose-dependent manner as compared with healthy controls of similar age and late reproductive age...
  36. ncbi Effect of physical activity on menopausal symptoms among urban women
    Deborah B Nelson
    Department of Public Health, College of Health Professions, Temple University, Philadelphia, PA 19122, USA
    Med Sci Sports Exerc 40:50-8. 2008
    ..To determine whether physical activity, measured by expended kilocalories per week (kcal.wk), decreases the risk of menopausal symptoms among African American and Caucasian women...
  37. ncbi Acute consequences of the menopausal transition: the rise of common menopausal symptoms
    Clarisa R Gracia
    Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    Endocrinol Metab Clin North Am 33:675-89. 2004
    ..This article re-views the current evidence regarding the acute symptoms of the menopausal transition, including vasomotor symptoms, mood changes, sleep problems, and changes in sexual functioning...
  38. ncbi Allopregnanolone levels and symptom improvement in severe premenstrual syndrome
    Ellen W Freeman
    Department of Obstetrics Gynecology, University of Pennsylvania, Philadelphia 19104, USA
    J Clin Psychopharmacol 22:516-20. 2002
    ....
  39. ncbi Hot flashes during pregnancy: a comparative study
    Laura J Hanisch
    Department of Psychiatry, University of Pennsylvania, Philadelphia, PA, United States
    Eur J Obstet Gynecol Reprod Biol 151:38-40. 2010
    ..To conduct a preliminary study assessing the association of hot flashes with pregnancy...
  40. ncbi Effect of hormone metabolism genotypes on steroid hormone levels and menopausal symptoms in a prospective population-based cohort of women experiencing the menopausal transition
    Timothy R Rebbeck
    Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 6021, USA
    Menopause 17:1026-34. 2010
    ..This study evaluated whether genes involved in the metabolism of steroid hormones are associated with hormone levels or menopausal symptoms...
  41. ncbi Hot flashes and panic attacks: a comparison of symptomatology, neurobiology, treatment, and a role for cognition
    Laura J Hanisch
    Department of Psychiatry, University of Pennsylvania, USA
    Psychol Bull 134:247-69. 2008
    ..This model yields readily testable hypotheses and may provide a template for exploring the role of cognition in the frequency and severity of hot flashes and, in turn, a basis for the development of nonpharmacological treatments...
  42. ncbi Weight gain among women in the late reproductive years
    Mary D Sammel
    Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, 423 Guardian Drive, 605 Blockly Hall, Philadelphia, PA 19104, USA
    Fam Pract 20:401-9. 2003
    ..Given the impact of obesity on mortality and morbidity in women, we evaluated correlates of weight gain in women ages 35-47 years...
  43. ncbi Predictors of sleep quality in women in the menopausal transition
    Grace W Pien
    Division of Sleep Medicine, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    Sleep 31:991-9. 2008
    ..To determine associations between menopausal status, reproductive hormone levels, menopausal symptoms, and poor sleep quality...
  44. ncbi Tubal ligation does not affect hormonal changes during the early menopausal transition
    Deborah B Nelson
    Department of Biostatistics and Epidemiology, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 6021, USA
    Contraception 71:104-10. 2005
    ..To determine if women with a bilateral tubal ligation (BTL) were more likely to experience hormonal changes indicative of the transition to menopause or an increase in menopausal symptoms compared to women without a BTL...
  45. ncbi Defining menopause status: creation of a new definition to identify the early changes of the menopausal transition
    Clarisa R Gracia
    Department of Obstetrics Gynecology, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    Menopause 12:128-35. 2005
    ..The objective of this study was to determine which definition captures the earliest hormonal changes in the menopausal transition...
  46. ncbi Predicting participation in prospective studies of ovarian aging
    Deborah B Nelson
    Department of Biostatistics and Epidemiology, Center for Clinical Epidemiology and Biostatistics, Hospital of the University of Pennsylvania, University of Pennsylvania School of Medicine, Philadelphia, USA
    Menopause 11:543-8. 2004
    ....
  47. ncbi Luteal phase administration of agents for the treatment of premenstrual dysphoric disorder
    Ellen W Freeman
    Departments of Obstetrics Gynecology and Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania, USA
    CNS Drugs 18:453-68. 2004
    ..Progesterone has consistently failed to show efficacy for severe PMS/PMDD in large, randomised, placebo-controlled trials...
  48. ncbi The relationship between obesity and race on inhibin B during the menopause transition
    Clarisa R Gracia
    Department of Obstetrics Gynecology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Menopause 12:559-66. 2005
    ..The purpose of this study was to determine the relationship among inhibin B levels, body mass index (BMI), and race during the menopause transition...
  49. ncbi Predictors of decreased libido in women during the late reproductive years
    Clarisa R Gracia
    Department of Obstetrics Gynecology, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    Menopause 11:144-50. 2004
    ..To identify risk factors for decreased libido among women in the late reproductive years...
  50. ncbi Hormones and sexuality during transition to menopause
    Clarisa R Gracia
    Department of Obstetrics Gynecology, Center for Clinical Epidemiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
    Obstet Gynecol 109:831-40. 2007
    ..To examine the relationship between reproductive hormonal dynamics and sexual dysfunction assessed in a cohort of women approaching menopause...
  51. ncbi Association of physical activity with reproductive hormones: the Penn Ovarian Aging Study
    Kathryn H Schmitz
    Center for Clinical Epidemiology and Biostatistics, Department of Biostatistics and Epidemiology, 423 Guardian Drive, 921 Blockley Hall, Philadelphia, PA 19104, USA
    Cancer Epidemiol Biomarkers Prev 16:2042-7. 2007
    ..Few studies have examined associations of physical activity on hormone levels. None have examined the potential effect of the menopausal transition on the associations between physical activity and reproductive hormone levels...
  52. ncbi Body size affects measures of ovarian reserve in late reproductive age women
    H Irene Su
    Department of Obstetrics, Division of Reproductive Endocrinology and Infertility, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Menopause 15:857-61. 2008
    ..To examine the association between obesity and serum and ultrasound measures of ovarian reserve in late reproductive age women...
  53. ncbi Citalopram in PMS patients with prior SSRI treatment failure: a preliminary study
    Ellen W Freeman
    Departments of Obstetrics/Gynecology, University of Pennsylvania Medical Center, Philadelphia, Pennsylvania, USA
    J Womens Health Gend Based Med 11:459-64. 2002
    ..CONCLUSIONS: These results from a small number of subjects with open-label treatment must be viewed as preliminary but suggest that citalopram treatment is effective for PMS patients who failed previous SSRI treatment...
  54. ncbi Association of change in estradiol to lower urinary tract symptoms during the menopausal transition
    Manish Gopal
    Division of Urogynecology, Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Obstet Gynecol 112:1045-52. 2008
    ..To estimate the relationship between changes in estradiol (E2) levels over time and lower urinary tract symptoms in premenopausal women as they transition to menopause...
  55. ncbi Insulin sensitivity, food intake, and cravings with premenstrual syndrome: a pilot study
    Kimberly K Trout
    University of Pennsylvania School of Nursing, Philadelphia, Pennsylvania, USA
    J Womens Health (Larchmt) 17:657-65. 2008
    ..The objective of this pilot study was to evaluate possible differences in insulin sensitivity, food intake, and cravings between the follicular and luteal phases of the menstrual cycle in women with premenstrual syndrome (PMS)...
  56. ncbi Antimullerian hormone and inhibin B are hormone measures of ovarian function in late reproductive-aged breast cancer survivors
    H Irene Su
    Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
    Cancer 116:592-9. 2010
    ....
  57. ncbi Summary of the National Institute on Aging-sponsored conference on depressive symptoms and cognitive complaints in the menopausal transition
    Pauline M Maki
    Department of Psychiatry, University of Illinois, Chicago, IL, USA
    Menopause 17:815-22. 2010
    ....
  58. ncbi Are there differential symptom profiles that improve in response to different pharmacological treatments of premenstrual syndrome/premenstrual dysphoric disorder?
    Uriel Halbreich
    Biobehavior Program, Department of Psychiatry, State University of New York at Buffalo, New York 14214, USA
    CNS Drugs 20:523-47. 2006
    ..Such information would also improve understanding of the putative pathophysiological mechanisms underlying PMS and PMDD, and may point to a more specific diagnosis of these conditions...
  59. ncbi Premenstrual syndrome (PMS) in adolescents: severity and impairment
    Michelle Vichnin
    Departments of Obstetrics/Gynecology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    J Pediatr Adolesc Gynecol 19:397-402. 2006
    ..Further study is warranted to confirm these results with prospective assessment of PMS and to evaluate treatments for adolescents who have clinically significant PMS...
  60. ncbi Premenstrual syndrome and premenstrual dysphoric disorder: definitions and diagnosis
    Ellen W Freeman
    Department of Obstetrics/Gynecology, Mudd Suite, 3701 Market Street, Philadelphia, PA 19104-5509, USA
    Psychoneuroendocrinology 28:25-37. 2003
    ..Diagnostic criteria for PMS must recognize the broad range of symptoms, the temporal pattern of the symptoms and the critical issue of symptom severity, which differentiates clinically significant PMS from normal menstrual cycle changes...
  61. ncbi Menstrual cycle effects on insulin sensitivity in women with type 1 diabetes: a pilot study
    Kimberly K Trout
    University of Pennsylvania School of Nursing, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    Diabetes Technol Ther 9:176-82. 2007
    ..This pilot study's objective was to evaluate possible differences in insulin sensitivity between follicular and luteal phases in women with type 1 diabetes...
  62. ncbi Pilot study of racial differences and longitudinal changes in inhibin B in the late reproductive years
    Michelle Battistini
    Fertil Steril 77:193-5. 2002
  63. ncbi A pilot naturalistic follow-up of extended sertraline treatment for severe premenstrual syndrome
    Ellen W Freeman
    J Clin Psychopharmacol 24:351-3. 2004

Research Grants40

  1. EPIDEMIOLOGIC STUDY OF THE LATE REPRODUCTIVE YEARS
    Ellen Freeman; Fiscal Year: 2005
    ....
  2. TREATMENT EVALUATION IN PREMENSTRUAL SYNDROME PATIENTS
    Ellen Freeman; Fiscal Year: 2001
    ....
  3. EPIDEMIOLOGIC STUDY OF THE LATE REPRODUCTIVE YEARS
    Ellen Freeman; Fiscal Year: 2009
    ..abstract_text> ..
  4. Core symptoms and profiles in premenstrual syndrome
    Ellen Freeman; Fiscal Year: 2007
    ..Further information will contribute to improved health care for women in their reproductive years. ..
  5. EPIDEMIOLOGIC STUDY OF THE LATE REPRODUCTIVE YEARS
    Ellen Freeman; Fiscal Year: 2007
    ....
  6. CAREER DEVELOPMENT IN WOMEN'S HEALTH RESEARCH AND GENDE*
    Ellen Freeman; Fiscal Year: 2006
    ..The BIRCWH program will track the career trajectories of Scholars and will continue to serve as a resource in terms of career counseling and research advice. ..
  7. Short-Term vs Long-Term Treatment for Servere PMS
    Ellen Freeman; Fiscal Year: 2006
    ....
  8. EPIDEMIOLOGIC STUDY OF THE LATE REPRODUCTIVE YEARS
    Ellen Freeman; Fiscal Year: 2000
    ....
  9. TREATMENT EVALUATION IN PREMENSTRUAL SYNDROME PATIENTS
    Ellen Freeman; Fiscal Year: 1992
    ....
  10. TREATMENT EVALUATION IN PREMENSTRUAL SYNDROME PATIENTS
    Ellen Freeman; Fiscal Year: 1993
    ..Information on the course of PMS symptoms is important for understanding its occurrence and chronicity, which reduces the quality of life and affects the use of costly medical resources...
  11. EPIDEMIOLOGIC STUDY OF THE LATE REPRODUCTIVE YEARS
    Ellen W Freeman; Fiscal Year: 2010
    ..abstract_text> ..