S A Fraser

Summary

Affiliation: University of Nevada
Country: USA

Publications

  1. ncbi request reprint Calreticulin, a component of the endoplasmic reticulum and of cytotoxic lymphocyte granules, regulates perforin-mediated lysis in the hemolytic model system
    S A Fraser
    Cell and Molecular Biology Program, University of Nevada, Reno 89557 0046, USA
    Biochem Cell Biol 76:881-7. 1998
  2. ncbi request reprint Perforin lytic activity is controlled by calreticulin
    S A Fraser
    Cell and Molecular Biology Program, School of Medicine and College of Agriculture, University of Nevada, Reno, NV 89557, USA
    J Immunol 164:4150-5. 2000

Collaborators

Detail Information

Publications2

  1. ncbi request reprint Calreticulin, a component of the endoplasmic reticulum and of cytotoxic lymphocyte granules, regulates perforin-mediated lysis in the hemolytic model system
    S A Fraser
    Cell and Molecular Biology Program, University of Nevada, Reno 89557 0046, USA
    Biochem Cell Biol 76:881-7. 1998
    ..These observations open the possibilities that membrane-bound calreticulin prevents hydrophobic entry of perforin into membranes and (or) prevents perforin from assembling into polyperforin pores...
  2. ncbi request reprint Perforin lytic activity is controlled by calreticulin
    S A Fraser
    Cell and Molecular Biology Program, School of Medicine and College of Agriculture, University of Nevada, Reno, NV 89557, USA
    J Immunol 164:4150-5. 2000
    ..We propose a novel model in which calreticulin stabilizes membranes to prevent polyperforin pore formation...