Teresa R Franklin

Summary

Affiliation: University of Pennsylvania
Country: USA

Publications

  1. pmc A VBM study demonstrating 'apparent' effects of a single dose of medication on T1-weighted MRIs
    Teresa R Franklin
    Department of Psychiatry, Center for Studies of Addiction, University of Pennsylvania School of Medicine, 3900 Chestnut Street, Philadelphia, PA 19104, USA
    Brain Struct Funct 218:97-104. 2013
  2. pmc Dopamine transporter genotype modulation of neural responses to smoking cues: confirmation in a new cohort
    Teresa R Franklin
    Research Assistant Professor of Neuroscience, Addiction Treatment Research Center, Department of Psychiatry, University of Pennsylvania School of Medicine, 3900 Chestnut Street, Philadelphia, PA 19104, USA
    Addict Biol 16:308-22. 2011
  3. pmc Effects of varenicline on smoking cue–triggered neural and craving responses
    Teresa Franklin
    Department of Psychiatry, University of Pennsylvania and Veterans Affairs Medical Center, Philadelphia, PA 19104, USA
    Arch Gen Psychiatry 68:516-26. 2011
  4. pmc The GABA B agonist baclofen reduces cigarette consumption in a preliminary double-blind placebo-controlled smoking reduction study
    Teresa R Franklin
    Department of Psychiatry, University of Pennsylvania, Philadelphia School of Medicine, PA 19104, USA
    Drug Alcohol Depend 103:30-6. 2009
  5. pmc DAT genotype modulates brain and behavioral responses elicited by cigarette cues
    Teresa R Franklin
    Department of Psychiatry, Addiction Treatment Research Center, University of Pennsylvania and Philadelphia VA Medical Center, Philadelphia, PA 19104, USA
    Neuropsychopharmacology 34:717-28. 2009
  6. pmc Menstrual cycle phase at quit date predicts smoking status in an NRT treatment trial: a retrospective analysis
    Teresa R Franklin
    Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania 19104 6178, USA
    J Womens Health (Larchmt) 17:287-92. 2008
  7. ncbi request reprint Limbic activation to cigarette smoking cues independent of nicotine withdrawal: a perfusion fMRI study
    Teresa R Franklin
    Department of Psychiatry, Addiction Treatment Research Center, University of Pennsylvania, 3900 Chestnut Street, Philadelphia, PA 19104, USA
    Neuropsychopharmacology 32:2301-9. 2007
  8. ncbi request reprint Retrospective study: influence of menstrual cycle on cue-induced cigarette craving
    Teresa R Franklin
    Addiction Treatment Research Center, Department of Psychiatry, University of Pennsylvania, Veteran s Administration Hospital of Philadelphia, USA
    Nicotine Tob Res 6:171-5. 2004
  9. pmc Reward-related brain response and craving correlates of marijuana cue exposure: a preliminary study in treatment-seeking marijuana-dependent subjects
    Marina Goldman
    Department of Psychiatry, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, USA
    J Addict Med 7:8-16. 2013
  10. pmc Nipping cue reactivity in the bud: baclofen prevents limbic activation elicited by subliminal drug cues
    Kimberly A Young
    Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, Department of Physiology and Pharmacology, School of Medicine, Wake Forest University, Winston Salem, North Carolina 27157, and Philadelphia VA Medical Center, Philadelphia, Pennsylvania 19104
    J Neurosci 34:5038-43. 2014

Research Grants

  1. Perfusion fMRI of Cue-Induced Nicotine Craving
    Teresa Franklin; Fiscal Year: 2005

Detail Information

Publications18

  1. pmc A VBM study demonstrating 'apparent' effects of a single dose of medication on T1-weighted MRIs
    Teresa R Franklin
    Department of Psychiatry, Center for Studies of Addiction, University of Pennsylvania School of Medicine, 3900 Chestnut Street, Philadelphia, PA 19104, USA
    Brain Struct Funct 218:97-104. 2013
    ....
  2. pmc Dopamine transporter genotype modulation of neural responses to smoking cues: confirmation in a new cohort
    Teresa R Franklin
    Research Assistant Professor of Neuroscience, Addiction Treatment Research Center, Department of Psychiatry, University of Pennsylvania School of Medicine, 3900 Chestnut Street, Philadelphia, PA 19104, USA
    Addict Biol 16:308-22. 2011
    ..Despite heterogeneity introduced by a host of factors, including variance in other genes involved in smoking behavior, we confirm that DAT genotype predicts the direction and location of neural responses to SCs...
  3. pmc Effects of varenicline on smoking cue–triggered neural and craving responses
    Teresa Franklin
    Department of Psychiatry, University of Pennsylvania and Veterans Affairs Medical Center, Philadelphia, PA 19104, USA
    Arch Gen Psychiatry 68:516-26. 2011
    ....
  4. pmc The GABA B agonist baclofen reduces cigarette consumption in a preliminary double-blind placebo-controlled smoking reduction study
    Teresa R Franklin
    Department of Psychiatry, University of Pennsylvania, Philadelphia School of Medicine, PA 19104, USA
    Drug Alcohol Depend 103:30-6. 2009
    ..These preliminary results demonstrate provisional evidence of the utility of baclofen to aid in smoking cessation and indicate further investigation...
  5. pmc DAT genotype modulates brain and behavioral responses elicited by cigarette cues
    Teresa R Franklin
    Department of Psychiatry, Addiction Treatment Research Center, University of Pennsylvania and Philadelphia VA Medical Center, Philadelphia, PA 19104, USA
    Neuropsychopharmacology 34:717-28. 2009
    ..These results provide evidence that genetic variation in the DAT gene contributes to the neural and behavioral responses elicited by smoking cues...
  6. pmc Menstrual cycle phase at quit date predicts smoking status in an NRT treatment trial: a retrospective analysis
    Teresa R Franklin
    Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania 19104 6178, USA
    J Womens Health (Larchmt) 17:287-92. 2008
    ..However, no experimental data have been published to support this claim. Our objective was to determine whether MC phase affected smoking status in premenopausal female smokers participating in a smoking cessation treatment trial...
  7. ncbi request reprint Limbic activation to cigarette smoking cues independent of nicotine withdrawal: a perfusion fMRI study
    Teresa R Franklin
    Department of Psychiatry, Addiction Treatment Research Center, University of Pennsylvania, 3900 Chestnut Street, Philadelphia, PA 19104, USA
    Neuropsychopharmacology 32:2301-9. 2007
    ....
  8. ncbi request reprint Retrospective study: influence of menstrual cycle on cue-induced cigarette craving
    Teresa R Franklin
    Addiction Treatment Research Center, Department of Psychiatry, University of Pennsylvania, Veteran s Administration Hospital of Philadelphia, USA
    Nicotine Tob Res 6:171-5. 2004
    ..05). The suppressed craving response in FFemales suggests an influence of cycle phase on cue-induced craving...
  9. pmc Reward-related brain response and craving correlates of marijuana cue exposure: a preliminary study in treatment-seeking marijuana-dependent subjects
    Marina Goldman
    Department of Psychiatry, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, USA
    J Addict Med 7:8-16. 2013
    ....
  10. pmc Nipping cue reactivity in the bud: baclofen prevents limbic activation elicited by subliminal drug cues
    Kimberly A Young
    Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, Department of Physiology and Pharmacology, School of Medicine, Wake Forest University, Winston Salem, North Carolina 27157, and Philadelphia VA Medical Center, Philadelphia, Pennsylvania 19104
    J Neurosci 34:5038-43. 2014
    ..005; cluster corrected at p < 0.05). These results suggest that baclofen may inhibit the earliest type of drug cue-induced motivational processing-that which occurs outside of awareness-before it evolves into a less manageable state. ..
  11. pmc Modulation of resting brain cerebral blood flow by the GABA B agonist, baclofen: a longitudinal perfusion fMRI study
    Teresa R Franklin
    Department of Psychiatry, University of Pennsylvania, Center for Studies of Addiction and VA Medical Center, Philadelphia, PA, USA franklin
    Drug Alcohol Depend 117:176-83. 2011
    ..Its mechanism in humans is unknown. Here, we used continuous arterial spin labeled (CASL) perfusion fMRI to examine baclofen's effects on blood flow in the human brain...
  12. pmc Acute baclofen diminishes resting baseline blood flow to limbic structures: a perfusion fMRI study
    Teresa R Franklin
    Department of Psychiatry, University of Pennsylvania, Philadelphia, PA 19104, USA franklin
    Drug Alcohol Depend 125:60-6. 2012
    ..In the present study, we hypothesized that a single dose of baclofen would have effects similar to repeated dosing...
  13. ncbi request reprint Decreased gray matter concentration in the insular, orbitofrontal, cingulate, and temporal cortices of cocaine patients
    Teresa R Franklin
    Addiction Treatment Research Center, Department of Psychiatry, University of Pennsylvania and Philadelphia VA Medical Center, Philadelphia, PA 19104 6178, USA
    Biol Psychiatry 51:134-42. 2002
    ..To date, a focal structural analysis of the brains of cocaine patients has not been undertaken...
  14. pmc Neural correlates of attentional bias for smoking cues: modulation by variance in the dopamine transporter gene
    Reagan R Wetherill
    Department of Psychiatry, University of Pennsylvania, Philadelphia, PA, USA
    Addict Biol 19:294-304. 2014
    ..Findings suggest that genetic variation in the DAT gene influences brain responses associated with attentional bias; thus, providing additional support for a SC-vulnerable endophenotype. ..
  15. doi request reprint Neural responses to subliminally presented cannabis and other emotionally evocative cues in cannabis-dependent individuals
    Reagan R Wetherill
    Department of Psychiatry, University of Pennsylvania, 3900 Chestnut Street, Philadelphia, PA, 19104, USA
    Psychopharmacology (Berl) 231:1397-407. 2014
    ..Activation of reward neurocircuitry may provoke craving and perhaps prime an individual for subsequent drug-seeking behaviors...
  16. pmc The impact of sex on brain responses to smoking cues: a perfusion fMRI study
    Reagan R Wetherill
    Department of Psychiatry, University of Pennsylvania, Philadelphia, PA 19104, USA
    Biol Sex Differ 4:9. 2013
    ..The current study examines the impact of sex on brain responses to smoking cues...
  17. pmc Sex differences in resting state neural networks of nicotine-dependent cigarette smokers
    Reagan R Wetherill
    Department of Psychiatry, University of Pennsylvania, Philadelphia, PA 19104, USA Electronic address
    Addict Behav 39:789-92. 2014
    ....
  18. ncbi request reprint Conceptual, methodological, and analytical issues in the study of relapse
    James R McKay
    University of Pennsylvania, Treatment Research Center, Philadelphia 19104, USA
    Clin Psychol Rev 26:109-27. 2006
    ..Nevertheless, important methodological advances have been and continue to be made in the study of relapse, and our knowledge about the nature and process of relapse has increased considerably over the past 10 years...

Research Grants1

  1. Perfusion fMRI of Cue-Induced Nicotine Craving
    Teresa Franklin; Fiscal Year: 2005
    ..Thus, research into its neurological underpinnings is critical in guiding the development of behavioral and pharmacological therapies to battle nicotine addiction. ..